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Ian Maze

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Ian Maze

PhD

 https://orcid.org/0000-0003-1490-7781
20062026

Research activity per year

Personal profile

Headline

PROFESSOR | Pharmacological Sciences, PROFESSOR | Neuroscience

Biography

Ian S. Maze, Ph.D., is a neurobiologist with extensive training in the molecular biology and chromatin biochemistry of histone regulation in the mammalian central nervous system. His multidisciplinary and integrative research involves the use of biochemical, biophysical, physiological and behavioral analyses to explore the molecular underpinnings of neurodevelopmental and adult cognitive and psychiatric disorders. Dr. Maze is actively investigating the brains of rodents and postmortem humans, as well as human iPSC-derived neurons, to uncover chromatin-based mechanisms of neurological disease. Multi-Disciplinary Training Areas Biophysics and Systems Pharmacology [BSP], Developmental and Stem Cell Biology [DSCB], Neuroscience [NEU] Education BS, The Ohio State University PhD, Mount Sinai School of Medicine Postdoctoral Fellowship, The Rockefeller University

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  • Dopamine drives persistent remodelling of the maternal brain

    O’Chan, J. C., Di Salvo, G., Cunningham, A. M., Dutta, S., Brindley, E., Weekley, B. H., Chen, W., Iyer, R. R., Wan, E., Zhang, C., Mechawar, N., Turecki, G. & Maze, I., 11 Jun 2026, In: Nature. 654, 8118, p. 465-475 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    1 Scopus citations

  • Reimagining biogenic amine signaling in the brain and beyond

    Vinson, D. A. & Maze, I., Jan 2026, In: Trends in Neurosciences. 49, 1, p. 35-48 14 p.

    Research output: Contribution to journal › Review article › peer-review

    Open Access

  • Transcriptional regulation of ventral hippocampus-nucleus accumbens circuit excitability drives cocaine seeking

    Eagle, A. L., Sugimoto, C., Doyle, M. A., Anderson, D., Mousavi, S. L., Dykstra, M. M., Kuhn, H. M., Murray, B. R., Bastle, R. M., Simmons, S., He, J., Maze, I., Mazei-Robison, M. S. & Robison, A. J., 4 Mar 2026, In: Science advances. 12, 10, eadv1236.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • A Novel Role for the Histone Demethylase JMJD3 in Mediating Heroin-Induced Relapse-Like Behaviors

    Mitra, S., Werner, C. T., Shwani, T., Lopez, A. G., Federico, D., Higdon, K., Li, X., Gobira, P. H., Thomas, S. A., Martin, J. A., An, C., Chandra, R., Maze, I., Neve, R., Lobo, M. K., Gancarz, A. M. & Dietz, D. M., 15 Mar 2025, In: Biological Psychiatry. 97, 6, p. 602-613 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    4 Scopus citations

  • Bidirectional histone monoaminylation dynamics regulate neural rhythmicity

    Zheng, Q., Weekley, B. H., Vinson, D. A., Zhao, S., Bastle, R. M., Thompson, R. E., Stransky, S., Ramakrishnan, A., Cunningham, A. M., Dutta, S., Chan, J. C., Di Salvo, G., Chen, M., Zhang, N., Wu, J., Fulton, S. L., Kong, L., Wang, H., Zhang, B. & Vostal, L. & 9 others, Upad, A., Dierdorff, L., Shen, L., Molina, H., Sidoli, S., Muir, T. W., Li, H., David, Y. & Maze, I., 23 Jan 2025, In: Nature. 637, 8047, p. 974-982 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    42 Scopus citations
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