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PROFESSOR | Radiology

Biography

Willem J.M. Mulder, Ph.D. is an Associate Professor in the Department of Radiology at Mount Sinai School of Medicine in New York City. Dr. Mulder obtained a M.Sc. in Chemistry at the Utrecht University (the Netherlands) in 2001 and his Ph.D. in Biomedical Engineering from the Eindhoven University of Technology (the Netherlands) in 2006. Thereafter, he was appointed Assistant Professor of Radiology at Mount Sinai’s http://www.mssm.edu/research/institutes/translational-and-molecular-imaging-institute Translational and Molecular Imaging Institute (TMII) and founded the Nanomedicine Laboratory in October 2006. In July 2012 Dr. Mulder was appointed Associate Professor of Radiology. Dr. Mulder is a renowned investigator in the filed of cardiovascular nanomedicine and the focus of his research is on the development of translational nanomedical approaches towards molecular imaging and targeted therapy of cancer and cardiovascular disease (Nat Rev Drug Discov. 2011;10:835-52; Acc Chem Res. 2009 Jul 21;42(7):904-14). He has authored more than 75 peer-reviewed publications, 10 book chapters, and over 150 meeting presentations. He is currently the Principal Investigator of a National Institutes of Health’s National Cancer Institute R01 grant and serves as a Principal Investigator for one of the projects of a recent large award from the National Heart Lung and Blood Institute Program of Excellence in Nanotechnology (PIs Zahi A. Fayad and Robert Langer). Dr. Mulder trained more than 20 postdocs and students and currently leads a team of 5 postdocs, 2 technicians and 5 (Ph.D.) students. Multi-Disciplinary Training Area Biophysics and Systems Pharmacology [BSP] Education MSc, Utrecht University PhD, Eindhoven University of Technology Language English

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  • Dendrimers Improve Apolipoprotein Nanoparticle mRNA Delivery to Immune Cells

    Trines, M. M., Hoorn, D., Hofstraat, S. R. J., Zwolsman, R. C., Anbergen, T., Versteeg, I., van Elsas, Y., Deckers, J., Hendrikx, M. M. A., Kleuskens, T., Darwish, Y. B., Ros, G. W. B., Dijkstra, S. F., Priem, B., Timmers, M., Fransen, P. M., Pouderoijen, M. J., de Waal, B. F. M., Meijer, E. W. & Beldman, T. J. & 5 others, Toner, Y. C., Kluza, E., Mulder, W. J. M., Janssen, H. M. & van der Meel, R., 13 Jan 2026, In: Advanced Materials. 38, 3, e04830.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    5 Scopus citations
  • Immuno-imaging in solid organ transplantation

    Maas, R. J. F., Versteeg, I., de Jong, L. C., Fayad, Z., Aarntzen, E. H. J. G., Mulder, W. J. M., Teunissen, A. J. P. & Duivenvoorden, R., 2026, (Accepted/In press) In: American Journal of Transplantation.

    Research output: Contribution to journalReview articlepeer-review

    Open Access
  • Systemically inducing trained immunity overcomes solid tumors’ immunosuppressive microenvironment

    Priem, B., Willemsen, L., Anbergen, T., Elsas, Y. V., Deckers, J., Schrijver, D. P., Hofstraat, S. R. J., Messing, I. V., Munitz, J., Honing, D., Prévot, G., Toner, Y. C., Morla, J., Wang, W., Ranzenigo, A., Sirchia, I., Post, T., Duivenvoorden, R., Kluza, E. & Cremers, G. A. O. & 16 others, Kreijtz, J. H. C. M., Pérez-Medina, C., Leent, M. M. T. V., Teunissen, A. J. P., Meel, R. V. D., Zhou, Y., Glass, C., Ochando, J., Joosten, L. A. B., Fayad, Z. A., Netea-Maier, R. T., Netea, M. G., Winther, M. P. J. D., Beldman, T. J., Griffioen, A. W. & Mulder, W. J. M., Jan 2026, In: Science advances. 12, 1, p. 1-16 16 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    3 Scopus citations
  • A cis-regulatory element controls expression of histone deacetylase 9 to fine-tune inflammasome-dependent chronic inflammation in atherosclerosis

    Asare, Y., Yan, G., Schlegl, C., Prestel, M., van der Vorst, E. P. C., Teunissen, A. J. P., Aronova, A., Tosato, F., Naser, N., Caputo, J., Prevot, G., Azzun, A., Wefers, B., Wurst, W., Schneider, M., Forne, I., Bidzhekov, K., Naumann, R., van der Laan, S. W. & Brandhofer, M. & 10 others, Cao, J., Roth, S., Malik, R., Tiedt, S., Mulder, W. J. M., Imhof, A., Liesz, A., Weber, C., Bernhagen, J. & Dichgans, M., 11 Mar 2025, In: Immunity. 58, 3, p. 555-567.e9

    Research output: Contribution to journalArticlepeer-review

    Open Access
    22 Scopus citations
  • C1q reprograms innate immune memory

    Jonkman, I., Jacobs, M. M. E., Negishi, Y., van Heck, J. I. P., Matzaraki, V., Martens, J. H. A., Baltissen, M., Vermeulen, M., Fayad, Z. A., Teunissen, A. J. P., Mulder, W. J. M., Hilbrands, L. B., Joosten, L. A. B., Netea, M. G., Mhlanga, M. M., Rother, N. & Duivenvoorden, R., 2025, In: Frontiers in Immunology. 16, 1515127.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    4 Scopus citations