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INSTRUCTOR | AI and Human Health, INSTRUCTOR | Neurology
Biography
Francesco La Rosa, PhD, is an Instructor in the Departments of Neurology and Artificial Intelligence and Human Health at the Icahn School of Medicine at Mount Sinai. His research at Mount Sinai focuses on developing advanced machine learning and MRI analysis methods to study biomarkers of aging and neurological conditions. Dr. La Rosa uses imaging data, statistical modeling, and AI-driven approaches to identify robust biomarkers that support diagnosis, prognosis, and monitoring of treatment responses in neurological diseases.
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Collaborations and top research areas from the last five years
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MRI signature of brain age underlying post-traumatic stress disorder in World Trade Center responders
Invernizzi, A., La Rosa, F., Sather, A., Rechtman, E., Nabeel, I., Morrison, R. S., Pellecchia, A. C., Santiago-Michels, S., Bromet, E. J., Lucchini, R. G., Luft, B. J., Clouston, S. A., Beck, E. S., Tang, C. Y. & Horton, M. K., Dec 2026, In: Translational Psychiatry. 16, 1, 23.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
A Novel Convolutional Neural Network for Automated Multiple Sclerosis Brain Lesion Segmentation
Dereskewicz, E., La Rosa, F., Dos Santos Silva, J., Sizer, E., Kohli, A., Wynen, M., Mullins, W. A., Maggi, P., Levy, S., Onyemeh, K., Ayci, B., Solomon, A. J., Assländer, J., Al-Louzi, O., Reich, D. S., Sumowski, J. & Beck, E. S., 1 Sep 2025, In: Journal of Neuroimaging. 35, 5, e70085.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
BrainAgeNeXt: Advancing brain age modeling for individuals with multiple sclerosis
La Rosa, F., Dos Santos Silva, J., Dereskewicz, E., Invernizzi, A., Cahan, N., Galasso, J., Garcia, N., Graney, R., Levy, S., Verma, G., Balchandani, P., Reich, D. S., Horton, M., Greenspan, H., Sumowski, J., Bach Cuadra, M. & Beck, E. S., 25 Feb 2025, In: Imaging Neuroscience. 3, imag_a_00487.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Fluid and White Matter Suppression contrasts MRI improves Deep Learning detection of Multiple Sclerosis Cortical Lesions
Gordaliza, P. M., Müller, J., Cagol, A., Molchanova, N., La Rosa, F., Tsagkas, C., Granziera, C. & Cuadra, M. B., Jan 2025, In: NeuroImage: Clinical. 48, 103818.Research output: Contribution to journal › Article › peer-review
Open Access -
Lesion-Based Disconnectome Explains Cognitive Outcomes in Multiple Sclerosis
dos Santos Silva, J., Vasconcelos, C. C. F., Spedo, C. T., Azevedo, C. A., Lopes, L. C. S., La Rosa, F., Moura, C. B., Nascimento, O. & Lopes, F. C. R., 1 Sep 2025, In: Journal of Neuroimaging. 35, 5, e70081.Research output: Contribution to journal › Article › peer-review
Open Access
Press/Media
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World Trade Center responders with PTSD show signs of accelerated brain aging
Beck, E., Nabeel, I., Horton, M., Morrison, R. S., La Rosa, F. & Rechtman, E.
6/02/26
1 item of Media coverage
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Reports Outline Traumatic Stress Disorders Findings from Icahn School of Medicine at Mount Sinai (MRI signature of brain age underlying post-traumatic stress disorder in World Trade Center responders)
Beck, E., Nabeel, I., Morrison, R. S., La Rosa, F. & Rechtman, E.
17/12/25
1 item of Media coverage
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Researchers at Icahn School of Medicine at Mount Sinai Have Reported New Data on Multiple Sclerosis (BrainAgeNeXt: Advancing brain age modeling for individuals with multiple sclerosis)
Verma, G., Horton, M., Sumowski, J., Balchandani, P. & La Rosa, F.
27/08/25
1 item of Media coverage
Press/Media