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PROFESSOR | Medicine, Pulmonary, Critical Care and Sleep Medicine
Biography
Charles Powell, MD, is a Professor Medicine and Chief of the Division of Pulmonary, Critical Care and Sleep Medicine. He is also the Director of the Mount Sinai Respiratory Institute. Dr. Powell completed his medical degree at University of Chicago Pritzker School of Medicine, his residency at Columbia Presbyterian Medical Center, and his clinical and research fellowships at Boston University School of Medicine. With clinical and research interests in lung cancer and mesothelioma, Dr. Powell’s investigations center on understanding the genetic and susceptibility factors for these diseases, and the molecular events that are important in the early stages of lung cancer development and progression. His numerous articles and abstracts have been published in journals such as the American Journal of Respiratory and Critical Care Medicine, American Journal of Pathology, CHEST, Cancer, and the American Journal of Respiratory Cell and Molecular Biology. He is Chair of the Thoracic Oncology Section of the American Thoracic Society, an elected member of the Fleischner Society, and a recipient of the American Cancer Society Research Scholar Award.
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Collaborations and top research areas from the last five years
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Association Between Sotatercept and Improved Lung Function in Sarcoidosis-Associated Pulmonary Hypertension
Poor, H. D., Eisenberg, E., Saini, S., Hannah-Clark, S., Zhang, J., Lee, A. G., Serrao, G., Powell, C., Ventetuolo, C. E. & Padilla, M., Jun 2026, In: Chest. 169, 6, p. 1672-1675 4 p.Research output: Contribution to journal › Article › peer-review
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Automated diagnosis of chronic obstructive pulmonary disease using deep learning applied to electrocardiograms
Vaid, A., Sharma, J., Jiang, J., Lampert, J., Sawant, A., Argulian, E., Lerakis, S., Tandon, P., Kovatch, P., Powell, C., Cairns, C. B., Nadkarni, G. N. & Kraft, M., Jan 2026, In: eBioMedicine. 123, 106066.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Characterization of the safety profile of trastuzumab deruxtecan by dose: a pooled analysis across DESTINY studies
Park, Y. H., Cortes, J., Modi, S., Hurvitz, S. A., Bianchini, G., Iwata, H., Shitara, K., Siena, S., Goto, Y., Ku, G. Y., Powell, C. A., Swain, S. M., Arunachalam, M., Janek, M., Cheng, Y., Chu, C., Verma, P., Kuptsova-Clarkson, N., Mathias, E. & Goodman, E. & 1 others, , 1 Jan 2026, In: Oncologist. 31, 1, oyaf396.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Genome-wide Association Study Identifies IL1RL1 and KIAA1217 Associated With Asthma-Chronic Obstructive Pulmonary Disease Overlap in the All of Us Research Program
Li, H., Nadkarni, G. N., Powell, C. A., Kraft, M. & Li, X., Jan 2026, In: Allergy, Asthma and Immunology Research. 18, 1, p. 67-86 20 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Immunopeptidome profiling in pulmonary fibrosis provides a platform for identifying therapeutic targets
Bai, Z., Lan, T., Hong, W., Que, H., Zhu, M., Xiao, X., Wan, D., Ai, J., Huang, S., Wang, J., Hong, Q., Liu, Y., Xiao, C., Zhao, C., Wang, X., Zhang, X., Yang, T., Xu, H., Dai, L. & Powell, C. A. & 6 others, , May 2026, In: Nature Immunology. 27, 5, p. 923-936 14 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations
Press/Media
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Research from Icahn School of Medicine at Mount Sinai Yields New Findings on Chronic Obstructive Pulmonary Disease (Genome-wide Association Study Identifies IL1RL1 and KIAA1217 Associated With Asthma-Chronic Obstructive Pulmonary Disease ...)
Nadkarni, G., Powell, C. & Kraft, M.
10/02/26
1 item of Media coverage
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Researchers from Icahn School of Medicine at Mount Sinai Report on Findings in Chronic Obstructive Pulmonary Disease (Automated Diagnosis of Chronic Obstructive Pulmonary Disease Deep Applied To)
Argulian, E., Nadkarni, G., Kovatch, P., Powell, C., Lerakis, S., Tandon, P. & Kraft, M.
5/02/26
1 item of Media coverage
Press/Media
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Studies from Fudan University Provide New Data on Lung Cancer (PLVAP mediates the regulation of the tumour microenvironment in early-stage lung adenocarcinoma)
Yang, D. & Powell, C.
6/01/26
1 item of Media coverage
Press/Media
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Animate Biosciences Launches Breakthrough Generative AI Platform Revolutionizing Inflammatory and Fibrotic Disease Treatment Through Peptide Therapeutics
13/11/25 → 14/11/25
9 items of Media coverage
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Study Data from Thomas Jefferson University Update Understanding of Lung Cancer (Components Necessary for High-Quality Lung Cancer Screening: A 10-Year Update)
28/10/25
1 item of Media coverage
Press/Media