Alison Goate

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Alison Goate

DPhil

 https://orcid.org/0000-0002-0576-2472
Calculated based on number of publications stored in Pure and citations from Scopus
1987 …2024

Research activity per year

Search results

  • 2016

    Phenotypic similarities between late-onset Autosomal dominant and sporadic Alzheimer disease a single-family case-control study

    Day, G. S., Musiek, E. S., Roe, C. M., Norton, J., Goate, A. M., Cruchaga, C., Cairns, N. J. & Morris, J. C., 1 Sep 2016, In: JAMA Neurology. 73, 9, p. 1125-1132 8 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    18 Scopus citations

  • Rare, low frequency and common coding variants in CHRNA5 and their contribution to nicotine dependence in European and African Americans

    Olfson, E., Saccone, N. L., Johnson, E. O., Chen, L. S., Culverhouse, R., Doheny, K., Foltz, S. M., Fox, L., Gogarten, S. M., Hartz, S., Hetrick, K., Laurie, C. C., Marosy, B., Amin, N., Arnett, D., Barr, R. G., Bartz, T. M., Bertelsen, S., Borecki, I. B. & Brown, M. R. & 33 others, Chasman, D. I., Van Duijn, C. M., Feitosa, M. F., Fox, E. R., Franceschini, N., Franco, O. H., Grove, M. L., Guo, X., Hofman, A., Kardia, S. L. R., Morrison, A. C., Musani, S. K., Psaty, B. M., Rao, D. C., Reiner, A. P., Rice, K., Ridker, P. M., Rose, L. M., Schick, U. M., Schwander, K., Uitterlinden, A. G., Vojinovic, D., Wang, J. C., Ware, E. B., Wilson, G., Yao, J., Zhao, W., Breslau, N., Hatsukami, D., Stitzel, J. A., Rice, J., Goate, A. & Bierut, L. J., 1 May 2016, In: Molecular Psychiatry. 21, 5, p. 601-607 7 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    31 Scopus citations

  • Shared genetic contribution to ischemic stroke and Alzheimer's disease

    Traylor, M., Adib-Samii, P., Harold, D., Dichgans, M., Williams, J., Lewis, C. M., Markus, H. S., Fornage, M., Holliday, E. G., Sharma, P., Bis, J. C., Psaty, B. M., Seshadri, S., Nalls, M. A., Devan, W. J., Boncoraglio, G., Malik, R., Mitchell, B. D., Kittner, S. J. & Ikram, M. A. & 188 others, Clarke, R., Rosand, J., Meschia, J. F., Sudlow, C., Rothwell, P. M., Levi, C., Bevan, S., Kilarski, L. L., Walters, M., Thijs, V., Slowik, A., Lindgren, A., De Bakker, P. I. W., Lambert, J. C., Ibrahim-Verbaas, C. A., Naj, A. C., Sims, R., Bellenguez, C., Jun, G., Destefano, A. L., Beecham, G. W., Grenier-Boley, B., Russo, G., Thornton-Wells, T. A., Jones, N., Smith, A. V., Chouraki, V., Thomas, C., Zelenika, D., Vardarajan, B. N., Kamatani, Y., Lin, C. F., Gerrish, A., Schmidt, H., Kunkle, B., Dunstan, M. L., Ruiz, A., Bihoreau, M. T., Choi, S. H., Reitz, C., Pasquier, F., Hollingworth, P., Ramirez, A., Hanon, O., Fitzpatrick, A. L., Buxbaum, J. D., Campion, D., Crane, P. K., Baldwin, C., Becker, T., Gudnason, V., Cruchaga, C., Craig, D., Amin, N., Berr, C., Lopez, O. L., De Jager, P. L., Deramecourt, V., Johnston, J. A., Evans, D., Lovestone, S., Letenneur, L., Morón, F. J., Rubinsztein, D. C., Eiriksdottir, G., Sleegers, K., Goate, A. M., Fiçvet, N., Huentelman, M. J., Gill, M., Brown, K., Kamboh, M. I., Keller, L., Barberger-Gateau, P., McGuinness, B., Larson, E. B., Green, R., Myers, A. J., Dufouil, C., Todd, S., Wallon, D., Love, S., Rogaeva, E., Gallacher, J., St George-Hyslop, P., Clarimon, J., Lleo, A., Bayer, A., Tsuang, D. W., Yu, L., Tsolaki, M., Bossù, P., Spalletta, G., Proitsi, P., Collinge, J., Sorbi, S., Sanchez-Garcia, F., Fox, N. C., Hardy, J., Deniz Naranjo, M. C., Bosco, P., Brayne, C., Galimberti, D., Mancuso, M., Matthews, F., Moebus, S., Mecocci, P., Del Zompo, M., Maier, W., Hampel, H., Pilotto, A., Bullido, M., Panza, F., Caffarra, P., Nacmias, B., Gilbert, J. R., Mayhaus, M., Lannfelt, L., Hakonarson, H., Pichler, S., Carrasquillo, M. M., Ingelsson, M., Beekly, D., Alvarez, V., Zou, F., Valladares, O., Younkin, S. G., Coto, E., Hamilton-Nelson, K. L., Gu, W., Razquin, C., Pastor, P., Mateo, I., Owen, M. J., Faber, K. M., Jonsson, P. V., Combarros, O., O'Donovan, M. C., Cantwell, L. B., Soininen, H., Blacker, D., Mead, S., Mosley, T. H., Bennett, D. A., Harris, T. B., Fratiglioni, L., Holmes, C., De Bruijn, R. F. A. G., Passmore, P., Montine, T. J., Bettens, K., Rotter, J. I., Brice, A., Morgan, K., Foroud, T. M., Kukull, W. A., Hannequin, D., Powell, J. F., Nalls, M. A., Ritchie, K., Lunetta, K. L., Kauwe, J. S. K., Boerwinkle, E., Riemenschneider, M., Boada, M., Hiltunen, M., Martin, E. R., Schmidt, R., Rujescu, D., Wang, L. S., Dartigues, J. F., Mayeux, R., Tzourio, C., Hofman, A., Nöthen, M. M., Graff, C., Jones, L., Haines, J. L., Holmans, P. A., Lathrop, M., Pericak-Vance, M. A., Launer, L. J., Farrer, L. A., Van Duijn, C. M., Van Broeckhoven, C., Moskvina, V., Schellenberg, G. D. & Amouyel, P., 1 May 2016, In: Annals of Neurology. 79, 5, p. 739-747 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    53 Scopus citations

  • SORL1 variants across Alzheimer's disease European American cohorts

    Fernández, M. V., Black, K., Carrell, D., Saef, B., Budde, J., Deming, Y., Howells, B., Del-Aguila, J. L., Ma, S., Bi, C., Norton, J., Chasse, R., Morris, J., Goate, A. & Cruchaga, C., 1 Dec 2016, In: European Journal of Human Genetics. 24, 12, p. 1828-1830 3 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    15 Scopus citations

  • The role of cardiovascular risk factors and stroke in familial Alzheimer disease

    Tosto, G., Bird, T. D., Bennett, D. A., Boeve, B. F., Brickman, A. M., Cruchaga, C., Faber, K., Foroud, T. M., Farlow, M., Goate, A. M., Graff-Radford, N. R., Lantigua, R., Manly, J., Ottman, R., Rosenberg, R., Schaid, D. J., Schupf, N., Stern, Y., Sweet, R. A. & Mayeux, R., 1 Oct 2016, In: JAMA Neurology. 73, 10, p. 1231-1237 7 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    45 Scopus citations

  • Variants in ACPP are associated with cerebrospinal fluid Prostatic Acid Phosphatase levels

    for the Alzheimer's Disease Neuroimaging Initiative, 29 Jun 2016, In: BMC Genomics. 17, 439.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    1 Scopus citations

  • Variants in CCL16 are associated with blood plasma and cerebrospinal fluid CCL16 protein levels

    for the Alzheimer's Disease Neuroimaging Initiative, 29 Jun 2016, In: BMC Genomics. 17, 437.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    1 Scopus citations

  • White matter hyperintensities are a core feature of Alzheimer's disease: Evidence from the dominantly inherited Alzheimer network

    Lee, S., Viqar, F., Zimmerman, M. E., Narkhede, A., Tosto, G., Benzinger, T. L. S., Marcus, D. S., Fagan, A. M., Goate, A., Fox, N. C., Cairns, N. J., Holtzman, D. M., Buckles, V., Ghetti, B., McDade, E., Martins, R. N., Saykin, A. J., Masters, C. L., Ringman, J. M. & Ryan, N. S. & 12 others, Förster, S., Laske, C., Schofield, P. R., Sperling, R. A., Salloway, S., Correia, S., Jack, C., Weiner, M., Bateman, R. J., Morris, J. C., Mayeux, R. & Brickman, A. M., 1 Jun 2016, In: Annals of Neurology. 79, 6, p. 929-939 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    381 Scopus citations
  • 2015

    Age and amyloid effects on human central nervous system amyloid-beta kinetics

    Patterson, B. W., Elbert, D. L., Mawuenyega, K. G., Kasten, T., Ovod, V., Ma, S., Xiong, C., Chott, R., Yarasheski, K., Sigurdson, W., Zhang, L., Goate, A., Benzinger, T., Morris, J. C., Holtzman, D. & Bateman, R. J., 1 Sep 2015, In: Annals of Neurology. 78, 3, p. 439-453 15 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    135 Scopus citations

  • A genetic variant (COMT) coding dopaminergic activity predicts personality traits in healthy elderly

    Kotyuk, E., Duchek, J., Head, D., Szekely, A., Goate, A. M. & Balota, D. A., 1 Aug 2015, In: Personality and Individual Differences. 82, p. 61-66 6 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    11 Scopus citations

  • Alzheimer's disease risk genes and mechanisms of disease pathogenesis

    Karch, C. M. & Goate, A. M., 1 Jan 2015, In: Biological Psychiatry. 77, 1, p. 43-51 9 p.

    Research output: Contribution to journal › Review article › peer-review

    Open Access
    947 Scopus citations

  • A multiancestry study identifies novel genetic associations with CHRNA5 methylation in human brain and risk of nicotine dependence

    Hancock, D. B., Wang, J. C., Gaddis, N. C., Levy, J. L., Saccone, N. L., Stitzel, J. A., Goate, A., Bierut, L. J. & Johnson, E. O., 5 Jun 2015, In: Human Molecular Genetics. 24, 20, p. 5940-5954 15 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    28 Scopus citations

  • Amyotrophic lateral sclerosis onset is influenced by the burden of rare variants in known amyotrophic lateral sclerosis genes

    Cady, J., Allred, P., Bali, T., Pestronk, A., Goate, A., Miller, T. M., Mitra, R. D., Ravits, J., Harms, M. B. & Baloh, R. H., 1 Jan 2015, In: Annals of Neurology. 77, 1, p. 100-113 14 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    166 Scopus citations

  • APOE ε4 genotype predicts memory for everyday activities

    Bailey, H. R., Sargent, J. Q., Flores, S., Nowotny, P., Goate, A. & Zacks, J. M., 2 Nov 2015, In: Aging, Neuropsychology, and Cognition. 22, 6, p. 639-666 28 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    9 Scopus citations

  • Association of long runs of homozygosity with Alzheimer disease among African American individuals

    Ghani, M., Reitz, C., Cheng, R., Vardarajan, B. N., Jun, G., Sato, C., Naj, A., Rajbhandary, R., Wang, L. S., Valladares, O., Lin, C. F., Larson, E. B., Graff-Radford, N. R., Evans, D., De Jager, P. L., Crane, P. K., Buxbaum, J. D., Murrell, J. R., Raj, T. & Ertekin-Taner, N. & 153 others, Logue, M., Baldwin, C. T., Green, R. C., Barnes, L. L., Cantwell, L. B., Fallin, M. D., Go, R. C. P., Griffith, P. A., Obisesan, T. O., Manly, J. J., Lunetta, K. L., Kamboh, M. I., Lopez, O. L., Bennett, D. A., Hendrie, H., Hall, K. S., Goate, A. M., Byrd, G. S., Kukull, W. A., Foroud, T. M., Haines, J. L., Farrer, L. A., Pericak-Vance, M. A., Lee, J. H., Schellenberg, G. D., St. George-Hyslop, P., Mayeux, R., Rogaeva, E., Albert, M. S., Albin, R. L., Apostolova, L. G., Arnold, S. E., Barber, R., Barmada, M. M., Beach, T. G., Beecham, G. W., Beekly, D., Bigio, E. H., Bird, T. D., Blacker, D., Boeve, B. F., Bowen, J. D., Boxer, A., Burke, J. R., Cai, G., Cairns, N. J., Cao, C., Carlson, C. S., Carney, R. M., Carroll, S. L., Chui, H. C., Clark, D. G., Cribbs, D. H., Crocco, E. A., Cruchaga, C., DeCarli, C., DeKosky, S. T., Demirci, F. Y., Dick, M., Faber, K. M., Fallon, K. B., Ferris, S., Frosch, M. P., Galasko, D. R., Ganguli, M., Gearing, M., Geschwind, D. H., Ghetti, B., Gilbert, J. R., Gilman, S., Glass, J. D., Growdon, J. H., Hakonarson, H., Hamilton, R. L., Hamilton-Nelson, K. L., Haroutunian, V., Harrell, L. E., Honig, L. S., Hulette, C. M., Hyman, B. T., Jarvik, G. P., Jicha, G. A., Jin, L. W., Karydas, A., Kauwe, J. S. K., Kaye, J. A., Kim, R., Koo, E. H., Kowall, N. W., Kramer, J. H., Kramer, P., LaFerla, F. M., Lah, J. J., Lang-Walker, R., Leverenz, J. B., Levey, A. I., Li, G., Lieberman, A. P., Lyketsos, C. G., Mack, W. J., Marson, D. C., Martiniuk, F., Mash, D. C., Masliah, E., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Montine, T. J., Morris, J. C., Olichney, J. M., Parisi, J. E., Peskind, E., Petersen, R. C., Pierce, A., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Raskind, M., Reiman, E. M., Reisberg, B., Ringman, J. M., Roberson, E. D., Sano, M., Saykin, A. J., Schneider, J. A., Schneider, L. S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., Stern, R. A., Tanzi, R. E., Trojanowski, J. Q., Troncoso, J. C., Tsuang, D. W., Van Deerlin, V. M., Van Eldik, L. J., Vinters, H. V., Vonsattel, J. P., Weintraub, S., Welsh-Bohmer, K. A., Williamson, J., Woltjer, R. L., Wright, C. B., Younkin, S. G., Yu, C. E. & Yu, L., Nov 2015, In: JAMA Neurology. 72, 11, p. 1313-1323 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    30 Scopus citations

  • Association of substance dependence phenotypes in the COGA sample

    Wetherill, L., Agrawal, A., Kapoor, M., Bertelsen, S., Bierut, L. J., Brooks, A., Dick, D., Hesselbrock, M., Hesselbrock, V., Koller, D. L., Le, N., Nurnberger, J. I., Salvatore, J. E., Schuckit, M., Tischfield, J. A., Wang, J. C., Xuei, X., Edenberg, H. J., Porjesz, B. & Bucholz, K. & 2 others, Goate, A. M. & Foroud, T., 1 May 2015, In: Addiction Biology. 20, 3, p. 617-627 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    41 Scopus citations

  • Associations between Potentially Modifiable Risk Factors and Alzheimer Disease: A Mendelian Randomization Study

    Østergaard, S. D., Mukherjee, S., Sharp, S. J., Proitsi, P., Lotta, L. A., Day, F., Perry, J. R. B., Boehme, K. L., Walter, S., Kauwe, J. S., Gibbons, L. E., Larson, E. B., Powell, J. F., Langenberg, C., Crane, P. K., Wareham, N. J., Scott, R. A., Albert, M. S., Albin, R. L. & Apostolova, L. G. & 281 others, Arnold, S. E., Asthana, S., Atwood, C. S., Baldwin, C. T., Barber, R. C., Barmada, M. M., Barnes, L. L., Beach, T. G., Becker, J. T., Beecham, G. W., Beekly, D., Bigio, E. H., Bird, T. D., Blacker, D., Boeve, B. F., Bowen, J. D., Boxer, A., Burke, J. R., Buxbaum, J. D., Cairns, N. J., Cantwell, L. B., Cao, C., Carlson, C. S., Carlsson, C. M., Carney, R. M., Carrasquillo, M. M., Carroll, S. L., Chui, H. C., Clark, D. G., Corneveaux, J., Cribbs, D. H., Crocco, E. A., Cruchaga, C., De Jager, P. L., DeCarli, C., Demirci, F. Y., Dick, M., Dickson, D. W., Duara, R., Ertekin-Taner, N., Evans, D., Faber, K. M., Fallon, K. B., Farlow, M. R., Farrer, L. A., Ferris, S., Foroud, T. M., Frosch, M. P., Galasko, D. R., Gearing, M., Geschwind, D. H., Ghetti, B., Gilbert, J. R., Glass, J. D., Goate, A. M., Graff-Radford, N. R., Green, R. C., Growdon, J. H., Haines, J. L., Hakonarson, H., Hamilton, R. L., Hamilton-Nelson, K. L., Hardy, J., Harrell, L. E., Head, E., Honig, L. S., Huebinger, R. M., Huentelman, M. J., Hulette, C. M., Hyman, B. T., Jarvik, G. P., Jicha, G. A., Jin, L. W., Jun, G., Kamboh, M. I., Karydas, A., Kaye, J. A., Kim, R., Kowall, N. W., Kramer, J. H., Kukull, W. A., Kunkle, B. W., LaFerla, F. M., Lah, J. J., Leverenz, J. B., Levey, A. I., Li, G., Lieberman, A. P., Lin, C. F., Lopez, O. L., Lunetta, K. L., Lyketsos, C. G., Mack, W. J., Marson, D. C., Martin, E. R., Martiniuk, F., Mash, D. C., Masliah, E., Mayeux, R., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Montine, T. J., Morris, J. C., Murrell, J. R., Myers, A. J., Naj, A. C., Olichney, J. M., Pankratz, V. S., Parisi, J. E., Partch, A., Paulson, H. L., Pericak-Vance, M. A., Perry, W., Peskind, E., Petersen, R. C., Pierce, A., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Raskind, M., Reiman, E. M., Reisberg, B., Reitz, C., Ringman, J. M., Roberson, E. D., Rogaeva, E., Rosen, H. J., Rosenberg, R. N., Sager, M. A., Sano, M., Schellenberg, G. D., Schneider, J. A., Schneider, L. S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., St George-Hyslop, P., Stern, R. A., Tanzi, R. E., Thornton-Wells, T. A., Trojanowski, J. Q., Troncoso, J. C., Tsuang, D. W., Valladares, O., VanDeerlin, V. M., Van Eldik, L. J., Vardarajan, B. N., Vinters, H. V., Vonsattel, J. P., Wang, L. S., Weintraub, S., Welsh-Bohmer, K. A., Williamson, J., Wishnek, S., Woltjer, R. L., Wright, C. B., Younkin, S. G., Yu, C. E., Yu, L., Harold, D., Abraham, R., Hollingworth, P., Sims, R., Gerrish, A., Chapman, J., Russo, G., Hamshere, M., Singh Pahwa, J., Escott-Price, V., Badarinarayan, N., Dowzell, K., Williams, A., Jones, N., Thomas, C., Stretton, A., Morgan, A., Taylor, S., Lovestone, S., Lupton, M. K., Brayne, C., Rubinsztein, D. C., Gill, M., Lawlor, B., Lynch, A., Morgan, K., Brown, K., Passmore, P., Craig, D., McGuinness, B., Todd, S., Johnston, J., Holmes, C., Mann, D., David Smith, A., Love, S., Kehoe, P. G., Mead, S., Fox, N., Rossor, M., Collinge, J., Maier, W., Jessen, F., Heun, R., Schürmann, B., Ramirez, A., Becker, T., Herold, C., Lacour, A., Drichel, D., van den Bussche, H., Heuser, I., Kornhuber, J., Wiltfang, J., Dichgans, M., Frölich, L., Hampel, H., Hüll, M., Rujescu, D., Goate, A., Kauwe, J. S. K., Nowotny, P., Mayo, K., Livingston, G., Bass, N. J., Gurling, H., McQuillin, A., Gwilliam, R., Deloukas, P., Al-Chalabi, A., Shaw, C. E., Singleton, A. B., Guerreiro, R., Mühleisen, T. W., Nöthen, M. M., Moebus, S., Jöckel, K. H., Klopp, N., Wichmann, H. E., Shane Pankratz, V., Holmans, P., Donovan, M. O., Owen, M. J., Williams, J., Forouhi, N. G., Kerrison, N. D., Sims, M., Lucarelli, D. M. E., Barroso, I., McCarthy, M. I., Arriola, L., Balkau, B., Barricarte, A., Boeing, H., Franks, P. W., Gonzalez, C., Grioni, S., Kaaks, R., Key, T. J., Navarro, C., Nilsson, P. M., Overvad, K., Palli, D., Panico, S., Ramón Quirós, J., Rolandsson, O., Sacerdote, C., Sánchez, M. J., Slimani, N., Tjonneland, A., Tumino, R., van der Daphne, A. L., van der Schouw, Y. T. & Riboli, E., 1 Jun 2015, In: PLoS Medicine. 12, 6, e1001841.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    147 Scopus citations

  • Cerebral amyloidosis associated with cognitive decline in autosomal dominant Alzheimer disease

    Wang, F., Gordon, B. A., Ryman, D. C., Ma, S., Xiong, C., Hassenstab, J., Goate, A., Fagan, A. M., Cairns, N. J., Marcus, D. S., McDade, E., Ringman, J. M., Graff-Radford, N. R., Ghetti, B., Farlow, M. R., Sperling, R., Salloway, S., Schofield, P. R., Masters, C. L. & Martins, R. N. & 8 others, Rossor, M. N., Jucker, M., Danek, A., Förster, S., Lane, C. A. S., Morris, J. C., Benzinger, T. L. S. & Bateman, R. J., 1 Sep 2015, In: Neurology. 85, 9, p. 790-798 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    24 Scopus citations

  • Common polygenic variation enhances risk prediction for Alzheimer's disease

    Escott-Price, V., Sims, R., Bannister, C., Harold, D., Vronskaya, M., Majounie, E., Badarinarayan, N., Morgan, K., Passmore, P., Holmes, C., Powell, J., Brayne, C., Gill, M., Mead, S., Goate, A., Cruchaga, C., Lambert, J. C., Van Duijn, C., Maier, W. & Ramirez, A. & 7 others, Holmans, P., Jones, L., Hardy, J., Seshadri, S., Schellenberg, G. D., Amouyel, P. & Williams, J., 1 Dec 2015, In: Brain. 138, 12, p. 3673-3684 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    289 Scopus citations

  • Convergent genetic and expression data implicate immunity in Alzheimer's disease

    International Genomics of Alzheimer's Disease Consortium (IGAP), 1 Jun 2015, In: Alzheimer's and Dementia. 11, 6, p. 658-671 14 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    155 Scopus citations

  • Cruchaga & Goate reply

    Cruchaga, C. & Goate, A. M., 2 Apr 2015, In: Nature. 520, 7545, p. E10

    Research output: Contribution to journal › Article › peer-review

    Open Access
    2 Scopus citations

  • Cruchaga & Goate reply

    Cruchaga, C. & Goate, A. M., 2 Apr 2015, In: Nature. 520, 7545, p. E5-E6

    Research output: Contribution to journal › Article › peer-review

    7 Scopus citations

  • Early behavioural changes in familial Alzheimer's disease in the Dominantly Inherited Alzheimer Network

    Ringman, J. M., Liang, L. J., Zhou, Y., Vangala, S., Teng, E., Kremen, S., Wharton, D., Goate, A., Marcus, D. S., Farlow, M., Ghetti, B., McDade, E., Masters, C. L., Mayeux, R. P., Rossor, M., Salloway, S., Schofield, P. R., Cummings, J. L., Buckles, V. & Bateman, R. & 1 others, Morris, J. C., 1 Apr 2015, In: Brain. 138, 4, p. 1036-1045 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    66 Scopus citations

  • Erratum: Early behavioural changes in familial Alzheimers disease in the Dominantly Inherited Alzheimer Network (Brain (2015) 138 (103645) (10.1093/brain/awv004))

    Ringman, J. M., Liang, L. J., Zhou, Y., Vangala, S., Teng, E., Kremen, S., Wharton, D., Goate, A., Marcus, D. S., Farlow, M., Ghetti, B., McDade, E., Masters, C. L., Mayeux, R. P., Rossor, M., Salloway, S., Schofield, P. R., Cummings, J. L., Buckles, V. & Bateman, R. & 1 others, Morris, J. C., 1 Dec 2015, In: Brain. 138, 12, p. e401

    Research output: Contribution to journal › Comment/debate

    Open Access

  • Genes associated with alcohol outcomes show enrichment of effects with broad externalizing and impulsivity phenotypes in an independent sample

    COGA Investigators, 1 Jan 2015, In: Journal of Studies on Alcohol and Drugs. 76, 1, p. 38-46 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    13 Scopus citations

  • Genetically predicted body mass index and Alzheimer's disease-related phenotypes in three large samples: Mendelian randomization analyses

    Adult Changes in Thought Study Investigators, Religious Orders Study/Memory and Aging Project Investigators & Alzheimer's Disease Genetics Consortium, 1 Dec 2015, In: Alzheimer's and Dementia. 11, 12, p. 1439-1451 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    42 Scopus citations

  • Genetic variants associated with susceptibility to psychosis in late-onset Alzheimer's disease families

    NIA-LOAD/NCRAD Family Study Group, Nov 2015, In: Neurobiology of Aging. 36, 11, p. 3116.e9-3116.e16

    Research output: Contribution to journal › Article › peer-review

    Open Access
    15 Scopus citations

  • Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption

    Cornelis, M. C., Byrne, E. M., Esko, T., Nalls, M. A., Ganna, A., Paynter, N., Monda, K. L., Amin, N., Fischer, K., Renstrom, F., Ngwa, J. S., Huikari, V., Cavadino, A., Nolte, I. M., Teumer, A., Yu, K., Marques-Vidal, P., Rawal, R., Manichaikul, A. & Wojczynski, M. K. & 282 others, Vink, J. M., Zhao, J. H., Burlutsky, G., Lahti, J., Mikkilä, V., Lemaitre, R. N., Eriksson, J., Musani, S. K., Tanaka, T., Geller, F., Luan, J., Hui, J., Mägi, R., Dimitriou, M., Garcia, M. E., Ho, W. K., Wright, M. J., Rose, L. M., Magnusson, P. K. E., Pedersen, N. L., Couper, D., Oostra, B. A., Hofman, A., Ikram, M. A., Tiemeier, H. W., Uitterlinden, A. G., van Rooij, F. J. A., Barroso, I., Johansson, I., Xue, L., Kaakinen, M., Milani, L., Power, C., Snieder, H., Stolk, R. P., Baumeister, S. E., Biffar, R., Gu, F., Bastardot, F., Kutalik, Z., Jacobs, D. R., Forouhi, N. G., Mihailov, E., Lind, L., Lindgren, C., Michaëlsson, K., Morris, A., Jensen, M., Khaw, K. T., Luben, R. N., Wang, J. J., Männistö, S., Perälä, M. M., Kähönen, M., Lehtimäki, T., Viikari, J., Mozaffarian, D., Mukamal, K., Psaty, B. M., Döring, A., Heath, A. C., Montgomery, G. W., Dahmen, N., Carithers, T., Tucker, K. L., Ferrucci, L., Boyd, H. A., Melbye, M., Treur, J. L., Mellström, D., Hottenga, J. J., Prokopenko, I., Tönjes, A., Deloukas, P., Kanoni, S., Lorentzon, M., Houston, D. K., Liu, Y., Danesh, J., Rasheed, A., Mason, M. A., Zonderman, A. B., Franke, L., Kristal, B. S., Karjalainen, J., Reed, D. R., Westra, H. J., Evans, M. K., Saleheen, D., Harris, T. B., Dedoussis, G., Curhan, G., Stumvoll, M., Beilby, J., Pasquale, L. R., Feenstra, B., Bandinelli, S., Ordovas, J. M., Chan, A. T., Peters, U., Ohlsson, C., Gieger, C., Martin, N. G., Waldenberger, M., Siscovick, D. S., Raitakari, O., Eriksson, J. G., Mitchell, P., Hunter, D. J., Kraft, P., Rimm, E. B., Boomsma, D. I., Borecki, I. B., Loos, R. J. F., Wareham, N. J., Vollenweider, P., Caporaso, N., Grabe, H. J., Neuhouser, M. L., Wolffenbuttel, B. H. R., Hu, F. B., Hyppönen, E., Järvelin, M. R., Cupples, L. A., Franks, P. W., Ridker, P. M., van Duijn, C. M., Heiss, G., Metspalu, A., North, K. E., Ingelsson, E., Nettleton, J. A., van Dam, R. M., Chasman, D. I., Nalls, M. A., Plagnol, V., Hernandez, D. G., Sharma, M., Sheerin, U. M., Saad, M., Simón-Sánchez, J., Schulte, C., Lesage, S., Sveinbjörnsdóttir, S., Arepalli, S., Barker, R., Ben-Shlomo, Y., Berendse, H. W., Berg, D., Bhatia, K., de Bie, R. M. A., Biffi, A., Bloem, B., Bochdanovits, Z., Bonin, M., Bras, J. M., Brockmann, K., Brooks, J., Burn, D. J., Charlesworth, G., Chen, H., Chinnery, P. F., Chong, S., Clarke, C. E., Cookson, M. R., Cooper, J. M., Corvol, J. C., Counsell, C., Damier, P., Dartigues, J. F., Deloukas, P., Deuschl, G., Dexter, D. T., Dijk, K. D. V., Dillman, A., Durif, F., Dürr, A., Edkins, S., Evans, J. R., Foltynie, T., Dong, J., Gardner, M., Gibbs, J. R., Goate, A., Gray, E., Guerreiro, R., Harris, C., Hilten, J. J. V., Hollenbeck, A., Holton, J., Hu, M., Huang, X., Wurster, I., Mätzler, W., Hudson, G., Hunt, S. E., Huttenlocher, J., Illig, T., Jónsson, P. V., Lambert, J. C., Langford, C., Lees, A., Lichtner, P., Limousin, P., Lopez, G., Lorenz, D., McNeill, A., Moorby, C., Moore, M., Morris, H. R., Morrison, K. E., Mudanohwo, E., O’sullivan, S. S., Pearson, J., Perlmutter, J. S., Pétursson, H., Pollak, P., Post, B., Potter, S., Ravina, B., Revesz, T., Riess, O., Rivadeneira, F., Rizzu, P., Ryten, M., Sawcer, S., Schapira, A., Scheffer, H., Shaw, K., Shoulson, I., Sidransky, E., Smith, C., Spencer, C. C. A., Stefánsson, H., Bettella, F., Stockton, J. D., Strange, A., Talbot, K., Tanner, C. M., Tashakkori-Ghanbaria, A., Tison, F., Trabzuni, D., Traynor, B. J., Velseboer, D., Vidailhet, M., Walker, R., Warrenburg, B. V. D., Wickremaratchi, M., Williams, N., Williams-Gray, C. H., Winder-Rhodes, S., Stefánsson, K., Martinez, M., Wood, N. W., Hardy, J., Heutink, P., Brice, A., Gasser, T., Singleton, A. B., Singleton, A., Cookson, M., Gibbs, J. R., Lila, R., Hernandez, D., Lila, R., Dillman, A., Nalls, M., Zonderman, A., Arepalli, S., Johnson, R., Longo, D., O'brien, R., Traynor, B., Troncoso, J., Brug, M. V. D., Zielke, R., Weale, M., Ryten, M., Ramasamy, A., Lila, R., Trabzuni, D. & Walker, R., 30 May 2015, In: Molecular Psychiatry. 20, 5, p. 647-656 10 p.

    Research output: Contribution to journal › Comment/debate

    Open Access
    206 Scopus citations

  • Integrating mRNA and miRNA weighted gene co-expression networks with eQTLs in the nucleus accumbens of subjects with alcohol dependence

    Mamdani, M., Williamson, V., McMichael, G. O., Blevins, T., Aliev, F., Adkins, A., Hack, L., Bigdeli, T., Van Der Vaart, A. D., Web, B. T., Bacanu, S. A., Kalsi, G., Kendler, K. S., Miles, M. F., Dick, D., Riley, B. P., Dumur, C., Vladimirov, V. I., Hesselbrock, V. & Edenberg, H. J. & 29 others, Nurnberger, J., Foroud, T., Kuperman, S., Kramer, J., Porjesz, B., Bierut, L., Goate, A., Rice, J., Bucholz, K., Schuckit, M., Tischfield, J., Almasy, L., Taylor, R., Dick, D., Bauer, L., Koller, D., O'Connor, S., Wetherill, L., Xuei, X., Chan, G., Kang, S., Manz, N., Rangaswamy, M., Rohrbaugh, J., Wang, J. C., Brooks, A., Aliev, F., Parsian, A. & Reilly, M., 18 Sep 2015, In: PLoS ONE. 10, 9, e0137671.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    65 Scopus citations

  • Lack of an association of BDNF Val66Met polymorphism and plasma BDNF with hippocampal volume and memory

    Kim, A., Fagan, A. M., Goate, A. M., Benzinger, T. L. S., Morris, J. C. & Head, D., 8 Sep 2015, In: Cognitive, Affective and Behavioral Neuroscience. 15, 3, p. 625-643 19 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    36 Scopus citations

  • Linkage analyses in Caribbean Hispanic families identify novel loci associated with familial late-onset Alzheimer's disease

    Barral, S., Cheng, R., Reitz, C., Vardarajan, B., Lee, J., Kunkle, B., Beecham, G., Cantwell, L. S., Pericak-Vance, M. A., Farrer, L. A., Haines, J. L., Goate, A. M., Foroud, T., Boerwinkle, E., Schellenberg, G. D. & Mayeux, R., 1 Dec 2015, In: Alzheimer's and Dementia. 11, 12, p. 1397-1406 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    21 Scopus citations

  • Peroxisome Proliferator-Activated Receptors α and γ are Linked with Alcohol Consumption in Mice and Withdrawal and Dependence in Humans

    Blednov, Y. A., Benavidez, J. M., Black, M., Ferguson, L. B., Schoenhard, G. L., Goate, A. M., Edenberg, H. J., Wetherill, L., Hesselbrock, V., Foroud, T. & Adron Harris, R., 1 Jan 2015, In: Alcoholism: Clinical and Experimental Research. 39, 1, p. 136-145 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    78 Scopus citations

  • Positive selection on loci associated with drug and alcohol dependence

    Sadler, B., Haller, G., Edenberg, H., Tischfield, J., Brooks, A., Kramer, J., Schuckit, M., Nurnberger, J. & Goate, A., 13 Aug 2015, In: PLoS ONE. 10, 8, e0134393.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    5 Scopus citations

  • Quantitative Interaction Proteomics of Neurodegenerative Disease Proteins

    the Genetic and Environmental Risk for Alzheimer’s Disease (GERAD1) Consortium, 19 May 2015, In: Cell Reports. 11, 7, p. 1134-1146 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    78 Scopus citations

  • Rarity of the alzheimer disease-protective APP A673T variant in the United States

    National Institute on Aging-Late-Onset Alzheimer's Disease (NIA-LOAD) Family Study & Alzheimer's Disease Genetics Consortium, 1 Feb 2015, In: JAMA Neurology. 72, 2, p. 209-216 8 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    34 Scopus citations

  • TREM2 is associated with increased risk for Alzheimer's disease in African Americans

    Jin, S. C., Carrasquillo, M. M., Benitez, B. A., Skorupa, T., Carrell, D., Patel, D., Lincoln, S., Krishnan, S., Kachadoorian, M., Reitz, C., Mayeux, R., Wingo, T. S., Lah, J. J., Levey, A. I., Murrell, J., Hendrie, H., Foroud, T., Graff-Radford, N. R., Goate, A. M. & Cruchaga, C. & 1 others, Ertekin-Taner, N., 10 Apr 2015, In: Molecular Neurodegeneration. 10, 1, 19.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    116 Scopus citations
  • 2014

    Age-specific incidence rates for dementia and alzheimer disease in NIA-LOAD/NCRAD and EFIGA families: National Institute on Aging Genetics Initiative for late-onset Alzheimer disease/National Cell Repository for Alzheimer disease (NIA-LOAD/NCRAD) and Estudio Familiar de Influencia Genetica en Alzheimer (EFIGA)

    Vardarajan, B. N., Faber, K. M., Bird, T. D., Bennett, D. A., Rosenberg, R., Boeve, B. F., Graff-Radford, N. R., Goate, A. M., Farlow, M., Sweet, R. A., Lantigua, R., Medrano, M. Z., Ottman, R., Schaid, D. J., Foroud, T. M. & Mayeux, R., Mar 2014, In: JAMA Neurology. 71, 3, p. 315-323 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    48 Scopus citations

  • Alzheimer's disease genetics: From the bench to the clinic

    Karch, C. M., Cruchaga, C. & Goate, A. M., 2 Jul 2014, In: Neuron. 83, 1, p. 11-26 16 p.

    Research output: Contribution to journal › Review article › peer-review

    Open Access
    360 Scopus citations

  • Alzheimer's therapeutics targeting amyloid beta 1-42 oligomers II: Sigma-2/PGRMC1 receptors mediate Abeta 42 oligomer binding and synaptotoxicity

    Izzo, N. J., Xu, J., Zeng, C., Kirk, M. J., Mozzoni, K., Silky, C., Rehak, C., Yurko, R., Look, G., Rishton, G., Safferstein, H., Cruchaga, C., Goate, A., Cahill, M. A., Arancio, O., Mach, R. H., Craven, R., Head, E., LeVine, H. & Spires-Jones, T. L. & 1 others, Catalano, S. M., 12 Nov 2014, In: PLoS ONE. 9, 11, e111899.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    168 Scopus citations

  • An ADH1B variant and peer drinking in progression to adolescent drinking milestones: Evidence of a gene-by-environment interaction

    Olfson, E., Edenberg, H. J., Nurnberger, J., Agrawal, A., Bucholz, K. K., Almasy, L. A., Chorlian, D., Dick, D. M., Hesselbrock, V. M., Kramer, J. R., Kuperman, S., Porjesz, B., Schuckit, M. A., Tischfield, J. A., Wang, J. C., Wetherill, L., Foroud, T. M., Rice, J., Goate, A. & Bierut, L. J., 1 Oct 2014, In: Alcoholism: Clinical and Experimental Research. 38, 10, p. 2541-2549 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    32 Scopus citations

  • A novel PSEN1 mutation (I238M) associated with early-onset Alzheimer's disease in an African-American woman

    Ting, S. K. S., Benzinger, T., Kepe, V., Fagan, A., Coppola, G., Porter, V., Hecimovic, S., Chakraverty, S., Alvarez-Retuerto, A. I., Goate, A. & Ringman, J. M., 2014, In: Journal of Alzheimer's Disease. 40, 2, p. 271-275 5 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    13 Scopus citations

  • A rare mutation in UNC5C predisposes to late-onset Alzheimer's disease and increases neuronal cell death

    Wetzel-Smith, M. K., Hunkapiller, J., Bhangale, T. R., Srinivasan, K., Maloney, J. A., Atwal, J. K., Sa, S. M., Yaylaoglu, M. B., Foreman, O., Ortmann, W., Rathore, N., Hansen, D. V., Tessier-Lavigne, M., Mayeux, R., Pericak-Vance, M., Haines, J., Farrer, L. A., Schellenberg, G. D., Goate, A. & Behrens, T. W. & 3 others, Cruchaga, C., Watts, R. J. & Graham, R. R., 1 Dec 2014, In: Nature Medicine. 20, 12, p. 1452-1457 6 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    110 Scopus citations

  • Association of genes involved in calcium and potassium pathways with opioid dependence

    Wang, J. C., Kapoor, M. & Goate, A. M., 1 Jul 2014, In: Biological Psychiatry. 76, 1, p. 6-7 2 p.

    Research output: Contribution to journal › Comment/debate

    2 Scopus citations

  • Beyond cigarettes per day: A genome-wide association study of the biomarker carbon monoxide

    Bloom, A. J., Hartz, S. M., Baker, T. B., Chen, L. S., Piper, M. E., Fox, L., Martinez, M., Hatsukami, D., Johnson, E. O., Laurie, C. C., Saccone, N. L., Goate, A. & Bierut, L. J., 1 Sep 2014, In: Annals of the American Thoracic Society. 11, 7, p. 1003-1010 8 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    32 Scopus citations

  • Coding variants in TREM2 increase risk for Alzheimer's disease

    Jin, S. C., Benitez, B. A., Karch, C. M., Cooper, B., Skorupa, T., Carrell, D., Norton, J. B., Hsu, S., Harari, O., Cai, Y., Bertelsen, S., Goate, A. M. & Cruchaga, C., 1 Nov 2014, In: Human Molecular Genetics. 23, 21, p. 5838-5846 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    234 Scopus citations

  • DSM-5 cannabis use disorder: A phenotypic and genomic perspective

    Agrawal, A., Lynskey, M. T., Bucholz, K. K., Kapoor, M., Almasy, L., Dick, D. M., Edenberg, H. J., Foroud, T., Goate, A., Hancock, D. B., Hartz, S., Johnson, E. O., Hesselbrock, V., Kramer, J. R., Kuperman, S., Nurnberger, J. I., Schuckit, M. & Bierut, L. J., 1 Jan 2014, In: Drug and Alcohol Dependence. 134, 1, p. 362-369 8 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    36 Scopus citations

  • Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: A genome-wide association study

    Alzheimer Disease Genetics Consortium, 1 Nov 2014, In: JAMA Neurology. 71, 11, p. 1394-1404 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    152 Scopus citations

  • Family-Based Association Analysis of Alcohol Dependence Criteria and Severity

    Wetherill, L., Kapoor, M., Agrawal, A., Bucholz, K., Koller, D., Bertelsen, S. E., Le, N., Wang, J. C., Almasy, L., Hesselbrock, V., Kramer, J., Nurnberger, J. I., Schuckit, M., Tischfield, J. A., Xuei, X., Porjesz, B., Edenberg, H. J., Goate, A. M. & Foroud, T., Feb 2014, In: Alcoholism: Clinical and Experimental Research. 38, 2, p. 354-366 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    22 Scopus citations

  • Functional characterization improves associations between rare non-synonymous variants in CHRNB4 and smoking behavior

    Haller, G., Li, P., Esch, C., Hsu, S., Goate, A. M. & Steinbach, J. H., 7 May 2014, In: PLoS ONE. 9, 5, e96753.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    8 Scopus citations

  • Functional connectivity in autosomal dominant and late-onset Alzheimer disease

    Thomas, J. B., Brier, M. R., Bateman, R. J., Snyder, A. Z., Benzinger, T. L., Xiong, C., Raichle, M., Holtzman, D. M., Sperling, R. A., Mayeux, R., Ghetti, B., Ringman, J. M., Salloway, S., McDade, E., Rossor, M. N., Ourselin, S., Schofield, P. R., Masters, C. L., Martins, R. N. & Weiner, M. W. & 18 others, Thompson, P. M., Fox, N. C., Koeppe, R. A., Jack, C. R., Mathis, C. A., Oliver, A., Blazey, T. M., Moulder, K., Buckles, V., Hornbeck, R., Chhatwal, J., Schultz, A. P., Goate, A. M., Fagan, A. M., Cairns, N. J., Marcus, D. S., Morris, J. C. & Ances, B. M., 1 Sep 2014, In: JAMA Neurology. 71, 9, p. 1111-1122 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    83 Scopus citations