Boris A. Reva

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Boris A. Reva

PhD

Calculated based on number of publications stored in Pure and citations from Scopus
1990 …2023

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Search results

  • 2023

    Deep learning integrates histopathology and proteogenomics at a pan-cancer level

    Clinical Proteomic Tumor Analysis Consortium, 19 Sep 2023, In: Cell Reports Medicine. 4, 9, 101173.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • Histopathologic and proteogenomic heterogeneity reveals features of clear cell renal cell carcinoma aggressiveness

    Clinical Proteomic Tumor Analysis Consortium, 9 Jan 2023, In: Cancer Cell. 41, 1, p. 139-163.e17

    Research output: Contribution to journal › Article › peer-review

    Open Access
    22 Scopus citations

  • Integrative multi-omic cancer profiling reveals DNA methylation patterns associated with therapeutic vulnerability and cell-of-origin

    Clinical Proteomic Tumor Analysis Consortium, 11 Sep 2023, In: Cancer Cell. 41, 9, p. 1567-1585.e7

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • Pan-cancer analysis of post-translational modifications reveals shared patterns of protein regulation

    Clinical Proteomic Tumor Analysis Consortium, 31 Aug 2023, In: Cell. 186, 18, p. 3945-3967.e26

    Research output: Contribution to journal › Article › peer-review

    Open Access
    2 Scopus citations

  • Pan-cancer proteogenomics connects oncogenic drivers to functional states

    Clinical Proteomic Tumor Analysis Consortium, 31 Aug 2023, In: Cell. 186, 18, p. 3921-3944.e25

    Research output: Contribution to journal › Article › peer-review

    Open Access
    4 Scopus citations

  • Proteogenomic analysis of chemo-refractory high-grade serous ovarian cancer

    Chowdhury, S., Kennedy, J. J., Ivey, R. G., Murillo, O. D., Hosseini, N., Song, X., Petralia, F., Calinawan, A., Savage, S. R., Berry, A. B., Reva, B., Ozbek, U., Krek, A., Ma, W., da Veiga Leprevost, F., Ji, J., Yoo, S., Lin, C., Voytovich, U. J., Huang, Y., & 27 othersLee, S. H., Bergan, L., Lorentzen, T. D., Mesri, M., Rodriguez, H., Hoofnagle, A. N., Herbert, Z. T., Nesvizhskii, A. I., Zhang, B., Whiteaker, J. R., Fenyo, D., McKerrow, W., Wang, J., Schürer, S. C., Stathias, V., Chen, X. S., Barcellos-Hoff, M. H., Starr, T. K., Winterhoff, B. J., Nelson, A. C., Mok, S. C., Kaufmann, S. H., Drescher, C., Cieslik, M., Wang, P., Birrer, M. J. & Paulovich, A. G., 3 Aug 2023, In: Cell. 186, 16, p. 3476-3498.e35

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • Proteogenomic data and resources for pan-cancer analysis

    Clinical Proteomic Tumor Analysis Consortium, 14 Aug 2023, In: Cancer Cell. 41, 8, p. 1397-1406 10 p.

    Research output: Contribution to journal › Review article › peer-review

    Open Access
    5 Scopus citations

  • Proteogenomic insights suggest druggable pathways in endometrial carcinoma

    Clinical Proteomic Tumor Analysis Consortium, 11 Sep 2023, In: Cancer Cell. 41, 9, p. 1586-1605.e15

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • The most likely but largely ignored triggering factor for breast (or all) cancer invasion

    Man, Y. G., Mannion, C., Stojadinovic, A., Peoples, G. E., Cho, W. C. S., Fu, S. W., Tan, X., Hsiao, Y. H., Liu, A., Semczuk, A., Zarogoulidis, P., Gapeev, A. B., Deng, X., Peng, X., Reva, B. A., Omelchenko, T., Wang, J., Song, G. & Chen, T., 2023, In: Journal of Cancer. 14, 4, p. 573-590 18 p.

    Research output: Contribution to journal › Review article › peer-review

    Open Access
  • 2022

    Association between Incidental Pelvic Inflammation and Aggressive Prostate Cancer

    Chakravarty, D., Ratnani, P., Huang, L., Dovey, Z., Sobotka, S., Berryhill, R., Merisaari, H., Al Shaarani, M., Rai, R., Jambor, I., Yadav, K. K., Mittan, S., Parekh, S., Kodysh, J., Wagaskar, V., Brody, R., Cordon-Cardo, C., Rykunov, D., Reva, B., Davicioni, E., & 4 othersWiklund, P., Bhardwaj, N., Nair, S. S. & Tewari, A. K., 1 Jun 2022, In: Cancers. 14, 11, 2734.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    5 Scopus citations

  • Reprogrammed Schwann Cells Organize into Dynamic Tracks that Promote Pancreatic Cancer Invasion

    Deborde, S., Gusain, L., Powers, A., Marcadis, A., Yu, Y., Chen, C. H., Frants, A., Kao, E., Tang, L. H., Vakiani, E., Amisaki, M., Balachandran, V. P., Calo, A., Omelchenko, T., Jessen, K. R., Reva, B. & Wong, R. J., 1 Oct 2022, In: Cancer Discovery. 12, 10, p. 2454-2473 20 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    16 Scopus citations
  • 2021

    A proteogenomic portrait of lung squamous cell carcinoma

    Clinical Proteomic Tumor Analysis Consortium, 5 Aug 2021, In: Cell. 184, 16, p. 4348-4371.e40

    Research output: Contribution to journal › Article › peer-review

    Open Access
    110 Scopus citations

  • Post-anticoagulant d-dimer is a highly prognostic biomarker of covid-19 mortality

    Song, X., Ji, J., Reva, B., Joshi, H., Calinawan, A. P., Mazumdar, M., Wisnivesky, J. P., Taioli, E., Wang, P. & Veluswamy, R. R., 2021, In: ERJ Open Research. 7, 3, 00018-2021.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    7 Scopus citations

  • Proteogenomic and metabolomic characterization of human glioblastoma

    Clinical Proteomic Tumor Analysis Consortium, 12 Apr 2021, In: Cancer Cell. 39, 4, p. 509-528.e20

    Research output: Contribution to journal › Article › peer-review

    Open Access
    230 Scopus citations

  • Proteogenomic insights into the biology and treatment of HPV-negative head and neck squamous cell carcinoma

    Clinical Proteomic Tumor Analysis Consortium, 8 Mar 2021, In: Cancer Cell. 39, 3, p. 361-379.e16

    Research output: Contribution to journal › Article › peer-review

    Open Access
    149 Scopus citations
  • 2020

    Community Assessment of the Predictability of Cancer Protein and Phosphoprotein Levels from Genomics and Transcriptomics

    NCI-CPTAC-DREAM Consortium, 26 Aug 2020, In: Cell Systems. 11, 2, p. 186-195.e9

    Research output: Contribution to journal › Article › peer-review

    Open Access
    13 Scopus citations

  • Erratum: Integrated Proteogenomic Characterization of Clear Cell Renal Cell Carcinoma (Cell (2019) 179(4) (964–983.e31), (S0092867419311237), (10.1016/j.cell.2019.10.007))

    Clinical Proteomic Tumor Analysis Consortium, 9 Jan 2020, In: Cell. 180, 1, p. 207 1 p.

    Research output: Contribution to journal › Comment/debate

    Open Access
    32 Scopus citations

  • Immune Escape in Prostate Cancer: Known and Predicted Mechanisms and Targets

    Reva, B. A., Omelchenko, T., Nair, S. S. & Tewari, A. K., Nov 2020, In: Urologic Clinics of North America. 47, 4, p. e9-e16

    Research output: Contribution to journal › Review article › peer-review

    5 Scopus citations

  • Integrated Proteogenomic Characterization across Major Histological Types of Pediatric Brain Cancer

    Children's Brain Tumor Network & Clinical Proteomic Tumor Analysis Consortium, 23 Dec 2020, In: Cell. 183, 7, p. 1962-1985.e31

    Research output: Contribution to journal › Article › peer-review

    Open Access
    130 Scopus citations

  • Proteogenomic Characterization of Endometrial Carcinoma

    the Clinical Proteomic Tumor Analysis Consortium, 20 Feb 2020, In: Cell. 180, 4, p. 729-748.e26

    Research output: Contribution to journal › Article › peer-review

    Open Access
    217 Scopus citations

  • Proteogenomic Characterization Reveals Therapeutic Vulnerabilities in Lung Adenocarcinoma

    Clinical Proteomic Tumor Analysis Consortium, 9 Jul 2020, In: Cell. 182, 1, p. 200-225.e35

    Research output: Contribution to journal › Article › peer-review

    Open Access
    298 Scopus citations

  • ProTrack: An Interactive Multi-Omics Data Browser for Proteogenomic Studies

    Calinawan, A. P., Song, X., Ji, J., Dhanasekaran, S. M., Petralia, F., Wang, P. & Reva, B., Nov 2020, In: Proteomics. 20, 21-22, 1900359.

    Research output: Contribution to journal › Article › peer-review

    9 Scopus citations
  • 2019

    Integrated Proteogenomic Characterization of Clear Cell Renal Cell Carcinoma

    31 Oct 2019, In: Cell. 179, 4, p. 964-983.e31

    Research output: Contribution to journal › Article › peer-review

    Open Access
    302 Scopus citations

  • Nonsyndromic craniosynostosis: novel coding variants

    Sewda, A., White, S. R., Erazo, M., Hao, K., García-Fructuoso, G., Fernández-Rodriguez, I., Heuzé, Y., Richtsmeier, J. T., Romitti, P. A., Reva, B., Jabs, E. W. & Peter, I., 1 Mar 2019, In: Pediatric Research. 85, 4, p. 463-468 6 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    9 Scopus citations
  • 2018

    Detection of endometrial precancer by a targeted gynecologic cancer liquid biopsy

    Martignetti, J. A., Pandya, D., Nagarsheth, N., Chen, Y., Camacho, O., Tomita, S., Brodman, M., Ascher-Walsh, C., Kolev, V., Cohen, S., Harkins, T. T., Schadt, E. E., Reva, B., Sebra, R. & Dottino, P., Dec 2018, In: Cold Spring Harbor molecular case studies. 4, 6, a003269.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    11 Scopus citations
  • 2017

    Identification and functional characterization of EGFR V769M, a novel germline variant associated with multiple lung adenocarcinomas

    Hellmann, M. D., Hayashi, T., Reva, B., Yu, H. A., Riely, G. J., Adusumilli, P. S., Travis, W. D., Wilkins, O., Bramletta, N., Chandramohan, R., Fleischut, M. H., Kris, M. G., Robson, M. E., Arcila, M. E., Paik, P. K. & Ladanyi, M., 2017, In: JCO Precision Oncology. 2017, 1, p. 1-10 10 p.

    Research output: Contribution to journal › Article › peer-review

    9 Scopus citations

  • Insights into beta cell regeneration for diabetes via integration of molecular landscapes in human insulinomas

    Wang, H., Bender, A., Wang, P., Karakose, E., Inabnet, W. B., Libutti, S. K., Arnold, A., Lambertini, L., Stang, M., Chen, H., Kasai, Y., Mahajan, M., Kinoshita, Y., Fernandez-Ranvier, G., Becker, T. C., Takane, K. K., Walker, L. A., Saul, S., Chen, R., Scott, D. K., & 9 othersFerrer, J., Antipin, Y., Donovan, M., Uzilov, A. V., Reva, B., Schadt, E. E., Losic, B., Argmann, C. & Stewart, A. F., 1 Dec 2017, In: Nature Communications. 8, 1, 767.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    66 Scopus citations
  • 2016

    A new molecular signature method for prediction of driver cancer pathways from transcriptional data

    Rykunov, D., Beckmann, N. D., Li, H., Uzilov, A., Schadt, E. E. & Reva, B., 20 Jun 2016, In: Nucleic Acids Research. 44, 11, e110.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    14 Scopus citations

  • Development and clinical application of an integrative genomic approach to personalized cancer therapy

    Uzilov, A. V., Ding, W., Fink, M. Y., Antipin, Y., Brohl, A. S., Davis, C., Lau, C. Y., Pandya, C., Shah, H., Kasai, Y., Powell, J., Micchelli, M., Castellanos, R., Zhang, Z., Linderman, M., Kinoshita, Y., Zweig, M., Raustad, K., Cheung, K., Castillo, D., & 24 othersWooten, M., Bourzgui, I., Newman, L. C., Deikus, G., Mathew, B., Zhu, J., Glicksberg, B. S., Moe, A. S., Liao, J., Edelmann, L., Dudley, J. T., Maki, R. G., Kasarskis, A., Holcombe, R. F., Mahajan, M., Hao, K., Reva, B., Longtine, J., Starcevic, D., Sebra, R., Donovan, M. J., Li, S., Schadt, E. E. & Chen, R., 2016, In: Genome Medicine. 8, 1, 62.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    68 Scopus citations

  • Genomic Analysis of Uterine Lavage Fluid Detects Early Endometrial Cancers and Reveals a Prevalent Landscape of Driver Mutations in Women without Histopathologic Evidence of Cancer: A Prospective Cross-Sectional Study

    Nair, N., Camacho-Vanegas, O., Rykunov, D., Dashkoff, M., Camacho, S. C., Schumacher, C. A., Irish, J. C., Harkins, T. T., Freeman, E., Garcia, I., Pereira, E., Kendall, S., Belfer, R., Kalir, T., Sebra, R., Reva, B., Dottino, P. & Martignetti, J. A., Dec 2016, In: PLoS Medicine. 13, 12, e1002206.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    74 Scopus citations

  • Mutation Screening of Candidate Genes in Patients with Nonsyndromic Sagittal Craniosynostosis

    Ye, X., Guilmatre, A., Reva, B., Peter, I., Heuzé, Y., Richtsmeier, J. T., Fox, D. J., Goedken, R. J., Jabs, E. W. & Romitti, P. A., 1 Mar 2016, In: Plastic and Reconstructive Surgery. 137, 3, p. 952-961 10 p.

    Research output: Contribution to journal › Article › peer-review

    19 Scopus citations

  • Strand-specific in vivo screen of cancer-associated miRNAs unveils a role for miR-21-in SCC progression

    Ge, Y., Zhang, L., Nikolova, M., Reva, B. & Fuchs, E., 1 Jan 2016, In: Nature Cell Biology. 18, 1, p. 111-121 11 p.

    Research output: Contribution to journal › Article › peer-review

    50 Scopus citations
  • 2015

    Comprehensive genomic characterization of head and neck squamous cell carcinomas

    The Cancer Genome Atlas Network, 29 Jan 2015, In: Nature. 517, 7536, p. 576-582 7 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    2745 Scopus citations

  • MAP2K1 (MEK1) mutations define a distinct subset of lung adenocarcinoma associated with smoking

    Arcila, M. E., Drilon, A., Sylvester, B. E., Lovly, C. M., Borsu, L., Reva, B., Kris, M. G., Solit, D. B. & Ladanyi, M., 15 Apr 2015, In: Clinical Cancer Research. 21, 8, p. 1935-1943 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    109 Scopus citations
  • 2014

    Clinical and in vivo evidence that EGFR S768I mutant lung adenocarcinomas are sensitive to erlotinib

    Hellmann, M. D., Reva, B., Yu, H., Rusch, V. W., Rizvi, N. A., Kris, M. G. & Arcila, M. E., 1 Oct 2014, In: Journal of Thoracic Oncology. 9, 10, p. e73-e74

    Research output: Contribution to journal › Article › peer-review

    Open Access
    23 Scopus citations

  • Comprehensive molecular characterization of urothelial bladder carcinoma

    Weinstein, J. N., Akbani, R., Broom, B. M., Wang, W., Verhaak, R. G. W., McConkey, D., Lerner, S., Morgan, M., Creighton, C. J., Smith, C., Cherniack, A. D., Kim, J., Pedamallu, C. S., Noble, M. S., Al-Ahmadie, H. A., Reuter, V. E., Rosenberg, J. E., F.Bajorin, D., Bochner, B. H., Solit, D. B., & 273 othersKoppie, T., Robinson, B., Gordenin, D. A., Fargo, D., Klimczak, L. J., Roberts, S. A., Au, J., Laird, P. W., Hinoue, T., Schultz, N., Ramirez, R., Hansel, D., Hoadley, K. A., Kim, W. Y., Damrauer, J. S., Baylin, S. B., Mungall, A. J., Robertson, A. G., Chu, A., Kwiatkowski, D. J., Sougnez, C., Cibulskis, K., Lichtenstein, L., Sivachenko, A., Stewart, C., Lawrence, M. S., Getz, G., Lander, E., Gabrie, S. B., Donehower, L., Carter, S. L., Saksena, G., Schumacher, S. E., Freeman, S. S., Jung, J., Bhatt, A. S., Pugh, T., Beroukhim, R., Meyerson, M., Ally, A., Balasundaram, M., Butterfield, Y. S. N., Dhalla, N., Hirst, C., Holt, R. A., Jones, S. J. M., Lee, D., Li, H. I., Marra, M. A., Mayo, M., Moore, R. A., Schein, J. E., Sipahimalani, P., Tam, A., Thiessen, N., Wong, T., Wye, N., Bowlby, R., Chuah, E., Guin, R., Shen, H., Bootwalla, M. S., Triche, T., Lai, P. H., Van Den Berg, D. J., Weisenberger, D. J., Balu, S., Bodenheimer, T., Hoyle, A. P., Jefferys, S. R., Meng, S., Mose, L. E., Simons, J. V., Soloway, M. G., Wu, J., Parker, J. S., Hayes, D. N., Roach, J., Buda, E., Jones, C. D., Mieczkowski, P. A., Tan, D., Veluvolu, U., Waring, S., Auman, J. T., Perou, C. M., Wilkerson, M. D., Santoso, N., Parfenov, M., Ren, X., Pantazi, A., Hadjipanayis, A., Seidman, J., Kucherlapati, R., Lee, S., Yang, L., Park, P. J., Xu, A. W., Protopopov, A., Zhang, J., Bristow, C., Mahadeshwar, H. S., Seth, S., Song, X., Tang, J., Zeng, D., Chin, L., Guo, C., Casasent, T. D., Liu, W., Ju, Z., Motter, T., Peng, B., Ryan, M., Su, X., Yang, J. Y., Lorenzi, P. L., Yao, H., Zhang, N., Zhang, J., Mills, G. B., Cho, J., DiCara, D., Frazer, S., Gehlenborg, N., Heiman, D. I., Lin, P., Liu, Y., Stojanov, P., Voet, D., Zhang, H., Zou, L., Bernard, B., Kreisberg, D., Reynolds, S., Rovira, H., Shmulevich, I., Gao, J., Jacobsen, A., Aksoy, B. A., Antipin, Y., Ciriello, G., Dresdner, G., Gross, B., Lee, W., Reva, B., Shen, R., Sinha, R., Sumer, S. O., Weinhold, N., Ladanyi, M., Sander, C., Benz, C., Carlin, D., Haussler, D., Ng, S., Paull, E., Stuart, J., Zhu, J., Liu, Y., Zhang, W., Taylor, B. S., Lichtenberg, T. M., Zmuda, E., Barr, T., Black, A. D., George, M., Hanf, B., Helsel, C., McAllister, C., Ramirez, N. C., Tabler, T. R., Weaver, S., Wise, L., Bowen, J., Gastier-Foster, J. M., Jian, W., Tello, S., Ittman, M., Castro, P., McClenden, W. D., Gibbs, R., Saller, C., Tarvin, K., DiPiero, J. M., Owens, J., Bollag, R., Li, Q., Weinberger, P., Czerwinski, C., Huelsenbeck-Dill, L., Iacocca, M., Petrelli, N., Rabeno, B., Swanson, P., Shelton, T., Curley, E., Gardner, J., Mallery, D., Penny, R., Van Bang, N., Hanh, P. T., Kohl, B., Van Le, X., Phu, B. D., Thorp, R., Tien, N. V., Vinh, L. Q., Sandusky, G., Burks, E., Christ, K., Gee, J., Holway, A., Moinzadeh, A., Sorcini, A., Sullivan, T., Garcia-Grossman, I. R., Regazzi, A. M., Boice, L., Rathmell, W. K., Thorne, L., Bastacky, S., Davies, B., Dhir, R., Gingrich, J., Hrebinko, R., Maranchie, J., Nelson, J., Parwani, A., Bshara, W., Gaudioso, C., Morrison, C., Alexopoulou, V., Bartlett, J., Engel, J., Kodeeswaran, S., Antic, T., O'Donnell, P. H., Smith, N. D., Steinberg, G. D., Egea, S., Gomez-Fernandez, C., Herbert, L., Jorda, M., Soloway, M., Beaver, A., Carter, S., Kapur, P., Lewis, C., Lotan, Y., Bondaruk, J., Czerniak, B., Skinner, E., Aldape, K., Jensen, M. A., Kahn, A. B., Pihl, T. D., Pot, D. A., Srinivasan, D., Wan, Y., Ferguson, M. L., Zenklusen, J. C., Davidsen, T., Demchok, J. A., Shaw, K. R. M., Sheth, M., Tarnuzzer, R., Wang, Z., Yang, L., Hutter, C., Ozenberger, B. A., Sofia, H. J. & Eley, G., 2014, In: Nature. 507, 7492, p. 315-322 8 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    2251 Scopus citations

  • Comprehensive molecular profiling of lung adenocarcinoma: The cancer genome atlas research network

    Collisson, E. A., Campbell, J. D., Brooks, A. N., Berger, A. H., Lee, W., Chmielecki, J., Beer, D. G., Cope, L., Creighton, C. J., Danilova, L., Ding, L., Getz, G., Hammerman, P. S., Hayes, D. N., Hernandez, B., Herman, J. G., Heymach, J. V., Jurisica, I., Kucherlapati, R., Kwiatkowski, D., & 290 othersLadanyi, M., Robertson, G., Schultz, N., Shen, R., Sinha, R., Sougnez, C., Tsao, M. S., Travis, W. D., Weinstein, J. N., Wigle, D. A., Wilkerson, M. D., Chu, A., Cherniack, A. D., Hadjipanayis, A., Rosenberg, M., Weisenberger, D. J., Laird, P. W., Radenbaugh, A., Ma, S., Stuart, J. M., Byers, L. A., Baylin, S. B., Govindan, R., Meyerson, M., Gabriel, S. B., Cibulskis, K., Kim, J., Stewart, C., Lichtenstein, L., Lander, E. S., Lawrence, M. S., Getz, E., Fulton, R., Fulton, L. L., McLellan, M. D., Wilson, R. K., Ye, K., Fronick, C. C., Maher, C. A., Miller, C. A., Wendl, M. C., Cabanski, C., Mardis, E., Wheeler, D., Balasundaram, M., Butterfield, Y. S. N., Carlsen, R., Chuah, E., Dhalla, N., Guin, R., Hirst, C., Lee, D., Li, H. I., Mayo, M., Moore, R. A., Mungall, A. J., Schein, J. E., Sipahimalani, P., Tam, A., Varhol, R., Robertson, A. G., Wye, N., Thiessen, N., Holt, R. A., Jones, S. J. M., Marra, M. A., Imielinski, M., Onofrio, R. C., Hodis, E., Zack, T., Helman, E., Pedamallu, C. S., Mesirov, J., Saksena, G., Schumacher, S. E., Carter, S. L., Garraway, L., Beroukhim, R., Lee, S., Mahadeshwar, H. S., Pantazi, A., Protopopov, A., Ren, X., Seth, S., Song, X., Tang, J., Yang, L., Zhang, J., Chen, P. C., Parfenov, M., Xu, A. W., Santoso, N., Chin, L., Park, P. J., Hoadley, K. A., Auman, J. T., Meng, S., Shi, Y., Buda, E., Waring, S., Veluvolu, U., Tan, D., Mieczkowski, P. A., Jones, C. D., Simons, J. V., Soloway, M. G., Bodenheimer, T., Jefferys, S. R., Roach, J., Hoyle, A. P., Wu, J., Balu, S., Singh, D., Prins, J. F., Marron, J. S., Parker, J. S., Perou, C. M., Liu, J., Maglinte, D. T., Lai, P. H., Bootwalla, M. S., Van Den Berg, D. J., Triche, T., Cho, J., DiCara, D., Heiman, D., Lin, P., Mallard, W., Voet, D., Zhang, H., Zou, L., Noble, M. S., Gehlenborg, N., Thorvaldsdottir, H., Nazaire, M. D., Robinson, J., Aksoy, B. A., Ciriello, G., Taylor, B. S., Dresdner, G., Gao, J., Gross, B., Seshan, V. E., Reva, B., Sumer, S. O., Weinhold, N., Sander, C., Ng, S., Zhu, J., Benz, C. C., Yau, C., Haussler, D., Spellman, P. T., Kimes, P. K., Broom, B. M., Wang, J., Lu, Y., Ng, P. K. S., Diao, L., Liu, W., Amos, C. I., Akbani, R., Mills, G. B., Curley, E., Paulauskis, J., Lau, K., Morris, S., Shelton, T., Mallery, D., Gardner, J., Penny, R., Saller, C., Tarvin, K., Richards, W. G., Cerfolio, R., Bryant, A., Raymond, D. P., Pennell, N. A., Farver, C., Czerwinski, C., Huelsenbeck-Dill, L., Iacocca, M., Petrelli, N., Rabeno, B., Brown, J., Bauer, T., Dolzhanskiy, C. O., Potapova, O., Rotin, D., Voronina, O., Nemirovich-Danchenko, E., Fedosenko, K. V., Gal, A., Behera, M., Ramalingam, S. S., Sica, G., Flieder, D., Boyd, J., Weaver, J. E., Kohl, B., Thinh, D. H. Q., Sandusky, G., Juhl, H., Duhig, E., Illei, P., Gabrielson, E., Shin, J., Lee, B., Rogers, K., Trusty, D., Brock, M. V., Williamson, C., Burks, E., Rieger-Christ, K., Holway, A., Sullivan, T., Asiedu, M. K., Kosari, F., Rekhtman, N., Zakowski, M., Rusch, V. W., Zippile, P., Suh, J., Pass, H., Goparaju, C., Owusu-Sarpong, Y., Bartlett, J. M. S., Kodeeswaran, S., Parfitt, J., Sekhon, H., Albert, M., Eckman, J., Myers, J. B., Morrison, C., Gaudioso, C., Borgia, J. A., Bonomi, P., Pool, M., Liptay, M. J., Moiseenko, F., Zaytseva, I., Dienemann, H., Meister, M., Schnabel, P. A., Muley, T. R., Peifer, M., Gomez-Fernandez, C., Herbert, L., Egea, S., Huang, M., Thorne, L. B., Boice, L., Salazar, A. H., Funkhouser, W. K., Rathmell, W. K., Dhir, R., Yousem, S. A., Dacic, S., Schneider, F., Siegfried, J. M., Hajek, R., Watson, M. A., McDonald, S., Meyers, B., Clarke, B., Yang, I. A., Fong, K. M., Hunter, L., Windsor, M., Bowman, R. V., Peters, S., Letovanec, I., Khan, K. Z., Jensen, M. A., Snyder, E. E., Srinivasan, D., Kahn, A. B., Baboud, J., Pot, D. A., Shaw, K. R. M., Sheth, M., Davidsen, T., Demchok, J. A., Yang, L., Wang, Z., Tarnuzzer, R., Zenklusen, J. C., Ozenberger, B. A., Sofia, H. J. & Cheney, R., 2014, In: Nature. 511, 7511, p. 543-550 8 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    3842 Scopus citations

  • Direct in vivo RNAi screen unveils myosin IIa as a tumor suppressor of squamous cell carcinomas

    Schramek, D., Sendoel, A., Segal, J. P., Beronja, S., Heller, E., Oristian, D., Reva, B. & Fuchs, E., 2014, In: Science. 343, 6168, p. 309-313 5 p.

    Research output: Contribution to journal › Article › peer-review

    201 Scopus citations

  • Genetic variation in DNA repair pathways and risk of non-Hodgkin's lymphoma

    Rendleman, J., Antipin, Y., Reva, B., Adaniel, C., Przybylo, J. A., Dutra-Clarke, A., Hansen, N., Heguy, A., Huberman, K., Borsu, L., Paltiel, O., Ben-Yehuda, D., Brown, J. R., Freedman, A. S., Sander, C., Zelenetz, A., Klein, R. J., Shao, Y., Lacher, M., Vijai, J., & 2 othersOffit, K. & Kirchhoff, T., 10 Jul 2014, In: PLoS ONE. 9, 7, e101685.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    18 Scopus citations

  • Multiplatform analysis of 12 cancer types reveals molecular classification within and across tissues of origin

    The Cancer Genome Atlas Research Network, 14 Aug 2014, In: Cell. 158, 4, p. 929-944 16 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    1068 Scopus citations

  • Unsuspected collision of synchronous lung adenocarcinomas: A potential cause of aberrant driver mutation profiles

    Rekhtman, N., Borsu, L., Reva, B., Arcila, M., Riely, G. J., Ladanyi, M. & Drilon, A., Jan 2014, In: Journal of Thoracic Oncology. 9, 1, p. e1-e3

    Research output: Contribution to journal › Article › peer-review

    Open Access
    6 Scopus citations
  • 2013

    Adverse outcomes in clear cell renal cell carcinoma with mutations of 3p21 epigenetic regulators BAP1 and SETD2: A report by MSKCC and the KIRC TCGA research network

    Hakimi, A. A., Ostrovnaya, I., Reva, B., Schultz, N., Chen, Y. B., Gonen, M., Liu, H., Takeda, S., Voss, M. H., Tickoo, S. K., Reuter, V. E., Russo, P., Cheng, E. H., Sander, C., Motzer, R. J. & Hsieh, J. J., 15 Jun 2013, In: Clinical Cancer Research. 19, 12, p. 3259-3267 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    267 Scopus citations

  • Comprehensivemolecular characterization of clear cell renal cell carcinoma

    Creighton, C. J., Morgan, M., Gunaratne, P. H., Wheeler, D. A., Gibbs, R. A., Robertson, G., Chu, A., Beroukhim, R., Cibulskis, K., Signoretti, S., Vandin, F., Wu, H. T., Raphael, B. J., Verhaak, R. G. W., Tamboli, P., Torres-Garcia, W., Akbani, R., Weinstein, J. N., Reuter, V., Hsieh, J. J., & 268 othersBrannon, A. R., Hakimi, A. A., Jacobsen, A., Ciriello, G., Reva, B., Ricketts, C. J., Linehan, W. M., Stuart, J. M., Rathmell, W. K., Hui, S., Laird, P. W., Muzny, D., Davis, C., Liu, X., Chang, K., Kakkar, N., Treviño, L. R., Benton, S., Reid, J. G., Morton, D., Doddapaneni, H., Yi, H., Lewis, L., Huyen, D., Kovar, C., Zhu, Y., Santibanez, J., Min, W., Hale, W., Kalra, D., Getz, G., Lawrence, M. S., Sougnez, C., Carter, S. L., Sivachenko, A., Lee, L., Stewart, C., Voet, D., Fisher, S., Gabriel, S. B., Lander, E., Schumacher, S. E., Tabak, B., Saksena, G., Onofrio, R. C., Cherniack, A. D., Gentry, J., Ardlie, K., Meyerson, M., Chun, H. J. E., Mungall, A. J., Sipahimalani, P., Stoll, D., Ally, A., Balasundaram, M., Butterfield, Y. S. N., Carlsen, R., Carter, C., Chuah, E., Coope, R. J. N., Dhalla, N., Gorski, S., Guin, R., Hirst, C., Hirst, M., Holt, R. A., Lebovitz, C., Lee, D., Li, H. I., Mayo, M., Moore, R. A., Pleasance, E., Plettner, P., Schein, J. E., Shafiei, A., Slobodan, J. R., Tam, A., Thiessen, N., Varhol, R. J., Wye, N., Zhao, Y., Birol, I., Jones, S. J. M., Marra, M. A., Auman, J. T., Tan, D., Jones, C. D., Hoadley, K. A., Mieczkowski, P. A., Mose, L. E., Jefferys, S. R., Topal, M. D., Liquori, C., Turman, Y. J., Yan, S., Waring, S., Buda, E., Walsh, J., Wu, J., Bodenheimer, T., Hoyle, A. P., Simons, J. V., Soloway, M. G., Balu, S., Parker, J. S., Hayes, D. N., Perou, C. M., Kucherlapati, R., Park, P., Triche, T., Weisenberger, D. J., Lai, P. H., Bootwalla, M. S., Maglinte, D. T., Mahurkar, S., Berman, B. P., Van Den Berg, D. J., Cope, L., Baylin, S. B., Noble, M. S., DiCara, D., Zhang, H., Cho, J., Heiman, D. I., Gehlenborg, N., Mallard, W., Pei, L., Frazer, S., Stojanov, P., Liu, Y., Zhou, L., Kim, J., Chin, L., Benz, C., Yau, C., Reynolds, S. M., Shmulevich, I., Vegesna, R., Kim, H., Wei, Z., Cogdell, D., Jonasch, E., Ding, Z., Lu, Y., Zhang, N., Unruh, A. K., Casasent, T. D., Wakefield, C., Tsavachidou, D., Mills, G. B., Gao, J., Cerami, E., Gross, B., Aksoy, B. A., Sinha, R., Weinhold, N., Sumer, S. O., Taylor, B. S., Shen, R., Ostrovnaya, I., Berger, M. F., Ladanyi, M., Sander, C., Fei, S. S., Stout, A., Spellman, P. T., Rubin, D. L., Liu, T. T., Sam, N., Paull, E. O., Carlin, D., Goldstein, T., Waltman, P., Ellrott, K., Jing, Z., Haussler, D., Xiao, W., Shelton, C., Gardner, J., Penny, R., Sherman, M., Mallery, D., Morris, S., Paulauskis, J., Burnett, K., Shelton, T., Kaelin, W. G., Choueiri, T., Atkins, M. B., Curley, E., Tickoo, S., Thorne, L., Boice, L., Mei, H., Fisher, J. C., Vocke, C. D., Peterson, J., Worrell, R., Merino, M. J., Schmidt, L. S., Czerniak, B. A., Aldape, K. D., Wood, C. G., Boyd, J., Weaver, J. E., Iacocca, M. V., Petrelli, N., Witkin, G., Brown, J., Czerwinski, C., Huelsenbeck-Dill, L., Rabeno, B., Myers, J., Morrison, C., Bergsten, J., Eckman, J., Harr, J., Smith, C., Tucker, K., Zach, L. A., Bshara, W., Gaudioso, C., Dhir, R., Maranchie, J., Nelson, J., Parwani, A., Potapova, C. O., Fedosenko, K., Cheville, J. C., Thompson, R. H., Mosquera, J. M., Rubin, M. A., Blute, M. L., Pihl, T., Jensen, M., Sfeir, R., Kahn, A., Chu, A., Kothiyal, P., Snyder, E., Pontius, J., Ayala, B., Backus, M., Walton, J., Baboud, J., Berton, D., Nicholls, M., Srinivasan, D., Raman, R., Girshik, S., Kigonya, P., Alonso, S., Sanbhadti, R., Barletta, S., Pot, D., Sheth, M., Demchok, J. A., Davidsen, T., Wang, Z., Yang, L., Tarnuzzer, R. W., Zhang, J., Eley, G., Ferguson, M. L., Mills Shaw, K. R., Guyer, M. S., Ozenberger, B. A. & Sofia, H. J., 2013, In: Nature. 499, 7456, p. 43-49 7 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    2438 Scopus citations

  • Computational approaches to identify functional genetic variants in cancer genomes

    Gonzalez-Perez, A., Mustonen, V., Reva, B., Ritchie, G. R. S., Creixell, P., Karchin, R., Vazquez, M., Fink, J. L., Kassahn, K. S., Pearson, J. V., Bader, G. D., Boutros, P. C., Muthuswamy, L., Ouellette, B. F. F., Reimand, J., Linding, R., Shibata, T., Valencia, A., Butler, A., Dronov, S., & 8 othersFlicek, P., Shannon, N. B., Carter, H., Li, D., Sander, C., Stuart, J. M., Stein, L. D. & Lopez-Bigas, N., Aug 2013, In: Nature Methods. 10, 8, p. 723-729 7 p.

    Research output: Contribution to journal › Review article › peer-review

    131 Scopus citations

  • EGFR exon 20 insertion mutations in lung adenocarcinomas: Prevalence, molecular heterogeneity, and clinicopathologic characteristics

    Arcila, M. E., Nafa, K., Chaft, J. E., Rekhtman, N., Lau, C., Reva, B. A., Zakowski, M. F., Kris, M. G. & Ladanyi, M., Feb 2013, In: Molecular Cancer Therapeutics. 12, 2, p. 220-229 10 p.

    Research output: Contribution to journal › Article › peer-review

    349 Scopus citations

  • Identification of a pan-cancer oncogenic microRNA superfamily anchored by a central core seed motif

    Hamilton, M. P., Rajapakshe, K., Hartig, S. M., Reva, B., McLellan, M. D., Kandoth, C., Ding, L., Zack, T. I., Gunaratne, P. H., Wheeler, D. A., Coarfa, C. & McGuire, S. E., 2013, In: Nature Communications. 4, 2730.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    93 Scopus citations

  • Integrated genomic characterization of endometrial carcinoma

    Getz, G., Gabriel, S. B., Cibulskis, K., Lander, E., Sivachenko, A., Sougnez, C., Lawrence, M., Kandoth, C., Dooling, D., Fulton, R., Fulton, L., Kalicki-Veizer, J., McLellan, M. D., O'Laughlin, M., Schmidt, H., Wilson, R. K., Ye, K., Li, D., Ally, A., Balasundaram, M., & 256 othersBirol, I., Butterfield, Y. S. N., Carlsen, R., Carter, C., Chu, A., Chuah, E., Chun, H. J. E., Dhalla, N., Guin, R., Hirst, C., Holt, R. A., Jones, S. J. M., Lee, D., Li, H. I., Marra, M. A., Mayo, M., Moore, R. A., Mungall, A. J., Plettner, P., Schein, J. E., Sipahimalani, P., Tam, A., Varhol, R. J., Gordon Robertson, A., Cherniack, A. D., Pashtan, I., Saksena, G., Onofrio, R. C., Schumacher, S. E., Tabak, B., Carter, S. L., Hernandez, B., Gentry, J., Salvesen, H. B., Ardlie, K., Winckler, W., Beroukhim, R., Meyerson, M., Hadjipanayis, A., Lee, S., Mahadeshwar, H. S., Park, P., Protopopov, A., Ren, X., Seth, S., Song, X., Tang, J., Xi, R., Yang, L., Dong, Z., Kucherlapati, R., Chin, L., Zhang, J., Todd Auman, J., Balu, S., Bodenheimer, T., Buda, E., Neil Hayes, D., Hoyle, A. P., Jefferys, S. R., Jones, C. D., Meng, S., Mieczkowski, P. A., Mose, L. E., Parker, J. S., Perou, C. M., Roach, J., Yan, S., Simons, J. V., Soloway, M. G., Tan, D., Topal, M. D., Waring, S., Wu, J., Hoadley, K. A., Baylin, S. B., Bootwalla, M. S., Lai, P. H., Triche, T. J., Van Den Berg, D. J., Weisenberger, D. J., Laird, P. W., Shen, H., Cho, J., Dicara, D., Frazer, S., Heiman, D., Jing, R., Lin, P., Mallard, W., Stojanov, P., Voet, D., Zhang, H., Zou, L., Noble, M., Reynolds, S. M., Shmulevich, I., Arman Aksoy, B., Antipin, Y., Ciriello, G., Dresdner, G., Gao, J., Gross, B., Jacobsen, A., Ladanyi, M., Reva, B., Sander, C., Sinha, R., Onur Sumer, S., Taylor, B. S., Cerami, E., Weinhold, N., Schultz, N., Shen, R., Benz, S., Goldstein, T., Haussler, D., Ng, S., Szeto, C., Stuart, J., Benz, C. C., Yau, C., Zhang, W., Annala, M., Broom, B. M., Casasent, T. D., Ju, Z., Liang, H., Liu, G., Lu, Y., Unruh, A. K., Wakefield, C., Weinstein, J. N., Zhang, N., Liu, Y., Broaddus, R., Akbani, R., Mills, G. B., Adams, C., Barr, T., Black, A. D., Bowen, J., Deardurff, J., Frick, J., Gastier-Foster, J. M., Grossman, T., Harper, H. A., Hart-Kothari, M., Helsel, C., Hobensack, A., Kuck, H., Kneile, K., Leraas, K. M., Lichtenberg, T. M., McAllister, C., Pyatt, R. E., Ramirez, N. C., Tabler, T. R., Vanhoose, N., White, P., Wise, L., Zmuda, E., Barnabas, N., Berry-Green, C., Blanc, V., Boice, L., Button, M., Farkas, A., Green, A., MacKenzie, J., Nicholson, D., Kalloger, S. E., Blake Gilks, C., Karlan, B. Y., Lester, J., Orsulic, S., Borowsky, M., Cadungog, M., Czerwinski, C., Huelsenbeck-Dill, L., Iacocca, M., Petrelli, N., Rabeno, B., Witkin, G., Nemirovich-Danchenko, E., Potapova, O., Rotin, D., Berchuck, A., Birrer, M., Disaia, P., Monovich, L., Curley, E., Gardner, J., Mallery, D., Penny, R., Dowdy, S. C., Winterhoff, B., Dao, L., Gostout, B., Meuter, A., Teoman, A., Dao, F., Olvera, N., Bogomolniy, F., Garg, K., Soslow, R. A., Abramov, M., Bartlett, J. M. S., Kodeeswaran, S., Parfitt, J., Moiseenko, F., Clarke, B. A., Goodman, M. T., Carney, M. E., Matsuno, R. K., Fisher, J., Huang, M., Kimryn Rathmell, W., Thorne, L., Van Le, L., Dhir, R., Edwards, R., Elishaev, E., Zorn, K., Goodfellow, P. J., Mutch, D., Kahn, A. B., Bell, D. W., Pollock, P. M., Wang, C., Wheeler, D., Shinbrot, E., Gordon Robertson, A., Ding, L., Blake Gilks, C., Mardis, E. R., Ayala, B., Chu, A. L., Jensen, M. A., Kothiyal, P., Pihl, T. D., Pontius, J., Pot, D. A., Snyder, E. E., Srinivasan, D., Mills Shaw, K. R., Sheth, M., Davidsen, T., Eley, G., Ferguson, M. L., Yang, L., Guyer, M. S., Ozenberger, B. A., Sofia, H. J., Gordon Robertson, A. & Levine, D. A., 2013, In: Nature. 497, 7447, p. 67-73 7 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    3420 Scopus citations

  • Revealing selection in cancer using the predicted functional impact of cancer mutations. Application to nomination of cancer drivers.

    Reva, B., 2013, In: Unknown Journal. 14 Suppl 3

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    Open Access
    8 Scopus citations

  • The cancer genome atlas pan-cancer analysis project

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    Research output: Contribution to journal › Article › peer-review

    Open Access
    97 Scopus citations