Research output per year
Research output per year
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ASSOCIATE PROFESSOR | Neuroscience ASSOCIATE PROFESSOR | Neurosurgery
Biography
Dr. Roland Friedel, is an expert in the fields of developmental neurobiology and brain tumor research. His research team focuses on the question of how axon guidance molecules and growth factors regulate the migration and differentiation of brain tumor cells. He is also investigating the molecular characteristics that define brain tumor stem cells. Multi-Disciplinary Training Areas Cancer Biology [CAB], Developmental and Stem Cell Biology [DSCB], Neuroscience [NEU] Education Ph D, University of Munich Postdoctoral, Stanford University
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Collaborations and top research areas from the last five years
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Invasion of glioma cells through confined space requires membrane tension regulation and mechano-electrical coupling via Plexin-B2
Junqueira Alves, C., Hannah, T., Sadia, S., Kolsteeg, C., Dixon, A., Wiener, R. J., Nguyen, H., Tipping, M. J., Silva Ladeira, J., Fernandes da Costa Franklin, P., de Paula Dutra de Nigro, N., Alves Dias, R., Zabala Capriles, P. V., Rodrigues Furtado de Mendonça, J. P., Slesinger, P. A., Costa, K. D., Zou, H. & Friedel, R. H., Dec 2025, In: Nature Communications. 16, 1, 272.Research output: Contribution to journal › Article › peer-review
Open Access -
Hypoxia drives shared and distinct transcriptomic changes in two invasive glioma stem cell lines
Marallano, V. J., Ughetta, M. E., Tejero, R., Nanda, S., Ramalingam, R., Stalbow, L., Sattiraju, A., Huang, Y., Ramakrishnan, A., Shen, L., Wojcinski, A., Kesari, S., Zou, H., Tsankov, A. M. & Friedel, R. H., Dec 2024, In: Scientific Reports. 14, 1, 7246.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Regulation of cell distancing in peri-plaque glial nets by Plexin-B1 affects glial activation and amyloid compaction in Alzheimer’s disease
Huang, Y., Wang, M., Ni, H., Zhang, J., Li, A., Hu, B., Junqueira Alves, C., Wahane, S., Rios de Anda, M., Ho, L., Li, Y., Kang, S., Neff, R., Kostic, A., Buxbaum, J. D., Crary, J. F., Brennand, K. J., Zhang, B., Zou, H. & Friedel, R. H., Aug 2024, In: Nature Neuroscience. 27, 8, p. 1489-1504 16 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Circadian clock regulator Bmal1 gates axon regeneration via Tet3 epigenetics in mouse sensory neurons
Halawani, D., Wang, Y., Ramakrishnan, A., Estill, M., He, X., Shen, L., Friedel, R. H. & Zou, H., Dec 2023, In: Nature Communications. 14, 1, 5165.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Corrigendum to Semaphorin 4C and 4G are ligands of Plexin-B2 required in cerebellar development [Mol. Cell. Neurosci., 2011 Feb;46(2):419–31](S1044743110002563)(10.1016/j.mcn.2010.11.005)
Maier, V., Jolicoeur, C., Rayburn, H., Takegahara, N., Kumanogoh, A., Kikutani, H., Tessier-Lavigne, M., Wurst, W. & Friedel, R. H., Jun 2023, In: Molecular and Cellular Neuroscience. 125, 103837.Research output: Contribution to journal › Comment/debate
Open Access
Press/Media
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Icahn School of Medicine at Mount Sinai Researchers Update Current Data on Gliomas (Invasion of glioma cells through confined space requires membrane tension regulation and mechano-electrical coupling via Plexin-B2)
Wiener, R., Costa, K., Friedel, R., Slesinger, P. & Zou, H.
17/01/25
1 item of Media coverage
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Investigators from Icahn School of Medicine at Mount Sinai Zero in on Alzheimer Disease (Regulation of Cell Distancing In Peri-plaque Glial Nets By Plexin-b1 Affects Glial Activation and Amyloid Compaction In Alzheimer's Disease)
Neff, R., Kang, S., Brennand, K., Wang, M., Li, A., Friedel, R., Ho, L., Zou, H. & Buxbaum, J.
14/06/24
1 item of Media coverage
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Early-stage research suggests new way to fight Alzheimer’s disease…
3/06/24
3 items of Media coverage
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Is it possible for a new approach to stop or delay progression?
3/06/24
1 item of Media coverage
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Alzheimer's treatments: what are the latest advances in science?
1/06/24
1 item of Media coverage
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