Research output per year
Research output per year
Personal profile
Headline
PROFESSOR | Pharmacological Sciences, PROFESSOR | Neuroscience
Biography
Ian S. Maze, Ph.D., is a neurobiologist with extensive training in the molecular biology and chromatin biochemistry of histone regulation in the mammalian central nervous system. His multidisciplinary and integrative research involves the use of biochemical, biophysical, physiological and behavioral analyses to explore the molecular underpinnings of neurodevelopmental and adult cognitive and psychiatric disorders. Dr. Maze is actively investigating the brains of rodents and postmortem humans, as well as human iPSC-derived neurons, to uncover chromatin-based mechanisms of neurological disease. Multi-Disciplinary Training Areas Biophysics and Systems Pharmacology [BSP], Developmental and Stem Cell Biology [DSCB], Neuroscience [NEU] Education BS, The Ohio State University PhD, Mount Sinai School of Medicine Postdoctoral Fellowship, The Rockefeller University
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Collaborations and top research areas from the last five years
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Histone H3 dopaminylation in nucleus accumbens, but not medial prefrontal cortex, contributes to cocaine-seeking following prolonged abstinence
Stewart, A. F., Lepack, A. L., Fulton, S. L., Safovich, P. & Maze, I., Jun 2023, In: Molecular and Cellular Neurosciences. 125, 103824.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Induction of astrocytic Slc22a3 regulates sensory processing through histone serotonylation
Sardar, D., Cheng, Y. T., Woo, J., Choi, D. J., Lee, Z. F., Kwon, W., Chen, H. C., Lozzi, B., Cervantes, A., Rajendran, K., Huang, T. W., Jain, A., Arenkiel, B. R., Maze, I. & Deneen, B., 16 Jun 2023, In: Science. 380, 6650, eade0027.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Post-translational modifications of histone proteins by monoamine neurotransmitters
Al-Kachak, A. & Maze, I., Jun 2023, In: Current Opinion in Chemical Biology. 74, 102302.Research output: Contribution to journal › Review article › peer-review
Open Access4 Scopus citations -
Chromatin profiling in human neurons reveals aberrant roles for histone acetylation and BET family proteins in schizophrenia
Farrelly, L. A., Zheng, S., Schrode, N., Topol, A., Bhanu, N. V., Bastle, R. M., Ramakrishnan, A., Chan, J. C., Cetin, B., Flaherty, E., Shen, L., Gleason, K., Tamminga, C. A., Garcia, B. A., Li, H., Brennand, K. J. & Maze, I., Dec 2022, In: Nature Communications. 13, 1, 2195.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Histone H3 dopaminylation in ventral tegmental area underlies heroin-induced transcriptional and behavioral plasticity in male rats
Fulton, S. L., Mitra, S., Lepack, A. E., Martin, J. A., Stewart, A. F., Converse, J., Hochstetler, M., Dietz, D. M. & Maze, I., Sep 2022, In: Neuropsychopharmacology. 47, 10, p. 1776-1783 8 p.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations
Press/Media
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2023 Blavatnik National Awards for Young Scientists announced
26/07/23
2 items of Media coverage
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New York Academy of Sciences: 2023 Blavatnik National Awards for Young Scientists Announced
26/07/23
1 item of Media coverage
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Baylor College of Medicine: Astrocyte Processing of Serotonin Regulates Olfactory Perception
16/06/23
1 item of Media coverage
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Baylor College of Medicine: Astrocyte processing of serotonin regulates olfactory perception
15/06/23
1 item of Media coverage
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Astrocyte processing of serotonin regulates olfactory perception
15/06/23
3 items of Media coverage
Press/Media