Dr. Zamarin is a physician-scientist with a research interest in immunology of gynecologic cancers. The overarching goals of his clinical and laboratory research programs are to establish the mechanisms underpinning the resistance of gynecologic cancers to immune response and immunotherapy and to develop novel therapeutic approaches addressing these mechanisms. Dr. Zamarin has served as a principal investigator and a translational chair on multiple institutional and cooperative group clinical trials exploring novel immunotherapy combinations in gynecologic cancers and other solid tumors. His laboratory uses mouse models to explore the mechanisms of tumor-immune system interactions and to develop novel therapeutics, with particular focus on oncolytic viruses, vaccines, and targeted therapies.

Dr. Zamarin obtained his MD and PhD degrees from the Mount Sinai School of Medicine. He completed residency in Internal Medicine at the Mount Sinai Hospital and fellowship in Hematology/Oncology at the Memorial Sloan Kettering Cancer Center, where his research was focused on the mechanisms of response and resistance to cancer immunotherapy and development of novel immunotherapy treatment approaches. He has spent a decade as a faculty and Translational Research Director in Gynecologic Medical Oncology at the Memorial Sloan Kettering Cancer Center before transitioning to his current role in September of 2023.

ASSOCIATE PROFESSOR | Tisch Cancer Institute