Research output per year
Research output per year
Personal profile
Headline
PROFESSOR | Neurology PROFESSOR | Pediatrics PROFESSOR | Genetics and Genomic Sciences
Biography
Specialty http://icahn.mssm.edu/vgn-ext-templating/FapServlet?tab=fad&sp=Pediatric+Neurology&kw=&loc=&ips=&hrs=&g=&ln=&fn=&vgnextoid=24fc8af68fc17210VgnVCM1000003242020aRCRD&sitename=MSSM&fpa=true&inst= Pediatric Neurology http://icahn.mssm.edu/vgn-ext-templating/FapServlet?tab=fad&sp=Pediatrics&kw=&loc=&ips=&hrs=&g=&ln=&fn=&vgnextoid=24fc8af68fc17210VgnVCM1000003242020aRCRD&sitename=MSSM&fpa=true&inst= Pediatrics Certifications American Board of Pediatrics Psychiatry & Neurology Research Topics http://icahn.mssm.edu/vgn-ext-templating/FapServlet?tab=far&rt=Behavior&kw=&loc=&ips=&hrs=&g=&ln=&fn=&vgnextoid=24fc8af68fc17210VgnVCM1000003242020aRCRD&sitename=MSSM&fpa=true&inst= Behavior http://icahn.mssm.edu/vgn-ext-templating/FapServlet?tab=far&rt=Parkinson%27s+Disease&kw=&loc=&ips=&hrs=&g=&ln=&fn=&vgnextoid=24fc8af68fc17210VgnVCM1000003242020aRCRD&sitename=MSSM&fpa=true&inst= Parkinson's Disease Training Areas http://icahn.mssm.edu/vgn-ext-templating/FapServlet?tab=far&ta=Genetics+and+Genomic+Sciences+[GGS]&kw=&loc=&ips=&hrs=&g=&ln=&fn=&vgnextoid=24fc8af68fc17210VgnVCM1000003242020aRCRD&sitename=MSSM&fpa=true&inst= Genetics and Genomic Sciences [GGS] http://icahn.mssm.edu/vgn-ext-templating/FapServlet?tab=far&ta=Neuroscience+[NEU]&kw=&loc=&ips=&hrs=&g=&ln=&fn=&vgnextoid=24fc8af68fc17210VgnVCM1000003242020aRCRD&sitename=MSSM&fpa=true&inst= Neuroscience [NEU] Education MD, New York Hospital Cornell University Med Ctr Internship, Pediatrics New York Presbyterian Hospital Residency, Pediatrics New York Presbyterian Hospital Residency, Neurology New York Presbyterian Hospital Fellowship, Metabolism Cornell Medical Center Fellowship, Pediatrics/Neurology New York Presbyterian Hospital
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Collaborations and top research areas from the last five years
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BCI-838, an orally active mGluR2/3 receptor antagonist pro-drug, rescues learning behavior deficits in the PS19 MAPTP301S mouse model of tauopathy
Perez-Garcia, G., Bicak, M., Haure-Mirande, J. V., Perez, G. M., Otero-Pagan, A., Gama Sosa, M. A., De Gasperi, R., Sano, M., Barlow, C., Gage, F. H., Readhead, B., Ehrlich, M. E., Gandy, S. & Elder, G. A., 16 Feb 2023, In: Neuroscience Letters. 797, 137080.Research output: Contribution to journal › Article › peer-review
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Correction: miR155, TREM2, INPP5D: Disease stage and cell-type are essential considerations when targeting clinical interventions based on mouse models of Alzheimer’s amyloidopathy (Journal of Neuroinflammation, (2023), 20, 1, (214), 10.1186/s12974-023-02895-7)
Gandy, S. & Ehrlich, M. E., Dec 2023, In: Journal of Neuroinflammation. 20, 1, 288.Research output: Contribution to journal › Comment/debate
Open Access -
Effect of Aging and a Dual Orexin Receptor Antagonist on Sleep Architecture and Non-REM Oscillations Including an REM Behavior Disorder Phenotype in the PS19 Mouse Model of Tauopathy
Kam, K., Vetter, K., Tejiram, R. A., Pettibone, W. D., Shim, K., Audrain, M., Yu, L., Daehn, I. S., Ehrlich, M. E. & Varga, A. W., 21 Jun 2023, In: Journal of Neuroscience. 43, 25, p. 4738-4749 12 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Genetic architecture of plasma Alzheimer disease biomarkers
Bradley, J., Gorijala, P., Schindler, S. E., Sung, Y. J., Ances, B., Ertekin-Taner, N., Younkin, S., Golde, T., Price, N., Bennett, D., Gaiteri, C., De Jager, P., Zhang, B., Schadt, E., Ehrlich, M., Haroutunian, V., Gandy, S., Iijima, K., Noggle, S., Mangravite, L., & 2 others, 1 Aug 2023, In: Human Molecular Genetics. 32, 15, p. 2532-2543 12 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Microglial INPP5D limits plaque formation and glial reactivity in the PSAPP mouse model of Alzheimer's disease
Castranio, E. L., Hasel, P., Haure-Mirande, J. V., Ramirez Jimenez, A. V., Hamilton, B. W., Kim, R. D., Glabe, C. G., Wang, M., Zhang, B., Gandy, S., Liddelow, S. A. & Ehrlich, M. E., Jun 2023, In: Alzheimer's and Dementia. 19, 6, p. 2239-2252 14 p.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations
Press/Media
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Studies from Icahn School of Medicine at Mount Sinai Yield New Data on Behavior Disorders (Effect of Aging and a Dual Orexin Receptor Antagonist On Sleep Architecture and Non-rem Oscillations Including an Rem Behavior Disorder Phenotype In the ...)
Michelle Ehrlich, Korey Kam & Andrew Varga
24/08/23
1 item of Media coverage
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Ridding Microglia of a MicroRNA Compacts Amyloid, Protects Synapses
Joel Dudley & Michelle Ehrlich
30/06/23
1 item of Media coverage
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Neurologists Answer Questions Patients May Have About New Alzheimer’s Drug Lecanemab
27/01/23
1 item of Media coverage
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In Nasu-Hakola Disease, DAP12-Deficient Microglia Kick Repair into Overdrive
27/01/23
1 item of Media coverage
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New Findings Reported from Icahn School of Medicine at Mount Sinai Describe Advances in Alzheimer Disease [Dual-specificity Protein Phosphatase 4 (Dusp4) Overexpression Improves Learning Behavior Selectively In Female 5xfad Mice, and Reduces ...]
Qian Wang, Minghui Wang, Samuel Gandy, Noam Beckmann, Eric Schadt & Michelle Ehrlich
16/01/23
1 item of Media coverage
Press/Media