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PROFESSOR Medicine, Hematology and Medical Oncology PROFESSOR Urology
Biography
Dr. Bhardwaj's research focuses on the study of dendritic cells, which serve a crucial function as sentinels of the immune system. They are potent antigen-presenting cells which integrate microbe sensing, antigen display, and context-dependent instruction to T cells, to direct the appropriate type of immune response. The Bhardwaj lab focuses on combining fundamental research in dendritic cell biology with innovative translational and clinical approaches. We are thus investigating specialized cytokine secretion, antigen presentation, T cell skewing, interactions with NK cells, and optimal methods of antigen delivery for vaccines using dendritic cells, in HIV, autoimmunity and cancer. For more information, see http://icahn.mssm.edu/research/labs/bhardwaj-laboratory http://icahn.mssm.edu/research/labs/bhardwaj-laboratory
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Dissecting myeloid cell-mediated resistance to immune checkpoint blockade in bladder cancer
Bhardwaj, N., Galsky, M., Galsky, M., Zhu, J. J., Galsky, M. M. & Zhu, J.
1/04/20 → 31/03/23
Project: Research
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Cancer Research Institute Grants
Slingluff, C. L. C. L., Hamouda, D. D., Gaughan, E. E., Puzanov, I. I., Shirai, K. K., Kruse, M. M., Lowe, M. M. & Bhardwaj, N.
1/01/20 → …
Project: Research
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Cancer Research Institute Grants
Slingluff, C. L. C. L., Hamouda, D. D., Gaughan, E. E., Puzanov, I. I., Shirai, K. K., Kruse, M. M., Lowe, M. M. & Bhardwaj, N.
1/01/17 → …
Project: Research
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Association between Incidental Pelvic Inflammation and Aggressive Prostate Cancer
Chakravarty, D., Ratnani, P., Huang, L., Dovey, Z., Sobotka, S., Berryhill, R., Merisaari, H., Al Shaarani, M., Rai, R., Jambor, I., Yadav, K. K., Mittan, S., Parekh, S., Kodysh, J., Wagaskar, V., Brody, R., Cordon-Cardo, C., Rykunov, D., Reva, B., Davicioni, E., & 4 others, 1 Jun 2022, In: Cancers. 14, 11, 2734.Research output: Contribution to journal › Article › peer-review
Open Access -
Author Correction: Neoadjuvant clinical trials provide a window of opportunity for cancer drug discovery (Nature Medicine, (2022), 28, 4, (626-629), 10.1038/s41591-022-01681-x)
Marron, T. U., Galsky, M. D., Taouli, B., Fiel, M. I., Ward, S., Kim, E., Yankelevitz, D., Doroshow, D., Guttman-Yassky, E., Ungar, B., Mehandru, S., Golas, B. J., Labow, D., Sfakianos, J., Nair, S. S., Chakravarty, D., Buckstein, M., Song, X., Kenigsberg, E., Gnjatic, S., & 6 others, Aug 2022, In: Nature Medicine. 28, 8, p. 1723 1 p.Research output: Contribution to journal › Comment/debate
Open Access -
Dark genome, bright ideas: Recent approaches to harness transposable elements in immunotherapies
Reid Cahn, A., Bhardwaj, N. & Vabret, N., 8 Aug 2022, In: Cancer Cell. 40, 8, p. 792-797 6 p.Research output: Contribution to journal › Comment/debate
Open Access -
Exhausted T cell phenotypes depend on TCR signal strength
Tran, M. A. & Bhardwaj, N., Apr 2022, In: Nature Reviews Immunology. 22, 4, p. 206 1 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Lung Cancer and Severe Acute Respiratory Syndrome Coronavirus 2 Infection: Identifying Important Knowledge Gaps for Investigation
Rolfo, C., Meshulami, N., Russo, A., Krammer, F., García-Sastre, A., Mack, P. C., Gomez, J. E., Bhardwaj, N., Benyounes, A., Sirera, R., Moore, A., Rohs, N., Henschke, C. I., Yankelevitz, D., King, J., Shyr, Y., Bunn, P. A., Minna, J. D. & Hirsch, F. R., Feb 2022, In: Journal of Thoracic Oncology. 17, 2, p. 214-227 14 p.Research output: Contribution to journal › Review article › peer-review
Open Access10 Scopus citations
Press / Media
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Cell BioEngines Enters into Licensing Agreement with Icahn School of Medicine at Mount Sinai
Sreekumar Balanalan, Sreekumar Balan & Nina Bhardwaj
27/01/23
1 item of Media coverage
Press/Media
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Cell BioEngines Enters into an Exclusive Worldwide Agreement to Develop and Commercialize Potent Immune Cell States to Cure Cancer
Sreekumar Balanalan, Sreekumar Balan & Nina Bhardwaj
25/01/23 → 26/01/23
93 items of Media coverage
Press/Media
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Immune cell that helps kill bladder cancer tumors: Research
12/09/22 → 3/01/23
13 items of Media coverage
Press/Media
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Cancer vaccines are showing promise. Here’s how they work.
22/12/22 → 23/12/22
2 items of Media coverage
Press/Media