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ASSISTANT PROFESSOR | Pharmacological Sciences
Research interests
Dr. Anisa Gumerova earned her medical degree (MD) from Kazan Medical University in Russia, followed by a PhD and DSc in histology, cytology, and embryology. In Russia, she served as co–principal investigator on several projects devoted to hepatic progenitor cells. As deputy director at the Institute of Fundamental Medicine and Biology of Kazan Federal University, she gained considerable administrative experience. In 2019 Dr. Gumerova joined the Mount Sinai Bone Program under the leadership of Mone Zaidi, MD, PhD, as an associate researcher. Dr. Gumerova’s research focuses on morphological alterations, gene expression, and protein synthesis in various tissues, with a particular emphasis on adipose tissues and bones, under the influence of pituitary hormones such as FSH, luteinizing hormone, thyroid stimulating hormone, and oxytocin. Dr. Gumerova contributes substantially to numerous publications in renowned journals such as Nature, PNAS, and eLife. Dr. Gumerova has introduced innovative methods into the laboratory, including RNA scope in situ hybridization, in vitro and in vivo labeling, and 3D-culture spheroid model. Additionally, she has established an original protocol for isolating single cells from mouse adrenal glands.
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Collaborations and top research areas from the last five years
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Fshr gene depletion prevents recognition memory loss, fat accrual and bone loss in Alzheimer’s mice
Cheliadinova, U., Sims, S., Korkmaz, F., Vasilyeva, D., Laurencin, V., Gimenez-Roig, J., Pevnev, G., Burganova, G., Tumoglu, Z., Parte, S., Sultana, F., Pallapati, A. R., Rojekar, S., Macdonald, A., Hutchison, S., Soussan, A., Liu, A., Wei, Y., Moldavski, O. & Gumerova, A. & 9 others, , May 2026, In: Molecular Psychiatry. 31, 5, p. 2645-2651 7 p.Research output: Contribution to journal › Article › peer-review
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Efficacy and safety of a therapeutic humanized FSH-blocking antibody in obesity and Alzheimer's disease models
Pallapati, A. R., Korkmaz, F., Rojekar, S., Sims, S., Misra, A., Gimenez-Roig, J., Gangadhar, A., Laurencin, V., Gumerova, A., Cheliadinova, U., Sultana, F., Vasilyeva, D., Cullen, L., Schuermann, J., Munitz, J., Kannangara, H., Parte, S., Pevnev, G., Burganova, G. & Tumoglu, Z. & 31 others, , 2025, In: Journal of Clinical Investigation. 135, 17, e182702.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Gene–dose-dependent reduction of Fshr expression improves spatial memory deficits in Alzheimer’s mice
Korkmaz, F., Sims, S., Sen, F., Sultana, F., Laurencin, V., Cullen, L., Pallapati, A., Liu, A., Chen, R., Rojekar, S., Pevnev, G., Cheliadinova, U., Vasilyeva, D., Burganova, G., Macdonald, A., Saxena, M., Goosens, K., Rosen, C. J., Barak, O. & Lizneva, D. & 6 others, , May 2025, In: Molecular Psychiatry. 30, 5, p. 2119-2126 8 p., 6577.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Targeting FSH for osteoporosis, obesity, and Alzheimer’s disease
Korkmaz, F., Gimenez-Roig, J., Sultana, F., Laurencin, V., Sen, F., Cullen, L., Sims, S., Pallapati, A., Rojekar, S., Burganova, G., Pevnev, G., Cheliadinova, U., Vasilyeva, D., Moldavski, O., Frolinger, T., Gumerova, A., Barak, O., Ryu, V., Lizneva, D. & Ye, K. & 5 others, , Nov 2025, In: Trends in Molecular Medicine. 31, 11, p. 1021-1031 11 p.Research output: Contribution to journal › Review article › peer-review
Open Access3 Scopus citations -
An atlas of brain-bone sympathetic neural circuits in mice
Ryu, V., Gumerova, A. A., Witztum, R., Korkmaz, F., Cullen, L., Kannangara, H., Moldavski, O., Barak, O., Lizneva, D., Goosens, K. A., Stanley, S., Kim, S. M., Yuen, T. & Zaidi, M., 4 Jul 2024, In: eLife. 13Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations
Press/Media
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Study Data from Icahn School of Medicine at Mount Sinai Update Knowledge of Posterior Pituitary Hormones [Sex-specific single transcript level atlas of vasopressin and its receptor (AVPR1a) in the mouse brain]
Goosens, K., Zhou, W., Kim, S.-M., Yuen, T., Zaidi, M., Frolinger, T., Sultana, F., Vitaly, R. & Gumerova, A.
30/03/26
1 item of Media coverage
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Researchers at Icahn School of Medicine at Mount Sinai Target Pituitary Hormone Receptors (Single transcript level atlas of oxytocin and the oxytocin receptor in the mouse brain)
Goosens, K., Lizneva, D., Frolinger, T., Sultana, F., Vitaly, R., Gumerova, A. & Moldavski, O.
10/03/26
1 item of Media coverage
Press/Media
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Sex-Specific Brain Atlas Of GLP-1 Reveals Why Weight-Loss Drugs May Work Differently In Females And Males
Yuen, T., Zaidi, M., Vitaly, R. & Gumerova, A.
10/03/26
67 items of Media coverage
Press/Media
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Studies from Icahn School of Medicine at Mount Sinai Update Current Data on Memory Disorders (Gene-dose-dependent Reduction of fshr Expression Improves Spatial Memory Deficits In Alzheimer's Mice)
Lizneva, D., Yuen, T., Zaidi, M., Vitaly, R., Rojekar, S., Pallapati, A. R., Frolinger, T., Sultana, F., Gumerova, A. & Goosens, K.
10/12/24
1 item of Media coverage
Press/Media