Alison Goate

View Scopus Profile

Alison Goate

DPhil

 https://orcid.org/0000-0002-0576-2472
Calculated based on number of publications stored in Pure and citations from Scopus
1987 …2023

Research activity per year

If you made any changes in Pure these will be visible here soon.
Filter
Article

Search results

  • 2012

    Extracellular tau levels are influenced by variability in tau that is associated with tauopathies

    Karch, C. M., Jeng, A. T. & Goate, A. M., 14 Dec 2012, In: Journal of Biological Chemistry. 287, 51, p. 42751-42762 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    129 Scopus citations

  • Family-based genome-wide association study of frontal theta oscillations identifies potassium channel gene KCNJ6

    Kang, S. J., Rangaswamy, M., Manz, N., Wang, J. C., Wetherill, L., Hinrichs, T., Almasy, L., Brooks, A., Chorlian, D. B., Dick, D., Hesselbrock, V., Kramer, J., Kuperman, S., Nurnberger, J., Rice, J., Schuckit, M., Tischfield, J., Bierut, L. J., Edenberg, H. J., Goate, A., & 2 othersForoud, T. & Porjesz, B., Aug 2012, In: Genes, Brain and Behavior. 11, 6, p. 712-719 8 p.

    Research output: Contribution to journal › Article › peer-review

    47 Scopus citations

  • Genetic variants influencing human aging from late-onset Alzheimer's disease (LOAD) genome-wide association studies (GWAS)

    the Genetic and Environmental Risk for Alzheimer’s Disease (GERAD1) Consortium & the Alzheimer’s Research UK (ARUK) Consortium, 1 Aug 2012, In: Neurobiology of Aging. 33, 8, p. 1849.e5-1849.e18

    Research output: Contribution to journal › Article › peer-review

    40 Scopus citations

  • Genotype patterns at PICALM, CR1, BIN1, CLU, and APOE genes are associated with episodic memory

    Barral, S., Bird, T., Goate, A., Farlow, M. R., Diaz-Arrastia, R., Bennett, D. A., Graff-Radford, N., Boeve, B. F., Sweet, R. A., Stern, Y., Wilson, R. S., Foroud, T., Ott, J. & Mayeux, R., 8 May 2012, In: Neurology. 78, 19, p. 1464-1471 8 p.

    Research output: Contribution to journal › Article › peer-review

    83 Scopus citations

  • Interplay of genetic risk factors (CHRNA 5-CHRNA 3-CHRNB4) and cessation treatments in smoking cessation success

    Chen, L. S., Baker, T. B., Piper, M. E., Breslau, N., Cannon, D. S., Doheny, K. F., Gogarten, S. M., Johnson, E. O., Saccone, N. L., Wang, J. C., Weiss, R. B., Goate, A. M. & Bierut, L. J., 1 Jul 2012, In: American Journal of Psychiatry. 169, 7, p. 735-742 8 p.

    Research output: Contribution to journal › Article › peer-review

    110 Scopus citations

  • In vivo human apolipoprotein E isoform fractional turnover rates in the CNS

    Wildsmith, K. R., Basak, J. M., Patterson, B. W., Pyatkivskyy, Y., Kim, J., Yarasheski, K. E., Wang, J. X., Mawuenyega, K. G., Jiang, H., Parsadanian, M., Yoon, H., Kasten, T., Sigurdson, W. C., Xiong, C., Goate, A., Holtzman, D. M. & Bateman, R. J., 4 Jun 2012, In: PLoS ONE. 7, 6, e38013.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    23 Scopus citations

  • Pathway Analysis of Smoking Quantity in Multiple GWAS Identifies Cholinergic and Sensory Pathways

    Harari, O., Wang, J. C., Bucholz, K., Edenberg, H. J., Heath, A., Martin, N. G., Pergadia, M. L., Montgomery, G., Schrage, A., Bierut, L. J., Madden, P. F. & Goate, A. M., 5 Dec 2012, In: PLoS ONE. 7, 12, e50913.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    11 Scopus citations

  • Pooled-DNA sequencing identifies novel causative variants in PSEN1, GRN and MAPT in a clinical early-onset and familial Alzheimer's disease Ibero-American cohort

    Jin, S. C., Pastor, P., Cooper, B., Cervantes, S., Benitez, B. A., Razquin, C., Goate, A. & Cruchaga, C., 2012, In: Alzheimer's Research and Therapy. 4, 4, 34.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    83 Scopus citations

  • Rare missense variants in CHRNB4 are associated with reduced risk of nicotine dependence

    Haller, G., Druley, T., Vallania, F. L., Mitra, R. D., Li, P., Akk, G., Steinbach, J. H., Breslau, N., Johnson, E., Hatsukami, D., Stitzel, J., Bierut, L. J. & Goate, A. M., Feb 2012, In: Human Molecular Genetics. 21, 3, p. 647-655 9 p., ddr498.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    47 Scopus citations

  • Rare variants in APP, PSEN1 and PSEN2 increase risk for AD in late-onset Alzheimer's disease families

    Cruchaga, C., Chakraverty, S., Mayo, K., Vallania, F. L. M., Mitra, R. D., Faber, K., Williamson, J., Bird, T., Diaz-Arrastia, R., Foroud, T. M., Boeve, B. F., Graff-Radford, N. R., St. Jean, P., Lawson, M., Ehm, M. G., Mayeux, R., Goate, A. M. & for the NIA-LOAD - NCRAD Family Study Consortium, T. NIA-LOAD. . NCRAD. F. S. C., 1 Feb 2012, In: PLoS ONE. 7, 2, e31039.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    188 Scopus citations

  • Smoking and genetic risk variation across populations of European, Asian, and African American ancestry-a meta-analysis of chromosome 15q25

    Chen, L. S., Saccone, N. L., Culverhouse, R. C., Bracci, P. M., Chen, C. H., Dueker, N., Han, Y., Huang, H., Jin, G., Kohno, T., Ma, J. Z., Przybeck, T. R., Sanders, A. R., Smith, J. A., Sung, Y. J., Wenzlaff, A. S., Wu, C., Yoon, D., Chen, Y. T., Cheng, Y. C., & 42 othersCho, Y. S., David, S. P., Duan, J., Eaton, C. B., Furberg, H., Goate, A. M., Gu, D., Hansen, H. M., Hartz, S., Hu, Z., Kim, Y. J., Kittner, S. J., Levinson, D. F., Mosley, T. H., Payne, T. J., Rao, D. C., Rice, J. P., Rice, T. K., Schwantes-An, T. H., Shete, S. S., Shi, J., Spitz, M. R., Sun, Y. V., Tsai, F. J., Wang, J. C., Wrensch, M. R., Xian, H., Gejman, P. V., He, J., Hunt, S. C., Kardia, S. L., Li, M. D., Lin, D., Mitchell, B. D., Park, T., Schwartz, A. G., Shen, H., Wiencke, J. K., Wu, J. Y., Yokota, J., Amos, C. I. & Bierut, L. J., May 2012, In: Genetic Epidemiology. 36, 4, p. 340-351 12 p.

    Research output: Contribution to journal › Article › peer-review

    63 Scopus citations

  • The aggregate effect of dopamine genes on dependence symptoms among cocaine users: Cross-validation of a candidate system scoring approach

    Derringer, J., Krueger, R. F., Dick, D. M., Aliev, F., Grucza, R. A., Saccone, S., Agrawal, A., Edenberg, H. J., Goate, A. M., Hesselbrock, V. M., Kramer, J. R., Lin, P., Neuman, R. J., Nurnberger, J. I., Rice, J. P., Tischfield, J. A. & Bierut, L. J., Jul 2012, In: Behavior Genetics. 42, 4, p. 626-635 10 p.

    Research output: Contribution to journal › Article › peer-review

    14 Scopus citations

  • The role of variation at AβPP, PSEN1, PSEN2, and MAPT in late onset Alzheimer's disease

    Gerrish, A., Russo, G., Richards, A., Moskvina, V., Ivanov, D., Harold, D., Sims, R., Abraham, R., Hollingworth, P., Chapman, J., Hamshere, M., Pahwa, J. S., Dowzell, K., Williams, A., Jones, N., Thomas, C., Stretton, A., Morgan, A. R., Lovestone, S., Powell, J., & 73 othersProitsi, P., Lupton, M. K., Brayne, C., Rubinsztein, D. C., Gill, M., Lawlor, B., Lynch, A., Morgan, K., Brown, K. S., Passmore, P. A., Craig, D., McGuinness, B., Todd, S., Johnston, J. A., Holmes, C., Mann, D., Smith, A. D., Love, S., Kehoe, P. G., Hardy, J., Mead, S., Fox, N., Rossor, M., Collinge, J., Maier, W., Jessen, F., Kölsch, H., Heun, R., Schürmann, B., Bussche, H. V. D., Heuser, I., Kornhuber, J., Wiltfang, J., Dichgans, M., Frölich, L., Hampel, H., Hüll, M., Rujescu, D., Goate, A. M., Kauwe, J. S. K., Cruchaga, C., Nowotny, P., Morris, J. C., Mayo, K., Livingston, G., Bass, N. J., Gurling, H., McQuillin, A., Gwilliam, R., Deloukas, P., Davies, G., Harris, S. E., Starr, J. M., Deary, I. J., Al-Chalabi, A., Shaw, C. E., Tsolaki, M., Singleton, A. B., Guerreiro, R., Mühleisen, T. W., Nöthen, M. M., Moebus, S., Jöckel, K. H., Klopp, N., Wichmann, H. E., Carrasquillo, M. M., Pankratz, V. S., Younkin, S. G., Jones, L., Holmans, P. A., O'Donovan, M. C., Owen, M. J. & Williams, J., 2012, In: Journal of Alzheimer's Disease. 28, 2, p. 377-387 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    53 Scopus citations

  • Use of a predictive model derived from in vivo endophenotype measurements to demonstrate associations with a complex locus, CYP2A6

    Bloom, A. J., Harari, O., Martinez, M., Madden, P. A. F., Martin, N. G., Montgomery, G. W., Rice, J. P., Murphy, S. E., Bierut, L. J. & Goate, A., Jul 2012, In: Human Molecular Genetics. 21, 13, p. 3050-3062 13 p., dds114.

    Research output: Contribution to journal › Article › peer-review

    31 Scopus citations

  • Using genome-wide complex trait analysis to quantify 'missing heritability' in Parkinson's disease

    Keller, M. F., Saad, M., Bras, J., Bettella, F., Nicolaou, N., Simón-Sánchez, J., Mittag, F., Büchel, F., Sharma, M., Gibbs, J. R., Schulte, C., Moskvina, V., Durr, A., Holmans, P., Kilarski, L. L., Guerreiro, R., Hernandez, D. G., Brice, A., Ylikotila, P., Stefánsson, H., & 159 othersMajamaa, K., Morris, H. R., Williams, N., Gasser, T., Heutink, P., Wood, N. W., Hardy, J., Martinez, M., Singleton, A. B., Nalls, M. A., Plagnol, V., Sheerin, U. M., Lesage, S., Sveinbjörnsdóttir, S., Arepalli, S., Barker, R., Ben-Shlomo, Y., Berendse, H. W., Berg, D., Bhatia, K., de Bie, R. M. A., Biffi, A., Bloem, B., Bochdanovits, Z., Bonin, M., Brockmann, K., Brooks, J., Burn, D. J., Charlesworth, G., Chen, H., Chinnery, P. F., Chong, S., Clarke, C. E., Cookson, M. R., Cooper, J. M., Corvol, J. C., Counsell, C., Damier, P., Dartigues, J. F., Deloukas, P., Deuschl, G., Dexter, D. T., van Dijk, K. D., Dillman, A., Durif, F., Dürr, A., Edkins, S., Evans, J. R., Foltynie, T., Gao, J., Gardner, M., Goate, A., Gray, E., Gústafsson, Ó., Harris, C., van Hilten, J. J., Hofman, A., Hollenbeck, A., Holton, J., Hu, M., Huang, X., Huber, H., Hudson, G., Hunt, S. E., Huttenlocher, J., Illig, T., Jónsson, P. V., Lambert, J. C., Langford, C., Lees, A., Lichtner, P., Limousin, P., Lopez, G., Lorenz, D., McNeill, A., Moorby, C., Moore, M., Morrison, K. E., Mudanohwo, E., O'Sullivan, S. S., Pearson, J., Perlmutter, J. S., Pétursson, H., Pollak, P., Post, B., Potter, S. C., Ravina, B., Revesz, T., Riess, O., Rivadeneira, F., Rizzu, P., Ryten, M., Sawcer, S. J., Schapira, A., Scheffer, H., Shaw, K., Shoulson, I., Sidransky, E., Smith, C., Spencer, C. C. A., Steinberg, S., Stockton, J. D., Strange, A., Talbot, K., Tanner, C. M., Tashakkori-Ghanbaria, A., Tison, F., Trabzuni, D., Traynor, B. J., Uitterlinden, A. G., Velseboer, D., Vidailhet, M., Walker, R., van de Warrenburg, B., Wickremaratchi, M., Williams-Gray, C. H., Winder-Rhodes, S., Stefánsson, K., Donnelly, P., Barroso, I., Blackwell, J. M., Bramon, E., Brown, M. A., Casas, J. P., Corvin, A., Duncanson, A., Jankowski, J., Markus, H. S., Mathew, C. G., Palmer, C. N. A., Plomin, R., Rautanen, A., Trembath, R. C., Viswanathan, A. C., Band, G., Bellenguez, C., Freeman, C., Hellenthal, G., Giannoulatou, E., Pirinen, M., Pearson, R., Su, Z., Vukcevic, D., Gwilliam, R., Blackburn, H., Bumpstead, S. J., Dronov, S., Gillman, M., Hammond, N., Jayakumar, A., McCann, O. T., Liddle, J., Ravindrarajah, R., Ricketts, M., Waller, M., Weston, P., Widaa, S., Whittaker, P. & McCarthy, M. I., Nov 2012, In: Human Molecular Genetics. 21, 22, p. 4996-5009 14 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    144 Scopus citations

  • Variants located upstream of CHRNB4 on chromosome 15q25.1 are associated with age at onset of daily smoking and habitual smoking

    Kapoor, M., Wang, J. C., Bertelsen, S., Bucholz, K., Budde, J. P., Hinrichs, A., Agrawal, A., Brooks, A., Chorlian, D., Dick, D., Hesselbrock, V., Foroud, T., Kramer, J., Kuperman, S., Manz, N., Nurnberger, J., Porjesz, B., Rice, J., Tischfield, J., Xuei, X., & 4 othersSchuckit, M., Edenberg, H. J., Bierut, L. J. & Goate, A. M., 16 Mar 2012, In: PLoS ONE. 7, 3, e33513.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    22 Scopus citations
  • 2011

    A 3p26-3p25 genetic linkage finding for DSM-IV major depression in heavy smoking families

    Pergadia, M. L., Glowinski, A. L., Wray, N. R., Agrawal, A., Saccone, S. F., Loukola, A., Broms, U., Korhonen, T., Penninx, B. W. J. H., Grant, J. D., Nelson, E. C., Henders, A. K., Schrage, A. J., Chou, Y. L., Keskitalo-Vuokko, K., Zhu, Q., Gordon, S. D., Vink, J. M., De Geus, E. J. C., MacGregor, S., & 11 othersLiu, J. Z., Willemsen, G., Medland, S. E., Boomsma, D. I., Montgomery, G. W., Rice, J. P., Goate, A. M., Heath, A. C., Kaprio, J., Martin, N. G. & Madden, P. A. F., Aug 2011, In: American Journal of Psychiatry. 168, 8, p. 848-852 5 p.

    Research output: Contribution to journal › Article › peer-review

    34 Scopus citations

  • A genome-wide association study of DSM-IV: Cannabis dependence

    Agrawal, A., Lynskey, M. T., Hinrichs, A., Grucza, R., Saccone, S. F., Krueger, R., Neuman, R., Howells, W., Fisher, S., Fox, L., Cloninger, R., Dick, D. M., Doheny, K. F., Edenberg, H. J., Goate, A. M., Hesselbrock, V., Johnson, E., Kramer, J., Kuperman, S., Nurnberger, J. I., & 6 othersPugh, E., Schuckit, M., Tischfield, J., Rice, J. P., Bucholz, K. K. & Bierut, L. J., Jul 2011, In: Addiction Biology. 16, 3, p. 514-518 5 p.

    Research output: Contribution to journal › Article › peer-review

    51 Scopus citations

  • Alternative processing of γ-secretase substrates in common forms of mild cognitive impairment and alzheimer's disease: Evidence for γ-secretase dysfunction

    Hata, S., Fujishige, S., Araki, Y., Taniguchi, M., Urakami, K., Peskind, E., Akatsu, H., Araseki, M., Yamamoto, K., Martins, R. N., Maeda, M., Nishimura, M., Levey, A., Chung, K. A., Montine, T., Leverenz, J., Fagan, A., Goate, A., Bateman, R., Holtzman, D. M., & 4 othersYamamoto, T., Nakaya, T., Gandy, S. & Suzuki, T., Jun 2011, In: Annals of Neurology. 69, 6, p. 1026-1031 6 p.

    Research output: Contribution to journal › Article › peer-review

    39 Scopus citations

  • Amyloid-beta plaque growth in cognitively normal adults: Longitudinal [ 11C]Pittsburgh compound B data

    Vlassenko, A. G., Mintun, M. A., Xiong, C., Sheline, Y. I., Goate, A. M., Benzinger, T. L. S. & Morris, J. C., Nov 2011, In: Annals of Neurology. 70, 5, p. 857-861 5 p.

    Research output: Contribution to journal › Article › peer-review

    123 Scopus citations

  • A quantitative-trait genome-wide association study of alcoholism risk in the community: Findings and implications

    Heath, A. C., Whitfield, J. B., Martin, N. G., Pergadia, M. L., Goate, A. M., Lind, P. A., McEvoy, B. P., Schrage, A. J., Grant, J. D., Chou, Y. L., Zhu, R., Henders, A. K., Medland, S. E., Gordon, S. D., Nelson, E. C., Agrawal, A., Nyholt, D. R., Bucholz, K. K., Madden, P. A. F. & Montgomery, G. W., 15 Sep 2011, In: Biological Psychiatry. 70, 6, p. 513-518 6 p.

    Research output: Contribution to journal › Article › peer-review

    158 Scopus citations

  • Association and expression analyses with single-nucleotide polymorphisms in TOMM40 in Alzheimer disease

    Cruchaga, C., Nowotny, P., Kauwe, J. S. K., Ridge, P. G., Mayo, K., Bertelsen, S., Hinrichs, A., Fagan, A. M., Holtzman, D. M., Morris, J. C. & Goate, A. M., Aug 2011, In: Archives of Neurology. 68, 8, p. 1013-1019 7 p.

    Research output: Contribution to journal › Article › peer-review

    91 Scopus citations

  • Association of TMEM106B gene polymorphism with age at onset in granulin mutation carriers and plasma granulin protein levels

    Cruchaga, C., Graff, C., Chiang, H. H., Wang, J., Hinrichs, A. L., Spiegel, N., Bertelsen, S., Mayo, K., Norton, J. B., Morris, J. C. & Goate, A., May 2011, In: Archives of Neurology. 68, 5, p. 581-586 6 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    121 Scopus citations

  • Biochemical, neuropathological, and neuroimaging characteristics of early-onset Alzheimer's disease due to a novel PSEN1 mutation

    Ringman, J. M., Gylys, K. H., Medina, L. D., Fox, M., Kepe, V., Flores, D. L., Apostolova, L. G., Barrio, J. R., Small, G., Silverman, D. H., Siu, E., Cederbaum, S., Hecimovic, S., Malnar, M., Chakraverty, S., Goate, A. M., Bird, T. D. & Leverenz, J. B., 10 Jan 2011, In: Neuroscience Letters. 487, 3, p. 287-292 6 p.

    Research output: Contribution to journal › Article › peer-review

    32 Scopus citations

  • CHRM2, Parental Monitoring, and Adolescent Externalizing Behavior: Evidence for Gene-Environment Interaction

    Dick, D. M., Meyers, J. L., Latendresse, S. J., Creemers, H. E., Lansford, J. E., Pettit, G. S., Bates, J. E., Dodge, K. A., Budde, J., Goate, A., Buitelaar, J. K., Ormel, J., Verhulst, F. C. & Huizink, A. C., Apr 2011, In: Psychological Science. 22, 4, p. 481-489 9 p.

    Research output: Contribution to journal › Article › peer-review

    42 Scopus citations

  • Common polymorphisms in FMO1 are associated with nicotine dependence

    Hinrichs, A. L., Murphy, S. E., Wang, J. C., Saccone, S., Saccone, N., Steinbach, J. H., Goate, A., Stevens, V. L. & Bierut, L. J., Jul 2011, In: Pharmacogenetics and Genomics. 21, 7, p. 397-402 6 p.

    Research output: Contribution to journal › Article › peer-review

    16 Scopus citations

  • Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

    Hollingworth, P., Harold, D., Sims, R., Gerrish, A., Lambert, J. C., Carrasquillo, M. M., Abraham, R., Hamshere, M. L., Pahwa, J. S., Moskvina, V., Dowzell, K., Jones, N., Stretton, A., Thomas, C., Richards, A., Ivanov, D., Widdowson, C., Chapman, J., Lovestone, S., Powell, J., & 152 othersProitsi, P., Lupton, M. K., Brayne, C., Rubinsztein, D. C., Gill, M., Lawlor, B., Lynch, A., Brown, K. S., Passmore, P. A., Craig, D., McGuinness, B., Todd, S., Holmes, C., Mann, D., Smith, A. D., Beaumont, H., Warden, D., Wilcock, G., Love, S., Kehoe, P. G., Hooper, N. M., Vardy, E. R. L. C., Hardy, J., Mead, S., Fox, N. C., Rossor, M., Collinge, J., Maier, W., Jessen, F., Rüther, E., Schürmann, B., Heun, R., Kölsch, H., Van Den Bussche, H., Heuser, I., Kornhuber, J., Wiltfang, J., Dichgans, M., Frölich, L., Hampel, H., Gallacher, J., Hüll, M., Rujescu, D., Giegling, I., Goate, A. M., Kauwe, J. S. K., Cruchaga, C., Nowotny, P., Morris, J. C., Mayo, K., Sleegers, K., Bettens, K., Engelborghs, S., De Deyn, P. P., Van Broeckhoven, C., Livingston, G., Bass, N. J., Gurling, H., McQuillin, A., Gwilliam, R., Deloukas, P., Al-Chalabi, A., Shaw, C. E., Tsolaki, M., Singleton, A. B., Guerreiro, R., Mühleisen, T. W., Nöthen, M. M., Moebus, S., Jöckel, K. H., Klopp, N., Wichmann, H. E., Pankratz, V. S., Sando, S. B., Aasly, J. O., Barcikowska, M., Wszolek, Z. K., Dickson, D. W., Graff-Radford, N. R., Petersen, R. C., Van Duijn, C. M., Breteler, M. M. B., Ikram, M. A., Destefano, A. L., Fitzpatrick, A. L., Lopez, O., Launer, L. J., Seshadri, S., Berr, C., Campion, D., Epelbaum, J., Dartigues, J. F., Tzourio, C., Alpérovitch, A., Lathrop, M., Feulner, T. M., Friedrich, P., Riehle, C., Krawczak, M., Schreiber, S., Mayhaus, M., Nicolhaus, S., Wagenpfeil, S., Steinberg, S., Stefansson, H., Stefansson, K., SnÆdal, J., Björnsson, S., Jonsson, P. V., Chouraki, V., Genier-Boley, B., Hiltunen, M., Soininen, H., Combarros, O., Zelenika, D., Delepine, M., Bullido, M. J., Pasquier, F., Mateo, I., Frank-Garcia, A., Porcellini, E., Hanon, O., Coto, E., Alvarez, V., Bosco, P., Siciliano, G., Mancuso, M., Panza, F., Solfrizzi, V., Nacmias, B., Sorbi, S., Bossù, P., Piccardi, P., Arosio, B., Annoni, G., Seripa, D., Pilotto, A., Scarpini, E., Galimberti, D., Brice, A., Hannequin, D., Licastro, F., Jones, L., Holmans, P. A., Jonsson, T., Riemenschneider, M., Morgan, K., Younkin, S. G., Owen, M. J., O'Donovan, M., Amouyel, P. & Williams, J., May 2011, In: Nature Genetics. 43, 5, p. 429-436 8 p.

    Research output: Contribution to journal › Article › peer-review

    1492 Scopus citations

  • Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

    Naj, A. C., Jun, G., Beecham, G. W., Wang, L. S., Vardarajan, B. N., Buros, J., Gallins, P. J., Buxbaum, J. D., Jarvik, G. P., Crane, P. K., Larson, E. B., Bird, T. D., Boeve, B. F., Graff-Radford, N. R., De Jager, P. L., Evans, D., Schneider, J. A., Carrasquillo, M. M., Ertekin-Taner, N., Younkin, S. G., & 135 othersCruchaga, C., Kauwe, J. S. K., Nowotny, P., Kramer, P., Hardy, J., Huentelman, M. J., Myers, A. J., Barmada, M. M., Demirci, F. Y., Baldwin, C. T., Green, R. C., Rogaeva, E., George-Hyslop, P. S., Arnold, S. E., Barber, R., Beach, T., Bigio, E. H., Bowen, J. D., Boxer, A., Burke, J. R., Cairns, N. J., Carlson, C. S., Carney, R. M., Carroll, S. L., Chui, H. C., Clark, D. G., Corneveaux, J., Cotman, C. W., Cummings, J. L., Decarli, C., Dekosky, S. T., Diaz-Arrastia, R., Dick, M., Dickson, D. W., Ellis, W. G., Faber, K. M., Fallon, K. B., Farlow, M. R., Ferris, S., Frosch, M. P., Galasko, D. R., Ganguli, M., Gearing, M., Geschwind, D. H., Ghetti, B., Gilbert, J. R., Gilman, S., Giordani, B., Glass, J. D., Growdon, J. H., Hamilton, R. L., Harrell, L. E., Head, E., Honig, L. S., Hulette, C. M., Hyman, B. T., Jicha, G. A., Jin, L. W., Johnson, N., Karlawish, J., Karydas, A., Kaye, J. A., Kim, R., Koo, E. H., Kowall, N. W., Lah, J. J., Levey, A. I., Lieberman, A. P., Lopez, O. L., MacK, W. J., Marson, D. C., Martiniuk, F., Mash, D. C., Masliah, E., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Parisi, J. E., Perl, D. P., Peskind, E., Petersen, R. C., Poon, W. W., Quinn, J. F., Rajbhandary, R. A., Raskind, M., Reisberg, B., Ringman, J. M., Roberson, E. D., Rosenberg, R. N., Sano, M., Schneider, L. S., Seeley, W., Shelanski, M. L., Slifer, M. A., Smith, C. D., Sonnen, J. A., Spina, S., Stern, R. A., Tanzi, R. E., Trojanowski, J. Q., Troncoso, J. C., Van Deerlin, V. M., Vinters, H. V., Vonsattel, J. P., Weintraub, S., Welsh-Bohmer, K. A., Williamson, J., Woltjer, R. L., Cantwell, L. B., Dombroski, B. A., Beekly, D., Lunetta, K. L., Martin, E. R., Kamboh, M. I., Saykin, A. J., Reiman, E. M., Bennett, D. A., Morris, J. C., Montine, T. J., Goate, A. M., Blacker, D., Tsuang, D. W., Hakonarson, H., Kukull, W. A., Foroud, T. M., Haines, J. L., Mayeux, R., Pericak-Vance, M. A., Farrer, L. A. & Schellenberg, G. D., May 2011, In: Nature Genetics. 43, 5, p. 436-443 8 p.

    Research output: Contribution to journal › Article › peer-review

    1465 Scopus citations

  • Copy number variation accuracy in genome-wide association studies

    Lin, P., Hartz, S. M., Wang, J. C., Krueger, R. F., Foroud, T. M., Edenberg, H. J., Nurnberger, J. I., Brooks, A. I., Tischfield, J. A., Almasy, L., Webb, B. T., Hesselbrock, V. M., Porjesz, B., Goate, A. M., Bierut, L. J. & Rice, J. P., Jul 2011, In: Human Heredity. 71, 3, p. 141-147 7 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    11 Scopus citations

  • Death-Associated Protein Kinase 1 Phosphorylates Pin1 and Inhibits Its Prolyl Isomerase Activity and Cellular Function

    Lee, T. H., Chen, C. H., Suizu, F., Huang, P., Schiene-Fischer, C., Daum, S., Zhang, Y. J., Goate, A., Chen, R. H., Zhou, X. Z. & Lu, K. P., 22 Apr 2011, In: Molecular Cell. 42, 2, p. 147-159 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    53 Scopus citations

  • Differential Susceptibility to Adolescent Externalizing Trajectories: Examining the Interplay Between CHRM2 and Peer Group Antisocial Behavior

    Latendresse, S. J., Bates, J. E., Goodnight, J. A., Lansford, J. E., Budde, J. P., Goate, A., Dodge, K. A., Pettit, G. S. & Dick, D. M., Nov 2011, In: Child Development. 82, 6, p. 1797-1814 18 p.

    Research output: Contribution to journal › Article › peer-review

    43 Scopus citations

  • Elevated cortisol in older adults with generalized anxiety disorder is reduced by treatment: A placebo-controlled evaluation of escitalopram

    Lenze, E. J., Mantella, R. C., Shi, P., Goate, A. M., Nowotny, P., Butters, M. A., Andreescu, C., Thompson, P. A. & Rollman, B. L., May 2011, In: American Journal of Geriatric Psychiatry. 19, 5, p. 482-490 9 p.

    Research output: Contribution to journal › Article › peer-review

    54 Scopus citations

  • Exome-sequencing confirms DNAJC5 mutations as cause of adult neuronal ceroid-lipofuscinosis

    Benitez, B. A., Alvarado, D., Cai, Y., Mayo, K., Chakraverty, S., Norton, J., Morris, J. C., Sands, M. S., Goate, A. & Cruchaga, C., 4 Nov 2011, In: PLoS ONE. 6, 11, e26741.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    85 Scopus citations

  • Fine mapping of genetic variants in BIN1, CLU, CR1 and PICALM for association with cerebrospinal fluid biomarkers for Alzheimer's disease

    Kauwe, J. S. K., Cruchaga, C., Karch, C. M., Sadler, B., Lee, M., Mayo, K., Latu, W., Su'a, M., Fagan, A. M., Holtzman, D. M., Morris, J. C. & Goate, A. M., 2011, In: PLoS ONE. 6, 2, e15918.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    8 Scopus citations

  • FUS immunogold labeling TEM analysis of the neuronal cytoplasmic inclusions of neuronal intermediate filament inclusion disease: A frontotemporal lobar degeneration with FUS proteinopathy

    Page, T., Gitcho, M. A., Mosaheb, S., Carter, D., Chakraverty, S., Perry, R. H., Bigio, E. H., Gearing, M., Ferrer, I., Goate, A. M., Cairns, N. J. & Thorpe, J. R., Nov 2011, In: Journal of Molecular Neuroscience. 45, 3, p. 409-421 13 p.

    Research output: Contribution to journal › Article › peer-review

    19 Scopus citations

  • Genetic and clinical features of progranulin-associated frontotemporal lobar degeneration

    Chen-Plotkin, A. S., Martinez-Lage, M., Sleiman, P. M. A., Hu, W., Greene, R., Wood, E. M. C., Bing, S., Grossman, M., Schellenberg, G. D., Hatanpaa, K. J., Weiner, M. F., White, C. L., Brooks, W. S., Halliday, G. M., Kril, J. J., Gearing, M., Beach, T. G., Graff-Radford, N. R., Dickson, D. W., Rademakers, R., & 35 othersBoeve, B. F., Pickering-Brown, S. M., Snowden, J., Van Swieten, J. C., Heutink, P., Seelaar, H., Murrell, J. R., Ghetti, B., Spina, S., Grafman, J., Kaye, J. A., Woltjer, R. L., Mesulam, M., Bigio, E., Lladó, A., Miller, B. L., Alzualde, A., Moreno, F., Rohrer, J. D., Mackenzie, I. R. A., Feldman, H. H., Hamilton, R. L., Cruts, M., Engelborghs, S., De Deyn, P. P., Van Broeckhoven, C., Bird, T. D., Cairns, N. J., Goate, A., Frosch, M. P., Riederer, P. F., Bogdanovic, N., Lee, V. M. Y., Trojanowski, J. Q. & Van Deerlin, V. M., Apr 2011, In: Archives of Neurology. 68, 4, p. 488-497 10 p.

    Research output: Contribution to journal › Article › peer-review

    88 Scopus citations

  • Genetic association of bipolar disorder with the β3 nicotinic receptor subunit gene

    NIMH Genetics Initiative Bipolar Disorder Consortium, Apr 2011, In: Psychiatric Genetics. 21, 2, p. 77-84 8 p.

    Research output: Contribution to journal › Article › peer-review

    9 Scopus citations

  • Genome-wide association of familial late-onset alzheimer's disease replicates BIN1 and CLU and nominates CUGBP2 in interaction with APOE

    Wijsman, E. M., Pankratz, N. D., Choi, Y., Rothstein, J. H., Faber, K. M., Cheng, R., Lee, J. H., Bird, T. D., Bennett, D. A., Diaz-Arrastia, R., Goate, A. M., Farlow, M., Ghetti, B., Sweet, R. A., Foroud, T. M. & Mayeux, R., Feb 2011, In: PLoS Genetics. 7, 2, e1001308.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    167 Scopus citations

  • Genome-wide association study of theta band event-related oscillations identifies serotonin receptor gene HTR7 influencing risk of alcohol dependence

    Zlojutro, M., Manz, N., Rangaswamy, M., Xuei, X., Flury-Wetherill, L., Koller, D., Bierut, L. J., Goate, A., Hesselbrock, V., Kuperman, S., Nurnberger, J., Rice, J. P., Schuckit, M. A., Foroud, T., Edenberg, H. J., Porjesz, B. & Almasy, L., Jan 2011, In: American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 156, 1, p. 44-58 15 p.

    Research output: Contribution to journal › Article › peer-review

    64 Scopus citations

  • Human apoE isoforms differentially regulate brain amyloid-β peptide clearance

    Castellano, J. M., Kim, J., Stewart, F. R., Jiang, H., DeMattos, R. B., Patterson, B. W., Fagan, A. M., Morris, J. C., Mawuenyega, K. G., Cruchaga, C., Goate, A. M., Bales, K. R., Paul, S. M., Bateman, R. J. & Holtzman, D. M., 29 Jun 2011, In: Science Translational Medicine. 3, 89, 89ra57.

    Research output: Contribution to journal › Article › peer-review

    805 Scopus citations

  • The contribution of common CYP2A6 alleles to variation in nicotine metabolism among European-Americans

    Bloom, J., Hinrichs, A. L., Wang, J. C., Von Weymarn, L. B., Kharasch, E. D., Bierut, L. J., Goate, A. & Murphy, S. E., Jul 2011, In: Pharmacogenetics and Genomics. 21, 7, p. 403-416 14 p.

    Research output: Contribution to journal › Article › peer-review

    69 Scopus citations

  • Uncovering hidden variance: Pair-wise SNP analysis accounts for additional variance in nicotine dependence

    Culverhouse, R. C., Saccone, N. L., Stitzel, J. A., Wang, J. C., Steinbach, J. H., Goate, A. M., Schwantes-An, T. H., Grucza, R. A., Stevens, V. L. & Bierut, L. J., Feb 2011, In: Human Genetics. 129, 2, p. 177-188 12 p.

    Research output: Contribution to journal › Article › peer-review

    3 Scopus citations
  • 2010

    A genome-wide association study of alcohol dependence

    Bierut, L. J., Agrawal, A., Bucholz, K. K., Doheny, K. F., Laurie, C., Pugh, E., Fisher, S., Fox, L., Howells, W., Bertelsen, S., Hinrichs, A. L., Almasy, L., Breslau, N., Culverhouse, R. C., Dick, D. M., Edenberg, H. J., Foroud, T., Grucza, R. A., Hatsukami, D., Hesselbrock, V., & 19 othersJohnson, E. O., Kramer, J., Krueger, R. F., Kuperman, S., Lynskey, M., Mann, K., Neuman, R. J., Nöthen, M. M., Nurnberger, J. I., Porjesz, B., Ridinger, M., Saccone, N. L., Saccone, S. F., Schuckit, M. A., Tischfield, J. A., Wang, J. C., Rietschel, M., Goate, A. M. & Rice, J. P., 16 Mar 2010, In: Proceedings of the National Academy of Sciences of the United States of America. 107, 11, p. 5082-5087 6 p.

    Research output: Contribution to journal › Article › peer-review

    369 Scopus citations

  • A new statistic to evaluate imputation reliability

    Lin, P., Hartz, S. M., Zhang, Z., Saccone, S. F., Wang, J., Tischfield, J. A., Edenberg, H. J., Kramer, J. R., Goate, A. M., Bierut, L. J. & Rice, J. P., 2010, In: PLoS ONE. 5, 3, e9697.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    55 Scopus citations

  • An investigation of candidate regions for association with bipolar disorder

    NIMH Genetics Initiative Bipolar Disorder Consortium, 1 Oct 2010, In: American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 153, 7, p. 1292-1297 6 p.

    Research output: Contribution to journal › Article › peer-review

    4 Scopus citations

  • APOE4 allele disrupts resting state fMRI connectivity in the absence of amyloid plaques or decreased CSF Aβ42

    Sheline, Y. I., Morris, J. C., Snyder, A. Z., Price, J. L., Yan, Z., D'Angelo, G., Liu, C., Dixit, S., Benzinger, T., Fagan, A., Goate, A. & Mintun, M. A., 15 Dec 2010, In: Journal of Neuroscience. 30, 50, p. 17035-17040 6 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    349 Scopus citations

  • APOE predicts amyloid-beta but not tau Alzheimer pathology in cognitively normal aging

    Morris, J. C., Roe, C. M., Xiong, C., Fagan, A. M., Goate, A. M., Holtzman, D. M. & Mintun, M. A., 2010, In: Annals of Neurology. 67, 1, p. 122-131 10 p.

    Research output: Contribution to journal › Article › peer-review

    668 Scopus citations

  • Cholesterol accumulation in Niemann Pick type C (NPC) model cells causes a shift in APP localization to lipid rafts

    Kosicek, M., Malnar, M., Goate, A. & Hecimovic, S., 12 Mar 2010, In: Biochemical and Biophysical Research Communications. 393, 3, p. 404-409 6 p.

    Research output: Contribution to journal › Article › peer-review

    51 Scopus citations

  • Cortical Binding of Pittsburgh Compound B, an Endophenotype for Genetic Studies of Alzheimer's Disease

    Hinrichs, A. L., Mintun, M. A., Head, D., Fagan, A. M., Holtzman, D. M., Morris, J. C. & Goate, A. M., 15 Mar 2010, In: Biological Psychiatry. 67, 6, p. 581-583 3 p.

    Research output: Contribution to journal › Article › peer-review

    24 Scopus citations

  • Evidence for genes on chromosome 2 contributing to alcohol dependence with conduct disorder and suicide attempts

    Dick, D. M., Meyers, J., Aliev, F., Nurnberger, J., Kramer, J., Kuperman, S., Porjesz, B., Tischfield, J., Edenberg, H. J., Foroud, T., Schuckit, M., Goate, A., Hesselbrock, V. & Bierut, L., Sep 2010, In: American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 153, 6, p. 1179-1188 10 p.

    Research output: Contribution to journal › Article › peer-review

    34 Scopus citations