Research output per year
Research output per year
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PROFESSOR | Pharmacological Sciences PROFESSOR | Oncological Sciences
Biography
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Dive into the research topics where Aneel Aggarwal is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Signal-induced enhancer activation requires Ku70 to read topoisomerase1–DNA covalent complexes
Tan, Y., Yao, L., Gamliel, A., Nair, S. J., Taylor, H., Ohgi, K., Aggarwal, A. K. & Rosenfeld, M. G., Feb 2023, In: Nature Structural and Molecular Biology. 30, 2, p. 148-158 11 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Cryo-EM structure of translesion DNA synthesis polymerase ζ with a base pair mismatch
Malik, R., Johnson, R. E., Prakash, L., Prakash, S., Ubarretxena-Belandia, I. & Aggarwal, A. K., Dec 2022, In: Nature Communications. 13, 1, 1050.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Discovery of a dual WDR5 and Ikaros PROTAC degrader as an anti-cancer therapeutic
Li, D., Yu, X., Kottur, J., Gong, W., Zhang, Z., Storey, A. J., Tsai, Y. H., Uryu, H., Shen, Y., Byrum, S. D., Edmondson, R. D., Mackintosh, S. G., Cai, L., Liu, Z., Aggarwal, A. K., Tackett, A. J., Liu, J., Jin, J. & Wang, G. G., 10 Jun 2022, In: Oncogene. 41, 24, p. 3328-3340 13 p.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
High-resolution structures of the SARS-CoV-2 N7-methyltransferase inform therapeutic development
Kottur, J., Rechkoblit, O., Quintana-Feliciano, R., Sciaky, D. & Aggarwal, A. K., Sep 2022, In: Nature Structural and Molecular Biology. 29, 9, p. 850-853 4 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
A selective WDR5 degrader inhibits acute myeloid leukemia in patient-derived mouse models
Yu, X., Li, D., Kottur, J., Shen, Y., Kim, H. S., Park, K. S., Tsai, Y. H., Gong, W., Wang, J., Suzuki, K., Parker, J., Herring, L., Kaniskan, H. Ü., Cai, L., Jain, R., Liu, J., Aggarwal, A. K., Wang, G. G. & Jin, J., 29 Sep 2021, In: Science Translational Medicine. 13, 613, eabj1578.Research output: Contribution to journal › Article › peer-review
38 Scopus citations
Press/Media
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Study Findings from Icahn School of Medicine at Mount Sinai Provide New Insights into COVID-19 (Structures of Sars-cov-2 N7-methyltransferase With Dot1l and Prmt7 Inhibitors Provide a Platform for New Antivirals)
Kris White, Aneel Aggarwal, Olga Rechkoblit, Adolfo Garcia-Sastre & Richard Quintana Feliciano
5/09/23
1 item of Media coverage
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Researchers unravel the crystal structure of a key enzyme of SARS-CoV-2, paving the way for new antivirals
14/09/22
1 item of Media coverage
Press/Media
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Mount Sinai Researchers Unravel the Crystal Structure of a Key Enzyme of SARS-CoV-2, Paving the Way for New Antivirals
10/09/22
1 item of Media coverage
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Researchers produce high-resolution crystal structure of enzyme critical to SARS-CoV-2 survival
9/09/22
1 item of Media coverage
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SARS-CoV-2 Enzyme’s Crystal Structure Paves Way to New Antivirals
9/09/22
1 item of Media coverage
Press/Media