Research output per year
Research output per year
Personal profile
Headline
ASSISTANT PROFESSOR | Pharmacological Sciences, ASSISTANT PROFESSOR | Developmental and Regenerative Biology
Biography
Christoph Schaniel is a stem cell biologist focused on understanding the mechanisms of disease pathology (foremost cardiovascular and neurological disorders) and drug action/responses in individuals using human induced pluripotent stem cells with the goal of facilitating the development of precise and personalized therapeutic treatments. For more detailed information, please visit the http://labs.icahn.mssm.edu/schaniellab/ Schaniel Lab website. Research Topics Cardiovascular, Cell Biology, Cellular Differentiation, Developmental Biology, Drug Design and Discovery, Molecular Biology, Stem Cells Multi-Disciplinary Training Areas Biophysics and Systems Pharmacology [BSP], Developmental and Stem Cell Biology [DSCB] Education MS, University of Basel PhD, Basel Institute for Immunology/University of Basel Postdoctoral Fellow, Princeton University Language English
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Collaborations and top research areas from the last five years
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HMGA2 overexpression with specific chromosomal abnormalities predominate in CALR and ASXL1 mutated myelofibrosis: CHRONIC MYELOPROLIFERATIVE NEOPLASMS
Handa, S., Schaniel, C., Tripodi, J., Ahire, D., Mia, M. B., Klingborg, S., Tremblay, D., Marcellino, B. K., Hoffman, R. & Najfeld, V., Mar 2025, In: Leukemia. 39, 3, p. 663-674 12 p., 68.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Reparative immunological consequences of stem cell transplantation as a cellular therapy for refractory Crohn's disease
Guisado, D., Talware, S., Wang, X., Davis, A., Fozilov, E., Etra, A., Colombel, J. F., Schaniel, C., Tastad, C., Levine, J. E., Ferrara, J. L. M., Ling-Shiang, C., Sabic, K., Singh, S., Marcellino, B. K., Hoffman, R., Cho, J. & Cohen, L., 1 Jun 2025, In: Gut. 74, 6, p. 894-905 12 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Multiscale mapping of transcriptomic signatures for cardiotoxic drugs
Hansen, J., Xiong, Y., Siddiq, M. M., Dhanan, P., Hu, B., Shewale, B., Yadaw, A. S., Jayaraman, G., Tolentino, R. E., Chen, Y., Martinez, P., Beaumont, K. G., Sebra, R., Vidovic, D., Schürer, S. C., Goldfarb, J., Gallo, J. M., Birtwistle, M. R., Sobie, E. A. & Azeloglu, E. U. & 5 others, , Dec 2024, In: Nature Communications. 15, 1, 7968.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Sensor macrophages derived from human induced pluripotent stem cells to assess pyrogenic contaminations in parenteral drugs
Abdin, S. M., Mansel, F., Hashtchin, A. R., Ackermann, M., Hansen, G., Becker, B., Kick, B., Pham, N., Dietz, H., Schaniel, C., Martin, U., Spreitzer, I. & Lachmann, N., 1 Jul 2024, In: Biofabrication. 16, 3, 035017.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Ex vivo reprogramming of human hematopoietic stem cells is accompanied by increased transcripts of genes regulating metabolic integrity
Papa, L., Martin, T. C., Djedaini, M., Zangui, M., Ozbek, U., Parsons, R., Hoffman, R. & Schaniel, C., Jun 2023, In: Experimental Hematology. 122, p. 41-54 14 p.Research output: Contribution to journal › Article › peer-review
Open Access
Press/Media
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Data on Myelofibrosis Detailed by Researchers at Icahn School of Medicine at Mount Sinai (Hmga2 Overexpression With Specific Chromosomal Abnormalities Predominate In calr and Asxl1 Mutated Myelofibrosis)
Marcellino, B., Najfeld, V., Hoffman, R., Tremblay, D. & Schaniel, C.
10/01/25
1 item of Media coverage
Press/Media
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Icahn School of Medicine at Mount Sinai Researchers Discuss Research in Science (Multiscale mapping of transcriptomic signatures for cardiotoxic drugs)
DuBois, N., Birtwistle, M., Hansen, J., Sebra, R., Azeloglu, E., Sobie, E., Iyengar, S., Schaniel, C., Goldfarb, J., Gallo, J. & Chen, Y.-B.
2/10/24
1 item of Media coverage
Press/Media
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TD2 To Highlight Development Of A Dual-Specific Inhibitor For Treatment Of Primary Myelofibrosis At ASH Annual Meeting
Hoffman, R., Schaniel, C. & Mascarenhas, J.
5/12/23
64 items of Media coverage
Press/Media
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TD2 To Highlight Development Of A Dual-Specific Inhibitor For Treatment Of Primary Myelofibrosis At ASH Annual Meeting
Hoffman, R., Schaniel, C., Mascarenhas, J. & Murray, M.
5/12/23
1 item of Media coverage
Press/Media
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Reports on Pharmacology Findings from Icahn School of Medicine at Mount Sinai Provide New Insights (Predicting individual-specific cardiotoxicity responses induced by tyrosine kinase inhibitors)
DuBois, N., Birtwistle, M., Azeloglu, E., Sobie, E., Iyengar, S. & Schaniel, C.
21/04/23
1 item of Media coverage
Press/Media