Research output per year
Research output per year
Personal profile
Headline
ASSISTANT PROFESSOR | Medicine, Hematology and Medical Oncology, ASSISTANT PROFESSOR | Cell, Developmental and Regenerative Biology, ASSISTANT PROFESSOR | Oncological Sciences
Biography
Research Topics Anti-Tumor Therapy, Apoptosis/Cell Death, Cancer Genetics, Cell Biology, Cell Cycle, DNA Repair, Drug Design and Discovery, Drug Resistance, Oncogenes, Signal Transduction, Tumor Suppressor Genes Multi-Disciplinary Training Areas Cancer Biology [CAB], Developmental and Stem Cell Biology [DSCB], Genetics and Genomic Sciences [GGS] Education BS/MS, Paris VII University Instructor, Harvard Medical School MS, Paris VI University PhD, Max-Planck Institute for Developmental Biology, University of Tubingen, and Paris VI University Postdoctoral fellowship, Dana-Farber Cancer Institute, Harvard Medical School Language English Awards 2012 Young Scientist Cancer Research Award 2011 Searle Scholar 2009 Claudia Adams Barr Award in Cancer Research 2004 French Foundation for Medical Research (FRM) Scholarship 2003 French Association for Cancer Research (ARC) Scholarship
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Collaborations and top research areas from the last five years
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Stepwise phosphorylation and SUMOylation of PIDD1 drive PIDDosome assembly in response to DNA repair failure
Shah, R. B., Li, Y., Yu, H., Kini, E. & Sidi, S., Dec 2024, In: Nature Communications. 15, 1, 9195.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
A noncanonical IRAK4-IRAK1 pathway counters DNA damage–induced apoptosis independently of TLR/IL-1R signaling
Li, Y., Shah, R. B., Sarti, S., Belcher, A. L., Lee, B. J., Gorbatenko, A., Nemati, F., Yu, H., Stanley, Z., Rahman, M., Shao, Z., Silva, J. M., Zha, S. & Sidi, S., 2023, In: Science Signaling. 16, 816Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
FANCI functions as a repair/apoptosis switch in response to DNA crosslinks
Shah, R. B., Kernan, J. L., van Hoogstraten, A., Ando, K., Li, Y., Belcher, A. L., Mininger, I., Bussenault, A. M., Raman, R., Ramanagoudr-Bhojappa, R., Huang, T. T., D'Andrea, A. D., Chandrasekharappa, S. C., Aggarwal, A. K., Thompson, R. & Sidi, S., 9 Aug 2021, In: Developmental Cell. 56, 15, p. 2207-2222.e7Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
Sulfopin is a covalent inhibitor of Pin1 that blocks Myc-driven tumors in vivo
Dubiella, C., Pinch, B. J., Koikawa, K., Zaidman, D., Poon, E., Manz, T. D., Nabet, B., He, S., Resnick, E., Rogel, A., Langer, E. M., Daniel, C. J., Seo, H. S., Chen, Y., Adelmant, G., Sharifzadeh, S., Ficarro, S. B., Jamin, Y., Martins da Costa, B. & Zimmerman, M. W. & 24 others, , Sep 2021, In: Nature Chemical Biology. 17, 9, p. 954-963 10 p.Research output: Contribution to journal › Article › peer-review
Open Access108 Scopus citations -
An IRAK1–PIN1 signalling axis drives intrinsic tumour resistance to radiation therapy
Liu, P. H., Shah, R. B., Li, Y., Arora, A., Ung, P. M. U., Raman, R., Gorbatenko, A., Kozono, S., Zhou, X. Z., Brechin, V., Barbaro, J. M., Thompson, R., White, R. M., Aguirre-Ghiso, J. A., Heymach, J. V., Lu, K. P., Silva, J. M., Panageas, K. S., Schlessinger, A. & Maki, R. G. & 3 others, , 1 Feb 2019, In: Nature Cell Biology. 21, 2, p. 203-213 11 p.Research output: Contribution to journal › Article › peer-review
Open Access44 Scopus citations
Press/Media
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New Science Findings from Icahn School of Medicine at Mount Sinai Outlined (A Noncanonical Irak4-irak1 Pathway Counters Dna Damage-induced Apoptosis Independently of Tlr/il-1r Signaling)
Sidi, S., Li, Y., Silva, J. & Shah, B.
5/04/24
1 item of Media coverage
Press/Media