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ASSOCIATE PROFESSOR | Diagnostic, Molecular and Interventional Radiology, ASSOCIATE PROFESSOR | Neurosurgery
Biography
Ki Sueng Choi, Ph.D., is an Assistant Professor of Radiology and Neurosurgery. His special expertise resides in the functional neuroimaging, integration of multimodal neuroimaging strategies (sMRI, DTI, fMRI), and neuromodulation technologies. His research is focused on the characterizing the structural and functional organization of brain circuits using diffusion tensor imaging and functional MRI for applications in the imaging biomarkers to understand brain mechanism (disease subtypes and treatment effects) and optimizing surgical targeting for deep brain stimulation (DBS) in various psychiatric and neurological disorders including major depressive disorder, obsessive-compulsive disorder, Parkinson’s disease, and Tremor.
Dr. Choi characterized the critical brain network that mediating subcallosal cingulate (SCC) deep brain stimulation antidepressant response with computational subject-specific DBS modeling and developed the prospective target selection algorithm/pipeline/toolbox for SCC DBS using diffusion tractography such as “Connectomic Targeting Approach” that provides a guidance for precise surgical implantation of leads and optimization algorithms for the selection of contacts in long-term stimulation.
Research interests
Brain Imaging, Depression, Diffusion Tensor Imaging, Image Analysis, Magnetic Resonance Imaging, Neuromodulation, Neuroscience, Positron Emission Tomography
Multi-Disciplinary Training Areas
Artificial Intelligence and Emerging Technologies in Medicine [AIET], Neuroscience [NEU]
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Projects
- 1 Finished
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Connectomic Deep Brain Stimulation for Obsessive Compulsive Disorder
Choi, K. S., Figee, M. & Figee, M. M.
NATIONAL INSTITUTE OF MENTAL HEALTH
1/05/21 → 28/02/23
Project: Research
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AI-based dimensional neuroimaging system for characterizing heterogeneity in brain structure and function in major depressive disorder: COORDINATE-MDD consortium design and rationale
Fu, C. H. Y., Erus, G., Fan, Y., Antoniades, M., Arnone, D., Arnott, S. R., Chen, T., Choi, K. S., Fatt, C. C., Frey, B. N., Frokjaer, V. G., Ganz, M., Garcia, J., Godlewska, B. R., Hassel, S., Ho, K., McIntosh, A. M., Qin, K., Rotzinger, S., Sacchet, M. D., & 29 others , Dec 2023, In: BMC Psychiatry. 23, 1, 59.Research output: Contribution to journal › Article › peer-review
Open Access -
Shared and Unique Changes in Brain Connectivity Among Depressed Patients After Remission With Pharmacotherapy Versus Psychotherapy
Dunlop, B. W., Cha, J., Choi, K. S., Rajendra, J. K., Nemeroff, C. B., Craighead, W. E. & Mayberg, H. S., 1 Mar 2023, In: American Journal of Psychiatry. 180, 3, p. 218-229 12 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Co-alteration Network Architecture of Major Depressive Disorder: A Multi-modal Neuroimaging Assessment of Large-scale Disease Effects
Gray, J. P., Manuello, J., Alexander-Bloch, A. F., Leonardo, C., Franklin, C., Choi, K. S., Cauda, F., Costa, T., Blangero, J., Glahn, D. C., Mayberg, H. S. & Fox, P. T., 2022, (Accepted/In press) In: Neuroinformatics.Research output: Contribution to journal › Article › peer-review
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Deep Brain Stimulation for Depression
Figee, M., Riva-Posse, P., Choi, K. S., Bederson, L., Mayberg, H. S. & Kopell, B. H., Jul 2022, In: Neurotherapeutics. 19, 4, p. 1229-1245 17 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Dynamic Oscillations Evoked by Subcallosal Cingulate Deep Brain Stimulation
Tiruvadi, V., Choi, K. S., Gross, R. E., Butera, R., Jirsa, V. & Mayberg, H., 23 Feb 2022, In: Frontiers in Neuroscience. 16, 768355.Research output: Contribution to journal › Article › peer-review
Open Access