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PROFESSOR | Medicine, Division of Genomic Medicine
CLINICAL DIRECTOR | Institute for Genomic Health
Biography
Dr. Michael F. Murray was newly appointed in July of 2023 as the Genomic Medicine Division Chief within the Department of Medicine and as the Clinical Director for the Institute for Genomic Health. He is an international expert in using DNA-derived information as a screening tool in clinical care, population health, and public health.
Prior to joining Mount Sinai Health System and Icahn School of Medicine he had the opportunity to lead cutting-edge clinical integration efforts in genomic medicine at Harvard, Geisinger, and Yale. These efforts were aimed at: Bridging the interpretation of genetic variants to the implementation of clinical care. Creating health system infrastructure for genomic risk screening and genomic diagnosis. Preparing clinicians across large health systems for the management of genomic information. Designing and executing efforts aimed at fostering patient use of actionable genomic information. And creating novel clinical strategies for “sequence once and interpret many times” workflows.
He received his medical degree from Pennsylvania State University School of Medicine in Hershey Pennsylvania. Following medical school, he went on to residency training in Internal Medicine at the Cleveland Clinic. He later completed two training fellowships first in Infectious Diseases at the University of Pennsylvania and then in Clinical Genetics Training at Harvard Medical School.
He was a community practice primary care provider for a time, and he has since held positions as a visiting scientist at the MIT Cancer Center, Clinical Chief of Genetics at Brigham and Women’s Hospital, Director of Clinical Genomics at Geisinger Health System, and Director of Clinical Operations in the Center for Genomic Health at Yale New Haven Health System. He has been on the faculty of Harvard Medical School, Geisinger Commonwealth School of Medicine, and Yale School of Medicine.
He currently serves as a member of the Board of Directors for the American College of Medical Genetics and Genomics (ACMG). He is on the Editorial Board for BMC Global and Public Health. He serves as an advisor to the National African American Precision Medicine Project.
Along with Drs. Mark Babyatsky and Monica Giovanni, he was the co-editor of “Clinical Genomics: Practical Applications for Adult Patient Care” (published by McGraw Hill). He has authored over 100 peer-reviewed publications.
He is nationally known for his work in Genomic Medicine Education. He was the Founding Director of the Combined Residency in Internal Medicine and Medical Genetics, Brigham and Women’s Hospital, and was the Director of the “Genetic Basis of Adult Medicine” an Annual CME Course at Harvard Medical School.
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Collaborations and top research areas from the last five years
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Healthcare professionals’ experiences returning monogenic, polygenic, and integrated risk results in the eMERGE study
Suckiel, S. A., Golfinopoulos, L., Scherr, C. L., Boyd, B. M., Chung, W. K., Hakonarson, H., Holm, I. A., Kullo, I. J., Limdi, N. A., Murray, M. F., Myers, M. F., Prows, C. A., Sabatello, M., Wiesner, G. L., Kenny, E. E. & Abul-Husn, N. S., 15 Jan 2026, In: Human Genetics and Genomics Advances. 7, 1, 100554.Research output: Contribution to journal › Article › peer-review
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Just-in-time education to prepare clinicians for genomics
Hoffman, D. R., Iverson, A. A., Abul-Husn, N. S., Kenny, E. E. & Murray, M. F., 2026, (Accepted/In press) In: Trends in Genetics.Research output: Contribution to journal › Short survey › peer-review
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PAD-associated Genetic Variants are More Strongly Associated with Surgical Intervention than Premature Onset
Hu, J., Alameddine, D., Wang, H., Mani, A., Scharfe, C., Jiang, Y. H., Murray, M. F., Chaar, C. I. O. & DeWan, A. T., Dec 2026, In: Journal of Cardiovascular Translational Research. 19, 1, 14.Research output: Contribution to journal › Article › peer-review
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Genetics of interstitial lung diseases: a state-of-the-art review
Ng, N., Molina-Molina, M., Adegunsoye, A., Borie, R., Newton, C. A., Raby, B., Zhang, D., Padilla, M., Crestani, B., Horwitz, M. S., Keel, S., Murray, M. F., Stergachis, A. B., Knight, S., Garcia, C. K., Wain, L. V. & Raghu, G., 2025, In: European Respiratory Journal. 66, 3, 2500788.Research output: Contribution to journal › Review article › peer-review
Open Access2 Scopus citations -
Rare germline variants in cancer-relevant genes are associated with breast cancer risk in young women with high-risk family history
Rozenblit, M., Qing, T., Ye, Y., Zhao, H., Hofstatter, E., Singh, V., Reisenbichler, E., Murray, M. & Pusztai, L., Jan 2025, In: Breast Cancer Research and Treatment. 209, 1, p. 21-26 6 p.Research output: Contribution to journal › Article › peer-review
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