Research output per year
Research output per year
Personal profile
Headline
ASSISTANT PROFESSOR Medicine, Pulmonary, Critical Care and Sleep Medicine
Biography
Dr. Kam is interested in understanding how sleep and one of the most common sleep disorders, sleep apnea, contribute to impairments in memory and increased risk for Alzheimer’s disease. In both animal models and humans, Dr. Kam is actively investigating computational methods to measure sleep as well as translational approaches to modulate sleep, a conserved behavior that itself plays a role in the development of neurodegeneration.
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Collaborations and top research areas from the last five years
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High obstructive sleep apnea hypoxic burden associates with reduced locus coeruleus structural integrity on 7T MRI in older adults
Kam, K., Gaggi, N. L., Parekh, A., Valencia, D. I., Quintana Licona, D. A., Hishinuma, S. S., Martillo, K. R., Chu, S. S., Varga, A. W., Hwang, J., Williams, M. K., Mullins, A. E., Tolbert, T. M., Balchandani, P., Iosifescu, D. V., Blessing, E. M., Bubu, O. M., Ayappa, I., Rapoport, D. M. & Morris, L. S. & 1 others, , 1 Mar 2026, In: Sleep. 49, 3, zsaf398.Research output: Contribution to journal › Article › peer-review
Open Access -
Obstructive sleep apnea severity, Alzheimer's disease plasma markers, and CSF brain amyloidosis and tau pathology
Bubu, O. M., Mullins, A. E., Shah, S., Gills, J. L., Kam, K., Parekh, A., Umasabor-Bubu, O. Q., Turner, A. D., Bernard, M., Briggs, A., Ramos-Cejudo, J., Valkanova, E., Mbah, A. K., Pahari, P., Debure, L., Ghuman, M., Boutajangout, A., Williams, N. J., Hwang, J. & Williams, M. K. & 6 others, , Mar 2026, In: Alzheimer's and Dementia. 22, 3, e71270.Research output: Contribution to journal › Article › peer-review
Open Access -
Response to Li and Wang: Slow oscillations and spatial memory: Reflecting on the limited behavioral effects of slow wave sleep-specific CPAP withdrawal
Mullins, A. E., Parekh, A., Kam, K., Valencia, D. I., Schoenholz, R., Fakhoury, A., Castillo, B., Roberts, Z. J., Wickramaratne, S., Tolbert, T. M., Hwang, J., Blessing, E. M., Bubu, O. M., Rapoport, D. M., Ayappa, I., Osorio, R. S. & Varga, A. W., 1 Jan 2026, In: Sleep. 49, 1, zsaf346.Research output: Contribution to journal › Letter › peer-review
Open Access -
White matter microstructure differences in obstructive sleep apnea severity groups assessed by diffusion tensor metrics and biophysical modeling
Figueredo, L. F., Chen, J., Gaggi, N. L., Song, X., Jacobs, T., Silva-Albornoz, G., Pehel, S., Gonzalez, M., Badia, S. G., Rosenzweig, I., Naismith, S. L., Ramos-Cejudo, J., Gills, J., Ayappa, I., Rapoport, D. M., Kam, K., Mullins, A. E., Parekh, A., Varga, A. W. & Bubu, O. M. & 4 others, , Dec 2026, In: Scientific Reports. 16, 1, 11963.Research output: Contribution to journal › Article › peer-review
Open Access -
EEG slow oscillations and overnight spatial navigational memory performance in CPAP-treated obstructive sleep apnea
Mullins, A. E., Parekh, A., Kam, K., Valencia, D. I., Schoenholz, R., Fakhoury, A., Castillo, B., Roberts, Z. J., Wickramaratne, S., Tolbert, T. M., Hwang, J., Blessing, E. M., Bubu, O. M., Rapoport, D. M., Ayappa, I., Osorio, R. S. & Varga, A. W., 1 Aug 2025, In: Sleep. 48, 8Research output: Contribution to journal › Article › peer-review
Open Access
Press/Media
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Studies from Icahn School of Medicine at Mount Sinai Provide New Data on Chemicals and Chemistry (Greater hypoxic burden predicts weaker coordination between brain pulsation and CSF flow on 7T MRI independent of non-hypoxic arousals: ...)
Kam, K., Ayappa, I. & Varga, A.
23/06/26
1 item of Media coverage
Press/Media
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Research Data from Icahn School of Medicine at Mount Sinai Update Understanding of Obstructive Sleep Apnea (High Obstructive Sleep Apnea Hypoxic Burden Associates With Reduced Locus Coeruleus Structural Integrity On 7t Mri In Older Adults)
Iosifescu, D. V., Parekh, A., Kam, K., Morris, L., Ayappa, I., Varga, A. & Balchandani, P.
12/02/26
1 item of Media coverage
Press/Media
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FOR IMMEDIATE RELEASE: Mount Sinai experts present research at SLEEP 2025
Parekh, A., Kam, K., Varga, A. & During, E.
8/06/25
1 item of Media coverage
Press/Media