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(PQ9) Developing EZH2 Degraders for Treating Triple-Negative Breast Cancer
Jin, J. J., Jin, J., Parsons, R. E. & Parsons, R.
10/09/18 → 31/08/23
Project: Research
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A local tumor microenvironment acquired super-enhancer induces an oncogenic driver in colorectal carcinoma
Zhou, R. W., Xu, J., Martin, T. C., Zachem, A. L., He, J., Ozturk, S., Demircioglu, D., Bansal, A., Trotta, A. P., Giotti, B., Gryder, B., Shen, Y., Wu, X., Carcamo, S., Bosch, K., Hopkins, B., Tsankov, A., Steinhagen, R., Jones, D. R., Asara, J., & 7 others , Dec 2022, In: Nature Communications. 13, 1, 6041.Research output: Contribution to journal › Article › peer-review
Open Access -
Altered BAF occupancy and transcription factor dynamics in PBAF-deficient melanoma
Carcamo, S., Nguyen, C. B., Grossi, E., Filipescu, D., Alpsoy, A., Dhiman, A., Sun, D., Narang, S., Imig, J., Martin, T. C., Parsons, R., Aifantis, I., Tsirigos, A., Aguirre-Ghiso, J. A., Dykhuizen, E. C., Hasson, D. & Bernstein, E., 5 Apr 2022, In: Cell Reports. 39, 1, 110637.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Discovery of Potent, Selective, and in Vivo Efficacious AKT Kinase Protein Degraders via Structure-Activity Relationship Studies
Yu, X., Xu, J., Shen, Y., Cahuzac, K. M., Park, K. S., Dale, B., Liu, J., Parsons, R. E. & Jin, J., 24 Feb 2022, In: Journal of Medicinal Chemistry. 65, 4, p. 3644-3666 23 p.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
Inpatient Administration of Alpha-1-Adrenergic Receptor Blocking Agents Reduces Mortality in Male COVID-19 Patients
Li, S., Jun, T., Tyler, J., Schadt, E., Kao, Y. H., Wang, Z., Konig, M. F., Bettegowda, C., Vogelstein, J. T., Papadopoulos, N., Parsons, R. E., Chen, R., Schadt, E. E., Li, L. & Oh, W. K., 28 Feb 2022, In: Frontiers in Medicine. 9, 849222.Research output: Contribution to journal › Article › peer-review
Open Access -
Loss of PBRM1 Alters Promoter Histone Modifications and Activates ALDH1A1 to Drive Renal Cell Carcinoma
Schoenfeld, D. A., Zhou, R., Zairis, S., Su, W., Steinbach, N., Mathur, D., Bansal, A., Zachem, A. L., Tavarez, B., Hasson, D., Bernstein, E., Rabadan, R. & Parsons, R., Aug 2022, In: Molecular Cancer Research. 20, 8, p. 1193-1207 15 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations
Press / Media
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U.S. Patents Awarded to Inventors in New York (Dec. 2)
ANQI MA , Michael Ohlmeyer, Dongming Cai, Ramon Parsons & Jian Jin
2/12/22
1 item of Media coverage
Press/Media
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Compositions and Methods for Treating EZH2-mediated Cancer
ANQI MA , Ramon Parsons & Jian Jin
30/11/22
1 item of Media coverage
Press/Media
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US Patent Issued to Icahn School of Medicine at Mount Sinai on Nov. 29 for "Compositions and methods for treating EZH2-mediated cancer" (New York Inventors)
ANQI MA , Ramon Parsons & Jian Jin
30/11/22
1 item of Media coverage
Press/Media
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New Findings on Colon Cancer Described by Investigators at Icahn School of Medicine at Mount Sinai (A Local Tumor Microenvironment Acquired Super-enhancer Induces an Oncogenic Driver In Colorectal Carcinoma)
SAIT OZTURK , XUEWEI WU , Kaitlyn Bosch, Saul Carcamo, Bruno Giotti, Tiphaine Martin, Alexander Tsankov, Randolph Steinhagen, Emily Bernstein, Benjamin Hopkins, Ramon Parsons & Steven Itzkowitz
22/11/22
1 item of Media coverage
Press/Media