Research output per year
Research output per year
Personal profile
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ASSISTANT PROFESSOR | Pharmacological Sciences
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Dive into the research topics where Michael Lazarus is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Allosteric Inhibition of PKMYT1 Induces a Unique, Inactive ATP Binding Site Conformation
Herrington, N. B., Khamrui, S., Zhao, Y., Lansiquot, C., Wu, R., Pandey, G., Lazarus, M. B. & Schlessinger, A., 17 Jun 2026, In: Journal of the American Chemical Society. 148, 23, p. 24274-24286 13 p.Research output: Contribution to journal › Article › peer-review
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Correction to “Characterization, Structure, and Inhibition of the Human Succinyl-CoA:glutarate-CoA Transferase, a Putative Genetic Modifier of Glutaric Aciduria Type 1”
Wu, R., Khamrui, S., Dodatko, T., Leandro, J., Sabovic, A., Violante, S., Cross, J. R., Marsan, E., Kumar, K., DeVita, R. J., Lazarus, M. B. & Houten, S. M., 21 Nov 2025, In: ACS Chemical Biology. 20, 11, p. 2846 1 p.Research output: Contribution to journal › Comment/debate
Open Access -
Characterization, Structure, and Inhibition of the Human Succinyl-CoA:glutarate-CoA Transferase, a Putative Genetic Modifier of Glutaric Aciduria Type 1
Wu, R., Khamrui, S., Dodatko, T., Leandro, J., Sabovic, A., Violante, S., Cross, J. R., Marsan, E., Kumar, K., DeVita, R. J., Lazarus, M. B. & Houten, S. M., 19 Jul 2024, In: ACS Chemical Biology. 19, 7, p. 1544-1553 10 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Structural insights into RNA cleavage by a novel family of bacterial RNases
Wu, R., Ingle, S., Barnes, S. A., Dahlin, H. R., Khamrui, S., Xiang, Y., Shi, Y., Bechhofer, D. H. & Lazarus, M. B., 23 Sep 2024, In: Nucleic Acids Research. 52, 17, p. 10705-10716 12 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
A case of hyperlysinemia identified by urine newborn screening
Yeganeh, M., Auray-Blais, C., Maranda, B., Sabovic, A., DeVita, R. J., Lazarus, M. B. & Houten, S. M., Nov 2023, In: JIMD Reports. 64, 6, p. 440-445 6 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations
Press/Media
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New Drug Research Findings from Icahn School of Medicine at Mount Sinai Reported (Structural and biochemical insight into allosteric regulation of the human 2-aminoadipic semialdehyde synthase, a bifunctional enzyme involved in lysine catabolism)
Houten, S., Lazarus, M. & Osman, R.
1/07/26
1 item of Media coverage
Press/Media
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HMN 2026: How AI misses cancer drug target, revealing why lab validation still matters
Schlessinger, A. & Lazarus, M.
19/06/26
1 item of Media coverage
Press/Media
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Study potentially opens a new route to more selective cancer drug design
3/06/26
1 item of Media coverage
Press/Media
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Scientists Uncover Hidden Drug-binding Pocket in Cancer Protein, Highlighting the Power and Limitations of AI Drug Discovery
Schlessinger, A. & Lazarus, M.
3/06/26
5 items of Media coverage
Press/Media