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Ernesto Guccione

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Ernesto Guccione

PhD

20012026

Research activity per year

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ASSOCIATE PROFESSOR | Oncological Sciences ASSOCIATE PROFESSOR | Pharmacological Sciences

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  • A synergistic interaction between PRMT5 and LSD1 inhibitors in AML

    Param, N. J., Arceci, E., Fiorentino, F., Pignata, L., Torre, D., Gutiérrez-Trejo, N., Fong, J. Y., Goy, P. A., Han, B. Y., Lambona, C., Bello, E. D., Castiello, C., Barone, M., Schwarz, M., Arrowsmith, C., Ito, K., Scherle, P., Wee, D. K. B., Ndoye, S. & Tabaglio, T. & 9 others, Jeyasekharan, A. D., Lakshmanan, M., Cirilli, R., Habisch, H., Madl, T., Mattevi, A., Valente, S., Mai, A. & Guccione, E., 27 Mar 2026, In: Science advances. 12, 13, eaea4059.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • Effective therapeutic targeting of CTNNB1-mutant hepatoblastoma with WNTinib

    Balaseviciute, U., Huguet-Pradell, J., Abril-Fornaguera, J., Gris-Oliver, A., Rialdi, A., Fernández-Martínez, E., Montironi, C., Del Pozo, V., Houghton, P., Zanatto, L., Mesropian, A., Keraite, I., Thung, S., Armengol, C., Sancho-Bru, P., Guccione, E., Pinyol, R. & Llovet, J. M., Apr 2026, In: Molecular Oncology. 20, 4, p. 920-932 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • Transposable element–gene chimera cartography, origination and role in enhancing transcriptome plasticity

    Cheon, Y., Alvstad, E. G., Torre, D., Quach, D. T., Nguyen, J., Hyun, K., Zhou, M., Yu, T., Liu, L., Yoon, Y., Reese, F., Faraone, L., Li, Y., Arnold, F. J., Fstkchyan, Y. S., Basu, U., Kvon, E., Valente, E. M., Ho, J. S. Y. & Byun, M. & 5 others, Guccione, E., Shi, Y., Weng, Z., Seldin, M. & Marazzi, I., Mar 2026, In: Nature Structural and Molecular Biology. 33, 3, p. 448-463 16 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • Developing splice-switching oligonucleotides for urea cycle disorder using an integrated diagnostic and therapeutic platform

    Ow, J. R., Imagawa, E., Chen, F., Cher, W. Y., Chan, S. Y. T., Gurrampati, R. R., Ramadass, V., Loke, M. F., Tabaglio, T., Nishida, H., Tsunogai, T., Yazaki, M., Ch'ng, G. S., Lakshmanan, M., Lee, S. S., Ying, J. Y., Guccione, E., Oishi, K. & Wee, K. B., Aug 2025, In: Journal of Hepatology. 83, 2, p. 411-425 15 p.

    Research output: Contribution to journal › Article › peer-review

    3 Scopus citations

  • Differential splice isoforms of mouse CDK2 play functionally redundant roles during mitotic and meiotic division

    Palmer, N., Kalem-Yapar, N. E., Hulteń, H., Keles, U., Talib, S. Z. A., Ow, J. R., Tabaglio, T., Goh, C. M. F., Zhao, L. N., Guccione, E., Liu, K. & Kaldis, P., Oct 2025, In: Journal of Cell Science. 138, 19, jcs264291.

    Research output: Contribution to journal › Article › peer-review

    Open Access
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