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PROFESSOR | Neuroscience, PROFESSOR | Geriatrics and Palliative Medicine, PROFESSOR | Ophthalmology
Biography
Dr. Hof is the Regenstreif Professor of Neuroscience and Vice-Chair for the Department of Neuroscience. In the Department, Dr. Hof also leads the Kastor Neurobiology of Aging Laboratories. His laboratory has extensive expertise in the pathology of neuropsychiatric disorders and has established an international reputation in quantitative approaches to neuroanatomy and studies of brain evolution. Dr. Hof is the Editor-in-Chief of the Journal of Comparative Neurology. Websites * http://www.mssm.edu/departments-and-institutes/neuroscience Department of Neuroscience * http://www.mssm.edu/cnic/ Computational Neurobiology and Imaging Center * http://neuroscience.mssm.edu/hof Laboratory of Neuromorphology * http://www.autismbrainnet.com/ AutismBrainNet Multi-Disciplinary Training Areas Biophysics and Systems Pharmacology [BSP], Neuroscience [NEU] Education MD, University of Geneva School of Medicine The Scripps Research Institute
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Collaborations and top research areas from the last five years
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Human-specific features of the cerebellum and ZP2-regulated synapse development
Kim, S. K., Cherskov, A., Sindhwani, A., Choi, S. H., Kim, H., Li, M. L., Zhang, M., Mato-Blanco, X., Liu, Y., Micali, N., Young, D. M., Estacion, M., Zhang, Y., Ruiz-Jiménez, J. M., Nadkarni, A., Luria, V., Sindhu, S. K., Chatterjee, I., Shibata, A. & Liang, D. & 27 others, , 19 Mar 2026, In: Cell. 189, 6, p. 1802-1819.e28Research output: Contribution to journal › Article › peer-review
Open Access -
Von Economo Neuron Loss in Frontotemporal Dementia: A Meta-Analysis of Neuropathological Studies
Talmasov, D., Santillo, A. F. & Hof, P. R., 2026, (Accepted/In press) In: Annals of Clinical and Translational Neurology.Research output: Contribution to journal › Article › peer-review
Open Access -
Age-related changes in synapse ultrastructure and neuroprotective effect of dietary curcumin in the lateral prefrontal cortex layer 3 of the rhesus monkey
Freire-Cobo, C., Medalla, M., Varghese, M., Janssen, W. G. M., Luebke, J. I. & Hof, P. R., 2025, (Accepted/In press) In: GeroScience.Research output: Contribution to journal › Article › peer-review
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Basic Science and Pathogenesis
Broekaart, D., Sharma, A., Ramakrishnan, A., Subramaniyan, S., Wang, M., Patel, V., Zhang, B., Grinberg, L. T., Blitzer, R., Schmidt, E., Shen, L., Hof, P. R. & Pereira, A. C., 1 Dec 2025, In: Alzheimer's and Dementia. 21, p. e103209Research output: Contribution to journal › Article › peer-review
Open Access -
Basic Science and Pathogenesis
Mendes, T. V., Hof, P. R., Meyer, D., Varghese, M. & Eberlin, L. S., 1 Dec 2025, In: Alzheimer's and Dementia. 21, p. e105665Research output: Contribution to journal › Article › peer-review
Open Access
Press/Media
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Researchers at Icahn School of Medicine at Mount Sinai Report New Data on Military and Defense (Chronic traumatic encephalopathy neuropathologic change in the Late Effects of Traumatic Brain Injury project: Findings in a community autopsy cohort)
Hof, P., Seifert, A., Crary, J., Dams-O’Connor,, K., Delman, B. & Folkerth, R.
28/10/25
1 item of Media coverage
Press/Media
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Report Summarizes Tauopathies Study Findings from Icahn School of Medicine at Mount Sinai (Molecular Signatures of Regional Vulnerability To Tauopathy In Excitatory Cortical Neurons)
Pereira, A., Wang, M., Sharma, A., Hof, P. & Patel, V.
2/07/25
1 item of Media coverage
Press/Media