Personal profile
Headline
PROFESSOR & CHAIR | Neuroscience, DIRECTOR | Drug Discovery Institute
Biography
Biography Paul J. Kenny, PhD, is Ward-Coleman Professor and Chair of the https://icahn.mssm.edu/about/departments/neuroscience Nash Family Department of Neuroscience. Dr. Kenny also serves as the Director of the https://icahn.mssm.edu/research/ddi Drug Discovery Institute. His multidisciplinary research involves the study of behavioral paradigms, physiological analyses, and the molecular underpinnings of neurobehavioral disorders. Dr. Kenny is actively investigating the brains of rodents to uncover new signaling cascades that may play a role in addiction-like behaviors. The http://labs.icahn.mssm.edu/kennylab/ Kenny Laboratory is focused on understanding the neurobiological mechanisms of drug addiction, obesity and schizophrenia, with an emphasis on the role of nicotinic acetylcholine receptors (nAChRs) in these processes. They employ a multidisciplinary approach that includes complex behavioral paradigms, physiological analyses and molecular biological techniques. Current projects include the utilization of vector-based delivery systems to modify gene expression in the brains of rodents to identify novel signaling cascades that may play a role in addiction-like behaviors Awards 2020 - Annual Alton Ochsner Award Relating Smoking and Disease 2018- Daniel H. Efron Research Award 2015 - Tom Connor Distinguished Investigator Award 2012 - Mathilde Solowey Lecture Award in the Neurosciences Foundation for Advanced Education in the Sciences 2010 - Jacob P. Waletzky Memorial Award Society for Neuroscience Research The http://labs.icahn.mssm.edu/kennylab/ Kenny Laboratory is focused on understanding the neurobiological mechanisms of drug addiction, obesity and schizophrenia, with an emphasis on the role of nicotinic acetylcholine receptors (nAChRs) in these processes. They employ a multidisciplinary approach that includes complex behavioral paradigms, physiological analyses and molecular biological techniques. Current projects include the utilization of vector-based delivery systems to modify gene expression in the brains of rodents to identify novel signaling cascades that may play a role in addiction-like behaviors. https://pubmed.ncbi.nlm.nih.gov/?sort=pubdate&term=Kenny+PJ&cauthor_id=12829420 Search PubMed for articles
Fingerprint
Dive into the research topics where Paul Kenny is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
-
Gut-brain cholinergic signaling mediates the antiseizure effects of Bacteroides fragilis
Jia, Y., Chen, H., Zou, Q., Chen, S., Li, J., Chen, Y., Lu, L., Hong, F., Jia, S., Jing, X., Ren, J., Muhammad, F., Mi, J. Y., Duan, J., Liao, J., Liu, Q., Xu, F., Kenny, P. J., Han, M. H. & Wang, L. & 3 others, , 18 Mar 2026, In: Neuron. 114, 6, p. 1021-1044.e9Research output: Contribution to journal › Article › peer-review
-
Leveraging single-cell spatial transcriptomics and connectomics to resolve brain circuit function in psychiatry
Claypool, S. M. & Kenny, P. J., Jan 2026, In: Neuropsychopharmacology. 51, 1, p. 364-365 2 p.Research output: Contribution to journal › Comment/debate
-
Amygdala–liver signalling orchestrates glycaemic responses to stress
Carty, J. R. E., Devarakonda, K., O’Connor, R. M., Krek, A., Espinoza, D., Jimenez-Gonzalez, M., Alvarsson, A., Hampton, R. F., Li, R., Qiu, Y., Petri, S., Shtekler, A., Rajbhandari, A., Conner, K., Bayne, M., Garibay, D., Martin, J., Lehmann, V., Wang, L. & Beaumont, K. & 4 others, , 16 Oct 2025, In: Nature. 646, 8085, p. 697-706 10 p.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
Chronic stress drives depression by disrupting cellular housekeeping
Corona, A. & Kenny, P. J., 8 May 2025, In: Nature. 641, 8062, p. 317-318 2 p.Research output: Contribution to journal › Comment/debate
Open Access1 Scopus citations -
Craving, Impulsivity, and Subsequent Methamphetamine Use With Naltrexone-Bupropion Versus Placebo: Findings From a Randomized Clinical Trial
Jha, M. K., Ghitza, U. E., Carmody, T., Kuruvila, S., Shoptaw, S., Minhajuddin, A., Wakhlu, S., Schmitz, J. M., Coffin, P. O., Bart, G., Nunes, E. V., Kenny, P. & Trivedi, M. H., 2025, (Accepted/In press) In: Journal of Addiction Medicine. 1538.Research output: Contribution to journal › Article › peer-review
Open Access
Press/Media
-
Is a new weight-loss drug making people fall out of love?
6/04/26
4 items of Media coverage
Press/Media
-
The Inner Circle Acknowledges Jessica L. Ables As A Pinnacle Professional Member
Nestler, E. J., Kenny, P., Ables, J., Murrough, J. & Charney, D.
4/02/26
26 items of Media coverage
Press/Media
-
Icahn School of Medicine at Mount Sinai Awarded $6 Million NIH Grant to Advance Understanding of Down Syndrome
Goosens, K., Kenny, P. & Zaidi, M.
15/12/25 → 16/12/25
3 items of Media coverage
Press/Media
-
Icahn School of Medicine at Mount Sinai Awarded $6 Million NIH Grant to Advance Understanding of Down Syndrome
Goosens, K., Kenny, P. & Zaidi, M.
15/12/25
1 item of Media coverage
Press/Media
-
Mount Sinai Receives $8 Million from DataPhilanthropy to Accelerate Drug Discovery for CADASIL and Related Brain Disorders
17/09/25 → 18/09/25
4 items of Media coverage
Press/Media