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PROFESSOR | Psychiatry, PROFESSOR | Neuroscience
Biography
Dr. Haroutunian joined the faculty at The Mount Sinai School of Medicine in the summer of 1982 and is now Professor of Psychiatry and Neurobiology. Dr. Haroutunian came to Mount Sinai after completing a postdoctoral training program at Princeton concentrating on research in development and in aging. His research interests since joining the Mount Sinai faculty have centered on the neurobiology of Alzheimer’s disease and schizophrenia. He directs the Division of Basic and Laboratory Science in the Department of Psychiatry, the Alzheimer’s disease and Schizophrenia Brain Bank, a National Institute of Aging program project grant entitled Clinical and Biological Studies of Early Alzheimer’s disease, a National Institute of Mental Health R01 grant and a Veterans Affairs Merit grant on the roles of glutamate in schizophrenia, and is the Associate Director for Research for the Veterans Administration Mental Illness Research and Education Clinical Center. He is also a major contributor to Mount Sinai’s Silvio Conte Center for Neuroscience and the Alzheimer’s disease Research Center. In the past decade Dr. Haroutunian’s research has centered on clinical and neuropathological correlated of schizophrenia and dementia. He has used molecular biological techniques, including microarray technology (DNA-chip) and neuropathological studies to understand the biological substrates of mental illness and dementia. Dr. Haroutunian works closely with his associates and colleagues Dr. Stella Dracheva and Dr. Pavel Katsel and collaborates with many members of the Department of Psychiatry and researchers at Mount Sinai and multiple other institutions in the US and around the world. These collaborations include studies conducted jointly with Dr. Kenneth Davis, Dr. Joseph Buxbaum, Dr. Giulio Pasinetti, Dr. Gregory Elder and Dr. Philip Harvey. Multi-Disciplinary Training Area Neuroscience [NEU] Education PhD, Kent State University Princeton University
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Collaborations and top research areas from the last five years
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Multi-omic expression of the VEGF family relates to Alzheimer's disease across diverse populations
Libby, J. B., Deters, K. D., Ertekin-Taner, N., Carrasquillo, M. M., Allen, M., De Jager, P., Menon, V., Zhang, B., Haroutunian, V., Levey, A. I., Seyfried, N. T., Kaddurah-Daouk, R., Finkbeiner, S., Wang, D., Greenwood, A. K., Vander Linden, A., Heath, L., Poehlman, W. L., Dumitrescu, L. & Petyuk, V. A. & 4 others, , Jan 2026, In: Alzheimer's and Dementia. 22, 1, e71100.Research output: Contribution to journal › Article › peer-review
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Pan-neurodegeneration proteomics reveals disease subtypes and molecular signatures
Shrestha, H. K., Sun, H., Yarbro, J. M., Lee, D. G., Liu, D., Wang, E., McReynolds, M., Zhang, N., Xie, B., Yang, S., Yu, K., Poudel, S., Li, Y., Yuan, Z. F., Kong, D., Wang, M., Wang, Z., Niu, M., Wang, H. & Zaman, M. & 27 others, , 2026, (Accepted/In press) In: Cell.Research output: Contribution to journal › Article › peer-review
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Sex and APOE genotype specific brain regional vulnerability to Alzheimer's Disease
Members of the Alzheimers Disease Neuroimaging Initiative, 2026, (Accepted/In press) In: GeroScience.Research output: Contribution to journal › Article › peer-review
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Alzheimer’s disease transcriptional landscape in ex vivo human microglia
Kosoy, R., Fullard, J. F., Bendl, J., Kleopoulos, S. P., Shao, Z., Argyriou, S., Mathur, D., Psychogyiou, K., Malakates, P., Vicari, J., Ma, Y., Humphrey, J., Brophy, E., Raj, T., Katsel, P., Voloudakis, G., Lee, D., Bennett, D. A., Haroutunian, V. & Hoffman, G. E. & 1 others, , Sep 2025, In: Nature Neuroscience. 28, 9, p. 1830-1843 14 p.Research output: Contribution to journal › Article › peer-review
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A map of enhancer regions in primary human neural progenitor cells using capture STARR-seq
PsychENCODE Consortium, Aug 2025, In: Genome Research. 35, 8, p. 1887-1901 15 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations
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St. Jude Children's Research Hospital: Protein atlas connects the biologic dots underlying neurodegenerative diseases
23/03/26
3 items of Media coverage
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Researchers' Work from Icahn School of Medicine at Mount Sinai Focuses on Mental Health Diseases and Conditions (Population-scale cross-disorder atlas of the human prefrontal cortex at single-cell resolution)
Venkatesh, S., Voloudakis, G., Haroutunian, V., Roussos, P., Fullard, J., Lee, D., Girdhar, K. & Hoffman, G.
23/06/25
1 item of Media coverage
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New Genetic Risk Study Findings Have Been Reported by Investigators at Icahn School of Medicine at Mount Sinai (Long-read Rna Sequencing Atlas of Human Microglia Isoforms Elucidates Disease-associated Genetic Regulation of Splicing)
Zeng, B., Sebra, R., Raj, T., Haroutunian, V., Roussos, P., Fullard, J., De Witte, L., Hoffman, G. & Goate, A.
9/04/25
1 item of Media coverage
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