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AN INTEGRATED PLATFORM FOR NOVEL PERSONALIZED LIVER CANCER THERAPEUTICS
Dar, A., Guccione, E., Lujambio, A., Guccione, E. E., Guccione, E. & Lujambio, A.
1/07/21 → 30/06/23
Project: Research
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A Chemical Genetic Approach to Exploring Novel Therapeutic Space for Colorectal Cancer
Dar, A., Cagan, R., Dar, A. & Cagan, R. R. L.
1/03/21 → 28/02/23
Project: Research
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IND-Enabling Studies for WNTinib, a Novel Selective Therapeutic for CTNNB1 Mutant Hepatoblastomas
Guccione, E., Llovet, J. J. & Dar, A.
Alex's Lemonade Stand Foundation for Childhood Cancer
1/01/21 → …
Project: Research
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Targeting Oncogenic Ras-MAPK Signaling Complexes via the Scaffold KSR
15/03/18 → 28/02/23
Project: Research
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An Antagonist of KSR1-Driven Adaptive Resistance to Clinical RAS-MAPK Inhibitors
Chow, A., Yerabolu, J. R., Reyes, K., Scopton, A. & Dar, A. C., 1 May 2022, In: FASEB Journal. 36Research output: Contribution to journal › Article › peer-review
Open Access -
Conformational control and regulation of the pseudokinase KSR via small molecule binding interactions
Chow, A., Khan, Z. M., Marsiglia, W. M. & Dar, A. C., Jan 2022, Pseudokinases. Jura, N. & Murphy, J. M. (eds.). Academic Press Inc., p. 365-402 38 p. (Methods in Enzymology; vol. 667).Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
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Rapid, scalable assessment of SARS-CoV-2 cellular immunity by whole-blood PCR
Schwarz, M., Torre, D., Lozano-Ojalvo, D., Tan, A. T., Tabaglio, T., Mzoughi, S., Sanchez-Tarjuelo, R., Le Bert, N., Lim, J. M. E., Hatem, S., Tuballes, K., Camara, C., Lopez-Granados, E., Paz-Artal, E., Correa-Rocha, R., Ortiz, A., Lopez-Hoyos, M., Portoles, J., Cervera, I., Gonzalez-Perez, M., & 34 others , Nov 2022, In: Nature Biotechnology. 40, 11, p. 1680-1689 10 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
RASopathy mutations open new insights into the mechanism of BRAF activation
Dar, A. C. & Brady, D. C., 17 Nov 2022, In: Molecular Cell. 82, 22, p. 4192-4193 2 p.Research output: Contribution to journal › Comment/debate
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Targeting drug-resistant mutations in ALK
He, L. & Dar, A. C., Jun 2022, In: Nature Cancer. 3, 6, p. 659-661 3 p.Research output: Contribution to journal › Article › peer-review
Press / Media
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Nested Therapeutics launches with $125m for precision cancer therapies; The Cambridge startup is mapping genetic mutations in 3D to uncover commonalities between seemingly rare causes of the disease.
6/10/22 → 7/10/22
2 items of Media coverage
Press/Media
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A Versant-backed biotech emerges to take on ‘overlooked’ cancer targets
6/10/22
1 item of Media coverage
Press/Media
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Rapid, scalable assessment of SARS-CoV-2 cellular immunity by whole-blood PCR - Nature Biotechnology
Jocelyn Harris, William Marsiglia, Manishkumar Patel, Kai Nie, Seunghee Kim-Schulze, Robert Sebra, Florian Krammer,, Jordi Ochando, Sacha Gnjatic, Ivan Marazzi,, Ernesto Guccione, Arvin Dar, Megan Schwarz & Denis Torre
6/07/22
1 item of Media coverage
Press/Media
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The Mark Foundation for cancer research announces 2021 ASPIRE awards
Benjamin Greenbaum, Jun Wang, Ernesto Guccione & Arvin Dar
16/12/21
1 item of Media coverage
Press/Media
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Follow the Money: Cloud R&D, Generative Biology, Robotics
Amaia Lujambio, Ernesto Guccione, Arvin Dar & Amaya Lujambio Goizueta,
2/12/21
3 items of Media coverage
Press/Media