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CLINICAL PROFESSOR | Radiology
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Certifications American Board of Radiology Education MD, Howard University Col. of Medicine Residency, Radiology Brigham and Women's Hospital, Harvard Medical School Biography Dr. Claudia Henschke is a Professor of Radiology and heads the Lung and Cardiac Screening Program at the Mount Sinai Medical Center. A pioneer and leading expert in the field of diagnostic radiology, Dr. Henschke has long believed that smokers and former smokers should consider being tested with low-dose CT scans to detect lung cancer when a tumor is still small enough to be cured. Dr. Henschke has more than 20 years of clinical and research experience in this area and , since 1993, has led city, state, national, and international projects that have resulted in the diagnosis of some 800 lung cancers. She and her team have created a protocol that has set an international standard for performing low-dose CT scans and managing findings which require additional testing. Her team has developed techniques that provide 3D growth assessment of a lesion. Using these techniques lesion growth can be measured and compared to the rate of growth seen in malignant tumors. This can help distinguish those lesions that are benign from those that are malignant. Dr. Henschke heads the International Early Lung Cancer Action Program (I-ELCAP) which is an international collaborative group consisting of experts on lung cancer related issues. More than 60 sites in the world have participated in this research program. Dr. Henschke received a M.S. in mathematical statistics from Southern Methodist University and her PhD in mathematical statistics and computer science in 1969 from the University of Georgia. She was awarded her medical degree from Howard University in 1977. She completed her radiology residency at the Peter Bent Brigham Hospital, Harvard Medical School, and in 1981 was named to the faculty of the Department of Radiology at Harvard Medical School. Dr. Henschke was a Professor of Radiology at Weill Cornell Medical College before joining Mount Sinai. Dr. Henschke has authored over 250 peer reviewed publications, two books and more than 30 chapters in books. Clinical Trials http://icahn.mssm.edu/research/clinical-trials/health-topics/heart/09-2019 American Legacy Smoking Cessation Study http://icahn.mssm.edu/research/clinical-trials/09-2017 Pulmonary Diseases from Secondhand Smoke
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A Game-Changing 20 Years: Progress and Future Directions in Lung Cancer Screening
Lam, S., Baldwin, D. R., Devaraj, A., Field, J., Henschke, C. I., Heuvelmans, M. A., Huber, R. M., Jones, C., Borondy-Kitts, A., Ching Li, M. S., Myers, R., Osarogiagbon, R. U., Robbins, H. A., Tammemägi, M. C., Taylor, K. L., Triphuridet, N., Williams, R. M. & Yankelevitz, D., Feb 2026, In: Journal of Thoracic Oncology. 21, 2, p. 235-252 18 p.Research output: Contribution to journal › Review article › peer-review
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AI-CVD-HF: A heart failure risk prediction model based on coronary artery calcium scans compared with PREVENT-HF
Mirjalili, S. R., Atlas, K., Reeves, A. P., Zhang, C., Wasserthal, J., Azimi, A., Hashemi, A., Mozafarybazargany, M., Ghaffari Jolfayi, A., Atlas, T., Henschke, C. I., Yankelevitz, D. F., Zulueta, J. J., Fan, W., Mechanick, J. I., Branch, A. D., Fayad, Z., McConnell, M. V., Rana, J. S. & Vliegenthart, R. & 11 others, , 2026, (Accepted/In press) In: American Journal of Preventive Cardiology. 101464.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
AI-derived left-to-right cardiac chamber volume ratios in coronary artery calcium scans strongly predict heart failure
Naghavi, M., Mirjalili, S. R., Atlas, K., Reeves, A. P., Zhang, C., Wasserthal, J., Azimi, A., Hashemi, A., Mozafarybazargany, M., Atlas, T., Henschke, C. I., Yankelevitz, D. F., Zulueta, J. J., Mechanick, J. I., Branch, A. D., Yip, R., Roy, S. K., Nasir, K., Fayad, Z. & McConnell, M. V. & 12 others, , Apr 2026, In: European Heart Journal Cardiovascular Imaging. 27, 4, p. 791-802 12 p.Research output: Contribution to journal › Article › peer-review
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Artificial Intelligence–derived Measurements of Myosteatosis from Coronary Artery Calcium CT Scans to Predict COPD: The Multi-Ethnic Study of Atherosclerosis
Azimi, A., Atlas, K., Reeves, A. P., Zhang, C., Wasserthal, J., Mirjalili, S. R., Atlas, T., Henschke, C. I., Yankelevitz, D. F., Zulueta, J. J., De-Torres, J. P., Seijo, L. M., Mechanick, J. I., Branch, A., Ma, N., Yip, R., Fan, W., Roy, S. K., Nasir, K. & Molloi, S. & 16 others, , Feb 2026, In: Radiology: Cardiothoracic Imaging. 8, 1, e250205.Research output: Contribution to journal › Article › peer-review
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Coronary Artery Calcium (CAC) Imaging as a Diagnostic Test: Insurance Coverage Implications
Naghavi, M., Wong, N. D., McConnell, M. V., Maron, D. J., Nasir, K., Henschke, C. I., Yankelevitz, D. F., A. Fayad, Z., Vliegenthart, R., Williams, K. A., Mehran, R., Budoff, M., Berman, D., Rana, J. S., Shah, P. K., Kloner, R. A., Narula, J., Greenland, P. & Fuster, V., Feb 2026, In: JACC: Cardiovascular Imaging. 19, 2, p. 266-273 8 p.Research output: Contribution to journal › Editorial
1 Scopus citations
Press/Media
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Heartlung.AI Emerges As A Leading Innovator In Cardiology With 10 Accepted ESC.26 Abstracts
Shah, K., Henschke, C., Mehran,, R., Fayad, Z. & Branch, A.
11/05/26
74 items of Media coverage
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HeartLung Congratulates Scientific Advisor Dr. Claudia Henschke on Receiving 2026 Jacobi Medallion
7/05/26
1 item of Media coverage
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Heartlung Congratulates Scientific Advisor Dr. Claudia Henschke On Receiving 2026 Jacobi Medallion
27/04/26
78 items of Media coverage
Press/Media