Research output per year
Research output per year
Personal profile
Biography
Dr. Pallapati Anusha Rani is an Assistant Professor in the Department of Pharmacological Sciences at the Icahn School of Medicine at Mount Sinai. Her research focuses on developing novel therapeutic strategies, including antibodies and small molecules, for chronic diseases such as osteoporosis, obesity, Huntington’s disease, and Alzheimer’s disease. Dr. Pallapati has extensive expertise in therapeutic antibody development, naïve immune library generation, protein misfolding and characterization, and RNA aptamer technology. She specializes in bioanalytical method development, IND-enabling preclinical studies, and chemistry, manufacturing, and controls (CMC) activities under Good Laboratory Practice (GLP) conditions. With a strong background in cell biology, molecular biology, and immunology, she has led advancements in cell-based potency assays, immunoassays, and biologics development. Certified in both GLP and Good Clinical Practice (GCP), Dr. Pallapati is committed to maintaining high scientific and regulatory standards in her research. In addition to her scientific contributions, she serves as a reviewer and editor for several prestigious journals, contributing to the advancement of biomedical research.
Headline
ASSISTANT PROFESSOR | Pharmacological Sciences
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Collaborations and top research areas from the last five years
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Gene–dose-dependent reduction of Fshr expression improves spatial memory deficits in Alzheimer’s mice
Korkmaz, F., Sims, S., Sen, F., Sultana, F., Laurencin, V., Cullen, L., Pallapati, A., Liu, A., Chen, R., Rojekar, S., Pevnev, G., Cheliadinova, U., Vasilyeva, D., Burganova, G., Macdonald, A., Saxena, M., Goosens, K., Rosen, C. J., Barak, O. & Lizneva, D. & 6 others, , May 2025, In: Molecular Psychiatry. 30, 5, p. 2119-2126 8 p., 6577.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Targeting FSH for osteoporosis, obesity, and Alzheimer's disease
Korkmaz, F., Gimenez-Roig, J., Sultana, F., Laurencin, V., Sen, F., Cullen, L., Sims, S., Pallapati, A., Rojekar, S., Burganova, G., Pevnev, G., Cheliadinova, U., Vasilyeva, D., Moldavski, O., Frolinger, T., Gumerova, A., Barak, O., Ryu, V., Lizneva, D. & Ye, K. & 5 others, , 2025, (Accepted/In press) In: Trends in Molecular Medicine.Research output: Contribution to journal › Review article › peer-review
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FSH, bone, belly and brain
Kim, S. M., Sultana, F., Sims, S., Gimenez-Roig, J., Laurencin, V., Pallapati, A., Rojekar, S., Frolinger, T., Zhou, W., Gumerova, A., Macdonald, A., Ryu, V., Lizneva, D., Korkmaz, F., Yuen, T. & Zaidi, M., Jul 2024, In: Journal of Endocrinology. 262, 1, e230377.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
Neuroendocrinology of bone
Kim, S. M., Sultana, F., Korkmaz, F., Rojekar, S., Pallapati, A., Ryu, V., Lizneva, D., Yuen, T., Rosen, C. J. & Zaidi, M., Dec 2024, In: Pituitary. 27, 6, p. 761-777 17 p.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
Bone circuitry and interorgan skeletal crosstalk
Zaidi, M., Kim, S. M., Mathew, M., Korkmaz, F., Sultana, F., Miyashita, S., Gumerova, A. A., Frolinger, T., Moldavski, O., Barak, O., Pallapati, A., Rojekar, S., Caminis, J., Ginzburg, Y., Ryu, V., Davies, T. F., Lizneva, D., Rosen, C. J. & Yuen, T., 19 Jan 2023, In: eLife. 12Research output: Contribution to journal › Article › peer-review
Open Access31 Scopus citations
Press/Media
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Studies from Icahn School of Medicine at Mount Sinai Update Current Data on Memory Disorders (Gene-dose-dependent Reduction of fshr Expression Improves Spatial Memory Deficits In Alzheimer's Mice)
Lizneva, D., Yuen, T., Zaidi, M., Vitaly, R., Rojekar, S., Pallapati, A. R., Frolinger, T., Sultana, F., Gumerova, A. & Goosens, K.
10/12/24
1 item of Media coverage
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Recent Findings from Icahn School of Medicine at Mount Sinai Provides New Insights into Peptide Hormones (Neuroendocrinology of Bone)
Lizneva, D., Yuen, T., Zaidi, M., Vitaly, R., Rojekar, S., Pallapati, A. R., Sultana, F. & Kim, S.-M.
23/08/24
1 item of Media coverage
Press/Media
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Icahn School of Medicine at Mount Sinai Researchers Describe Recent Advances in Antibodies (Development and biophysical characterization of a humanized FSH-blocking monoclonal antibody therapeutic formulated at an ultra-high concentration)
Lizneva, D., Yuen, T., Zaidi, M., Rojekar, S., Sultana, F., Kim, S.-M. & Pallapati, A. R.
25/07/23
1 item of Media coverage
Press/Media
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Findings from Icahn School of Medicine at Mount Sinai Provides New Data on Hormones (Optimizing a Therapeutic Humanized Follicle-stimulating Hormone-blocking Antibody Formulation By Protein Thermal Shift Assay)
Robinson, C., Lizneva, D., Yuen, T., Zaidi, M., Vitaly, R., Rojekar, S., Sultana, F., Kim, S.-M. & Pallapati, A. R.
16/02/23
1 item of Media coverage
Press/Media