Research output per year
Research output per year
Personal profile
Headline
Associate Computational Scientist
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Dive into the research topics where Darwin D'Souza is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Research output
- 8 Article
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Intratumoral dendritic cell–CD4+ T helper cell niches enable CD8+ T cell differentiation following PD-1 blockade in hepatocellular carcinoma
Magen, A., Hamon, P., Fiaschi, N., Soong, B. Y., Park, M. D., Mattiuz, R., Humblin, E., Troncoso, L., D’souza, D., Dawson, T., Kim, J., Hamel, S., Buckup, M., Chang, C., Tabachnikova, A., Schwartz, H., Malissen, N., Lavin, Y., Soares-Schanoski, A. & Giotti, B. & 33 others, , Jun 2023, In: Nature Medicine. 29, 6, p. 1389-1399 11 p.Research output: Contribution to journal › Article › peer-review
Open Access77 Scopus citations -
Monocytes re-enter the bone marrow during fasting and alter the host response to infection
Janssen, H., Kahles, F., Liu, D., Downey, J., Koekkoek, L. L., Roudko, V., D'Souza, D., McAlpine, C. S., Halle, L., Poller, W. C., Chan, C. T., He, S., Mindur, J. E., Kiss, M. G., Singh, S., Anzai, A., Iwamoto, Y., Kohler, R. H., Chetal, K. & Sadreyev, R. I. & 5 others, , 11 Apr 2023, In: Immunity. 56, 4, p. 783-796.e7Research output: Contribution to journal › Article › peer-review
Open Access50 Scopus citations -
TREM2 macrophages drive NK cell paucity and dysfunction in lung cancer
Park, M. D., Reyes-Torres, I., LeBerichel, J., Hamon, P., LaMarche, N. M., Hegde, S., Belabed, M., Troncoso, L., Grout, J. A., Magen, A., Humblin, E., Nair, A., Molgora, M., Hou, J., Newman, J. H., Farkas, A. M., Leader, A. M., Dawson, T., D’Souza, D. & Hamel, S. & 13 others, , May 2023, In: Nature Immunology. 24, 5, p. 792-801 10 p.Research output: Contribution to journal › Article › peer-review
44 Scopus citations -
A shift in lung macrophage composition is associated with COVID-19 severity and recovery
Chen, S. T., Park, M. D., Del Valle, D. M., Buckup, M., Tabachnikova, A., Thompson, R. C., Simons, N. W., Mouskas, K., Lee, B., Geanon, D., D'Souza, D., Dawson, T., Marvin, R., Nie, K., Zhao, Z., LeBerichel, J., Chang, C., Jamal, H., Akturk, G. & Chaddha, U. & 16 others, , 14 Sep 2022, In: Science Translational Medicine. 14, 662, abn5168.Research output: Contribution to journal › Article › peer-review
Open Access34 Scopus citations -
Comprehensive Characterization of the Check for updates Multiple Myeloma Immune Microenvironment Using Integrated scRNA-seq, CyTOF, and CITE-seq Analysis
Yao, L., Jayasinghe, R. G., Lee, B. H., Bhasin, S. S., Pilcher, W., Doxie, D. B., Gonzalez-Kozlova, E., Dasari, S., Fiala, M. A., Pita-Juarez, Y., Strausbauch, M., Kelly, G., Thomas, B. E., Kumar, S. K., Cho, H. J., Anderson, E., Wendl, M. C., Dawson, T., D’souza, D. & Oh, S. T. & 17 others, , 2022, In: Cancer research communications. 2, 10, p. 1255-1265 11 p.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations
Press/Media
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Icahn School of Medicine at Mount Sinai Researcher Adds New Findings in the Area of Cancer (Hematopoietic aging promotes cancer by fueling IL-1 -driven emergency myelopoiesis)
Hegde, S., Merad, M., Nie, K., Kim-Schulze, S., D'Souza, D., Hamon, P., Dawson, T., Brown, B., Vabret, N., Swirski, F. & Chen, Z.
19/09/24
1 item of Media coverage
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Investigators at Icahn School of Medicine at Mount Sinai Discuss Findings in Liver Cancer [Intratumoral Dendritic Cell-cd4(+) T Helper Cell Niches Enable Cd8(+) T Cell Differentiation Following Pd-1 Blockade In Hepatocellular Carcinoma]
Hegde, S., Lavin, Y., Merad, M., Kim-Schulze, S., D'Souza, D., Hamon, P., Dawson, T., Tsankov, A., Rahman, A., Schwartz, M., Gnjatic, S., Ward, S., Kamphorst, A. O. & Giotti, B.
29/08/23
1 item of Media coverage
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Researchers from Icahn School of Medicine at Mount Sinai Detail Findings in Lung Cancer (Trem2 Macrophages Drive Nk Cell Paucity and Dysfunction In Lung Cancer)
Hegde, S., Merad, M., D'Souza, D., Dawson, T., Ferrari de Andrade, L., Brown, B., Horowitz, A., Kamphorst, A. O., Bhardwaj, N., Hamon, P. & Newman, J.
5/07/23
1 item of Media coverage
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Mount Sinai Hospital: Study Reveals a Trio of Immune Cells Vital in Response to Liver Cancer Immunotherapy
Hegde, S., Merad, M., Kim-Schulze, S., D'Souza, D., Dawson, T., Rahman, A., Schwartz, M., Marron, T., Gnjatic, S., Kamphorst, A. O., Lavin, Y., Ward, S., Hamon, P. & Giotti, B.
16/06/23
1 item of Media coverage
Press/Media
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Study Reveals a Trio of Immune Cells Vital in Response to Liver Cancer Immunotherapy
Hegde, S., Merad, M., Kim-Schulze, S., D'Souza, D., Dawson, T., Rahman, A., Schwartz, M., Marron, T., Gnjatic, S., Kamphorst, A. O., Lavin, Y., Ward, S., Hamon, P. & Giotti, B.
15/06/23
3 items of Media coverage
Press/Media