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ASSOCIATE PROFESSOR | Cell, Developmental & Regenerative Biology
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Research Topics http://www.mountsinai.org/vgn-ext-templating/FapServlet?tab=far&rt=Cardiovascular&kw=&loc=&ips=&hrs=&g=&ln=&fn=&vgnextoid=276c2ed69fb76210VgnVCM1000003242020aRCRD&sitename=MSMC&fpa=&inst= Cardiovascular http://www.mountsinai.org/vgn-ext-templating/FapServlet?tab=far&rt=Cellular+Differentiation&kw=&loc=&ips=&hrs=&g=&ln=&fn=&vgnextoid=276c2ed69fb76210VgnVCM1000003242020aRCRD&sitename=MSMC&fpa=&inst= Cellular Differentiation http://www.mountsinai.org/vgn-ext-templating/FapServlet?tab=far&rt=Developmental+Biology&kw=&loc=&ips=&hrs=&g=&ln=&fn=&vgnextoid=276c2ed69fb76210VgnVCM1000003242020aRCRD&sitename=MSMC&fpa=&inst= Developmental Biology http://www.mountsinai.org/vgn-ext-templating/FapServlet?tab=far&rt=Molecular+Biology&kw=&loc=&ips=&hrs=&g=&ln=&fn=&vgnextoid=276c2ed69fb76210VgnVCM1000003242020aRCRD&sitename=MSMC&fpa=&inst= Molecular Biology http://www.mountsinai.org/vgn-ext-templating/FapServlet?tab=far&rt=Regeneration&kw=&loc=&ips=&hrs=&g=&ln=&fn=&vgnextoid=276c2ed69fb76210VgnVCM1000003242020aRCRD&sitename=MSMC&fpa=&inst= Regeneration http://www.mountsinai.org/vgn-ext-templating/FapServlet?tab=far&rt=Stem+Cells&kw=&loc=&ips=&hrs=&g=&ln=&fn=&vgnextoid=276c2ed69fb76210VgnVCM1000003242020aRCRD&sitename=MSMC&fpa=&inst= Stem Cells Training Areas http://www.mountsinai.org/vgn-ext-templating/FapServlet?tab=far&ta=Biophysics+and+Systems+Pharmacology+[BSP]&kw=&loc=&ips=&hrs=&g=&ln=&fn=&vgnextoid=276c2ed69fb76210VgnVCM1000003242020aRCRD&sitename=MSMC&fpa=&inst= Biophysics and Systems Pharmacology [BSP] http://www.mountsinai.org/vgn-ext-templating/FapServlet?tab=far&ta=Developmental+and+Stem+Cell+Biology+[DSCB]&kw=&loc=&ips=&hrs=&g=&ln=&fn=&vgnextoid=276c2ed69fb76210VgnVCM1000003242020aRCRD&sitename=MSMC&fpa=&inst= Developmental and Stem Cell Biology [DSCB] Education B.A., Swiss Federal Institute of Technology Zurich (ETHZ) postdoc, McEwen Centre for Regenerative Medicine Toronto Ph.D., Swiss Institute for Experimental Cancer Research (ISREC) Biography In the Dubois lab we are interested in understanding human heart development and disease. We are using the human pluripotent stem cell (hPSC) model to investigate the cellular and molecular mechanisms of cell fate specification and disease in the early human heart. For more detailed information please visit us on our lab website http://research.mssm.edu/duboislab/
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A Systemic Selective Modified mRNA Delivery Platform for Preventing Chemotherapy-Induced Cardiotoxicity
Yoo, J., Mainkar, G., Ghiringhelli, M., Santos, B. G. D., Żak, M. M., Kaur, K., Kurian, A. A., Adjmi, M., Sharon, S., Markopoulou, E., Žigová, L., Hirsch, D., Pessin, S., Hanan, R., Abreu, J. L. E., Brisnovali, N., Dubois, N., Goedeke, L., Shen, M. & Zangi, L., 18 Feb 2026, In: Advanced Science. 13, 10, e10543.Research output: Contribution to journal › Article › peer-review
Open Access -
Circulating Extracellular Vesicles in the Pathogenesis of Heart Failure in Patients With Chronic Kidney Disease
Li, X., Raisinghani, N., Gallinat, A., Santos-Gallego, C. G., Zhang, S., La Salvia, S., Yoon, S., Yavuz, H., Phan, A., Shao, A., Harding, M., Sachs, D., Levy, C. J., Vasavada, R., Dubois, N. C., Erdbrügger, U. & Sahoo, S., 13 Jan 2026, In: Circulation. 153, 2, p. 94-114 21 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
A rapid and robust protocol for generating loss-of-function alleles in pluripotent stem cells
Baljinnyam, E., Grisanti, L., Tattari, S., Pedicone, C., Shewale, B., Dubois, N., Goate, A. M., Kerr, W. G. & Marro, S. G., 19 Sep 2025, In: STAR Protocols. 6, 3, 103916.Research output: Contribution to journal › Article › peer-review
Open Access -
Molecular Regulation of Cardiomyocyte Maturation
Shewale, B., Ebrahim, T., Samal, A. & Dubois, N., Dec 2025, In: Current Cardiology Reports. 27, 1, 32.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
Novel Artificial 5′UTR Increase Modified mRNA Translation When Injected into Mouse Heart
Kurian, A. A., Ghiringhelli, M., Shalom, E., Mainkar, G., Żak, M. M., Adjmi, M., Downey, J., Yoon, S., Dubois, N., Swirski, F. K. & Zangi, L., Apr 2025, In: Pharmaceutics. 17, 4, 490.Research output: Contribution to journal › Article › peer-review
Open Access
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Study Findings on miRNA-Based Therapy Are Outlined in Reports from Icahn School of Medicine at Mount Sinai (Circulating Extracellular Vesicles in the Pathogenesis of Heart Failure in Patients with Chronic Kidney Disease)
Vasavada, R., DuBois, N., Sachs, D., Dogra, N. & Levy, C.
14/11/25
1 item of Media coverage
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Center on Budget & Policy Priorities: State and Local Policymakers Should Advance Policies Prioritizing Stability and Dignity to Solve Homelessness
7/08/25
1 item of Media coverage
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Icahn School of Medicine at Mount Sinai Researchers Discuss Research in Science (Multiscale mapping of transcriptomic signatures for cardiotoxic drugs)
DuBois, N., Birtwistle, M., Hansen, J., Sebra, R., Azeloglu, E., Sobie, E., Iyengar, S., Schaniel, C., Goldfarb, J., Gallo, J. & Chen, Y.-B.
2/10/24
1 item of Media coverage
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Reports on Pharmacology Findings from Icahn School of Medicine at Mount Sinai Provide New Insights (Predicting individual-specific cardiotoxicity responses induced by tyrosine kinase inhibitors)
DuBois, N., Birtwistle, M., Azeloglu, E., Sobie, E., Iyengar, S. & Schaniel, C.
21/04/23
1 item of Media coverage
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