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ASSISTANT PROFESSOR | Psychiatry
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Dive into the research topics where Lotje De Witte is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Investigation of microglia, an immune cell, in Rett syndrome
INTERNATIONAL RETT SYNDROME FOUNDATION
1/01/20 → …
Project: Research
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Investigating the impact of inflammation on brain development using human cerebral organoids.
NATIONAL INSTITUTE OF MENTAL HEALTH
1/04/20 → 31/03/22
Project: Research
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Characterization of HIV-1 Infection in Microglia-Containing Human Cerebral Organoids
Gumbs, S. B. H., van Berlekom, A. B., Kübler, R., Schipper, P. J., Gharu, L., Boks, M. P., Ormel, P. R., Wensing, A. M. J., de Witte, L. D. & Nijhuis, M., Apr 2022, In: Viruses. 14, 4, 829.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
Contribution of Age, Brain Region, Mood Disorder Pathology, and Interindividual Factors on the Methylome of Human Microglia
de Witte, L. D., Wang, Z., Snijders, G. L. J. L., Mendelev, N., Liu, Q., Sneeboer, M. A. M., Boks, M. P. M., Ge, Y. & Haghighi, F., 15 Mar 2022, In: Biological Psychiatry. 91, 6, p. 572-581 10 p.Research output: Contribution to journal › Article › peer-review
Open Access -
De vertaling van genetische risicovarianten naar moleculaire ziektemechanismen
Translated title of the contribution :The translation of genetic risk variants to molecular disease mechanisms Research output: Contribution to journal › Article › peer-review
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Diagnostic model development for schizophrenia based on peripheral blood mononuclear cell subtype-specific expression of metabolic markers
Zaki, J. K., Lago, S. G., Rustogi, N., Gangadin, S. S., Benacek, J., van Rees, G. F., Haenisch, F., Broek, J. A., Suarez-Pinilla, P., Ruland, T., Auyeung, B., Mikova, O., Kabacs, N., Arolt, V., Baron-Cohen, S., Crespo-Facorro, B., Drexhage, H. A., de Witte, L. D., Kahn, R. S., Sommer, I. E., & 2 others, Dec 2022, In: Translational Psychiatry. 12, 1, 457.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Exposure to the Amino Acids Histidine, Lysine, and Threonine Reduces mTOR Activity and Affects Neurodevelopment in a Human Cerebral Organoid Model
van Berlekom, A. B., Kübler, R., Hoogeboom, J. W., Vonk, D., Sluijs, J. A., Pasterkamp, R. J., Middeldorp, J., Kraneveld, A. D., Garssen, J., Kahn, R. S., Hol, E. M., de Witte, L. D. & Boks, M. P., 1 May 2022, In: Nutrients. 14, 10, 2175.Research output: Contribution to journal › Article › peer-review
Open Access
Press/Media
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Mighty MiGA: Microglial Genomic Atlas Zeros in on Causal AD Risk Variants
13/01/22
1 item of Media coverage
Press/Media