Sacha Gnjatic

2023

A methylation clock model of mild SARS-CoV-2 infection provides insight into immune dysregulation

Biobank Team, 2023, (Accepted/In press) In: Molecular Systems Biology.

Research output: Contribution to journal › Article › peer-review

Open Access

Anti-Integrin αvβ6 Autoantibodies Are a Novel Biomarker That Antedate Ulcerative Colitis

CCC-GEM Project Research Consortium & OSCCAR Consortium, Apr 2023, In: Gastroenterology. 164, 4, p. 619-629 11 p.

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Autoimmunity in Down’s syndrome via cytokines, CD4 T cells and CD11c⁺ B cells

Malle, L., Patel, R. S., Martin-Fernandez, M., Stewart, O. J., Philippot, Q., Buta, S., Richardson, A., Barcessat, V., Taft, J., Bastard, P., Samuels, J., Mircher, C., Rebillat, A. S., Maillebouis, L., Vilaire-Meunier, M., Tuballes, K., Rosenberg, B. R., Trachtman, R., Casanova, J. L., Notarangelo, L. D., & 3 othersGnjatic, S., Bush, D. & Bogunovic, D., 9 Mar 2023, In: Nature. 615, 7951, p. 305-314 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

Circulating proteins to predict COVID-19 severity

Dec 2023, In: Scientific Reports. 13, 1, 6236.

Research output: Contribution to journal › Article › peer-review

Open Access

Cross center single-cell RNA sequencing study of the immune microenvironment in rapid progressing multiple myeloma

Pilcher, W., Thomas, B. E., Bhasin, S. S., Jayasinghe, R. G., Yao, L., Gonzalez-Kozlova, E., Dasari, S., Kim-Schulze, S., Rahman, A., Patton, J., Fiala, M., Cheloni, G., Kourelis, T., Dhodapkar, M. V., Vij, R., Mehr, S., Hamilton, M., Cho, H. J., Auclair, D., Avigan, D. E., & 4 othersKumar, S. K., Gnjatic, S., Ding, L. & Bhasin, M., Dec 2023, In: npj Genomic Medicine. 8, 1, 3.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

Erratum: Mapping Systemic Inflammation and Antibody Responses in Multisystem Inflammatory Syndrome in Children (MIS-C) (Cell (2020) 183(4) (982–995.e14), (S0092867420312319), (10.1016/j.cell.2020.09.034))

Gruber, C. N., Patel, R. S., Trachtman, R., Lepow, L., Amanat, F., Krammer, F., Wilson, K. M., Onel, K., Geanon, D., Tuballes, K., Patel, M., Mouskas, K., O'Donnell, T., Merritt, E., Simons, N. W., Barcessat, V., Del Valle, D. M., Udondem, S., Kang, G., Agashe, C., & 16 othersKarekar, N., Grabowska, J., Nie, K., Le Berichel, J., Xie, H., Beckmann, N., Gangadharan, S., Ofori-Amanfo, G., Laserson, U., Rahman, A., Kim-Schulze, S., Charney, A. W., Gnjatic, S., Gelb, B. D., Merad, M. & Bogunovic, D., 20 Jul 2023, In: Cell. 186, 15, p. 3325 1 p.

Research output: Contribution to journal › Comment/debate

Open Access

Evaluation of immunological responses to third COVID-19 vaccine among people treated with sphingosine receptor-1 modulators and anti-CD20 therapy

Katz Sand, I., Gnjatic, S., Krammer, F., Tuballes, K., Carreño, J. M., Satyanarayan, S., Filomena, S., Staker, E., Tcheou, J., Miller, A., Fabian, M., Safi, N., Nichols, J., Patel, J., Krieger, S., Tankou, S., Horng, S., Klineova, S., Beck, E., Merad, M., & 1 othersLublin, F., Feb 2023, In: Multiple Sclerosis and Related Disorders. 70, 104486.

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Germline rare deleterious variant load alters cancer risk, age of onset and tumor characteristics

Esai Selvan, M., Onel, K., Gnjatic, S., Klein, R. J. & Gümüş, Z. H., Dec 2023, In: npj Precision Oncology. 7, 1, 13.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

IgG memory B cells expressing IL4R and FCER2 are associated with atopic diseases

Aranda, C. J., Gnjatic, S. & Curotto de Lafaille, M. A., Mar 2023, In: Allergy: European Journal of Allergy and Clinical Immunology. 78, 3, p. 752-766 15 p.

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Intratumoral dendritic cell–CD4⁺ T helper cell niches enable CD8⁺ T cell differentiation following PD-1 blockade in hepatocellular carcinoma

Magen, A., Hamon, P., Fiaschi, N., Soong, B. Y., Park, M. D., Mattiuz, R., Humblin, E., Troncoso, L., D’souza, D., Dawson, T., Kim, J., Hamel, S., Buckup, M., Chang, C., Tabachnikova, A., Schwartz, H., Malissen, N., Lavin, Y., Soares-Schanoski, A., Giotti, B., & 33 othersHegde, S., Ioannou, G., Gonzalez-Kozlova, E., Hennequin, C., Le Berichel, J., Zhao, Z., Ward, S. C., Fiel, I., Kou, B., Dobosz, M., Li, L., Adler, C., Ni, M., Wei, Y., Wang, W., Atwal, G. S., Kundu, K., Cygan, K. J., Tsankov, A. M., Rahman, A., Price, C., Fernandez, N., He, J., Gupta, N. T., Kim-Schulze, S., Gnjatic, S., Kenigsberg, E., Deering, R. P., Schwartz, M., Marron, T. U., Thurston, G., Kamphorst, A. O. & Merad, M., Jun 2023, In: Nature Medicine. 29, 6, p. 1389-1399 11 p.

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Mechanisms of response and resistance to combined decitabine and ipilimumab for advanced myeloid disease

Penter, L., Liu, Y., Wolff, J. O., Yang, L., Taing, L., Jhaveri, A., Southard, J., Patel, M., Cullen, N. M., Pfaff, K. L., Cieri, N., Oliveira, G., Kim-Schulze, S., Ranasinghe, S., Leonard, R., Robertson, T., Morgan, E. A., Chen, H. X., Song, M. H., Thurin, M., & 17 othersLi, S., Rodig, S. J., Cibulskis, C., Gabriel, S., Bachireddy, P., Ritz, J., Streicher, H., Neuberg, D. S., Hodi, F. S., Davids, M. S., Gnjatic, S., Livak, K. J., Altreuter, J., Michor, F., Soiffer, R. J., Garcia, J. S. & Wu, C. J., 13 Apr 2023, In: Blood. 141, 15, p. 1817-1830 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

Molecular states during acute COVID-19 reveal distinct etiologies of long-term sequelae

The Mount Sinai COVID-19 Biobank Team, 1 Jan 2023, In: Nature Medicine. 29, 1, p. 236-246 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

Phase I Study of a Multivalent WT1 Peptide Vaccine (Galinpepimut-S) in Combination with Nivolumab in Patients with WT1-Expressing Ovarian Cancer in Second or Third Remission

Manning-Geist, B. L., Gnjatic, S., Aghajanian, C., Konner, J., Kim, S. H., Sarasohn, D., Soldan, K., Tew, W. P., Sarlis, N. J., Zamarin, D., Kravetz, S., Laface, I., Rasalan-Ho, T., Qi, J., Wong, P., Sabbatini, P. J. & O’Cearbhaill, R. E., Mar 2023, In: Cancers. 15, 5, 1458.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

2022

A shift in lung macrophage composition is associated with COVID-19 severity and recovery

Chen, S. T., Park, M. D., Del Valle, D. M., Buckup, M., Tabachnikova, A., Thompson, R. C., Simons, N. W., Mouskas, K., Lee, B., Geanon, D., D'Souza, D., Dawson, T., Marvin, R., Nie, K., Zhao, Z., LeBerichel, J., Chang, C., Jamal, H., Akturk, G., Chaddha, U., & 16 othersMathews, K., Acquah, S., Brown, S. A., Reiss, M., Harkin, T., Feldmann, M., Powell, C. A., Hook, J. L., Kim-Schulze, S., Rahman, A. H., Brown, B. D., Beckmann, N. D., Gnjatic, S., Kenigsberg, E., Charney, A. W. & Merad, M., 14 Sep 2022, In: Science Translational Medicine. 14, 662, abn5168.

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Author Correction: Neoadjuvant clinical trials provide a window of opportunity for cancer drug discovery (Nature Medicine, (2022), 28, 4, (626-629), 10.1038/s41591-022-01681-x)

Marron, T. U., Galsky, M. D., Taouli, B., Fiel, M. I., Ward, S., Kim, E., Yankelevitz, D., Doroshow, D., Guttman-Yassky, E., Ungar, B., Mehandru, S., Golas, B. J., Labow, D., Sfakianos, J., Nair, S. S., Chakravarty, D., Buckstein, M., Song, X., Kenigsberg, E., Gnjatic, S., & 6 othersBrown, B. D., Sparano, J., Tewari, A., Schwartz, M., Bhardwaj, N. & Merad, M., Aug 2022, In: Nature Medicine. 28, 8, p. 1723 1 p.

Research output: Contribution to journal › Comment/debate

Open Access

Cancer vaccines

Schiller, J. T., Lowy, D. R., Frazer, I. H., Finn, O. J., Vilar, E., Lyerly, H. K., Gnjatic, S., Zaidi, N., Ott, P. A., Balachandran, V. P., Dietrich, P. Y., Migliorini, D., Vonderheide, R. H. & Domchek, S. M., 13 Jun 2022, In: Cancer Cell. 40, 6, p. 559-564 6 p.

Research output: Contribution to journal › Comment/debate

Open Access

11 Scopus citations

Correction: The dynamic changes and sex differences of 147 immune-related proteins during acute COVID-19 in 580 individuals (Clinical Proteomics, (2022), 19, 1, (34), 10.1186/s12014-022-09371-z)

The Mount Sinai COVID-19 Biobank Team, Dec 2022, In: Clinical Proteomics. 19, 1, 40.

Research output: Contribution to journal › Comment/debate

Open Access

Early non-neutralizing, afucosylated antibody responses are associated with COVID-19 severity

Chakraborty, S., Gonzalez, J. C., Sievers, B. L., Mallajosyula, V., Chakraborty, S., Dubey, M., Ashraf, U., Cheng, B. Y. L., Kathale, N., Tran, K. Q. T., Scallan, C., Sinnott, A., Cassidy, A., Chen, S. T., Gelbart, T., Gao, F., Golan, Y., Ji, X., Kim-Schulze, S., Prahl, M., & 22 othersGaw, S. L., Gnjatic, S., Marron, T. U., Merad, M., Arunachalam, P. S., Boyd, S. D., Davis, M. M., Holubar, M., Khosla, C., Maecker, H. T., Maldonado, Y., Mellins, E. D., Nadeau, K. C., Pulendran, B., Singh, U., Subramanian, A., Utz, P. J., Sherwood, R., Zhang, S., Jagannathan, P., Tan, G. S. & Wang, T. T., 9 Mar 2022, In: Science Translational Medicine. 14, 635, abm7853.

Research output: Contribution to journal › Article › peer-review

46 Scopus citations

Exome-wide association study to identify rare variants influencing COVID-19 outcomes: Results from the Host Genetics Initiative

Butler-Laporte, G., Povysil, G., Kosmicki, J. A., Cirulli, E. T., Drivas, T., Furini, S., Saad, C., Schmidt, A., Olszewski, P., Korotko, U., Quinodoz, M., Çelik, E., Kundu, K., Walter, K., Jung, J., Stockwell, A. D., Sloofman, L. G., Jordan, D. M., Thompson, R. C., Del Valle, D., & 139 othersSimons, N., Cheng, E., Sebra, R., Schadt, E. E., Kim-Schulze, S., Gnjatic, S., Merad, M., Buxbaum, J. D., Beckmann, N. D., Charney, A. W., Przychodzen, B., Chang, T., Pottinger, T. D., Shang, N., Brand, F., Fava, F., Mari, F., Chwialkowska, K., Niemira, M., Pula, S., Kenneth Baillie, J., Stuckey, A., Salas, A., Bello, X., Pardo-Seco, J., Gómez-Carballa, A., Rivero-Calle, I., Martinón-Torres, F., Ganna, A., Karczewski, K. J., Veerapen, K., Bourgey, M., Bourque, G., Eveleigh, R. J. M., Forgetta, V., Morrison, D., Langlais, D., Lathrop, M., Mooser, V., Nakanishi, T., Frithiof, R., Hultström, M., Lipcsey, M., Marincevic-Zuniga, Y., Nordlund, J., Schiabor Barrett, K. M., Lee, W., Bolze, A., White, S., Riffle, S., Tanudjaja, F., Sandoval, E., Neveux, I., Dabe, S., Casadei, N., Motameny, S., Alaamery, M., Massadeh, S., Aljawini, N., Almutairi, M. S., Arabi, Y. M., Alqahtani, S. A., Al Harthi, F. S., Almutairi, A., Alqubaishi, F., Alotaibi, S., Binowayn, A., Alsolm, E. A., Bardisy, H. E., Fawzy, M., Cai, F., Soranzo, N., Butterworth, A., Center, R. G., Geschwind, D. H., Arteaga, S., Stephens, A., Butte, M. J., Boutros, P. C., Yamaguchi, T. N., Tao, S., Eng, S., Sanders, T., Tung, P. J., Broudy, M. E., Pan, Y., Gonzalez, A., Chavan, N., Johnson, R., Pasaniuc, B., Yaspan, B., Smieszek, S., Rivolta, C., Bibert, S., Bochud, P. Y., Dabrowski, M., Zawadzki, P., Sypniewski, M., Kaja, E., Chariyavilaskul, P., Nilaratanakul, V., Hirankarn, N., Shotelersuk, V., Pongpanich, M., Phokaew, C., Chetruengchai, W., Tokunaga, K., Sugiyama, M., Kawai, Y., Hasegawa, T., Naito, T., Namkoong, H., Edahiro, R., Kimura, A., Ogawa, S., Kanai, T., Fukunaga, K., Okada, Y., Imoto, S., Miyano, S., Mangul, S., Abedalthagafi, M. S., Zeberg, H., Grzymski, J. J., Washington, N. L., Ossowski, S., Ludwig, K. U., Schulte, E. C., Riess, O., Moniuszko, M., Kwasniewski, M., Mbarek, H., Ismail, S. I., Verma, A., Goldstein, D. B., Kiryluk, K., Renieri, A., Ferreira, M. A. R. & Brent Richards, J., 3 Nov 2022, In: PLoS Genetics. 18, 11, e1010367.

Research output: Contribution to journal › Article › peer-review

Open Access

14 Scopus citations

High Dimensional Immune Profiling of Smoldering Multiple Myeloma Distinguishes Distinct Tumor Microenvironments

Fernandez, N., Perumal, D., Rahman, A., Kim-Schulze, S., Yesil, J., Auclair, D., Adams, H., Parekh, S., Gnjatic, S. & Cho, H. J., Nov 2022, In: Clinical Lymphoma, Myeloma and Leukemia. 22, 11, p. 853-862 10 p.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Neoadjuvant cemiplimab for resectable hepatocellular carcinoma: a single-arm, open-label, phase 2 trial

Marron, T. U., Fiel, M. I., Hamon, P., Fiaschi, N., Kim, E., Ward, S. C., Zhao, Z., Kim, J., Kennedy, P., Gunasekaran, G., Tabrizian, P., Doroshow, D., Legg, M., Hammad, A., Magen, A., Kamphorst, A. O., Shareef, M., Gupta, N. T., Deering, R., Wang, W., & 33 othersWang, F., Thanigaimani, P., Mani, J., Troncoso, L., Tabachnikova, A., Chang, C., Akturk, G., Buckup, M., Hamel, S., Ioannou, G., Hennequin, C., Jamal, H., Brown, H., Bonaccorso, A., Labow, D., Sarpel, U., Rosenbloom, T., Sung, M. W., Kou, B., Li, S., Jankovic, V., James, N., Hamon, S. C., Cheung, H. K., Sims, J. S., Miller, E., Bhardwaj, N., Thurston, G., Lowy, I., Gnjatic, S., Taouli, B., Schwartz, M. E. & Merad, M., Mar 2022, In: The Lancet Gastroenterology and Hepatology. 7, 3, p. 219-229 11 p.

Research output: Contribution to journal › Article › peer-review

51 Scopus citations

Neoadjuvant clinical trials provide a window of opportunity for cancer drug discovery

Marron, T. U., Galsky, M. D., Taouli, B., Fiel, M. I., Ward, S., Kim, E., Yankelevitz, D., Doroshow, D., Guttman, E., Ungar, B., Mehandru, S., Golas, B. J., Labow, D., Sfakianos, J., Nair, S. S., Chakravarty, D., Buckstein, M., Song, X., Kenigsberg, E., Gnjatic, S., & 6 othersBrown, B. D., Sparano, J., Tewari, A., Schwartz, M., Bhardwaj, N. & Merad, M., Apr 2022, In: Nature Medicine. 28, 4, p. 626-629 4 p.

Research output: Contribution to journal › Comment/debate

8 Scopus citations

Neutralizing Anti-Granulocyte Macrophage-Colony Stimulating Factor Autoantibodies Recognize Post-Translational Glycosylations on Granulocyte Macrophage-Colony Stimulating Factor Years Before Diagnosis and Predict Complicated Crohn's Disease

Chuang, L. S., Petralia, F., Rahman, A., Kenigsberg, E., Merad, M., Colombel, J. F. & Gnjatic, S., Sep 2022, In: Gastroenterology. 163, 3, p. 659-670 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

Quantitative chest computed tomography combined with plasma cytokines predict outcomes in COVID-19 patients

Carbonell, G., Del Valle, D. M., Gonzalez-Kozlova, E., Marinelli, B., Klein, E., El Homsi, M., Stocker, D., Chung, M., Bernheim, A., Simons, N. W., Xiang, J., Nirenberg, S., Kovatch, P., Lewis, S., Merad, M., Gnjatic, S. & Taouli, B., Aug 2022, In: Heliyon. 8, 8, e10166.

Research output: Contribution to journal › Article › peer-review

Open Access

Rapid, scalable assessment of SARS-CoV-2 cellular immunity by whole-blood PCR

Schwarz, M., Torre, D., Lozano-Ojalvo, D., Ho, J. S. Y., Marsiglia, W. M., Dar, A. C., Berin, C., Nie, K., Patel, M., Gnjatic, S., Harris, J., Sebra, R., Merad, M., Krammer, F., Kim-schulze, S., Marazzi, I., Ochando, J. & Guccione, E., Nov 2022, In: Nature Biotechnology. 40, 11, p. 1680-1689 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

17 Scopus citations

Spatial CRISPR genomics identifies regulators of the tumor microenvironment

Dhainaut, M., Rose, S. A., Wroblewska, A., Nielsen, S. R., Roudko, V., Pia, L., Wilk, C. M., Lee, B. H., Bhardwaj, N., Rahman, A. H., Baccarini, A., Gnjatic, S., Merad, M. & Brown, B. D., 31 Mar 2022, In: Cell. 185, 7, p. 1223-1239.e20

Research output: Contribution to journal › Article › peer-review

Open Access

49 Scopus citations

Spatial Positioning and Matrix Programs of Cancer-Associated Fibroblasts Promote T-cell Exclusion in Human Lung Tumors

Grout, J. A., Tung, N., Casanova-Acebes, M., Rahman, A. H., Gnjatic, S., Martin, J. C., Wolf, A., Flores, R. M., Beasley, M. B., Marron, T. U., Merad, M., Kenigsberg, E. & Salmon, H., 1 Nov 2022, In: Cancer Discovery. 12, 11, p. 2606-2625 20 p.

Research output: Contribution to journal › Article › peer-review

Open Access

36 Scopus citations

The dynamic changes and sex differences of 147 immune-related proteins during acute COVID-19 in 580 individuals

The Mount Sinai COVID-19 Biobank Team, Dec 2022, In: Clinical Proteomics. 19, 1, 34.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

2021

A randomized trial of combined PD-L1 and CTLA-4 inhibition with targeted low-dose or hypofractionated radiation for patients with metastatic colorectal cancer

Monjazeb, A. M., Giobbie-Hurder, A., Lako, A., Thrash, E. M., Brennick, R. C., Kao, K. Z., Manuszak, C., Gentzler, R. D., Tesfaye, A., Jabbour, S. K., Alese, O. B., Rahma, O. E., Cleary, J. M., Sharon, E., Mamon, H. J., Cho, M., Streicher, H., Chen, H. X., Ahmed, M. M., Mariño-Enríquez, A., & 14 othersKim-Schulze, S., Gnjatic, S., Maverakis, E., Marusina, A. I., Merleev, A. A., Severgnini, M., Pfaff, K. L., Lindsay, J., Weirather, J. L., Ranasinghe, S., Spektor, A., Rodig, S. J., Hodi, S. F. & Schoenfeld, J. D., 1 May 2021, In: Clinical Cancer Research. 27, 9, p. 2470-2480 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

39 Scopus citations

A streamlined whole blood CyTOF workflow defines a circulating immune cell signature of COVID-19

Geanon, D., Lee, B., Gonzalez-Kozlova, E., Kelly, G., Handler, D., Upadhyaya, B., Leech, J., De Real, R. M., Herbinet, M., Magen, A., Del Valle, D., Charney, A., Kim-Schulze, S., Gnjatic, S., Merad, M. & Rahman, A. H., May 2021, In: Cytometry. Part A : the journal of the International Society for Analytical Cytology. 99, 5, p. 446-461 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

16 Scopus citations

Author Correction: Sampling the host response to SARS-CoV-2 in hospitals under siege (Nature Medicine, (2020), 26, 8, (1157-1158), 10.1038/s41591-020-1004-3)

The Mount Sinai COVID-19 Biobank Team, Mar 2021, In: Nature Medicine. 27, 3, p. 560 1 p.

Research output: Contribution to journal › Comment/debate

Open Access

BRAF ^V600E-induced senescence drives Langerhans cell histiocytosis pathophysiology

Bigenwald, C., Wilk, C. M., Casanova-Acebes, M., Jobson, J., Karoulia, Z., Martin, J. C., Grout, J., Baccarini, A., Poulikakos, P. I., Brown, B. D., Gnjatic, S., Lujambio, A. & Merad, M., May 2021, In: Nature Medicine. 27, 5, p. 851-861 11 p.

Research output: Contribution to journal › Article › peer-review

28 Scopus citations

Butanol Purified Food Allergy Herbal Formula-2 Has an Immunomodulating Effect ex-vivo in Pediatric Crohn's Disease Subjects

Chen, X., Lai, J., Song, Y., Yang, N., Gnjatic, S., Gillespie, V., Hahn, W., Chefitz, E., Pittman, N., Jossen, J., Benkov, K., Dubinsky, M., Li, X. M. & Dunkin, D., 29 Nov 2021, In: Frontiers in Medicine. 8, 782859.

Research output: Contribution to journal › Article › peer-review

Open Access

Downregulation of exhausted cytotoxic T cells in gene expression networks of multisystem inflammatory syndrome in children

The Mount Sinai COVID-19 Biobank Team, 1 Dec 2021, In: Nature Communications. 12, 1, 4854.

Research output: Contribution to journal › Article › peer-review

Open Access

34 Scopus citations

Erratum: A randomized trial of combined PD-L1 and CTLA-4 inhibition with targeted low-dose or hypofractionated radiation for patients with metastatic colorectal cancer (Clinical Cancer Research (2021) 27 (2470-2480) DOI: 10.1158/1078-0432.CCR-20-4632)

Monjazeb, A. M., Giobbie-Hurder, A., Lako, A., Thrash, E. M., Brennick, R. C., Kao, K. Z., Manuszak, C., Gentzler, R. D., Tesfaye, A., Jabbour, S. K., Alese, O. B., Rahma, O. E., Cleary, J. M., Sharon, E., Mamon, H. J., Cho, M., Streicher, H., Chen, H. X., Ahmed, M. M., Mariño-Enríquez, A., & 14 othersKim-Schulze, S., Gnjatic, S., Maverakis, E., Marusina, A. I., Merleev, A. A., Severgnini, M., Pfaff, K. L., Lindsay, J., Weirather, J. L., Ranasinghe, S., Spektor, A., Rodig, S. J., Hodi, F. S. & Schoenfeld, J. D., 1 Sep 2021, In: Clinical Cancer Research. 27, 17, p. 4940 1 p.

Research output: Contribution to journal › Comment/debate

Open Access

2 Scopus citations

Immune profiling mass cytometry assay harmonization: Multicenter experience from CIMAC-CIDC

Sahaf, B., Pichavant, M., Lee, B. H., Duault, C., Thrash, E. M., Davila, M., Fernandez, N., Millerchip, K., Bentebibel, S. E., Haymaker, C., Sigal, N., Del Valle, D. M., Ranasinghe, S., Fayle, S., Sanchez-Espiridion, B., Zhang, J., Bernatchez, C., Wu, C. J., Wistuba, I. I., Kim-Schulze, S., & 7 othersGnjatic, S., Bendall, S. C., Song, M., Thurin, M., Jack Lee, J., Maecker, H. T. & Rahman, A., 15 Sep 2021, In: Clinical Cancer Research. 27, 18, p. 5062-5072 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Intestinal Host Response to SARS-CoV-2 Infection and COVID-19 Outcomes in Patients With Gastrointestinal Symptoms

Livanos, A. E., Jha, D., Cossarini, F., Gonzalez-Reiche, A. S., Tokuyama, M., Aydillo, T., Parigi, T. L., Ladinsky, M. S., Ramos, I., Dunleavy, K., Lee, B., Dixon, R. E., Chen, S. T., Martinez-Delgado, G., Nagula, S., Bruce, E. A., Ko, H. M., Glicksberg, B. S., Nadkarni, G., Pujadas, E., & 33 othersReidy, J., Naymagon, S., Grinspan, A., Ahmad, J., Tankelevich, M., Bram, Y., Gordon, R., Sharma, K., Houldsworth, J., Britton, G. J., Chen-Liaw, A., Spindler, M. P., Plitt, T., Wang, P., Cerutti, A., Faith, J. J., Colombel, J. F., Kenigsberg, E., Argmann, C., Merad, M., Gnjatic, S., Harpaz, N., Danese, S., Cordon-Cardo, C., Rahman, A., Schwartz, R. E., Kumta, N. A., Aghemo, A., Bjorkman, P. J., Petralia, F., van Bakel, H., Garcia-Sastre, A. & Mehandru, S., Jun 2021, In: Gastroenterology. 160, 7, p. 2435-2450.e34

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93 Scopus citations

Molecular and cellular features of CTLA-4 blockade for relapsed myeloid malignancies after transplantation

Penter, L., Zhang, Y., Savell, A., Huang, T., Cieri, N., Thrash, E. M., Kim-Schulze, S., Jhaveri, A., Fu, J., Ranasinghe, S., Li, S., Zhang, W., Hathaway, E. S., Nazzaro, M., Kim, H. T., Chen, H., Thurin, M., Rodig, S. J., Severgnini, M., Cibulskis, C., & 18 othersGabriel, S., Livak, K. J., Cutler, C., Antin, J. H., Nikiforow, S., Koreth, J., Ho, V. T., Armand, P., Ritz, J., Streicher, H., Neuberg, D., Hodi, F. S., Gnjatic, S., Soiffer, R. J., Liu, X. S., Davids, M. S., Bachireddy, P. & Wu, C. J., 10 Jun 2021, In: Blood. 137, 23, p. 3212-3217 6 p.

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20 Scopus citations

Multiplex tissue imaging harmonization: A multicenter experience from CIMAC-CIDC immuno-oncology biomarkers network

Akturk, G., Parra, E. R., Gjini, E., Lako, A., Jack Lee, J., Neuberg, D., Zhang, J., Yao, S., Laface, I., Rogic, A., Chen, P. H., Sanchez-Espiridion, B., Del Valle, D. M., Moravec, R., Kinders, R., Hudgens, C., Wu, C., Wistuba, I. I., Thurin, M., Hewitt, S. M., & 3 othersRodig, S., Gnjatic, S. & Tetzlaff, M. T., 15 Sep 2021, In: Clinical Cancer Research. 27, 18, p. 5072-5073 2 p.

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7 Scopus citations

Myeloid cell–associated resistance to PD-1/PD-L1 blockade in urothelial cancer revealed through bulk and single-cell RNA sequencing

Wang, L., Sfakianos, J. P., Beaumont, K. G., Akturk, G., Horowitz, A., Sebra, R. P., Farkas, A. M., Gnjatic, S., Hake, A., Izadmehr, S., Wiklund, P., Oh, W. K., Szabo, P. M., Wind-Rotolo, M., Unsal-Kacmaz, K., Yao, X., Schadt, E., Sharma, P., Bhardwaj, N., Zhu, J., & 1 othersGalsky, M. D., 1 Aug 2021, In: Clinical Cancer Research. 27, 15, p. 4287-4300 14 p.

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31 Scopus citations

Network for Biomarker Immunoprofiling for Cancer Immunotherapy: Cancer Immune Monitoring and Analysis Centers and Cancer Immunologic Data Commons (CIMAC-CIDC)

Chen, H. X., Song, M., Maecker, H. T., Gnjatic, S., Patton, D., Lee, J. J., Adam, S. J., Moravec, R., Liu, X. S., Cerami, E., Lindsay, J., Tang, M., Hodi, F. S., Wu, C. J., Wistuba, I. I., Al-Atrash, G., Bernatchez, C., Bendall, S. C., Hewitt, S. M., Sharon, E., & 20 othersStreicher, H., Enos, R. A., Bowman, M. D., Tatard-Leitman, V. M., Sanchez-Espiridion, B., Ranasinghe, S., Pichavant, M., Valle, D. M. D., Yu, J., Janssens, S., Peterson-Klaus, J., Rowe, C., Bongers, G., Jenq, R. R., Chang, C. C., Abrams, J. S., Mooney, M., Doroshow, J. H., Harris, L. N. & Thurin, M., 15 Sep 2021, In: Clinical Cancer Research. 27, 18, p. 5038-5048 11 p.

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5 Scopus citations

Pathophysiology of SARS-CoV-2: the Mount Sinai COVID-19 autopsy experience

Bryce, C., Grimes, Z., Pujadas, E., Ahuja, S., Beasley, M. B., Albrecht, R., Hernandez, T., Stock, A., Zhao, Z., AlRasheed, M. R., Chen, J., Li, L., Wang, D., Corben, A., Haines, G. K., Westra, W. H., Umphlett, M., Gordon, R. E., Reidy, J., Petersen, B., & 34 othersSalem, F., Fiel, M. I., El Jamal, S. M., Tsankova, N. M., Houldsworth, J., Mussa, Z., Veremis, B., Sordillo, E., Gitman, M. R., Nowak, M., Brody, R., Harpaz, N., Merad, M., Gnjatic, S., Liu, W. C., Schotsaert, M., Miorin, L., Aydillo Gomez, T. A., Ramos-Lopez, I., Garcia-Sastre, A., Donnelly, R., Seigler, P., Keys, C., Cameron, J., Moultrie, I., Washington, K. L., Treatman, J., Sebra, R., Jhang, J., Firpo, A., Lednicky, J., Paniz-Mondolfi, A., Cordon-Cardo, C. & Fowkes, M. E., Aug 2021, In: Modern Pathology. 34, 8, p. 1456-1467 12 p.

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144 Scopus citations

PD-L1 as a biomarker of response to immune-checkpoint inhibitors

Doroshow, D. B., Bhalla, S., Beasley, M. B., Sholl, L. M., Kerr, K. M., Gnjatic, S., Wistuba, I. I., Rimm, D. L., Tsao, M. S. & Hirsch, F. R., Jun 2021, In: Nature Reviews Clinical Oncology. 18, 6, p. 345-362 18 p.

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511 Scopus citations

Phase I/II trial of a long peptide vaccine (LPV7) plus toll-like receptor (TLR) agonists with or without incomplete Freund's adjuvant (IFA) for resected high-risk melanoma

Patel, S. P., Petroni, G. R., Roszik, J., Olson, W. C., Wages, N. A., Chianese-Bullock, K. A., Smolkin, M., Varhegyi, N., Gaughan, E., Smith, K. T., Haden, K., Hall, E. H., Gnjatic, S., Hwu, P. & Slingluff, C. L., 19 Aug 2021, In: Journal for ImmunoTherapy of Cancer. 9, 8, 003220.

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16 Scopus citations

Randomized phase II trial of a first-in-human cancer cell lysate vaccine in patients with thoracic malignancies

Zhang, M., Hong, J. A., Kunst, T. F., Bond, C. D., Kenney, C. M., Warga, C. L., Yeray, J., Lee, M. J., Yuno, A., Lee, S., Miettinen, M., Ripley, R. T., Hoang, C. D., Gnjatic, S., Trepel, J. B. & Schrump, D. S., Jul 2021, In: Translational Lung Cancer Research. 10, 7, p. 3079-3092 14 p.

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