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ASSOCIATE PROFESSOR | Neuroscience ASSOCIATE PROFESSOR | Neurosurgery
Biography
Dr. Roland Friedel, is an expert in the fields of developmental neurobiology and brain tumor research. His research team focuses on the question of how axon guidance molecules and growth factors regulate the migration and differentiation of brain tumor cells. He is also investigating the molecular characteristics that define brain tumor stem cells. Multi-Disciplinary Training Areas Cancer Biology [CAB], Developmental and Stem Cell Biology [DSCB], Neuroscience [NEU] Education Ph D, University of Munich Postdoctoral, Stanford University
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Dissect regulation of glial nets surrounding amyloid plaques in Alzheimer's disease
Friedel, R., Wang, M. & Zou, H.
5/05/22 → 30/04/25
Project: Research
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Tracing Hypoxic State and Hypoxia Memory in Glioblastoma Progression
National Institute of Neurological Disorders and Stroke
15/12/21 → 30/11/23
Project: Research
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Dissect governing factors for tumor stem cell dormancy in biomimetic vascular/GBM model
Zou, H., Dai, G., Friedel, R., Dai, G. G., Friedel, R. R. H. & Zou, H.
National Institute of Neurological Disorders and Stroke
1/08/18 → 31/07/23
Project: Research
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Plexin-B2 Function in Glioma Invasion
Friedel, R. & Friedel, R. H.
National Institute of Neurological Disorders and Stroke
1/04/16 → 30/06/23
Project: Research
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Tracking the in vivo proliferative history of human glioma-derived stem cells
National Institute of Neurological Disorders and Stroke
30/09/13 → 31/08/15
Project: Research
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Macrophages facilitate peripheral nerve regeneration by organizing regeneration tracks through Plexin-B2
Li, Y., Kang, S., Halawani, D., Wang, Y., Alves, C. J., Ramakrishnan, A., Estill, M., Shen, L., Li, F., He, X., Friedel, R. H. & Zou, H., 1 Feb 2022, In: Genes and Development. 36, 3-4, p. 133-148 16 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
A resource of targeted mutant mouse lines for 5,061 genes
International Mouse Phenotyping Consortium (IMPC), Apr 2021, In: Nature Genetics. 53, 4, p. 416-419 4 p.Research output: Contribution to journal › Comment/debate
32 Scopus citations -
BMP5/7 protect dopaminergic neurons in an α-synuclein mouse model of Parkinson's disease
Vitic, Z., Safory, H., Jovanovic, V. M., Sarusi, Y., Stavsky, A., Kahn, J., Kuzmina, A., Toker, L., Gitler, D., Taube, R., Friedel, R. H., Engelender, S. & Brodski, C., 1 Feb 2021, In: Brain. 144, 2, e15.Research output: Contribution to journal › Letter › peer-review
Open Access7 Scopus citations -
Diversified transcriptional responses of myeloid and glial cells in spinal cord injury shaped by HDAC3 activity
Wahane, S., Zhou, X., Zhou, X., Guo, L., Friedl, M. S., Kluge, M., Ramakrishnan, A., Shen, L., Friedel, C. C., Zhang, B., Friedel, R. H. & Zou, H., 24 Feb 2021, In: Science advances. 7, 9, eabd8811.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
Evolution and Diversity of Semaphorins and Plexins in Choanoflagellates
Alves, C. J., Ladeira, J. S., Hannah, T., Pedroso Dias, R. J., Zabala Capriles, P. V., Yotoko, K., Zou, H. & Friedel, R. H., 1 Mar 2021, In: Genome Biology and Evolution. 13, 3, evab035.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations
Press / Media
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Mount Sinai Receives More Than $10 Million in Grant Funding for Brain Tumor Research
Roland Friedel, Constantinos Hadjipanayis,, Nadejda Tsankova, Joshua Bederson & Hongyan Zou,
2/01/20 → 3/01/20
6 items of Media coverage
Press/Media
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