Biochemistry, Genetics and Molecular Biology
Methyltransferase
100%
Protein Catabolism
72%
Lysine
65%
Small Molecule
59%
Epigenetics
56%
Cancer Cell
43%
EZH2
39%
Arginine
35%
Methylation
33%
Histone
29%
Polycomb Repressive Complex 2
26%
Transcription Factor EZH2
24%
Mouse
20%
P53
18%
Ligase
18%
RNA
17%
Carcinogenesis
17%
Agonist
16%
Gene Expression
15%
Enzyme
15%
Structure Activity Relation
15%
Kinase
15%
Phosphotransferase
15%
Tumor Suppressor Protein
14%
Epigenomics
13%
Histone H3
12%
Crystal Structure
12%
Wild Type
11%
Acetylation
11%
Proteasome
11%
G Protein Coupled Receptor
11%
Histone Methyltransferase
11%
Epidermal Growth Factor Receptor
11%
T Cell
11%
Binding Protein
11%
EZH1
10%
Myeloid
10%
SARS Coronavirus
10%
Transcription Factors
9%
Cell Growth
9%
Receptor Tyrosine Kinase
9%
Binding Site
9%
Protein Complexes
9%
Epigenetics
9%
Cereblon
9%
Anticancer
8%
RNA Splicing
8%
SET Domain
8%
BMI1 Protein
8%
Tudor Domain
8%
Keyphrases
Proteolysis Targeting chimera (PROTAC)
78%
Degrader
62%
Enhancer of Zeste Homolog 2 (EZH2)
62%
Structure-activity Relationship
34%
Small Molecules
32%
PRMT1
28%
Polycomb Repressive Complex 2 (PRC2)
28%
Small Molecule Inhibitors
25%
Multiple Myeloma
24%
First-in-class
23%
Chemical Probes
23%
Selective Inhibitor
23%
Methyltransferase
23%
Lysine Methyltransferase
22%
Methylation
22%
Cancer Cells
22%
In Cancer
21%
Structure-activity Relationship Studies
21%
H3K27me3
20%
Epigenetics
18%
Chromatin
18%
Protein Lysine Methyltransferase
18%
Protein Methyltransferase
16%
Urotensin II Receptor Antagonist
16%
SETD8
16%
G Protein-coupled Receptor
15%
Lysine
15%
Arrestin
15%
Chemical Tools
13%
Histone Methyltransferase
13%
Potent Inhibitor
13%
EZH1
13%
Targeted Degradation
13%
Allosteric Inhibitor
13%
Acetylcholine Receptor Antagonists
13%
COVID-19
13%
E3 Ligase
13%
Subtype Selectivity
12%
High-throughput Screening
12%
Acute Myeloid Leukemia
12%
Methyltransferase Inhibitor
12%
Receptor Antagonist
12%
Triple-negative Breast Cancer
12%
EP3 Receptor
12%
Activity Optimization
12%
Targeted Protein Degradation
11%
Human Disease
11%
Co-crystal Structure
11%
Receptor Agonist
11%
Bioavailable
11%
Pharmacology, Toxicology and Pharmaceutical Science
Structure Activity Relationship
57%
Malignant Neoplasm
43%
Lysine
40%
Methyltransferase
39%
Mouse
33%
Receptor
27%
Disease
25%
Multiple Myeloma
21%
G Protein Coupled Receptor
21%
Protein Arginine Methyltransferase
21%
Protein P53
20%
Neoplasm
20%
Transcription Factor EZH2
16%
Tumor Suppressor Protein
16%
Urotensin Receptor Antagonist
16%
Polycomb Repressive Complex 2
13%
High-Throughput Screening
13%
Muscarinic Acetylcholine Receptor Antagonist
13%
Retina S Antigen
12%
Pharmacokinetics
12%
Receptor Agonist
12%
Receptor Antagonist
12%
Cancer Growth
11%
Breast Cancer
11%
Histone
10%
Ligase
10%
Proteasome
9%
Side Effect
9%
Binding Site
9%
Functional Selectivity
9%
Carcinogenesis
8%
Guanine Nucleotide Binding Protein
8%
Partial Agonist
8%
Oxazolidinedione Derivative
8%
SARS Coronavirus
8%
Liver Cell Carcinoma
8%
Beta Glucuronidase
8%
Designer Drug
8%
Opiate
8%
Dopamine Receptor D2
8%
Opiate Receptor
8%
Myeloma
7%
Leukemia
7%
Phosphotransferase
7%
Clozapine N Oxide
6%
Positive Allosteric Modulator
6%
Acute Myeloid Leukemia
6%
Methyltransferase Inhibitor
6%
Histone H3
6%
Adenosine
6%
