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Samuel Sidi

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Samuel Sidi

PhD

20022026

Research activity per year

Personal profile

Headline

ASSISTANT PROFESSOR | Medicine, Hematology and Medical Oncology, ASSISTANT PROFESSOR | Cell, Developmental and Regenerative Biology, ASSISTANT PROFESSOR | Oncological Sciences

Biography

Research Topics Anti-Tumor Therapy, Apoptosis/Cell Death, Cancer Genetics, Cell Biology, Cell Cycle, DNA Repair, Drug Design and Discovery, Drug Resistance, Oncogenes, Signal Transduction, Tumor Suppressor Genes Multi-Disciplinary Training Areas Cancer Biology [CAB], Developmental and Stem Cell Biology [DSCB], Genetics and Genomic Sciences [GGS] Education BS/MS, Paris VII University Instructor, Harvard Medical School MS, Paris VI University PhD, Max-Planck Institute for Developmental Biology, University of Tubingen, and Paris VI University Postdoctoral fellowship, Dana-Farber Cancer Institute, Harvard Medical School Language English Awards 2012 Young Scientist Cancer Research Award 2011 Searle Scholar 2009 Claudia Adams Barr Award in Cancer Research 2004 French Foundation for Medical Research (FRM) Scholarship 2003 French Association for Cancer Research (ARC) Scholarship

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  • PARP4 ADP-ribosylates PIDD1 to complete a phospho/SUMO/PAR-ylation cascade that orchestrates PIDDosome assembly

    Shah, R. B., Li, Y., Person, A., Frigon, L., Đukić, N., Kini, E., Chen, R., Pascal, J. M., Cohen, M. S., Ahel, I., Haley, J. D. & Sidi, S., Jan 2026, In: Science advances. 12, 18, eadz9284.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • Stepwise phosphorylation and SUMOylation of PIDD1 drive PIDDosome assembly in response to DNA repair failure

    Shah, R. B., Li, Y., Yu, H., Kini, E. & Sidi, S., Dec 2024, In: Nature Communications. 15, 1, 9195.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    8 Scopus citations

  • A noncanonical IRAK4-IRAK1 pathway counters DNA damage–induced apoptosis independently of TLR/IL-1R signaling

    Li, Y., Shah, R. B., Sarti, S., Belcher, A. L., Lee, B. J., Gorbatenko, A., Nemati, F., Yu, H., Stanley, Z., Rahman, M., Shao, Z., Silva, J. M., Zha, S. & Sidi, S., 2023, In: Science Signaling. 16, 816

    Research output: Contribution to journal › Article › peer-review

    Open Access
    13 Scopus citations

  • FANCI functions as a repair/apoptosis switch in response to DNA crosslinks

    Shah, R. B., Kernan, J. L., van Hoogstraten, A., Ando, K., Li, Y., Belcher, A. L., Mininger, I., Bussenault, A. M., Raman, R., Ramanagoudr-Bhojappa, R., Huang, T. T., D'Andrea, A. D., Chandrasekharappa, S. C., Aggarwal, A. K., Thompson, R. & Sidi, S., 9 Aug 2021, In: Developmental Cell. 56, 15, p. 2207-2222.e7

    Research output: Contribution to journal › Article › peer-review

    Open Access
    16 Scopus citations

  • Sulfopin is a covalent inhibitor of Pin1 that blocks Myc-driven tumors in vivo

    Dubiella, C., Pinch, B. J., Koikawa, K., Zaidman, D., Poon, E., Manz, T. D., Nabet, B., He, S., Resnick, E., Rogel, A., Langer, E. M., Daniel, C. J., Seo, H. S., Chen, Y., Adelmant, G., Sharifzadeh, S., Ficarro, S. B., Jamin, Y., Martins da Costa, B. & Zimmerman, M. W. & 24 others, Lian, X., Kibe, S., Kozono, S., Doctor, Z. M., Browne, C. M., Yang, A., Stoler-Barak, L., Shah, R. B., Vangos, N. E., Geffken, E. A., Oren, R., Koide, E., Sidi, S., Shulman, Z., Wang, C., Marto, J. A., Dhe-Paganon, S., Look, T., Zhou, X. Z., Lu, K. P., Sears, R. C., Chesler, L., Gray, N. S. & London, N., Sep 2021, In: Nature Chemical Biology. 17, 9, p. 954-963 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    125 Scopus citations
View all 31 Research outputs