Filter
Article

Search results

  • 2019

    Integrative transcriptome imputation reveals tissue-specific and shared biological mechanisms mediating susceptibility to complex traits

    Zhang, W., Voloudakis, G., Rajagopal, V. M., Readhead, B., Dudley, J. T., Schadt, E. E., Björkegren, J. L. M., Kim, Y., Fullard, J. F., Hoffman, G. E. & Roussos, P., 1 Dec 2019, In: Nature Communications. 10, 1, 3834.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    56 Scopus citations
  • Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways

    Lam, M., Hill, W. D., Trampush, J. W., Yu, J., Knowles, E., Davies, G., Stahl, E., Huckins, L., Liewald, D. C., Djurovic, S., Melle, I., Sundet, K., Christoforou, A., Reinvang, I., DeRosse, P., Lundervold, A. J., Steen, V. M., Espeseth, T., Räikkönen, K. & Widen, E. & 48 others, Palotie, A., Eriksson, J. G., Giegling, I., Konte, B., Hartmann, A. M., Roussos, P., Giakoumaki, S., Burdick, K. E., Payton, A., Ollier, W., Chiba-Falek, O., Attix, D. K., Need, A. C., Cirulli, E. T., Voineskos, A. N., Stefanis, N. C., Avramopoulos, D., Hatzimanolis, A., Arking, D. E., Smyrnis, N., Bilder, R. M., Freimer, N. A., Cannon, T. D., London, E., Poldrack, R. A., Sabb, F. W., Congdon, E., Conley, E. D., Scult, M. A., Dickinson, D., Straub, R. E., Donohoe, G., Morris, D., Corvin, A., Gill, M., Hariri, A. R., Weinberger, D. R., Pendleton, N., Bitsios, P., Rujescu, D., Lahti, J., Le Hellard, S., Keller, M. C., Andreassen, O. A., Deary, I. J., Glahn, D. C., Malhotra, A. K. & Lencz, T., 1 Aug 2019, In: American Journal of Human Genetics. 105, 2, p. 334-350 17 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    64 Scopus citations
  • Open Access
    2 Scopus citations
  • The expression of long noncoding RNA NEAT1 is reduced in schizophrenia and modulates oligodendrocytes transcription

    Katsel, P., Roussos, P., Fam, P., Khan, S., Tan, W., Hirose, T., Nakagawa, S., Pletnikov, M. V. & Haroutunian, V., 1 Dec 2019, In: npj Schizophrenia. 5, 1, 3.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    41 Scopus citations
  • 2018

    A Bayesian framework for multiple trait colocalization from summary association statistics

    Giambartolomei, C., Liu, J. Z., Zhang, W., Hauberg, M., Shi, H., Boocock, J., Pickrell, J., Jaffe, A. E., Pasaniuc, B. & Roussos, P., 1 Aug 2018, In: Bioinformatics. 34, 15, p. 2538-2545 8 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    165 Scopus citations
  • Open Access
    29 Scopus citations
  • Age at first birth in women is genetically associated with increased risk of schizophrenia

    Ni, G., Gratten, J., Wray, N. R., Lee, S. H., Ripke, S., Neale, B. M., Corvin, A., Walters, J. T. R., Farh, K. H., Holmans, P. A., Lee, P., Bulik-Sullivan, B., Collier, D. A., Huang, H., Pers, T. H., Agartz, I., Agerbo, E., Albus, M., Alexander, M. & Amin, F. & 281 others, Bacanu, S. A., Begemann, M., Belliveau, R. A., Bene, J., Bergen, S. E., Bevilacqua, E., Bigdeli, T. B., Black, D. W., Bruggeman, R., Buccola, N. G., Buckner, R. L., Byerley, W., Cahn, W., Cai, G., Campion, D., Cantor, R. M., Carr, V. J., Carrera, N., Catts, S. V., Chambert, K. D., Chan, R. C. K., Chen, R. Y. L., Chen, E. Y. H., Cheng, W., Cheung, E. F. C., Chong, S. A., Cloninger, C. R., Cohen, D., Cohen, N., Cormican, P., Craddock, N., Crowley, J. J., Curtis, D., Davidson, M., Davis, K. L., Degenhardt, F., Del Favero, J., Demontis, D., Dikeos, D., Dinan, T., Djurovic, S., Donohoe, G., Drapeau, E., Duan, J., Dudbridge, F., Durmishi, N., Eichhammer, P., Eriksson, J., Escott-Price, V., Essioux, L., Fanous, A. H., Farrell, M. S., Frank, J., Franke, L., Freedman, R., Freimer, N. B., Friedl, M., Friedman, J. I., Fromer, M., Genovese, G., Georgieva, L., Giegling, I., Giusti-Rodríguez, P., Godard, S., Goldstein, J. I., Golimbet, V., Gopal, S., Haan, L. D., Hammer, C., Hamshere, M. L., Hansen, M., Hansen, T., Haroutunian, V., Hartmann, A. M., Henskens, F. A., Herms, S., Hirschhorn, J. N., Hoffmann, P., Hofman, A., Hollegaard, M. V., Hougaard, D. M., Ikeda, M., Joa, I., Juliá, A., Kahn, R. S., Kalaydjieva, L., Karachanak-Yankova, S., Karjalainen, J., Kavanagh, D., Keller, M. C., Kennedy, J. L., Khrunin, A., Kim, Y., Klovins, J., Knowles, J. A., Konte, B., Kucinskas, V., Kucinskiene, Z. A., Kuzelova-Ptackova, H., Kähler, A. K., Laurent, C., Keong, J. L. C., Legge, S. E., Lerer, B., Li, M., Li, T., Liang, K. Y., Lieberman, J., Limborska, S., Loughland, C. M., Lubinski, J., Lönnqvist, J., Macek, M., Magnusson, P. K. E., Maher, B. S., Maier, W., Mallet, J., Marsal, S., Mattheisen, M., Mattingsdal, M., McCarley, R. W., McDonald, C., McIntosh, A. M., Meier, S., Meijer, C. J., Melegh, B., Melle, I., Mesholam-Gately, R. I., Metspalu, A., Michie, P. T., Milani, L., Milanova, V., Mokrab, Y., Morris, D. W., Mors, O., Murphy, K. C., Murray, R. M., Myin-Germeys, I., Müller-Myhsok, B., Nelis, M., Nenadic, I., Nertney, D. A., Nestadt, G., Nicodemus, K. K., Nikitina-Zake, L., Nisenbaum, L., Nordin, A., O'callaghan, E., O'dushlaine, C., O'neill, F. A., Oh, S. Y., Olincy, A., Olsen, L., Os, J. V., Pantelis, C., Papadimitriou, G. N., Papiol, S., Parkhomenko, E., Pato, M. T., Paunio, T., Pejovic-Milovancevic, M., Perkins, D. O., Pietiläinen, O., Pimm, J., Pocklington, A. J., Powell, J., Price, A., Pulver, A. E., Purcell, S. M., Quested, D., Rasmussen, H. B., Reichenberg, A., Reimers, M. A., Richards, A. L., Roffman, J. L., Roussos, P., Ruderfer, D. M., Salomaa, V., Sanders, A. R., Schall, U., Schubert, C. R., Schulze, T. G., Schwab, S. G., Scolnick, E. M., Scott, R. J., Seidman, L. J., Shi, J., Sigurdsson, E., Silagadze, T., Silverman, J. M., Sim, K., Slominsky, P., Smoller, J. W., So, H. C., Spencer, C. C. A., Stahl, E. A., Stefansson, H., Steinberg, S., Stogmann, E., Straub, R. E., Strengman, E., Strohmaier, J., Stroup, T. S., Subramaniam, M., Suvisaari, J., Svrakic, D. M., Szatkiewicz, J. P., Söderman, E., Thirumalai, S., Toncheva, D., Tosato, S., Veijola, J., Waddington, J., Walsh, D., Wang, D., Wang, Q., Webb, B. T., Weiser, M., Wildenauer, D. B., Williams, N. M., Williams, S., Witt, S. H., Wolen, A. R., Wong, E. H. M., Wormley, B. K., Xi, H. S., Zai, C. C., Zheng, X., Zimprich, F., Stefansson, K., Visscher, P. M., Adolfsson, R., Andreassen, O. A., Blackwood, D. H. R., Bramon, E., Buxbaum, J. D., Børglum, A. D., Cichon, S., Darvasi, A., Domenici, E., Ehrenreich, H., Esko, T., Gejman, P. V., Gill, M., Gurling, H., Hultman, C. M., Iwata, N., Jablensky, A. V., Jönsson, E. G., Kendler, K. S., Kirov, G., Knight, J., Lencz, T., Levinson, D. F., Li, Q. S., Liu, J., Malhotra, A. K., McCarroll, S. A., McQuillin, A., Moran, J. L., Mortensen, P. B., Mowry, B. J., Nöthen, M. M., Ophoff, R. A., Owen, M. J., Palotie, A., Pato, C. N., Petryshen, T. L., Posthuma, D., Rietschel, M., Riley, B. P., Rujescu, D., Sham, P. C., Sklar, P., Clair, D. S., Weinberger, D. R., Wendland, J. R., Werge, T., Daly, M. J., Sullivan, P. F. & O'donovan, M. C., 1 Dec 2018, In: Scientific Reports. 8, 1, 10168.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    14 Scopus citations
  • Analysis of shared heritability in common disorders of the brain

    The Brainstorm Consortium, 22 Jun 2018, In: Science. 360, 6395, 8757.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    1341 Scopus citations
  • An atlas of chromatin accessibility in the adult human brain

    Fullard, J. F., Hauberg, M. E., Bendl, J., Egervari, G., Cirnaru, M. D., Reach, S. M., Motl, J., Ehrlich, M. E., Hurd, Y. L. & Roussos, P., Aug 2018, In: Genome Research. 28, 8, p. 1243-1252 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    116 Scopus citations
  • Brain Cell Type Specific Gene Expression and Co-expression Network Architectures

    McKenzie, A. T., Wang, M., Hauberg, M. E., Fullard, J. F., Kozlenkov, A., Keenan, A., Hurd, Y. L., Dracheva, S., Casaccia, P., Roussos, P. & Zhang, B., 1 Dec 2018, In: Scientific Reports. 8, 1, 8868.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    262 Scopus citations
  • Cell-specific histone modification maps in the human frontal lobe link schizophrenia risk to the neuronal epigenome

    Girdhar, K., Hoffman, G. E., Jiang, Y., Brown, L., Kundakovic, M., Hauberg, M. E., Francoeur, N. J., Wang, Y. C., Shah, H., Kavanagh, D. H., Zharovsky, E., Jacobov, R., Wiseman, J. R., Park, R., Johnson, J. S., Kassim, B. S., Sloofman, L., Mattei, E., Weng, Z. & Sieberts, S. K. & 6 others, Peters, M. A., Harris, B. T., Lipska, B. K., Sklar, P., Roussos, P. & Akbarian, S., 1 Aug 2018, In: Nature Neuroscience. 21, 8, p. 1126-1136 11 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    83 Scopus citations
  • Comprehensive functional genomic resource and integrative model for the human brain

    Wang, D., Liu, S., Warrell, J., Won, H., Shi, X., Navarro, F. C. P., Clarke, D., Gu, M., Emani, P., Yang, Y. T., Min, X., Gandal, M. J., Lou, S., Zhang, J., Park, J. J., Yan, C., KyongRhie, S., Manakongtreecheep, K., Zhou, H. & Aparna Natha, A. & 20 others, Peters, M., Mattei, E., Fitzgerald, D., Brunetti, T., Moore, J., Jiang, Y., Girdhar, K., Hoffman, G. E., Kalayci, S., Gümüş, Z. H., Crawford, G. E., Roussos, P., Akbarian, S., Jaffe, A. E., White, K. P., Weng, Z., Sestan, N., Geschwind, D. H., Knowles, J. A. & Gerstein, M. B., 14 Dec 2018, In: Science. 362, 6420, 1266.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    533 Scopus citations
  • Dimensional traits of schizotypy associated with glycine receptor glra1 polymorphism: An exploratory candidate-gene association study

    Vora, A. K., Fisher, A. M., New, A. S., Hazlett, E. A., McNamara, M., Yuan, Q., Zhou, Z., Hodgkinson, C., Goldman, D., Siever, L. J., Roussos, P. & Perez-Rodriguez, M. M., 2018, In: Journal of Personality Disorders. 32, 3, p. 421-432 12 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    4 Scopus citations
  • Open Access
    106 Scopus citations
  • Evaluation of chromatin accessibility in prefrontal cortex of individuals with schizophrenia

    Bryois, J., Garrett, M. E., Song, L., Safi, A., Giusti-Rodriguez, P., Johnson, G. D., Shieh, A. W., Buil, A., Fullard, J. F., Roussos, P., Sklar, P., Akbarian, S., Haroutunian, V., Stockmeier, C. A., Wray, G. A., White, K. P., Liu, C., Reddy, T. E., Ashley-Koch, A. & Sullivan, P. F. & 1 others, Crawford, G. E., 1 Dec 2018, In: Nature Communications. 9, 1, 3121.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    106 Scopus citations
  • Frontal and temporal cortical volume, white matter tract integrity, and hemispheric asymmetry in schizotypal personality disorder

    Chan, C. C., Szeszko, P. R., Wong, E., Tang, C. Y., Kelliher, C., Penner, J. D., Perez-Rodriguez, M. M., Rosell, D. R., McClure, M., Roussos, P., New, A. S., Siever, L. J. & Hazlett, E. A., Jul 2018, In: Schizophrenia Research. 197, p. 226-232 7 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    9 Scopus citations
  • Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence

    Savage, J. E., Jansen, P. R., Stringer, S., Watanabe, K., Bryois, J., De Leeuw, C. A., Nagel, M., Awasthi, S., Barr, P. B., Coleman, J. R. I., Grasby, K. L., Hammerschlag, A. R., Kaminski, J. A., Karlsson, R., Krapohl, E., Lam, M., Nygaard, M., Reynolds, C. A., Trampush, J. W. & Young, H. & 97 others, Zabaneh, D., Hägg, S., Hansell, N. K., Karlsson, I. K., Linnarsson, S., Montgomery, G. W., Muñoz-Manchado, A. B., Quinlan, E. B., Schumann, G., Skene, N. G., Webb, B. T., White, T., Arking, D. E., Avramopoulos, D., Bilder, R. M., Bitsios, P., Burdick, K. E., Cannon, T. D., Chiba-Falek, O., Christoforou, A., Cirulli, E. T., Congdon, E., Corvin, A., Davies, G., Deary, I. J., Derosse, P., Dickinson, D., Djurovic, S., Donohoe, G., Conley, E. D., Eriksson, J. G., Espeseth, T., Freimer, N. A., Giakoumaki, S., Giegling, I., Gill, M., Glahn, D. C., Hariri, A. R., Hatzimanolis, A., Keller, M. C., Knowles, E., Koltai, D., Konte, B., Lahti, J., Le Hellard, S., Lencz, T., Liewald, D. C., London, E., Lundervold, A. J., Malhotra, A. K., Melle, I., Morris, D., Need, A. C., Ollier, W., Palotie, A., Payton, A., Pendleton, N., Poldrack, R. A., Räikkönen, K., Reinvang, I., Roussos, P., Rujescu, D., Sabb, F. W., Scult, M. A., Smeland, O. B., Smyrnis, N., Starr, J. M., Steen, V. M., Stefanis, N. C., Straub, R. E., Sundet, K., Tiemeier, H., Voineskos, A. N., Weinberger, D. R., Widen, E., Yu, J., Abecasis, G., Andreassen, O. A., Breen, G., Christiansen, L., Debrabant, B., Dick, D. M., Heinz, A., Hjerling-Leffler, J., Ikram, M. A., Kendler, K. S., Martin, N. G., Medland, S. E., Pedersen, N. L., Plomin, R., Polderman, T. J. C., Ripke, S., Van Der Sluis, S., Sullivan, P. F., Vrieze, S. I., Wright, M. J. & Posthuma, D., 1 Jul 2018, In: Nature Genetics. 50, 7, p. 912-919 8 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    718 Scopus citations
  • Open Access
    452 Scopus citations
  • Open Access
    100 Scopus citations
  • Open Access
    470 Scopus citations
  • Landscape of Conditional eQTL in Dorsolateral Prefrontal Cortex and Co-localization with Schizophrenia GWAS

    the CommonMind Consortium, 7 Jun 2018, In: American Journal of Human Genetics. 102, 6, p. 1169-1184 16 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    90 Scopus citations
  • Meta-analysis on the association between genetic polymorphisms and prepulse inhibition of the acoustic startle response

    Quednow, B. B., Ejebe, K., Wagner, M., Giakoumaki, S. G., Bitsios, P., Kumari, V. & Roussos, P., Aug 2018, In: Schizophrenia Research. 198, p. 52-59 8 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    28 Scopus citations
  • Multi-Trait analysis of gwas and biological insights into cognition: A response to hill (2018)

    Lam, M., Trampush, J. W., Yu, J., Knowles, E., Djurovic, S., Melle, I., Sundet, K., Christoforou, A., Reinvang, I., Derosse, P., Lundervold, A. J., Steen, V. M., Espeseth, T., Räikkönen, K., Widen, E., Palotie, A., Eriksson, J. G., Giegling, I., Konte, B. & Roussos, P. & 41 others, Giakoumaki, S., Burdick, K. E., Payton, A., Ollier, W., Chiba-Falek, O., Attix, D. K., Need, A. C., Cirulli, E. T., Voineskos, A. N., Stefanis, N. C., Avramopoulos, D., Hatzimanolis, A., Arking, D. E., Smyrnis, N., Bilder, R. M., Freimer, N. A., Cannon, T. D., London, E., Poldrack, R. A., Sabb, F. W., Congdon, E., Conley, E. D., Scult, M. A., Dickinson, D., Straub, R. E., Donohoe, G., Morris, D., Corvin, A., Gill, M., Hariri, A. R., Weinberger, D. R., Pendleton, N., Bitsios, P., Rujescu, D., Lahti, J., Hellard, S. L., Keller, M. C., Andreassen, O. A., Glahn, D. C., Malhotra, A. K. & Lencz, T., 1 Oct 2018, In: Twin Research and Human Genetics. 21, 5, p. 394-397 4 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    3 Scopus citations
  • Neuron-specific signatures in the chromosomal connectome associated with schizophrenia risk

    Rajarajan, P., Borrman, T., Liao, W., Schrode, N., Flaherty, E., Casiño, C., Powell, S., Yashaswini, C., LaMarca, E. A., Kassim, B., Javidfar, B., Espeso-Gil, S., Li, A., Won, H., Geschwind, D. H., Ho, S. M., MacDonald, M., Hoffman, G. E., Roussos, P. & Zhang, B. & 4 others, Hahn, C. G., Weng, Z., Brennand, K. J. & Akbarian, S., 14 Dec 2018, In: Science. 362, 6420, 1269.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    137 Scopus citations
  • Open Access
    19 Scopus citations
  • Stress-dependent association between polygenic risk for schizophrenia and schizotypal traits in young army recruits

    Hatzimanolis, A., Avramopoulos, D., Arking, D. E., Moes, A., Bhatnagar, P., Lencz, T., Malhotra, A. K., Giakoumaki, S. G., Roussos, P., Smyrnis, N., Bitsios, P. & Stefanis, N. C., Mar 2018, In: Schizophrenia Bulletin. 44, 2, p. 338-347 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    33 Scopus citations
  • Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function

    Davies, G., Lam, M., Harris, S. E., Trampush, J. W., Luciano, M., Hill, W. D., Hagenaars, S. P., Ritchie, S. J., Marioni, R. E., Fawns-Ritchie, C., Liewald, D. C. M., Okely, J. A., Ahola-Olli, A. V., Barnes, C. L. K., Bertram, L., Bis, J. C., Burdick, K. E., Christoforou, A., Derosse, P. & Djurovic, S. & 201 others, Espeseth, T., Giakoumaki, S., Giddaluru, S., Gustavson, D. E., Hayward, C., Hofer, E., Ikram, M. A., Karlsson, R., Knowles, E., Lahti, J., Leber, M., Li, S., Mather, K. A., Melle, I., Morris, D., Oldmeadow, C., Palviainen, T., Payton, A., Pazoki, R., Petrovic, K., Reynolds, C. A., Sargurupremraj, M., Scholz, M., Smith, J. A., Smith, A. V., Terzikhan, N., Thalamuthu, A., Trompet, S., Van Der Lee, S. J., Ware, E. B., Windham, B. G., Wright, M. J., Yang, J., Yu, J., Ames, D., Amin, N., Amouyel, P., Andreassen, O. A., Armstrong, N. J., Assareh, A. A., Attia, J. R., Attix, D., Avramopoulos, D., Bennett, D. A., Böhmer, A. C., Boyle, P. A., Brodaty, H., Campbell, H., Cannon, T. D., Cirulli, E. T., Congdon, E., Conley, E. D., Corley, J., Cox, S. R., Dale, A. M., Dehghan, A., Dick, D., Dickinson, D., Eriksson, J. G., Evangelou, E., Faul, J. D., Ford, I., Freimer, N. A., Gao, H., Giegling, I., Gillespie, N. A., Gordon, S. D., Gottesman, R. F., Griswold, M. E., Gudnason, V., Harris, T. B., Hartmann, A. M., Hatzimanolis, A., Heiss, G., Holliday, E. G., Joshi, P. K., Kähönen, M., Kardia, S. L. R., Karlsson, I., Kleineidam, L., Knopman, D. S., Kochan, N. A., Konte, B., Kwok, J. B., Le Hellard, S., Lee, T., Lehtimäki, T., Li, S. C., Liu, T., Koini, M., London, E., Longstreth, W. T., Lopez, O. L., Loukola, A., Luck, T., Lundervold, A. J., Lundquist, A., Lyytikäinen, L. P., Martin, N. G., Montgomery, G. W., Murray, A. D., Need, A. C., Noordam, R., Nyberg, L., Ollier, W., Papenberg, G., Pattie, A., Polasek, O., Poldrack, R. A., Psaty, B. M., Reppermund, S., Riedel-Heller, S. G., Rose, R. J., Rotter, J. I., Roussos, P., Rovio, S. P., Saba, Y., Sabb, F. W., Sachdev, P. S., Satizabal, C. L., Schmid, M., Scott, R. J., Scult, M. A., Simino, J., Slagboom, P. E., Smyrnis, N., Soumaré, A., Stefanis, N. C., Stott, D. J., Straub, R. E., Sundet, K., Taylor, A. M., Taylor, K. D., Tzoulaki, I., Tzourio, C., Uitterlinden, A., Vitart, V., Voineskos, A. N., Kaprio, J., Wagner, M., Wagner, H., Weinhold, L., Wen, K. H., Widen, E., Yang, Q., Zhao, W., Adams, H. H. H., Arking, D. E., Bilder, R. M., Bitsios, P., Boerwinkle, E., Chiba-Falek, O., Corvin, A., De Jager, P. L., Debette, S., Donohoe, G., Elliott, P., Fitzpatrick, A. L., Gill, M., Glahn, D. C., Hägg, S., Hansell, N. K., Hariri, A. R., Ikram, M. K., Jukema, J. W., Vuoksimaa, E., Keller, M. C., Kremen, W. S., Launer, L., Lindenberger, U., Palotie, A., Pedersen, N. L., Pendleton, N., Porteous, D. J., Räikkönen, K., Raitakari, O. T., Ramirez, A., Reinvang, I., Rudan, I., Rujescu, D., Schmidt, R., Schmidt, H., Schofield, P. W., Schofield, P. R., Starr, J. M., Steen, V. M., Trollor, J. N., Turner, S. T., Van Duijn, C. M., Villringer, A., Weinberger, D. R., Weir, D. R., Wilson, J. F., Malhotra, A., McIntosh, A. M., Gale, C. R., Seshadri, S., Mosley, T. H., Bressler, J., Lencz, T. & Deary, I. J., 1 Dec 2018, In: Nature Communications. 9, 1, 2098.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    423 Scopus citations
  • THC exposure of human iPSC neurons impacts genes associated with neuropsychiatric disorders

    Guennewig, B., Bitar, M., Obiorah, I., Hanks, J., O'Brien, E. A., Kaczorowski, D. C., Hurd, Y. L., Roussos, P., Brennand, K. J. & Barry, G., 1 Dec 2018, In: Translational Psychiatry. 8, 1, 89.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    30 Scopus citations
  • The Mount Sinai cohort of large-scale genomic, transcriptomic and proteomic data in Alzheimer’s disease

    Wang, M., Beckmann, N. D., Roussos, P., Wang, E., Zhou, X., Wang, Q., Ming, C., Neff, R., Ma, W., Fullard, J. F., Hauberg, M. E., Bendl, J., Peters, M. A., Logsdon, B., Wang, P., Mahajan, M., Mangravite, L. M., Dammer, E. B., Duong, D. M. & Lah, J. J. & 9 others, Seyfried, N. T., Levey, A. I., Buxbaum, J. D., Ehrlich, M., Gandy, S., Katsel, P., Haroutunian, V., Schadt, E. & Zhang, B., 11 Sep 2018, In: Scientific data. 5, 180185.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    237 Scopus citations
  • Winter birth, urbanicity and immigrant status predict psychometric schizotypy dimensions in adolescents

    Mimarakis, D., Roumeliotaki, T., Roussos, P., Giakoumaki, S. G. & Bitsios, P., Jan 2018, In: European Psychiatry. 47, p. 9-18 10 p.

    Research output: Contribution to journalArticlepeer-review

    10 Scopus citations
  • 2017

    A functional genomics predictive network model identifies regulators of inflammatory bowel disease

    Peters, L. A., Perrigoue, J., Mortha, A., Iuga, A., Song, W. M., Neiman, E. M., Llewellyn, S. R., Di Narzo, A., Kidd, B. A., Telesco, S. E., Zhao, Y., Stojmirovic, A., Sendecki, J., Shameer, K., Miotto, R., Losic, B., Shah, H., Lee, E., Wang, M. & Faith, J. J. & 18 others, Kasarskis, A., Brodmerkel, C., Curran, M., Das, A., Friedman, J. R., Fukui, Y., Humphrey, M. B., Iritani, B. M., Sibinga, N., Tarrant, T. K., Argmann, C., Hao, K., Roussos, P., Zhu, J., Zhang, B., Dobrin, R., Mayer, L. F. & Schadt, E. E., 1 Oct 2017, In: Nature Genetics. 49, 10, p. 1437-1449 13 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    179 Scopus citations
  • Analysis of Transcriptional Variability in a Large Human iPSC Library Reveals Genetic and Non-genetic Determinants of Heterogeneity

    Carcamo-Orive, I., Hoffman, G. E., Cundiff, P., Beckmann, N. D., D'Souza, S. L., Knowles, J. W., Patel, A., Papatsenko, D., Abbasi, F., Reaven, G. M., Whalen, S., Lee, P., Shahbazi, M., Henrion, M. Y. R., Zhu, K., Wang, S., Roussos, P., Schadt, E. E., Pandey, G. & Chang, R. & 2 others, Quertermous, T. & Lemischka, I., 6 Apr 2017, In: Cell Stem Cell. 20, 4, p. 518-532.e9

    Research output: Contribution to journalArticlepeer-review

    Open Access
    186 Scopus citations
  • Open Access
    707 Scopus citations
  • Evidence for genetic heterogeneity between clinical subtypes of bipolar disorder

    Charney, A. W., Ruderfer, D. M., Stahl, E. A., Moran, J. L., Chambert, K., Belliveau, R. A., Forty, L., Gordon-Smith, K., Di Florio, A., Lee, P. H., Bromet, E. J., Buckley, P. F., Escamilla, M. A., Fanous, A. H., Fochtmann, L. J., Lehrer, D. S., Malaspina, D., Marder, S. R., Morley, C. P. & Nicolini, H. & 25 others, Perkins, D. O., Rakofsky, J. J., Rapaport, M. H., Medeiros, H., Sobell, J. L., Green, E. K., Backlund, L., Bergen, S. E., Juréus, A., Schalling, M., Lichtenstein, P., Roussos, P., Knowles, J. A., Jones, I., Jones, L. A., Hultman, C. M., Perlis, R. H., Purcell, S. M., McCarroll, S. A., Pato, C. N., Pato, M. T., Craddock, N., Landén, M., Smoller, J. W. & Sklar, P., 2017, In: Translational Psychiatry. 7, 1, e993.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    140 Scopus citations
  • Genetic correlation between amyotrophic lateral sclerosis and schizophrenia

    McLaughlin, R. L., Schijven, D., Van Rheenen, W., Van Eijk, K. R., O'Brien, M., Kahn, R. S., Ophoff, R. A., Goris, A., Bradley, D. G., Al-Chalabi, A., Van Den Berg, L. H., Luykx, J. J., Hardiman, O., Veldink, J. H., Shatunov, A., Dekker, A. M., Diekstra, F. P., Pulit, S. L., Van Der Spek, R. A. A. & Van Doormaal, P. T. C. & 416 others, Sproviero, W., Jones, A. R., Nicholson, G. A., Rowe, D. B., Pamphlett, R., Kiernan, M. C., Bauer, D., Kahlke, T., Williams, K., Eftimov, F., Fogh, I., Ticozzi, N., Lin, K., Millecamps, S., Salachas, F., Meininger, V., Carvalho, M. D., Pinto, S., Mora, J. S., Rojas-Garcyá, R., Polak, M., Chandran, S., Colville, S., Swingler, R., Morrison, K. E., Shaw, P. J., Hardy, J., Orrell, R. W., Pittman, A., Sidle, K., Fratta, P., Malaspina, A., Petri, S., Abdulla, S., Drepper, C., Sendtner, M., Meyer, T., Wiedau-Pazos, M., Lomen-Hoerth, C., Deerlin, V. M. V., Trojanowski, J. Q., Elman, L., McCluskey, L., Basak, N., Meitinger, T., Lichtner, P., Blagojevic-Radivojkov, M., Andres, C. R., Maurel, C., Bensimon, G., Landwehrmeyer, B., Brice, A., Payan, C. A. M., Saker-Delye, S., Durr, A., Wood, N., Tittmann, L., Lieb, W., Franke, A., Rietschel, M., Cichon, S., Nothen, M. M., Amouyel, P., Tzourio, C., Dartigues, J. F., Uitterlinden, A. G., Rivadeneira, F., Estrada, K., Hofman, A., Curtis, C., Derkooi, A. J. V., De Visser, M., Weber, M., Shaw, C. E., Smith, B. N., Pansarasa, O., Cereda, C., Bo, R. D., Comi, G. P., D'Alfonso, S., Bertolin, C., Soraru, G., Mazzini, L., Pensato, V., Gellera, C., Tiloca, C., Ratti, A., Calvo, A., Moglia, C., Brunetti, M., Arcuti, S., Capozzo, R., Zecca, C., Lunetta, C., Penco, S., Riva, N., Padovani, A., Filosto, M., Blair, I., Nigel Leigh, P., Casale, F., Chio, A., Beghi, E., Pupillo, E., Tortelli, R., Logroscino, G., Powell, J., Ludolph, A. C., Weishaupt, J. H., Robberecht, W., Damme, P. V., Brown, R. H., Glass, J., Landers, J. E., Andersen, P. M., Corcia, P., Vourc'H, P., Silani, V., Es, M. A. V., Pasterkamp, R. J., Lewis, C. M., Breen, G., Ripke, S., Neale, B. M., Corvin, A., Walters, J. T. R., Farh, K. H., Holmans, P. A., Lee, P., Bulik-Sullivan, B., Collier, D. A., Huang, H., Pers, T. H., Agartz, I., Agerbo, E., Albus, M., Alexander, M., Amin, F., Bacanu, S. A., Begemann, M., Belliveau, R. A., Bene, J., Bergen, S. E., Bevilacqua, E., Bigdeli, T. B., Black, D. W., Bruggeman, R., Buccola, N. G., Buckner, R. L., Byerley, W., Cahn, W., Cai, G., Campion, D., Cantor, R. M., Carr, V. J., Carrera, N., Catts, S. V., Chambert, K. D., Chan, R. C. K., Chan, R. Y. L., Chen, E. Y. H., Cheng, W., Cheung, E. F. C., Chong, S. A., Cloninger, C. R., Cohen, D., Cohen, N., Cormican, P., Craddock, N., Crowley, J. J., Curtis, D., Davidson, M., Davis, K. L., Degenhardt, F., Favero, J. D., Demontis, D., Dikeos, D., Dinan, T., Djurovic, S., Donohoe, G., Drapeau, E., Duan, J., Dudbridge, F., Durmishi, N., Eichhammer, P., Eriksson, J., Escott-Price, V., Essioux, L., Fanous, A. H., Farrell, M. S., Frank, J., Franke, L., Freedman, R., Freimer, N. B., Friedl, M., Friedman, J. I., Fromer, M., Genovese, G., Georgieva, L., Giegling, I., Giusti-Rodrýguez, P., Godard, S., Goldstein, J. I., Golimbet, V., Gopal, S., Gratten, J., De Haan, L., Hammer, C., Hamshere, M. L., Hansen, M., Hansen, T., Haroutunian, V., Hartmann, A. M., Henskens, F. A., Herms, S., Hirschhorn, J. N., Hoffmann, P., Hofman, A., Hollegaard, M. V., Hougaard, D. M., Ikeda, M., Joa, I., Julia, A., Kalaydjieva, L., Karachanak-Yankova, S., Karjalainen, J., Kavanagh, D., Keller, M. C., Kennedy, J. L., Khrunin, A., Kim, Y., Klovins, J., Knowles, J. A., Konte, B., Kucinskas, V., Kucinskiene, Z. A., Kuzelova-Ptackova, H., Kahler, A. K., Laurent, C., Lee, J., Hong Lee, S., Legge, S. E., Lerer, B., Li, M., Li, T., Liang, K. Y., Lieberman, J., Limborska, S., Loughland, C. M., Lubinski, J., Lonnqvist, J., MacEk, M., Magnusson, P. K. E., Maher, B. S., Maier, W., Mallet, J., Marsal, S., Mattheisen, M., Mattingsdal, M., McCarley, R. W., McDonald, C., McIntosh, A. M., Meier, S., Meijer, C. J., Melegh, B., Melle, I., Mesholam-Gately, R. I., Metspalu, A., Michie, P. T., Milani, L., Milanova, V., Mokrab, Y., Morris, D. W., Mors, O., Murphy, K. C., Murray, R. M., Myin-Germeys, I., Muller-Myhsok, B., Nelis, M., Nenadic, I., Nertney, D. A., Nestadt, G., Nicodemus, K. K., Nikitina-Zake, L., Nisenbaum, L., Nordin, A., O'Callaghan, E., O'Dushlaine, C., Anthony O'Neill, F., Oh, S. Y., Olincy, A., Olsen, L., Vanos, J., Pantelis, C., Papadimitriou, G. N., Papiol, S., Parkhomenko, E., Pato, M. T., Paunio, T., Pejovic-Milovancevic, M., Perkins, D. O., Pietilainen, O., Pimm, J., Pocklington, A. J., Price, A., Pulver, A. E., Purcell, S. M., Quested, D., Rasmussen, H. B., Reichenberg, A., Reimers, M. A., Richards, A. L., Roffman, J. L., Roussos, P., Ruderfer, D. M., Salomaa, V., Sanders, A. R., Schall, U., Schubert, C. R., Schulze, T. G., Schwab, S. G., Scolnick, E. M., Scott, R. J., Seidman, L. J., Shi, J., Sigurdsson, E., Silagadze, T., Silverman, J. M., Sim, K., Slominsky, P., Smoller, J. W., So, H. C., Spencer, C. C. A., Stah, E. A., Stefansson, H., Steinberg, S., Stogmann, E., Straub, R. E., Strengman, E., Strohmaier, J., Scott Stroup, T., Subramaniam, M., Suvisaari, J., Svrakic, D. M., Szatkiewicz, J. P., Söderman, E., Thirumalai, S., Toncheva, D., Tosato, S., Veijola, J., Waddington, J., Walsh, D., Wang, D., Wang, Q., Webb, B. T., Weiser, M., Wildenauer, D. B., Williams, N. M., Williams, S., Witt, S. H., Wolen, A. R., Wong, E. H. M., Wormley, B. K., Xi, H. S., Zai, C. C., Zheng, X., Zimprich, F., Wray, N. R., Stefansson, K., Visscher, P. M., Adolfsson, R., Andreassen, O. A., Blackwood, D. H. R., Bramon, E., Buxbaum, J. D., Børglum, A. D., Darvasi, A., Domenici, E., Ehrenreich, H., Esko, T., Gejman, P. V., Gil, M., Gurling, H., Hultman, C. M., Iwata, N., Jablensky, A. V., Jonsson, E. G., Kendler, K. S., Kirov, G., Knight, J., Lencz, T., Levinson, D. F., Li, Q. S., Liu, J., Malhotra, A. K., McCarrol, S. A., McQuillin, A., Moran, J. L., Mortensen, P. B., Mowry, B. J., Owen, M. J., Palotie, A., Pato, C. N., Petryshen, T. L., Posthuma, D., Riley, B. P., Rujescu, D., Sham, P. C., Sklar, P., Clair, D. S., Weinberger, D. R., Wendland, J. R., Werge, T., Daly, M. J., Sullivan, P. F. & O'Donovan, M. C., 21 Mar 2017, In: Nature Communications. 8, 14774.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    93 Scopus citations
  • GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: A report from the COGENT consortium

    Trampush, J. W., Yang, M. L. Z., Yu, J., Knowles, E., Davies, G., Liewald, D. C., Starr, J. M., Djurovic, S., Melle, I., Sundet, K., Christoforou, A., Reinvang, I., Derosse, P., Lundervold, A. J., Steen, V. M., Espeseth, T., Räikkönen, K., Widen, E., Palotie, A. & Eriksson, J. G. & 46 others, Giegling, I., Konte, B., Roussos, P., Giakoumaki, S., Burdick, K. E., Payton, A., Ollier, W., Horan, M., Chiba-Falek, O., Attix, D. K., Need, A. C., Cirulli, E. T., Voineskos, A. N., Stefanis, N. C., Avramopoulos, D., Hatzimanolis, A., Arking, D. E., Smyrnis, N., Bilder, R. M., Freimer, N. A., Cannon, T. D., London, E., Poldrack, R. A., Sabb, F. W., Congdon, E., Conley, E. D., Scult, M. A., Dickinson, D., Straub, R. E., Donohoe, G., Morris, D., Corvin, A., Gill, M., Hariri, A. R., Weinberger, D. R., Pendleton, N., Bitsios, P., Rujescu, D., Lahti, J., Le Hellard, S., Keller, M. C., Andreassen, O. A., Deary, I. J., Glahn, D. C., Malhotra, A. K. & Lencz, T., 1 Mar 2017, In: Molecular Psychiatry. 22, 3, p. 336-345 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    168 Scopus citations
  • Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets

    Lam, M., Trampush, J. W., Yu, J., Knowles, E., Davies, G., Liewald, D. C., Starr, J. M., Djurovic, S., Melle, I., Sundet, K., Christoforou, A., Reinvang, I., DeRosse, P., Lundervold, A. J., Steen, V. M., Espeseth, T., Räikkönen, K., Widen, E., Palotie, A. & Eriksson, J. G. & 45 others, Giegling, I., Konte, B., Roussos, P., Giakoumaki, S., Burdick, K. E., Payton, A., Ollier, W., Chiba-Falek, O., Attix, D. K., Need, A. C., Cirulli, E. T., Voineskos, A. N., Stefanis, N. C., Avramopoulos, D., Hatzimanolis, A., Arking, D. E., Smyrnis, N., Bilder, R. M., Freimer, N. A., Cannon, T. D., London, E., Poldrack, R. A., Sabb, F. W., Congdon, E., Conley, E. D., Scult, M. A., Dickinson, D., Straub, R. E., Donohoe, G., Morris, D., Corvin, A., Gill, M., Hariri, A. R., Weinberger, D. R., Pendleton, N., Bitsios, P., Rujescu, D., Lahti, J., Le Hellard, S., Keller, M. C., Andreassen, O. A., Deary, I. J., Glahn, D. C., Malhotra, A. K. & Lencz, T., 28 Nov 2017, In: Cell Reports. 21, 9, p. 2597-2613 17 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    82 Scopus citations
  • Large-Scale Identification of Common Trait and Disease Variants Affecting Gene Expression

    CommonMind Consortium, 1 Jun 2017, In: American Journal of Human Genetics. 100, 6, p. 885-894 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    51 Scopus citations
  • Minepath.org: A free interactive pathway analysis web server

    Koumakis, L., Roussos, P. & Potamias, G., 3 Jul 2017, In: Nucleic Acids Research. 45, W1, p. W116-W121

    Research output: Contribution to journalArticlepeer-review

    Open Access
    5 Scopus citations
  • Open chromatin profiling of human postmortem brain infers functional roles for non-coding schizophrenia loci

    Fullard, J. F., Giambartolomei, C., Hauberg, M. E., Xu, K., Voloudakis, G., Shao, Z., Bare, C., Dudley, J. T., Mattheisen, M., Robakis, N. K., Haroutunian, V. & Roussos, P., 15 May 2017, In: Human Molecular Genetics. 26, 10, p. 1942-1951 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    56 Scopus citations
  • Practical Guidelines for High-Resolution Epigenomic Profiling of Nucleosomal Histones in Postmortem Human Brain Tissue

    Kundakovic, M., Jiang, Y., Kavanagh, D. H., Dincer, A., Brown, L., Pothula, V., Zharovsky, E., Park, R., Jacobov, R., Magro, I., Kassim, B., Wiseman, J., Dang, K., Sieberts, S. K., Roussos, P., Fromer, M., Harris, B., Lipska, B. K., Peters, M. A. & Sklar, P. & 1 others, Akbarian, S., 15 Jan 2017, In: Biological Psychiatry. 81, 2, p. 162-170 9 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    37 Scopus citations
  • Striatal H3K27 Acetylation Linked to Glutamatergic Gene Dysregulation in Human Heroin Abusers Holds Promise as Therapeutic Target

    Egervari, G., Landry, J., Callens, J., Fullard, J. F., Roussos, P., Keller, E. & Hurd, Y. L., 1 Apr 2017, In: Biological Psychiatry. 81, 7, p. 585-594 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    72 Scopus citations
  • The methyltransferase SETDB1 regulates a large neuron-specific topological chromatin domain

    Jiang, Y., Loh, Y. H. E., Rajarajan, P., Hirayama, T., Liao, W., Kassim, B. S., Javidfar, B., Hartley, B. J., Kleofas, L., Park, R. B., Labonte, B., Ho, S. M., Chandrasekaran, S., Do, C., Ramirez, B. R., Peter, C. J., Julia, T. C. W., Safaie, B. M., Morishita, H. & Roussos, P. & 7 others, Nestler, E. J., Schaefer, A., Tycko, B., Brennand, K. J., Yagi, T., Shen, L. & Akbarian, S., 1 Aug 2017, In: Nature Genetics. 49, 8, p. 1239-1250 12 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    113 Scopus citations
  • 2016

    Activity-dependent changes in gene expression in schizophrenia human-induced pluripotent stem cell neurons

    Roussos, P., Guennewig, B., Kaczorowski, D. C., Barry, G. & Brennand, K. J., 1 Nov 2016, In: JAMA Psychiatry. 73, 11, p. 1180-1188 9 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    32 Scopus citations
  • Analyzing the role of MicroRNAs in schizophrenia in the context of common genetic risk variants

    Hauberg, M. E., Roussos, P., Grove, J., Børglum, A. D. & Mattheisen, M., Apr 2016, In: JAMA Psychiatry. 73, 4, p. 369-377 9 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    71 Scopus citations
  • Associations of differential schizotypal dimensions with executive working memory: A moderated-mediation analysis

    Zouraraki, C., Tsaousis, I., Karamaouna, P., Karagiannopoulou, L., Roussos, P., Bitsios, P. & Giakoumaki, S. G., 1 Nov 2016, In: Comprehensive Psychiatry. 71, p. 39-48 10 p.

    Research output: Contribution to journalArticlepeer-review

    7 Scopus citations
  • Cardiometabolic risk loci share downstream cis- and trans-gene regulation across tissues and diseases

    Franzén, O., Ermel, R., Cohain, A., Akers, N. K., Di Narzo, A., Talukdar, H. A., Foroughi-Asl, H., Giambartolomei, C., Fullard, J. F., Sukhavasi, K., Köks, S., Gan, L. M., Giannarelli, C., Kovacic, J. C., Betsholtz, C., Losic, B., Michoel, T., Hao, K., Roussos, P. & Skogsberg, J. & 3 others, Ruusalepp, A., Schadt, E. E. & Björkegren, J. L. M., 19 Aug 2016, In: Science. 353, 6301, p. 827-830 4 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    194 Scopus citations
  • Cognitive profiles of schizotypal dimensions in a community cohort: Common properties of differential manifestations

    Karagiannopoulou, L., Karamaouna, P., Zouraraki, C., Roussos, P., Bitsios, P. & Giakoumaki, S. G., 20 Oct 2016, In: Journal of Clinical and Experimental Neuropsychology. 38, 9, p. 1050-1063 14 p.

    Research output: Contribution to journalArticlepeer-review

    17 Scopus citations
  • Genetic influences on schizophrenia and subcortical brain volumes: Large-scale proof of concept

    Psychosis Endophenotypes International Consortium, 23 Feb 2016, In: Nature Neuroscience. 19, 3, p. 420-431 12 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    169 Scopus citations
  • Genome-wide12 DNA methylation profiling in the superior temporal gyrus reveals epigenetic signatures associated with Alzheimer's disease

    Watson, C. T., Roussos, P., Garg, P., Ho, D. J., Azam, N., Katsel, P. L., Haroutunian, V. & Sharp, A. J., 19 Jan 2016, In: Genome Medicine. 8, 1, 5.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    139 Scopus citations