Research output per year
Research output per year
Personal profile
Headline
DEAN FOR ACADEMIC AND SCIENTIFIC AFFAIRS DIRECTOR FRIEDMAN BRAIN INSTITUTE PROFESSOR | Neuroscience PROFESSOR | PharmacologicalSciences PROFESSOR | Psychiatry
Biography
Biography Dr. Nestler is the Nash Family Professor of Neuroscience and Director of the Friedman Brain Institute. His laboratory studies the molecular mechanisms of drug addiction and depression in animal models. Visit Eric Nestler's http://neuroscience.mssm.edu/nestler/ Laboratory of Molecular Psychiatry, http://neuroscience.mssm.edu/nestler/contecenter/index.html Conte Center on Depressionand http://transmitter.neuro.mssm.edu/nestler/nidappg/index.html NIDA Program Project Grant for more information.
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Collaborations and top research areas from the last five years
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Astrocyte fatty acid metabolism as a driver of risk for major depressive disorder
Fitzgerald, E., O’Toole, N., Pokhvisneva, I., Nestler, E. J., Turecki, G., Nagy, C. & Meaney, M. J., Dec 2026, In: Nature Communications. 17, 1, 4985.Research output: Contribution to journal › Article › peer-review
Open Access -
Cellular and molecular mechanisms of astrocyte plasticity in learning and memory
Holt, L. M., Nestler, E. J. & Olsen, M. L., May 2026, In: Trends in Neurosciences. 49, 5, p. 344-357 14 p.Research output: Contribution to journal › Review article › peer-review
Open Access -
CUT&RUN as a Powerful Tool for Chromatin Profiling: A Focus on Neuropsychiatric Disorders
Holt, L. M., Chen, E. P., Hughes, B. W. & Nestler, E. J., 15 Aug 2026, In: Biological Psychiatry. 100, 4, p. 369-376 8 p.Research output: Contribution to journal › Review article › peer-review
Open Access -
Discovery of small molecules and a druggable groove that regulate DNA binding and release of the AP-1 transcription factor ΔFOSB
McNeme, S., Yim, Y. Y., Kumar, A., Li, Y., Hughes, B., St Romain, C. P., Aglyamova, G., Chen, J., Nguyen, N. D., Fan, S., Stephens, G. S., Zhao, W. N., Kruzshak, S., Estill, M., Brener, C., Tofani, S., Kumar, A., Chen, E. P., Takatka, N. & Robison, A. J. & 9 others, , Feb 2026, In: Journal of Biological Chemistry. 302, 2, 111080.Research output: Contribution to journal › Article › peer-review
Open Access -
Efficient In Vivo Pharmacological Inhibition of ΔFOSB, an AP-1 Transcription Factor, in the Brain
McNeme, S., Kumar, A., Yim, Y. Y., Hughes, B. W., St Romain, C., Li, Y., Kumar, A., Bao, Q., Estill, M., Fan, S., Takatka, N., Chen, E. P., Rivera, M., Chen, H., Robison, A. J., Machius, M., Haggarty, S. J., Chin, J., Nestler, E. J. & Zhou, J. & 1 others, , 1 Apr 2026, In: ACS Chemical Neuroscience. 17, 7, p. 1316-1331 16 p.Research output: Contribution to journal › Article › peer-review
Open Access
Press/Media
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The baffling science of SSRIs: how do they really work?
Horowitz, M., Nestler, E. J. & Jha, M.
27/08/26
1 item of Media coverage
Press/Media
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Mount Sinai’s $1m XPRIZE bet: reset immune system, slow aging
Merad, M., Nestler, E. J., Walker, R., Marron, T., Carr, B., Fayad, Z. & Elahi, F.
26/08/26
1 item of Media coverage
Press/Media
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The Pershing Square Foundation’s 2027 MIND (Maximizing Innovation in Neuroscience Discovery) Prize Opens for Applications
17/08/26 → 18/08/26
17 items of Media coverage
Press/Media
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Mount Sinai Advances As Milestone 2 Awardee In XPRIZE Healthspan, A $101 Million Global Competition Focused On Extending Healthy Aging
Merad, M., Nestler, E. J., Walker, R., Marron, T., Carr, B., Fayad, Z. & Elahi, F.
11/08/26 → 12/08/26
8 items of Media coverage
Press/Media
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Mount Sinai Reaches Milestone 2 in $101 Million XPRIZE Healthspan Competition
Merad, M., Nestler, E. J., Walker, R., Marron, T., Carr, B., Fayad, Z. & Elahi, F.
12/08/26
2 items of Media coverage
Press/Media