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1997 …2023

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ASSISTANT PROFESSOR | Psychiatry

Biography

Biography Dr. Pinto’s laboratory focuses on identifying genes and biological pathways involved in various neurodevelopmental disorders, including autism, intellectual disability, epilepsy, and rett syndrome-like phenotypes. Dr. Pinto integrates various forms of genetic variation (deletions, duplications, indels, single-point mutations), with gene expression, epigenetics and clinical data, using a combination of innovative high-throughput experimental and bioinformatics approaches, that altogether could implicate novel risk factors and provide insights into the mechanisms underlying these disorders. Dr. Pinto’s laboratory also works with worldwide clinical collaborators that are responsible for patients and families recruitment and phenotypic examination. Multi-Disciplinary Training Areas Genetics and Genomic Sciences [GGS], Neuroscience [NEU] Education MSc, MSc, University of Porto PhD, University of Utrecht Postdoctoral, Hospital for Sick Children Toronto Research For more information see the https://pintolab.mssm.edu Pinto Lab website.

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  • Schizophrenia-associated somatic copy-number variants from 12,834 cases reveal recurrent NRXN1 and ABCB11 disruptions

    Brain Somatic Mosaicism Network & Psychiatric Genomic Consortium Schizophrenia and CNV workgroup, 9 Aug 2023, In: Cell Genomics. 3, 8, 100356.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    4 Scopus citations
  • Common Genetic Variation and Age of Onset of Anorexia Nervosa

    Watson, H. J., Thornton, L. M., Yilmaz, Z., Baker, J. H., Coleman, J. R. I., Adan, R. A. H., Alfredsson, L., Andreassen, O. A., Ask, H., Berrettini, W. H., Boehnke, M., Boehm, I., Boni, C., Buehren, K., Bulant, J., Burghardt, R., Chang, X., Cichon, S., Cone, R. D., Courtet, P., & 157 othersCrow, S., Crowley, J. J., Danner, U. N., de Zwaan, M., Dedoussis, G., DeSocio, J. E., Dick, D. M., Dikeos, D., Dina, C., Djurovic, S., Dmitrzak-Weglarz, M., Docampo-Martinez, E., Duriez, P., Egberts, K., Ehrlich, S., Eriksson, J. G., Escaramís, G., Esko, T., Estivill, X., Farmer, A., Fernández-Aranda, F., Fichter, M. M., Föcker, M., Foretova, L., Forstner, A. J., Frei, O., Gallinger, S., Giegling, I., Giuranna, J., Gonidakis, F., Gorwood, P., Gratacòs, M., Guillaume, S., Guo, Y., Hakonarson, H., Hauser, J., Havdahl, A., Hebebrand, J., Helder, S. G., Herms, S., Herpertz-Dahlmann, B., Herzog, W., Hinney, A., Hübel, C., Hudson, J. I., Imgart, H., Jamain, S., Janout, V., Jiménez-Murcia, S., Jones, I. R., Julià, A., Kalsi, G., Kaminská, D., Kaprio, J., Karhunen, L., Kas, M. J. H., Keel, P. K., Kennedy, J. L., Keski-Rahkonen, A., Kiezebrink, K., Klareskog, L., Klump, K. L., Knudsen, G. P. S., La Via, M. C., Le Hellard, S., Leboyer, M., Li, D., Lilenfeld, L., Lin, B., Lissowska, J., Luykx, J., Magistretti, P., Maj, M., Marsal, S., Marshall, C. R., Mattingsdal, M., Meulenbelt, I., Micali, N., Mitchell, K. S., Monteleone, A. M., Monteleone, P., Myers, R., Navratilova, M., Ntalla, I., O'Toole, J. K., Ophoff, R. A., Padyukov, L., Pantel, J., Papežová, H., Pinto, D., Raevuori, A., Ramoz, N., Reichborn-Kjennerud, T., Ricca, V., Ripatti, S., Ripke, S., Ritschel, F., Roberts, M., Rotondo, A., Rujescu, D., Rybakowski, F., Scherag, A., Scherer, S. W., Schmidt, U., Scott, L. J., Seitz, J., Silén, Y., Šlachtová, L., Slagboom, P. E., Slof-Op ‘t Landt, M. C. T., Slopien, A., Sorbi, S., Świątkowska, B., Tortorella, A., Tozzi, F., Treasure, J., Tsitsika, A., Tyszkiewicz-Nwafor, M., Tziouvas, K., van Elburg, A. A., van Furth, E. F., Walton, E., Widen, E., Zerwas, S., Zipfel, S., Bergen, A. W., Boden, J. M., Brandt, H., Crawford, S., Halmi, K. A., Horwood, L. J., Johnson, C., Kaplan, A. S., Kaye, W. H., Mitchell, J. E., Olsen, C. M., Pearson, J. F., Pedersen, N. L., Strober, M., Werge, T., Whiteman, D. C., Woodside, D. B., Gordon, S., Maguire, S., Larsen, J. T., Parker, R., Petersen, L. V., Jordan, J., Kennedy, M., Wade, T. D., Birgegård, A., Lichtenstein, P., Landén, M., Martin, N. G., Mortensen, P. B., Breen, G. & Bulik, C. M., Oct 2022, In: Biological Psychiatry Global Open Science. 2, 4, p. 368-378 11 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    7 Scopus citations
  • Correction: High-resolution transcriptomics informs glial pathology in human temporal lobe epilepsy (Acta Neuropathologica Communications, (2022), 10, 1, (149), 10.1186/s40478-022-01453-1)

    Pai, B., Tome‑Garcia, J., Cheng, W. S., Nudelman, G., Beaumont, K. G., Ghatan, S., Panov, F., Caballero, E., Sarpong, K., Marcuse, L., Yoo, J., Jiang, Y., Schaefer, A., Akbarian, S., Sebra, R., Pinto, D., Zaslavsky, E. & Tsankova, N. M., Dec 2022, In: Acta neuropathologica communications. 10, 1, 171.

    Research output: Contribution to journalComment/debate

    Open Access
    1 Scopus citations
  • Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors

    Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Eating Disorders Working Group of the Psychiatric Genomics Consortium, German Borderline Genomics Consortium, MVP Suicide Exemplar Workgroup & VA Million Veteran Program, 1 Feb 2022, In: Biological Psychiatry. 91, 3, p. 313-327 15 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    79 Scopus citations
  • High-resolution transcriptomics informs glial pathology in human temporal lobe epilepsy

    Pai, B., Tome-Garcia, J., Cheng, W. S., Nudelman, G., Beaumont, K. G., Ghatan, S., Panov, F., Caballero, E., Sarpong, K., Marcuse, L., Yoo, J., Jiang, Y., Schaefer, A., Akbarian, S., Sebra, R., Pinto, D., Zaslavsky, E. & Tsankova, N. M., Dec 2022, In: Acta neuropathologica communications. 10, 1, 149.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    13 Scopus citations