Tim Ahfeldt

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ASSISTANT PROFESSOR | Neuroscience ASSISTANT PROFESSOR | Neurology

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Understanding cell-type vulnerability and oxidative stress pathology in Parkinson's Disease using isogenic human dopaminergic neurons
Blanchard, J. J. W. & Ahfeldt, T.
National Institute of Neurological Disorders and Stroke
1/09/20 → 31/08/23
Project: Research

19 Article
2 Review article
1 Comment/debate

A reference human induced pluripotent stem cell line for large-scale collaborative studies
Pantazis, C. B., Yang, A., Lara, E., McDonough, J. A., Blauwendraat, C., Peng, L., Oguro, H., Kanaujiya, J., Zou, J., Sebesta, D., Pratt, G., Cross, E., Blockwick, J., Buxton, P., Kinner-Bibeau, L., Medura, C., Tompkins, C., Hughes, S., Santiana, M., Faghri, F., & 75 othersNalls, M. A., Vitale, D., Ballard, S., Qi, Y. A., Ramos, D. M., Anderson, K. M., Stadler, J., Narayan, P., Papademetriou, J., Reilly, L., Nelson, M. P., Aggarwal, S., Rosen, L. U., Kirwan, P., Pisupati, V., Coon, S. L., Scholz, S. W., Priebe, T., Öttl, M., Dong, J., Meijer, M., Janssen, L. J. M., Lourenco, V. S., van der Kant, R., Crusius, D., Paquet, D., Raulin, A. C., Bu, G., Held, A., Wainger, B. J., Gabriele, R. M. C., Casey, J. M., Wray, S., Abu-Bonsrah, D., Parish, C. L., Beccari, M. S., Cleveland, D. W., Li, E., Rose, I. V. L., Kampmann, M., Calatayud Aristoy, C., Verstreken, P., Heinrich, L., Chen, M. Y., Schüle, B., Dou, D., Holzbaur, E. L. F., Zanellati, M. C., Basundra, R., Deshmukh, M., Cohen, S., Khanna, R., Raman, M., Nevin, Z. S., Matia, M., Van Lent, J., Timmerman, V., Conklin, B. R., Johnson Chase, K., Zhang, K., Funes, S., Bosco, D. A., Erlebach, L., Welzer, M., Kronenberg-Versteeg, D., Lyu, G., Arenas, E., Coccia, E., Sarrafha, L., Ahfeldt, T., Marioni, J. C., Skarnes, W. C., Cookson, M. R., Ward, M. E. & Merkle, F. T., 1 Dec 2022, In: Cell Stem Cell. 29, 12, p. 1685-1702.e22
Research output: Contribution to journal › Article › peer-review

Open Access
1 Scopus citations
Dysregulation of mitochondrial and proteolysosomal genes in Parkinson’s disease myeloid cells
Navarro, E., Udine, E., Lopes, K. D. P., Parks, M., Riboldi, G., Schilder, B. M., Humphrey, J., Snijders, G. J. L., Vialle, R. A., Zhuang, M., Sikder, T., Argyrou, C., Allan, A., Chao, M. J., Farrell, K., Henderson, B., Simon, S., Raymond, D., Elango, S., Ortega, R. A., & 16 othersShanker, V., Swan, M., Zhu, C. W., Ramdhani, R., Walker, R. H., Tse, W., Sano, M., Pereira, A. C., Ahfeldt, T., Goate, A. M., Bressman, S., Crary, J. F., de Witte, L., Frucht, S., Saunders-Pullman, R. & Raj, T., Sep 2021, In: Nature Aging. 1, 9, p. 850-863 14 p.
Research output: Contribution to journal › Article › peer-review
5 Scopus citations
High-throughput generation of midbrain dopaminergic neuron organoids from reporter human pluripotent stem cells
Sarrafha, L., Parfitt, G. M., Reyes, R., Goldman, C., Coccia, E., Kareva, T. & Ahfeldt, T., 18 Jun 2021, In: STAR Protocols. 2, 2, 100463.
Research output: Contribution to journal › Article › peer-review

Open Access
4 Scopus citations
Temporal proteomics during neurogenesis reveals large-scale proteome and organelle remodeling via selective autophagy
Ordureau, A., Kraus, F., Zhang, J., An, H., Park, S., Ahfeldt, T., Paulo, J. A. & Harper, J. W., 16 Dec 2021, In: Molecular Cell. 81, 24, p. 5082-5098.e11
Research output: Contribution to journal › Article › peer-review

Open Access
16 Scopus citations
Towards physiologically relevant human pluripotent stem cell (hPSC) models of Parkinson’s disease
Coccia, E. & Ahfeldt, T., Dec 2021, In: Stem Cell Research and Therapy. 12, 1, 253.
Research output: Contribution to journal › Review article › peer-review

Open Access
7 Scopus citations

Recursion Provides Business Updates and Reports Fourth Quarter and Fiscal Year 2021 Financial Results'
Tim Ahfeldt
23/03/22
1 item of Media coverage
Press/Media
Recursion Provides Business Updates and Reports Fourth Quarter and Fiscal Year 2021 Financial Results
Tim Ahfeldt
23/03/22
53 items of Media coverage
Press/Media
Industry Briefs
Tim Ahfeldt
13/12/21
1 item of Media coverage
Press/Media
Industry Briefs 12-12-21
Tim Ahfeldt
11/12/21
1 item of Media coverage
Press/Media
Roche, Genentech, Recursion Launch Up-to-$12B AI Drug Discovery Effort
Tim Ahfeldt
7/12/21
1 item of Media coverage
Press/Media

Tim Ahfeldt

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Understanding cell-type vulnerability and oxidative stress pathology in Parkinson's Disease using isogenic human dopaminergic neurons

A reference human induced pluripotent stem cell line for large-scale collaborative studies

Dysregulation of mitochondrial and proteolysosomal genes in Parkinson’s disease myeloid cells

High-throughput generation of midbrain dopaminergic neuron organoids from reporter human pluripotent stem cells

Temporal proteomics during neurogenesis reveals large-scale proteome and organelle remodeling via selective autophagy

Towards physiologically relevant human pluripotent stem cell (hPSC) models of Parkinson’s disease

Recursion Provides Business Updates and Reports Fourth Quarter and Fiscal Year 2021 Financial Results'

Recursion Provides Business Updates and Reports Fourth Quarter and Fiscal Year 2021 Financial Results

Industry Briefs

Industry Briefs 12-12-21

Roche, Genentech, Recursion Launch Up-to-$12B AI Drug Discovery Effort

Tim Ahfeldt

Personal profile

Headline

Fingerprint

Network

Projects

Research output

Press/Media