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PROFESSOR | Neuroscience, PROFESSOR | Geriatrics and Palliative Medicine, PROFESSOR | Ophthalmology
Biography
Dr. Hof is the Regenstreif Professor of Neuroscience and Vice-Chair for the Department of Neuroscience. In the Department, Dr. Hof also leads the Kastor Neurobiology of Aging Laboratories. His laboratory has extensive expertise in the pathology of neuropsychiatric disorders and has established an international reputation in quantitative approaches to neuroanatomy and studies of brain evolution. Dr. Hof is the Editor-in-Chief of the Journal of Comparative Neurology. Websites * http://www.mssm.edu/departments-and-institutes/neuroscience Department of Neuroscience * http://www.mssm.edu/cnic/ Computational Neurobiology and Imaging Center * http://neuroscience.mssm.edu/hof Laboratory of Neuromorphology * http://www.autismbrainnet.com/ AutismBrainNet Multi-Disciplinary Training Areas Biophysics and Systems Pharmacology [BSP], Neuroscience [NEU] Education MD, University of Geneva School of Medicine The Scripps Research Institute
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Collaborations and top research areas from the last five years
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Human-specific features of the cerebellum and ZP2-regulated synapse development
Kim, S. K., Cherskov, A., Sindhwani, A., Choi, S. H., Kim, H., Li, M. L., Zhang, M., Mato-Blanco, X., Liu, Y., Micali, N., Young, D. M., Estacion, M., Zhang, Y., Ruiz-Jiménez, J. M., Nadkarni, A., Luria, V., Sindhu, S. K., Chatterjee, I., Shibata, A. & Liang, D. & 27 others, , 19 Mar 2026, In: Cell. 189, 6, p. 1802-1819.e28Research output: Contribution to journal › Article › peer-review
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Modifications of basal ganglia neuromodulatory systems
Raghanti, M. A., Smith, H. N., Armelli, K., Jones, D. N., Maycon, H., Edler, M. K., Hof, P. R. & Sherwood, C. C., 1 Jan 2026, Evolution of Nervous Systems. Elsevier, p. Vol4:275-Vol4:287Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
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Neurological aging and neurodegenerative disease in humans and great apes
Edler, M. K., Hearn, C. J., Guevara, E. E., Mhatre-Winters, I., Varghese, M., Freire-Cobo, C., Sherwood, C. C., Richardson, J. R., Raghanti, M. A. & Hof, P. R., 1 Jan 2026, Evolution of Nervous Systems. Elsevier, p. Vol4:310-Vol4:346Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
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Neurothermodynamics as a contributing factor shaping the mammalian brain
Manger, P. R., Benoit, J., Bhagwandin, A., Spocter, M. A., Weisbecker, V., Farke, A. A., Rule, J. P., McDonald, A., Adams, J. W., Lang, M. M., Bertrand, O. C., Racicot, R., Hof, P. R., do Amaral, R. V., Bruner, E., Neubauer, S. & Smaers, J., 1 Jan 2026, Evolution of Nervous Systems. Elsevier, p. Vol2:1-Vol2:40Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
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The cetacean brain
Orekhova, K., Gerussi, T., Sacchini, S., Patzke, N., Maloney, B., Graïc, J. M. & Hof, P. R., 1 Jan 2026, Evolution of Nervous Systems. Elsevier, p. Vol2:111-Vol2:162Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
Press/Media
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Researchers at Icahn School of Medicine at Mount Sinai Report New Data on Military and Defense (Chronic traumatic encephalopathy neuropathologic change in the Late Effects of Traumatic Brain Injury project: Findings in a community autopsy cohort)
Hof, P., Seifert, A., Crary, J., Dams-O’Connor,, K., Delman, B. & Folkerth, R.
28/10/25
1 item of Media coverage
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Report Summarizes Tauopathies Study Findings from Icahn School of Medicine at Mount Sinai (Molecular Signatures of Regional Vulnerability To Tauopathy In Excitatory Cortical Neurons)
Pereira, A., Wang, M., Sharma, A., Hof, P. & Patel, V.
2/07/25
1 item of Media coverage
Press/Media