Alison Goate

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Alison Goate

DPhil

 https://orcid.org/0000-0002-0576-2472
Calculated based on number of publications stored in Pure and citations from Scopus
1987 …2023

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Search results

  • 2016

    Chitinase-3-like 1 protein (CHI3L1) locus influences cerebrospinal fluid levels of YKL-40

    Deming, Y., Black, K., Carrell, D., Cai, Y., Del-Aguila, J. L., Fernandez, M. V., Budde, J., Ma, S. M., Saef, B., Howells, B., Bertelsen, S., Huang, K. L., Sutphen, C. L., Tarawneh, R., Fagan, A. M., Holtzman, D. M., Morris, J. C., Goate, A. M., Dougherty, J. D. & Cruchaga, C., 10 Nov 2016, In: BMC Neurology. 16, 1, 217.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    10 Scopus citations

  • Evidence of CNIH3 involvement in opioid dependence

    Nelson, E. C., Agrawal, A., Heath, A. C., Bogdan, R., Sherva, R., Zhang, B., Al-Hasani, R., Bruchas, M. R., Chou, Y. L., Demers, C. H., Carey, C. E., Conley, E. D., Fakira, A. K., Farrer, L. A., Goate, A., Gordon, S., Henders, A. K., Hesselbrock, V., Kapoor, M., Lynskey, M. T., & 19 othersMadden, P. A. F., Moron, J. A., Rice, J. P., Saccone, N. L., Schwab, S. G., Shand, F. L., Todorov, A. A., Wallace, L., Wang, T., Wray, N. R., Zhou, X., Degenhardt, L., Martin, N. G., Hariri, A. R., Kranzler, H. R., Gelernter, J., Bierut, L. J., Clark, D. J. & Montgomery, G. W., 1 May 2016, In: Molecular Psychiatry. 21, 5, p. 608-614 7 p.

    Research output: Contribution to journal › Article › peer-review

    79 Scopus citations

  • Genes for a ‘Wellderly’ Life

    Kauwe, J. S. K. & Goate, A., 1 Aug 2016, In: Trends in Molecular Medicine. 22, 8, p. 637-639 3 p.

    Research output: Contribution to journal › Short survey › peer-review

    3 Scopus citations

  • Genetic studies of plasma analytes identify novel potential biomarkers for several complex traits

    Deming, Y., Xia, J., Cai, Y., Lord, J., Del-Aguila, J. L., Fernandez, M. V., Carrell, D., Black, K., Budde, J., Ma, S., Saef, B., Howells, B., Bertelsen, S., Bailey, M., Ridge, P. G., Holtzman, D., Morris, J. C., Bales, K., Pickering, E. H., Lee, J. M., & 5 othersHeitsch, L., Kauwe, J., Goate, A., Piccio, L. & Cruchaga, C., 4 Jan 2016, In: Scientific Reports. 6, 18092.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    18 Scopus citations

  • Genome-wide association study of prolactin levels in blood plasma and cerebrospinal fluid

    for the Alzheimer's Disease Neuroimaging Initiative, 29 Jun 2016, In: BMC Genomics. 17, 436.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    2 Scopus citations

  • Genome-wide linkage analyses of non-Hispanic white families identify novel loci for familial late-onset Alzheimer's disease

    Kunkle, B. W., Jaworski, J., Barral, S., Vardarajan, B., Beecham, G. W., Martin, E. R., Cantwell, L. S., Partch, A., Bird, T. D., Raskind, W. H., Destefano, A. L., Carney, R. M., Cuccaro, M., Vance, J. M., Farrer, L. A., Goate, A. M., Foroud, T., Mayeux, R. P., Schellenberg, G. D., Haines, J. L., & 1 othersPericak-Vance, M. A., 1 Jan 2016, In: Alzheimer's and Dementia. 12, 1, p. 2-10 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    17 Scopus citations

  • Genome-wide polygenic scores for age at onset of alcohol dependence and association with alcohol-related measures

    Kapoor, M., Chou, Y. L., Edenberg, H. J., Foroud, T., Martin, N. G., Madden, P. A. F., Wang, J. C., Bertelsen, S., Wetherill, L., Brooks, A., Chan, G., Hesselbrock, V., Kuperman, S., Medland, S. E., Montgomery, G., Tischfield, J., Whitfield, J. B., Bierut, L. J., Heath, A. C., Bucholz, K. K., & 2 othersGoate, A. M. & Agrawal, A., 2016, In: Translational Psychiatry. 6, 3, e761.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    2 Scopus citations

  • Global and local ancestry in African-Americans: Implications for Alzheimer's disease risk

    Alzheimer Disease Genetics Consortium, 1 Mar 2016, In: Alzheimer's and Dementia. 12, 3, p. 233-243 11 p.

    Research output: Contribution to journal › Article › peer-review

    33 Scopus citations

  • Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen

    Xu, M., Lee, E. M., Wen, Z., Cheng, Y., Huang, W. K., Qian, X., Tcw, J., Kouznetsova, J., Ogden, S. C., Hammack, C., Jacob, F., Nguyen, H. N., Itkin, M., Hanna, C., Shinn, P., Allen, C., Michael, S. G., Simeonov, A., Huang, W., Christian, K. M., & 8 othersGoate, A., Brennand, K. J., Huang, R., Xia, M., Ming, G. L., Zheng, W., Song, H. & Tang, H., 1 Oct 2016, In: Nature Medicine. 22, 10, p. 1101-1107 7 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    492 Scopus citations

  • Increased nicotine response in iPSC-derived human neurons carrying the CHRNA5 N398 allele

    Oni, E. N., Halikere, A., Li, G., Toro-Ramos, A. J., Swerdel, M. R., Verpeut, J. L., Moore, J. C., Bello, N. T., Bierut, L. J., Goate, A., Tischfield, J. A., Pang, Z. P. & Hart, R. P., 4 Oct 2016, In: Scientific Reports. 6, 34341.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    23 Scopus citations

  • Influence of coding variability in APP-Aβ metabolism genes in sporadic Alzheimer's disease

    Sassi, C., Ridge, P. G., Nalls, M. A., Gibbs, R., Ding, J., Lupton, M. K., Troakes, C., Lunnon, K., Al-Sarraj, S., Brown, K. S., Medway, C., Lord, J., Turton, J., Morgan, K., Powell, J. F., Kauwe, J. S., Cruchaga, C., Bras, J., Goate, A. M., Singleton, A. B., & 18 othersGuerreiro, R., Hardy, J., Passmore, P., Craig, D., Johnston, J., McGuinness, B., Todd, S., Heun, R., Kölsch, H., Kehoe, P. G., Hooper, N. M., Vardy, E. R. L. C., Mann, D. M., Lowe, J., David Smith, A., Wilcock, G., Warden, D. & Holmes, C., Jun 2016, In: PLoS ONE. 11, 6, e0150079.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    24 Scopus citations

  • Integrative network analysis of nineteen brain regions identifies molecular signatures and networks underlying selective regional vulnerability to Alzheimer's disease

    Wang, M., Roussos, P., McKenzie, A., Zhou, X., Kajiwara, Y., Brennand, K. J., De Luca, G. C., Crary, J. F., Casaccia, P., Buxbaum, J. D., Ehrlich, M., Gandy, S., Goate, A., Katsel, P., Schadt, E., Haroutunian, V. & Zhang, B., 1 Nov 2016, In: Genome Medicine. 8, 1, 104.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    156 Scopus citations

  • Loss of VPS13C Function in Autosomal-Recessive Parkinsonism Causes Mitochondrial Dysfunction and Increases PINK1/Parkin-Dependent Mitophagy

    Lesage, S., Drouet, V., Majounie, E., Deramecourt, V., Jacoupy, M., Nicolas, A., Cormier-Dequaire, F., Hassoun, S. M., Pujol, C., Ciura, S., Erpapazoglou, Z., Usenko, T., Maurage, C. A., Sahbatou, M., Liebau, S., Ding, J., Bilgic, B., Emre, M., Erginel-Unaltuna, N., Guven, G., & 176 othersTison, F., Tranchant, C., Vidailhet, M., Corvol, J. C., Krack, P., Leutenegger, A. L., Nalls, M. A., Hernandez, D. G., Heutink, P., Gibbs, J. R., Hardy, J., Wood, N. W., Gasser, T., Durr, A., Deleuze, J. F., Tazir, M., Destée, A., Lohmann, E., Kabashi, E., Singleton, A., Corti, O., Brice, A., Tison, F., Vidailhet, M., Corvol, J. C., Agid, Y., Anheim, M., Bonnet, A. M., Borg, M., Broussolle, E., Damier, P., Destée, A., Dürr, A., Durif, F., Krack, P., Klebe, S., Lohmann, E., Martinez, M., Pollak, P., Rascol, O., Tranchant, C., Vérin, M., Viallet, F., Lesage, S., Majounie, E., Tison, F., Vidailhet, M., Corvol, J. C., Nalls, M. A., Hernandez, D. G., Gibbs, J. R., Dürr, A., Arepalli, S., Barker, R. A., Ben-Shlomo, Y., Berg, D., Bettella, F., Bhatia, K., de Bie, R. M. A., Biffi, A., Bloem, B. R., Bochdanovits, Z., Bonin, M., Bras, J. M., Brockmann, K., Brooks, J., Burn, D. J., Charlesworth, G., Chen, H., Chinnery, P. F., Chong, S., Clarke, C. E., Cookson, M. R., Counsell, C., Damier, P., Dartigues, J. F., Deloukas, P., Deuschl, G., Dexter, D. T., van Dijk, K. D., Dillman, A., Dong, J., Durif, F., Edkins, S., Escott-Price, V., Evans, J. R., Foltynie, T., Gao, J., Gardner, M., Goate, A., Gray, E., Guerreiro, R., Harris, C., van Hilten, J. J., Hofman, A., Hollenbeck, A., Holmans, P., Holton, J., Hu, M., Huang, X., Huber, H., Hudson, G., Hunt, S. E., Huttenlocher, J., Illig, T., Jónsson, P. V., Kilarski, L. L., Jansen, I. E., Lambert, J. C., Langford, C., Lees, A., Lichtner, P., Limousin, P., Lopez, G., Lorenz, D., Lubbe, S., Lungu, C., Martinez, M., Mätzler, W., McNeill, A., Moorby, C., Moore, M., Morrison, K. E., Mudanohwo, E., O’sullivan, S. S., Owen, M. J., Pearson, J., Perlmutter, J. S., Pétursson, H., Plagnol, V., Pollak, P., Post, B., Potter, S., Ravina, B., Revesz, T., Riess, O., Rivadeneira, F., Rizzu, P., Ryten, M., Saad, M., Simón-Sánchez, J., Sawcer, S., Schapira, A., Scheffer, H., Schulte, C., Sharma, M., Shaw, K., Sheerin, U. M., Shoulson, I., Shulman, J., Sidransky, E., Spencer, C. C. A., Stefánsson, H., Stefánsson, K., Stockton, J. D., Strange, A., Talbot, K., Tanner, C. M., Tashakkori-Ghanbaria, A., Trabzuni, D., Traynor, B. J., Uitterlinden, A. G., Velseboer, D., Walker, R., Warrenburg, B. V. D., Wickremaratchi, M., Williams-Gray, C. H., Winder-Rhodes, S., Wurster, I., Williams, N., Morris, H. R., Heutink, P., Wood, N. W., Gasser, T., Singleton, A. B. & Brice, A., 3 Mar 2016, In: American Journal of Human Genetics. 98, 3, p. 500-513 14 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    246 Scopus citations

  • Neurological manifestations of autosomal dominant familial Alzheimer's disease: a comparison of the published literature with the Dominantly Inherited Alzheimer Network observational study (DIAN-OBS)

    Dominantly Inherited Alzheimer Network (DIAN), 1 Dec 2016, In: The Lancet Neurology. 15, 13, p. 1317-1325 9 p.

    Research output: Contribution to journal › Article › peer-review

    70 Scopus citations

  • Phenotypic similarities between late-onset Autosomal dominant and sporadic Alzheimer disease a single-family case-control study

    Day, G. S., Musiek, E. S., Roe, C. M., Norton, J., Goate, A. M., Cruchaga, C., Cairns, N. J. & Morris, J. C., 1 Sep 2016, In: JAMA Neurology. 73, 9, p. 1125-1132 8 p.

    Research output: Contribution to journal › Article › peer-review

    14 Scopus citations

  • Rare, low frequency and common coding variants in CHRNA5 and their contribution to nicotine dependence in European and African Americans

    Olfson, E., Saccone, N. L., Johnson, E. O., Chen, L. S., Culverhouse, R., Doheny, K., Foltz, S. M., Fox, L., Gogarten, S. M., Hartz, S., Hetrick, K., Laurie, C. C., Marosy, B., Amin, N., Arnett, D., Barr, R. G., Bartz, T. M., Bertelsen, S., Borecki, I. B., Brown, M. R., & 33 othersChasman, D. I., Van Duijn, C. M., Feitosa, M. F., Fox, E. R., Franceschini, N., Franco, O. H., Grove, M. L., Guo, X., Hofman, A., Kardia, S. L. R., Morrison, A. C., Musani, S. K., Psaty, B. M., Rao, D. C., Reiner, A. P., Rice, K., Ridker, P. M., Rose, L. M., Schick, U. M., Schwander, K., Uitterlinden, A. G., Vojinovic, D., Wang, J. C., Ware, E. B., Wilson, G., Yao, J., Zhao, W., Breslau, N., Hatsukami, D., Stitzel, J. A., Rice, J., Goate, A. & Bierut, L. J., 1 May 2016, In: Molecular Psychiatry. 21, 5, p. 601-607 7 p.

    Research output: Contribution to journal › Article › peer-review

    26 Scopus citations

  • Shared genetic contribution to ischemic stroke and Alzheimer's disease

    Traylor, M., Adib-Samii, P., Harold, D., Dichgans, M., Williams, J., Lewis, C. M., Markus, H. S., Fornage, M., Holliday, E. G., Sharma, P., Bis, J. C., Psaty, B. M., Seshadri, S., Nalls, M. A., Devan, W. J., Boncoraglio, G., Malik, R., Mitchell, B. D., Kittner, S. J., Ikram, M. A., & 188 othersClarke, R., Rosand, J., Meschia, J. F., Sudlow, C., Rothwell, P. M., Levi, C., Bevan, S., Kilarski, L. L., Walters, M., Thijs, V., Slowik, A., Lindgren, A., De Bakker, P. I. W., Lambert, J. C., Ibrahim-Verbaas, C. A., Naj, A. C., Sims, R., Bellenguez, C., Jun, G., Destefano, A. L., Beecham, G. W., Grenier-Boley, B., Russo, G., Thornton-Wells, T. A., Jones, N., Smith, A. V., Chouraki, V., Thomas, C., Zelenika, D., Vardarajan, B. N., Kamatani, Y., Lin, C. F., Gerrish, A., Schmidt, H., Kunkle, B., Dunstan, M. L., Ruiz, A., Bihoreau, M. T., Choi, S. H., Reitz, C., Pasquier, F., Hollingworth, P., Ramirez, A., Hanon, O., Fitzpatrick, A. L., Buxbaum, J. D., Campion, D., Crane, P. K., Baldwin, C., Becker, T., Gudnason, V., Cruchaga, C., Craig, D., Amin, N., Berr, C., Lopez, O. L., De Jager, P. L., Deramecourt, V., Johnston, J. A., Evans, D., Lovestone, S., Letenneur, L., Morón, F. J., Rubinsztein, D. C., Eiriksdottir, G., Sleegers, K., Goate, A. M., Fiçvet, N., Huentelman, M. J., Gill, M., Brown, K., Kamboh, M. I., Keller, L., Barberger-Gateau, P., McGuinness, B., Larson, E. B., Green, R., Myers, A. J., Dufouil, C., Todd, S., Wallon, D., Love, S., Rogaeva, E., Gallacher, J., St George-Hyslop, P., Clarimon, J., Lleo, A., Bayer, A., Tsuang, D. W., Yu, L., Tsolaki, M., Bossù, P., Spalletta, G., Proitsi, P., Collinge, J., Sorbi, S., Sanchez-Garcia, F., Fox, N. C., Hardy, J., Deniz Naranjo, M. C., Bosco, P., Brayne, C., Galimberti, D., Mancuso, M., Matthews, F., Moebus, S., Mecocci, P., Del Zompo, M., Maier, W., Hampel, H., Pilotto, A., Bullido, M., Panza, F., Caffarra, P., Nacmias, B., Gilbert, J. R., Mayhaus, M., Lannfelt, L., Hakonarson, H., Pichler, S., Carrasquillo, M. M., Ingelsson, M., Beekly, D., Alvarez, V., Zou, F., Valladares, O., Younkin, S. G., Coto, E., Hamilton-Nelson, K. L., Gu, W., Razquin, C., Pastor, P., Mateo, I., Owen, M. J., Faber, K. M., Jonsson, P. V., Combarros, O., O'Donovan, M. C., Cantwell, L. B., Soininen, H., Blacker, D., Mead, S., Mosley, T. H., Bennett, D. A., Harris, T. B., Fratiglioni, L., Holmes, C., De Bruijn, R. F. A. G., Passmore, P., Montine, T. J., Bettens, K., Rotter, J. I., Brice, A., Morgan, K., Foroud, T. M., Kukull, W. A., Hannequin, D., Powell, J. F., Nalls, M. A., Ritchie, K., Lunetta, K. L., Kauwe, J. S. K., Boerwinkle, E., Riemenschneider, M., Boada, M., Hiltunen, M., Martin, E. R., Schmidt, R., Rujescu, D., Wang, L. S., Dartigues, J. F., Mayeux, R., Tzourio, C., Hofman, A., Nöthen, M. M., Graff, C., Jones, L., Haines, J. L., Holmans, P. A., Lathrop, M., Pericak-Vance, M. A., Launer, L. J., Farrer, L. A., Van Duijn, C. M., Van Broeckhoven, C., Moskvina, V., Schellenberg, G. D. & Amouyel, P., 1 May 2016, In: Annals of Neurology. 79, 5, p. 739-747 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    46 Scopus citations

  • SORL1 variants across Alzheimer's disease European American cohorts

    Fernández, M. V., Black, K., Carrell, D., Saef, B., Budde, J., Deming, Y., Howells, B., Del-Aguila, J. L., Ma, S., Bi, C., Norton, J., Chasse, R., Morris, J., Goate, A. & Cruchaga, C., 1 Dec 2016, In: European Journal of Human Genetics. 24, 12, p. 1828-1830 3 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    13 Scopus citations

  • The role of cardiovascular risk factors and stroke in familial Alzheimer disease

    Tosto, G., Bird, T. D., Bennett, D. A., Boeve, B. F., Brickman, A. M., Cruchaga, C., Faber, K., Foroud, T. M., Farlow, M., Goate, A. M., Graff-Radford, N. R., Lantigua, R., Manly, J., Ottman, R., Rosenberg, R., Schaid, D. J., Schupf, N., Stern, Y., Sweet, R. A. & Mayeux, R., 1 Oct 2016, In: JAMA Neurology. 73, 10, p. 1231-1237 7 p.

    Research output: Contribution to journal › Article › peer-review

    38 Scopus citations

  • Variants in ACPP are associated with cerebrospinal fluid Prostatic Acid Phosphatase levels

    for the Alzheimer's Disease Neuroimaging Initiative, 29 Jun 2016, In: BMC Genomics. 17, 439.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    1 Scopus citations

  • Variants in CCL16 are associated with blood plasma and cerebrospinal fluid CCL16 protein levels

    for the Alzheimer's Disease Neuroimaging Initiative, 29 Jun 2016, In: BMC Genomics. 17, 437.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    1 Scopus citations

  • White matter hyperintensities are a core feature of Alzheimer's disease: Evidence from the dominantly inherited Alzheimer network

    Lee, S., Viqar, F., Zimmerman, M. E., Narkhede, A., Tosto, G., Benzinger, T. L. S., Marcus, D. S., Fagan, A. M., Goate, A., Fox, N. C., Cairns, N. J., Holtzman, D. M., Buckles, V., Ghetti, B., McDade, E., Martins, R. N., Saykin, A. J., Masters, C. L., Ringman, J. M., Ryan, N. S., & 12 othersFörster, S., Laske, C., Schofield, P. R., Sperling, R. A., Salloway, S., Correia, S., Jack, C., Weiner, M., Bateman, R. J., Morris, J. C., Mayeux, R. & Brickman, A. M., 1 Jun 2016, In: Annals of Neurology. 79, 6, p. 929-939 11 p.

    Research output: Contribution to journal › Article › peer-review

    293 Scopus citations
  • 2015

    Age and amyloid effects on human central nervous system amyloid-beta kinetics

    Patterson, B. W., Elbert, D. L., Mawuenyega, K. G., Kasten, T., Ovod, V., Ma, S., Xiong, C., Chott, R., Yarasheski, K., Sigurdson, W., Zhang, L., Goate, A., Benzinger, T., Morris, J. C., Holtzman, D. & Bateman, R. J., 1 Sep 2015, In: Annals of Neurology. 78, 3, p. 439-453 15 p.

    Research output: Contribution to journal › Article › peer-review

    99 Scopus citations

  • A genetic variant (COMT) coding dopaminergic activity predicts personality traits in healthy elderly

    Kotyuk, E., Duchek, J., Head, D., Szekely, A., Goate, A. M. & Balota, D. A., 1 Aug 2015, In: Personality and Individual Differences. 82, p. 61-66 6 p.

    Research output: Contribution to journal › Article › peer-review

    9 Scopus citations

  • Alzheimer's disease risk genes and mechanisms of disease pathogenesis

    Karch, C. M. & Goate, A. M., 1 Jan 2015, In: Biological Psychiatry. 77, 1, p. 43-51 9 p.

    Research output: Contribution to journal › Review article › peer-review

    778 Scopus citations

  • A multiancestry study identifies novel genetic associations with CHRNA5 methylation in human brain and risk of nicotine dependence

    Hancock, D. B., Wang, J. C., Gaddis, N. C., Levy, J. L., Saccone, N. L., Stitzel, J. A., Goate, A., Bierut, L. J. & Johnson, E. O., 5 Jun 2015, In: Human Molecular Genetics. 24, 20, p. 5940-5954 15 p.

    Research output: Contribution to journal › Article › peer-review

    23 Scopus citations

  • Amyotrophic lateral sclerosis onset is influenced by the burden of rare variants in known amyotrophic lateral sclerosis genes

    Cady, J., Allred, P., Bali, T., Pestronk, A., Goate, A., Miller, T. M., Mitra, R. D., Ravits, J., Harms, M. B. & Baloh, R. H., 1 Jan 2015, In: Annals of Neurology. 77, 1, p. 100-113 14 p.

    Research output: Contribution to journal › Article › peer-review

    146 Scopus citations

  • APOE ε4 genotype predicts memory for everyday activities

    Bailey, H. R., Sargent, J. Q., Flores, S., Nowotny, P., Goate, A. & Zacks, J. M., 2 Nov 2015, In: Aging, Neuropsychology, and Cognition. 22, 6, p. 639-666 28 p.

    Research output: Contribution to journal › Article › peer-review

    8 Scopus citations

  • Association of long runs of homozygosity with Alzheimer disease among African American individuals

    Ghani, M., Reitz, C., Cheng, R., Vardarajan, B. N., Jun, G., Sato, C., Naj, A., Rajbhandary, R., Wang, L. S., Valladares, O., Lin, C. F., Larson, E. B., Graff-Radford, N. R., Evans, D., De Jager, P. L., Crane, P. K., Buxbaum, J. D., Murrell, J. R., Raj, T., Ertekin-Taner, N., & 153 othersLogue, M., Baldwin, C. T., Green, R. C., Barnes, L. L., Cantwell, L. B., Fallin, M. D., Go, R. C. P., Griffith, P. A., Obisesan, T. O., Manly, J. J., Lunetta, K. L., Kamboh, M. I., Lopez, O. L., Bennett, D. A., Hendrie, H., Hall, K. S., Goate, A. M., Byrd, G. S., Kukull, W. A., Foroud, T. M., Haines, J. L., Farrer, L. A., Pericak-Vance, M. A., Lee, J. H., Schellenberg, G. D., St. George-Hyslop, P., Mayeux, R., Rogaeva, E., Albert, M. S., Albin, R. L., Apostolova, L. G., Arnold, S. E., Barber, R., Barmada, M. M., Beach, T. G., Beecham, G. W., Beekly, D., Bigio, E. H., Bird, T. D., Blacker, D., Boeve, B. F., Bowen, J. D., Boxer, A., Burke, J. R., Cai, G., Cairns, N. J., Cao, C., Carlson, C. S., Carney, R. M., Carroll, S. L., Chui, H. C., Clark, D. G., Cribbs, D. H., Crocco, E. A., Cruchaga, C., DeCarli, C., DeKosky, S. T., Demirci, F. Y., Dick, M., Faber, K. M., Fallon, K. B., Ferris, S., Frosch, M. P., Galasko, D. R., Ganguli, M., Gearing, M., Geschwind, D. H., Ghetti, B., Gilbert, J. R., Gilman, S., Glass, J. D., Growdon, J. H., Hakonarson, H., Hamilton, R. L., Hamilton-Nelson, K. L., Haroutunian, V., Harrell, L. E., Honig, L. S., Hulette, C. M., Hyman, B. T., Jarvik, G. P., Jicha, G. A., Jin, L. W., Karydas, A., Kauwe, J. S. K., Kaye, J. A., Kim, R., Koo, E. H., Kowall, N. W., Kramer, J. H., Kramer, P., LaFerla, F. M., Lah, J. J., Lang-Walker, R., Leverenz, J. B., Levey, A. I., Li, G., Lieberman, A. P., Lyketsos, C. G., Mack, W. J., Marson, D. C., Martiniuk, F., Mash, D. C., Masliah, E., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Montine, T. J., Morris, J. C., Olichney, J. M., Parisi, J. E., Peskind, E., Petersen, R. C., Pierce, A., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Raskind, M., Reiman, E. M., Reisberg, B., Ringman, J. M., Roberson, E. D., Sano, M., Saykin, A. J., Schneider, J. A., Schneider, L. S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., Stern, R. A., Tanzi, R. E., Trojanowski, J. Q., Troncoso, J. C., Tsuang, D. W., Van Deerlin, V. M., Van Eldik, L. J., Vinters, H. V., Vonsattel, J. P., Weintraub, S., Welsh-Bohmer, K. A., Williamson, J., Woltjer, R. L., Wright, C. B., Younkin, S. G., Yu, C. E. & Yu, L., Nov 2015, In: JAMA Neurology. 72, 11, p. 1313-1323 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    30 Scopus citations

  • Association of substance dependence phenotypes in the COGA sample

    Wetherill, L., Agrawal, A., Kapoor, M., Bertelsen, S., Bierut, L. J., Brooks, A., Dick, D., Hesselbrock, M., Hesselbrock, V., Koller, D. L., Le, N., Nurnberger, J. I., Salvatore, J. E., Schuckit, M., Tischfield, J. A., Wang, J. C., Xuei, X., Edenberg, H. J., Porjesz, B., Bucholz, K., & 2 othersGoate, A. M. & Foroud, T., 1 May 2015, In: Addiction Biology. 20, 3, p. 617-627 11 p.

    Research output: Contribution to journal › Article › peer-review

    37 Scopus citations

  • Associations between Potentially Modifiable Risk Factors and Alzheimer Disease: A Mendelian Randomization Study

    Alzheimer’s Disease Genetics Consortium, The GERAD1 Consortium & EPIC-InterAct Consortium, 1 Jun 2015, In: PLoS Medicine. 12, 6, e1001841.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    126 Scopus citations

  • Cerebral amyloidosis associated with cognitive decline in autosomal dominant Alzheimer disease

    Wang, F., Gordon, B. A., Ryman, D. C., Ma, S., Xiong, C., Hassenstab, J., Goate, A., Fagan, A. M., Cairns, N. J., Marcus, D. S., McDade, E., Ringman, J. M., Graff-Radford, N. R., Ghetti, B., Farlow, M. R., Sperling, R., Salloway, S., Schofield, P. R., Masters, C. L., Martins, R. N., & 8 othersRossor, M. N., Jucker, M., Danek, A., Förster, S., Lane, C. A. S., Morris, J. C., Benzinger, T. L. S. & Bateman, R. J., 1 Sep 2015, In: Neurology. 85, 9, p. 790-798 9 p.

    Research output: Contribution to journal › Article › peer-review

    22 Scopus citations

  • Common polygenic variation enhances risk prediction for Alzheimer's disease

    Escott-Price, V., Sims, R., Bannister, C., Harold, D., Vronskaya, M., Majounie, E., Badarinarayan, N., Morgan, K., Passmore, P., Holmes, C., Powell, J., Brayne, C., Gill, M., Mead, S., Goate, A., Cruchaga, C., Lambert, J. C., Van Duijn, C., Maier, W., Ramirez, A., & 7 othersHolmans, P., Jones, L., Hardy, J., Seshadri, S., Schellenberg, G. D., Amouyel, P. & Williams, J., 1 Dec 2015, In: Brain. 138, 12, p. 3673-3684 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    240 Scopus citations

  • Convergent genetic and expression data implicate immunity in Alzheimer's disease

    International Genomics of Alzheimer's Disease Consortium (IGAP), 1 Jun 2015, In: Alzheimer's and Dementia. 11, 6, p. 658-671 14 p.

    Research output: Contribution to journal › Article › peer-review

    142 Scopus citations

  • Cruchaga & Goate reply

    Cruchaga, C. & Goate, A. M., 2 Apr 2015, In: Nature. 520, 7545, p. E5-E6

    Research output: Contribution to journal › Article › peer-review

    7 Scopus citations

  • Cruchaga & Goate reply

    Cruchaga, C. & Goate, A. M., 2 Apr 2015, In: Nature. 520, 7545, p. E10

    Research output: Contribution to journal › Article › peer-review

    2 Scopus citations

  • Early behavioural changes in familial Alzheimer's disease in the Dominantly Inherited Alzheimer Network

    Ringman, J. M., Liang, L. J., Zhou, Y., Vangala, S., Teng, E., Kremen, S., Wharton, D., Goate, A., Marcus, D. S., Farlow, M., Ghetti, B., McDade, E., Masters, C. L., Mayeux, R. P., Rossor, M., Salloway, S., Schofield, P. R., Cummings, J. L., Buckles, V., Bateman, R., & 1 othersMorris, J. C., 1 Apr 2015, In: Brain. 138, 4, p. 1036-1045 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    55 Scopus citations

  • Erratum: Early behavioural changes in familial Alzheimers disease in the Dominantly Inherited Alzheimer Network (Brain (2015) 138 (103645) (10.1093/brain/awv004))

    Ringman, J. M., Liang, L. J., Zhou, Y., Vangala, S., Teng, E., Kremen, S., Wharton, D., Goate, A., Marcus, D. S., Farlow, M., Ghetti, B., McDade, E., Masters, C. L., Mayeux, R. P., Rossor, M., Salloway, S., Schofield, P. R., Cummings, J. L., Buckles, V., Bateman, R., & 1 othersMorris, J. C., 1 Dec 2015, In: Brain. 138, 12, p. e401

    Research output: Contribution to journal › Comment/debate

    Open Access

  • Genes associated with alcohol outcomes show enrichment of effects with broad externalizing and impulsivity phenotypes in an independent sample

    COGA Investigators, 1 Jan 2015, In: Journal of Studies on Alcohol and Drugs. 76, 1, p. 38-46 9 p.

    Research output: Contribution to journal › Article › peer-review

    11 Scopus citations

  • Genetically predicted body mass index and Alzheimer's disease-related phenotypes in three large samples: Mendelian randomization analyses

    Adult Changes in Thought Study Investigators, Religious Orders Study/Memory and Aging Project Investigators & Alzheimer's Disease Genetics Consortium, 1 Dec 2015, In: Alzheimer's and Dementia. 11, 12, p. 1439-1451 13 p.

    Research output: Contribution to journal › Article › peer-review

    39 Scopus citations

  • Genetic variants associated with susceptibility to psychosis in late-onset Alzheimer's disease families

    NIA-LOAD/NCRAD Family Study Group, Nov 2015, In: Neurobiology of Aging. 36, 11, p. 3116.e9-3116.e16

    Research output: Contribution to journal › Article › peer-review

    Open Access
    10 Scopus citations

  • Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption

    Cornelis, M. C., Byrne, E. M., Esko, T., Nalls, M. A., Ganna, A., Paynter, N., Monda, K. L., Amin, N., Fischer, K., Renstrom, F., Ngwa, J. S., Huikari, V., Cavadino, A., Nolte, I. M., Teumer, A., Yu, K., Marques-Vidal, P., Rawal, R., Manichaikul, A., Wojczynski, M. K., & 282 othersVink, J. M., Zhao, J. H., Burlutsky, G., Lahti, J., Mikkilä, V., Lemaitre, R. N., Eriksson, J., Musani, S. K., Tanaka, T., Geller, F., Luan, J., Hui, J., Mägi, R., Dimitriou, M., Garcia, M. E., Ho, W. K., Wright, M. J., Rose, L. M., Magnusson, P. K. E., Pedersen, N. L., Couper, D., Oostra, B. A., Hofman, A., Ikram, M. A., Tiemeier, H. W., Uitterlinden, A. G., van Rooij, F. J. A., Barroso, I., Johansson, I., Xue, L., Kaakinen, M., Milani, L., Power, C., Snieder, H., Stolk, R. P., Baumeister, S. E., Biffar, R., Gu, F., Bastardot, F., Kutalik, Z., Jacobs, D. R., Forouhi, N. G., Mihailov, E., Lind, L., Lindgren, C., Michaëlsson, K., Morris, A., Jensen, M., Khaw, K. T., Luben, R. N., Wang, J. J., Männistö, S., Perälä, M. M., Kähönen, M., Lehtimäki, T., Viikari, J., Mozaffarian, D., Mukamal, K., Psaty, B. M., Döring, A., Heath, A. C., Montgomery, G. W., Dahmen, N., Carithers, T., Tucker, K. L., Ferrucci, L., Boyd, H. A., Melbye, M., Treur, J. L., Mellström, D., Hottenga, J. J., Prokopenko, I., Tönjes, A., Deloukas, P., Kanoni, S., Lorentzon, M., Houston, D. K., Liu, Y., Danesh, J., Rasheed, A., Mason, M. A., Zonderman, A. B., Franke, L., Kristal, B. S., Karjalainen, J., Reed, D. R., Westra, H. J., Evans, M. K., Saleheen, D., Harris, T. B., Dedoussis, G., Curhan, G., Stumvoll, M., Beilby, J., Pasquale, L. R., Feenstra, B., Bandinelli, S., Ordovas, J. M., Chan, A. T., Peters, U., Ohlsson, C., Gieger, C., Martin, N. G., Waldenberger, M., Siscovick, D. S., Raitakari, O., Eriksson, J. G., Mitchell, P., Hunter, D. J., Kraft, P., Rimm, E. B., Boomsma, D. I., Borecki, I. B., Loos, R. J. F., Wareham, N. J., Vollenweider, P., Caporaso, N., Grabe, H. J., Neuhouser, M. L., Wolffenbuttel, B. H. R., Hu, F. B., Hyppönen, E., Järvelin, M. R., Cupples, L. A., Franks, P. W., Ridker, P. M., van Duijn, C. M., Heiss, G., Metspalu, A., North, K. E., Ingelsson, E., Nettleton, J. A., van Dam, R. M., Chasman, D. I., Nalls, M. A., Plagnol, V., Hernandez, D. G., Sharma, M., Sheerin, U. M., Saad, M., Simón-Sánchez, J., Schulte, C., Lesage, S., Sveinbjörnsdóttir, S., Arepalli, S., Barker, R., Ben-Shlomo, Y., Berendse, H. W., Berg, D., Bhatia, K., de Bie, R. M. A., Biffi, A., Bloem, B., Bochdanovits, Z., Bonin, M., Bras, J. M., Brockmann, K., Brooks, J., Burn, D. J., Charlesworth, G., Chen, H., Chinnery, P. F., Chong, S., Clarke, C. E., Cookson, M. R., Cooper, J. M., Corvol, J. C., Counsell, C., Damier, P., Dartigues, J. F., Deloukas, P., Deuschl, G., Dexter, D. T., Dijk, K. D. V., Dillman, A., Durif, F., Dürr, A., Edkins, S., Evans, J. R., Foltynie, T., Dong, J., Gardner, M., Gibbs, J. R., Goate, A., Gray, E., Guerreiro, R., Harris, C., Hilten, J. J. V., Hollenbeck, A., Holton, J., Hu, M., Huang, X., Wurster, I., Mätzler, W., Hudson, G., Hunt, S. E., Huttenlocher, J., Illig, T., Jónsson, P. V., Lambert, J. C., Langford, C., Lees, A., Lichtner, P., Limousin, P., Lopez, G., Lorenz, D., McNeill, A., Moorby, C., Moore, M., Morris, H. R., Morrison, K. E., Mudanohwo, E., O’sullivan, S. S., Pearson, J., Perlmutter, J. S., Pétursson, H., Pollak, P., Post, B., Potter, S., Ravina, B., Revesz, T., Riess, O., Rivadeneira, F., Rizzu, P., Ryten, M., Sawcer, S., Schapira, A., Scheffer, H., Shaw, K., Shoulson, I., Sidransky, E., Smith, C., Spencer, C. C. A., Stefánsson, H., Bettella, F., Stockton, J. D., Strange, A., Talbot, K., Tanner, C. M., Tashakkori-Ghanbaria, A., Tison, F., Trabzuni, D., Traynor, B. J., Velseboer, D., Vidailhet, M., Walker, R., Warrenburg, B. V. D., Wickremaratchi, M., Williams, N., Williams-Gray, C. H., Winder-Rhodes, S., Stefánsson, K., Martinez, M., Wood, N. W., Hardy, J., Heutink, P., Brice, A., Gasser, T., Singleton, A. B., Singleton, A., Cookson, M., Gibbs, J. R., Lila, R., Hernandez, D., Lila, R., Dillman, A., Nalls, M., Zonderman, A., Arepalli, S., Johnson, R., Longo, D., O'brien, R., Traynor, B., Troncoso, J., Brug, M. V. D., Zielke, R., Weale, M., Ryten, M., Ramasamy, A., Lila, R., Trabzuni, D. & Walker, R., 30 May 2015, In: Molecular Psychiatry. 20, 5, p. 647-656 10 p.

    Research output: Contribution to journal › Comment/debate

    Open Access
    171 Scopus citations

  • Integrating mRNA and miRNA weighted gene co-expression networks with eQTLs in the nucleus accumbens of subjects with alcohol dependence

    Mamdani, M., Williamson, V., McMichael, G. O., Blevins, T., Aliev, F., Adkins, A., Hack, L., Bigdeli, T., Van Der Vaart, A. D., Web, B. T., Bacanu, S. A., Kalsi, G., Kendler, K. S., Miles, M. F., Dick, D., Riley, B. P., Dumur, C., Vladimirov, V. I., Hesselbrock, V., Edenberg, H. J., & 29 othersNurnberger, J., Foroud, T., Kuperman, S., Kramer, J., Porjesz, B., Bierut, L., Goate, A., Rice, J., Bucholz, K., Schuckit, M., Tischfield, J., Almasy, L., Taylor, R., Dick, D., Bauer, L., Koller, D., O'Connor, S., Wetherill, L., Xuei, X., Chan, G., Kang, S., Manz, N., Rangaswamy, M., Rohrbaugh, J., Wang, J. C., Brooks, A., Aliev, F., Parsian, A. & Reilly, M., 18 Sep 2015, In: PLoS ONE. 10, 9, e0137671.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    60 Scopus citations

  • Lack of an association of BDNF Val66Met polymorphism and plasma BDNF with hippocampal volume and memory

    Kim, A., Fagan, A. M., Goate, A. M., Benzinger, T. L. S., Morris, J. C. & Head, D., 8 Sep 2015, In: Cognitive, Affective and Behavioral Neuroscience. 15, 3, p. 625-643 19 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    34 Scopus citations

  • Linkage analyses in Caribbean Hispanic families identify novel loci associated with familial late-onset Alzheimer's disease

    Barral, S., Cheng, R., Reitz, C., Vardarajan, B., Lee, J., Kunkle, B., Beecham, G., Cantwell, L. S., Pericak-Vance, M. A., Farrer, L. A., Haines, J. L., Goate, A. M., Foroud, T., Boerwinkle, E., Schellenberg, G. D. & Mayeux, R., 1 Dec 2015, In: Alzheimer's and Dementia. 11, 12, p. 1397-1406 10 p.

    Research output: Contribution to journal › Article › peer-review

    19 Scopus citations

  • Peroxisome Proliferator-Activated Receptors α and γ are Linked with Alcohol Consumption in Mice and Withdrawal and Dependence in Humans

    Blednov, Y. A., Benavidez, J. M., Black, M., Ferguson, L. B., Schoenhard, G. L., Goate, A. M., Edenberg, H. J., Wetherill, L., Hesselbrock, V., Foroud, T. & Adron Harris, R., 1 Jan 2015, In: Alcoholism: Clinical and Experimental Research. 39, 1, p. 136-145 10 p.

    Research output: Contribution to journal › Article › peer-review

    69 Scopus citations

  • Positive selection on loci associated with drug and alcohol dependence

    Sadler, B., Haller, G., Edenberg, H., Tischfield, J., Brooks, A., Kramer, J., Schuckit, M., Nurnberger, J. & Goate, A., 13 Aug 2015, In: PLoS ONE. 10, 8, e0134393.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    4 Scopus citations

  • Quantitative Interaction Proteomics of Neurodegenerative Disease Proteins

    the Genetic and Environmental Risk for Alzheimer’s Disease (GERAD1) Consortium, 19 May 2015, In: Cell Reports. 11, 7, p. 1134-1146 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    66 Scopus citations

  • Rarity of the alzheimer disease-protective APP A673T variant in the United States

    National Institute on Aging-Late-Onset Alzheimer's Disease (NIA-LOAD) Family Study & Alzheimer's Disease Genetics Consortium, 1 Feb 2015, In: JAMA Neurology. 72, 2, p. 209-216 8 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    30 Scopus citations

  • TREM2 is associated with increased risk for Alzheimer's disease in African Americans

    Jin, S. C., Carrasquillo, M. M., Benitez, B. A., Skorupa, T., Carrell, D., Patel, D., Lincoln, S., Krishnan, S., Kachadoorian, M., Reitz, C., Mayeux, R., Wingo, T. S., Lah, J. J., Levey, A. I., Murrell, J., Hendrie, H., Foroud, T., Graff-Radford, N. R., Goate, A. M., Cruchaga, C., & 1 othersErtekin-Taner, N., 10 Apr 2015, In: Molecular Neurodegeneration. 10, 1, 19.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    104 Scopus citations