Research output per year
Research output per year
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ASSOCIATE PROFESSOR | Cell, Developmental & Regenerative Biology
Biography
Research Topics http://www.mountsinai.org/vgn-ext-templating/FapServlet?tab=far&rt=Cardiovascular&kw=&loc=&ips=&hrs=&g=&ln=&fn=&vgnextoid=276c2ed69fb76210VgnVCM1000003242020aRCRD&sitename=MSMC&fpa=&inst= Cardiovascular http://www.mountsinai.org/vgn-ext-templating/FapServlet?tab=far&rt=Cellular+Differentiation&kw=&loc=&ips=&hrs=&g=&ln=&fn=&vgnextoid=276c2ed69fb76210VgnVCM1000003242020aRCRD&sitename=MSMC&fpa=&inst= Cellular Differentiation http://www.mountsinai.org/vgn-ext-templating/FapServlet?tab=far&rt=Developmental+Biology&kw=&loc=&ips=&hrs=&g=&ln=&fn=&vgnextoid=276c2ed69fb76210VgnVCM1000003242020aRCRD&sitename=MSMC&fpa=&inst= Developmental Biology http://www.mountsinai.org/vgn-ext-templating/FapServlet?tab=far&rt=Molecular+Biology&kw=&loc=&ips=&hrs=&g=&ln=&fn=&vgnextoid=276c2ed69fb76210VgnVCM1000003242020aRCRD&sitename=MSMC&fpa=&inst= Molecular Biology http://www.mountsinai.org/vgn-ext-templating/FapServlet?tab=far&rt=Regeneration&kw=&loc=&ips=&hrs=&g=&ln=&fn=&vgnextoid=276c2ed69fb76210VgnVCM1000003242020aRCRD&sitename=MSMC&fpa=&inst= Regeneration http://www.mountsinai.org/vgn-ext-templating/FapServlet?tab=far&rt=Stem+Cells&kw=&loc=&ips=&hrs=&g=&ln=&fn=&vgnextoid=276c2ed69fb76210VgnVCM1000003242020aRCRD&sitename=MSMC&fpa=&inst= Stem Cells Training Areas http://www.mountsinai.org/vgn-ext-templating/FapServlet?tab=far&ta=Biophysics+and+Systems+Pharmacology+[BSP]&kw=&loc=&ips=&hrs=&g=&ln=&fn=&vgnextoid=276c2ed69fb76210VgnVCM1000003242020aRCRD&sitename=MSMC&fpa=&inst= Biophysics and Systems Pharmacology [BSP] http://www.mountsinai.org/vgn-ext-templating/FapServlet?tab=far&ta=Developmental+and+Stem+Cell+Biology+[DSCB]&kw=&loc=&ips=&hrs=&g=&ln=&fn=&vgnextoid=276c2ed69fb76210VgnVCM1000003242020aRCRD&sitename=MSMC&fpa=&inst= Developmental and Stem Cell Biology [DSCB] Education B.A., Swiss Federal Institute of Technology Zurich (ETHZ) postdoc, McEwen Centre for Regenerative Medicine Toronto Ph.D., Swiss Institute for Experimental Cancer Research (ISREC) Biography In the Dubois lab we are interested in understanding human heart development and disease. We are using the human pluripotent stem cell (hPSC) model to investigate the cellular and molecular mechanisms of cell fate specification and disease in the early human heart. For more detailed information please visit us on our lab website http://research.mssm.edu/duboislab/
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Collaborations and top research areas from the last five years
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Multiscale mapping of transcriptomic signatures for cardiotoxic drugs
Hansen, J., Xiong, Y., Siddiq, M. M., Dhanan, P., Hu, B., Shewale, B., Yadaw, A. S., Jayaraman, G., Tolentino, R. E., Chen, Y., Martinez, P., Beaumont, K. G., Sebra, R., Vidovic, D., Schürer, S. C., Goldfarb, J., Gallo, J. M., Birtwistle, M. R., Sobie, E. A. & Azeloglu, E. U. & 5 others, , Dec 2024, In: Nature Communications. 15, 1, 7968.Research output: Contribution to journal › Article › peer-review
Open Access -
Transient stabilization of human cardiovascular progenitor cells from human pluripotent stem cells in vitro reflects stage-specific heart development in vivo
Bolesani, E., Bornhorst, D., Iyer, L. M., Zawada, D., Friese, N., Morgan, M., Lange, L., Gonzalez, D. M., Schrode, N., Leffler, A., Wunder, J., Franke, A., Drakhlis, L., Sebra, R., Schambach, A., Goedel, A., Dubois, N. C., Dobreva, G., Moretti, A. & Zelaráyan, L. C. & 2 others, , 1 Jul 2024, In: Cardiovascular Research. 120, 11, p. 1295-1311 17 p.Research output: Contribution to journal › Article › peer-review
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An atlas of lamina-associated chromatin across twelve human cell types reveals an intermediate chromatin subtype
Shah, P. P., Keough, K. C., Gjoni, K., Santini, G. T., Abdill, R. J., Wickramasinghe, N. M., Dundes, C. E., Karnay, A., Chen, A., Salomon, R. E. A., Walsh, P. J., Nguyen, S. C., Whalen, S., Joyce, E. F., Loh, K. M., Dubois, N., Pollard, K. S. & Jain, R., Dec 2023, In: Genome Biology. 24, 1, 16.Research output: Contribution to journal › Article › peer-review
Open Access21 Scopus citations -
Conditional blastocyst complementation of a defective Foxa2 lineage efficiently promotes the generation of the whole lung
Miura, A., Sarmah, H., Tanaka, J., Hwang, Y., Sawada, A., Shimamura, Y., Otoshi, T., Kondo, Y., Fang, Y., Shimizu, D., Ninish, Z., Suer, J. L., Dubois, N. C., Davis, J., Toyooka, S., Wu, J., Que, J., Hawkins, F. J., Lin, C. S. & Mori, M., 2023, In: eLife. 12, e86105.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Extracellular Vesicle-Encapsulated Adeno-Associated Viruses for Therapeutic Gene Delivery to the Heart
Li, X., La Salvia, S., Liang, Y., Adamiak, M., Kohlbrenner, E., Jeong, D., Chepurko, E., Ceholski, D., Lopez-Gordo, E., Yoon, S., Mathiyalagan, P., Agarwal, N., Jha, D., Lodha, S., Daaboul, G., Phan, A., Raisinghani, N., Zhang, S., Zangi, L. & Gonzalez-Kozlova, E. & 4 others, , 1 Aug 2023, In: Circulation. 148, 5, p. 405-425 21 p.Research output: Contribution to journal › Article › peer-review
Open Access19 Scopus citations
Press/Media
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Icahn School of Medicine at Mount Sinai Researchers Discuss Research in Science (Multiscale mapping of transcriptomic signatures for cardiotoxic drugs)
DuBois, N., Birtwistle, M., Hansen, J., Sebra, R., Azeloglu, E., Sobie, E., Iyengar, S., Schaniel, C., Goldfarb, J., Gallo, J. & Chen, Y.-B.
2/10/24
1 item of Media coverage
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Reports on Pharmacology Findings from Icahn School of Medicine at Mount Sinai Provide New Insights (Predicting individual-specific cardiotoxicity responses induced by tyrosine kinase inhibitors)
DuBois, N., Birtwistle, M., Azeloglu, E., Sobie, E., Iyengar, S. & Schaniel, C.
21/04/23
1 item of Media coverage
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Mount Sinai Develops Method to Advance Maturation of Human Pluripotent Stem Cell-Derived Heart Cells
10/04/22
1 item of Media coverage
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New Method Generates Mature Human Heart Cells from Stem Cells
8/04/22
1 item of Media coverage
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Mount Sinai Develops Method to Advance Maturation of Human Pluripotent Stem Cell-Derived Heart Cells
7/04/22
1 item of Media coverage
Press/Media