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ASSISTANT PROFESSOR | Neuroscience, ASSISTANT PROFESSOR | Neurosurgery, ASSISTANT PROFESSOR | Neurology
Biography
Dr. Saez’s research focuses on the study of the neural basis of human cognition, particularly decision-making, through the examination of invasive brain activity in neurosurgical patients. He combines human electrophysiological and electrochemical recordings during decision-making tasks with computational models of reward and choice. This experimental combination provides access to fast, highly detailed, high signal-to-noise, multi-areal neural activity from the human brain, which is highly suited to studying the relationship of distributed neural activity to aspects of cognition and the use of neurostimulation techniques to modulate behavior and treat cognitive aspects of disease. Dr. Saez completed his postdoctoral training in the laboratories of Drs. Read Montague (Virginia Tech), Robert T. Knight and Ming Hsu (UC Berkeley), where he trained in invasive recordings (DBS, ECoG, sEEG), behavior and computational (RL) models of reward. Prior to that, he obtained his PhD in Neuroscience in Michael Friedlander’s lab (Baylor College of Medicine), where he carried out in vitro electrophysiological recordings in animal models. Before joining Sinai, Dr. Saez held a faculty position at the University of California, Davis.
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Invasive decoding and stimulation of altered reward computations in depression
Saez, I. I. & Saez, I.
NATIONAL INSTITUTE OF MENTAL HEALTH
1/09/21 → 30/06/23
Project: Research
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Electrocorticography of human prefrontal cortex during value-based decision-making
NATIONAL INSTITUTE OF MENTAL HEALTH
1/08/16 → 31/07/21
Project: Research
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Invasive Computational Psychiatry
Saez, I. & Gu, X., 2023, (Accepted/In press) In: Biological Psychiatry.Research output: Contribution to journal › Review article › peer-review
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Subthalamic nucleus deep brain stimulation programming settings do not correlate with Parkinson’s disease severity
Far, R., Saez, I., Sardo, A., Ovruchesky, E., Sperry, L., Zhang, L., Shahlaie, K. & Girgis, F., Sep 2022, In: Acta Neurochirurgica. 164, 9, p. 2271-2278 8 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Gender bias in academia: A lifetime problem that needs solutions
Llorens, A., Tzovara, A., Bellier, L., Bhaya-Grossman, I., Bidet-Caulet, A., Chang, W. K., Cross, Z. R., Dominguez-Faus, R., Flinker, A., Fonken, Y., Gorenstein, M. A., Holdgraf, C., Hoy, C. W., Ivanova, M. V., Jimenez, R. T., Jun, S., Kam, J. W. Y., Kidd, C., Marcelle, E., Marciano, D., & 25 others , 7 Jul 2021, In: Neuron. 109, 13, p. 2047-2074 28 p.Research output: Contribution to journal › Review article › peer-review
Open Access30 Scopus citations -
The impact of sub specialization within functional neurosurgery on patient outcomes in a comprehensive epilepsy center
Clark, A. JS., Samuel, R., Saez, I., Kennedy, J., Seyal, M., Shahlaie, K. & Girgis, F., Jun 2021, In: Clinical Neurology and Neurosurgery. 205, 106636.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Comparison of Intraoperative Computed Tomography Scan with Postoperative Magnetic Resonance Imaging for Determining Deep Brain Stimulation Electrode Coordinates
Girgis, F., Zarabi, H., Said, M., Zhang, L., Shahlaie, K. & Saez, I., Jun 2020, In: World Neurosurgery. 138, p. e330-e335Research output: Contribution to journal › Article › peer-review
4 Scopus citations
Press/Media
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UC Davis Neurological Surgery faculty member awarded for research on decision-making
10/03/21
2 items of Media coverage
Press/Media
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Regret is a gambler’s curse, neuroscientists say
13/09/18 → 17/09/18
2 items of Media coverage
Press/Media
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