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Identification of human cytomegalovirus life cycle stage-specific therapeutics
Tortorella, D. D. & Tortorella, D.
National Institute of Allergy and Infectious Diseases
22/07/19 → 30/06/23
Project: Research
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Training Program in Mechanisms of Virus-Host Interactions
Tortorella, D. D., Palese, P. & Tortorella, D.
National Institute of Allergy and Infectious Diseases
1/08/00 → 31/07/23
Project: Research
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Anti-drug Conjugates That Target Human Cytomegalovirus Infected Cells
National Institute of Allergy and Infectious Diseases
8/12/17 → 30/11/20
Project: Research
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Development of biologics targeting human cytomegalovirus envelope proteins
National Institute of Allergy and Infectious Diseases
26/06/17 → 31/05/19
Project: Research
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Investigating N-arylpyrimidinamine (NAPA) compounds as early-stage inhibitors against human cytomegalovirus
Parsons, A. J., Ophir, S. I., Gardner, T. J., Paredes, J. C., Stein, K. R., Kwasny, S. M., Cardinale, S. C., Torhan, M., Prichard, M. N., James, S. H., Atanasoff, K. E., G-Dayanandan, N., Bowlin, T. L., Opperman, T. J. & Tortorella, D., Jan 2023, In: Antiviral Research. 209, 105474.Research output: Contribution to journal › Article › peer-review
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Development of broadly neutralizing antibodies targeting the cytomegalovirus subdominant antigen gH
Parsons, A. J., Ophir, S. I., Duty, J. A., Kraus, T. A., Stein, K. R., Moran, T. M. & Tortorella, D., Dec 2022, In: Communications Biology. 5, 1, 387.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Immunoglobulin A antibody composition is sculpted to bind the self gut microbiome
Yang, C., Chen-Liaw, A., Spindler, M. P., Tortorella, D., Moran, T. M., Cerutti, A. & Faith, J. J., Jul 2022, In: Science immunology. 7, 73, eabg3208.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
An influenza virus hemagglutinin-based vaccine platform enables the generation of epitope specific human cytomegalovirus antibodies
Behzadi, M. A., Stein, K. R., Bermúdez-González, M. C., Simon, V., Nachbagauer, R. & Tortorella, D., Jun 2019, In: Vaccines. 7, 2, 51.Research output: Contribution to journal › Article › peer-review
Open Access -
CD46 facilitates entry and dissemination of human cytomegalovirus
Stein, K. R., Gardner, T. J., Hernandez, R. E., Kraus, T. A., Duty, J. A., Ubarretxena-Belandia, I., Moran, T. M. & Tortorella, D., 1 Dec 2019, In: Nature Communications. 10, 1, 2699.Research output: Contribution to journal › Article › peer-review
Open Access33 Scopus citations
Press / Media
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Sorrento Therapeutics Announces Covishield (Sti-9167), a Broad-Spectrum Neutralizing Antibody, Potently Neutralizes Omicron and Omicron (+R346k) Variants of Sars-Cov-2
James Duty, & Domenico Tortorella
21/01/22 → 24/01/22
18 items of Media coverage
Press/Media
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Sorrento Therapeutics Announces Covishield (Sti-9167), A Broad-Spectrum Neutralizing Antibody, Potently Neutralizes Omicron And Omicron (+R346k) Variants Of Sars-Cov-2
James Duty, & Domenico Tortorella
21/01/22
1 item of Media coverage
Press/Media
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SORRENTO THERAPEUTICS ANNOUNCES COVISHIELD (STI-9167), A BROAD-SPECTRUM NEUTRALIZING ANTIBODY, POTENTLY NEUTRALIZES OMICRON AND OMICRON (+R346K) VARIANTS OF SARS-COV-2; - COVISHIELD (STI-9167) neutralizing antibody (nAb) was discovered by scientists from
James Duty, & Domenico Tortorella
20/01/22
59 items of Media coverage
Press/Media
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Digital health startups shattered fundraising records last year, backed by bullish venture capital
20/01/22
1 item of Media coverage
Press/Media
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US Patent Issued to ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI on Nov. 30 for "Broadly neutralizing anti-human cytomegalovirus (HCMV) antibodies and methods of use thereof" (New York Inventors)
Thomas Gardner, Thomas Moran & Domenico Tortorella
1/12/21
1 item of Media coverage
Press/Media