Alison Goate

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Alison Goate

DPhil

 https://orcid.org/0000-0002-0576-2472
Calculated based on number of publications stored in Pure and citations from Scopus
1987 …2023

Research activity per year

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Search results

  • 2018

    Longitudinal cognitive and biomarker changes in dominantly inherited Alzheimer disease

    McDade, E., Wang, G., Gordon, B. A., Hassenstab, J., Benzinger, T. L. S., Buckles, V., Fagan, A. M., Holtzman, D. M., Cairns, N. J., Goate, A. M., Marcus, D. S., Morris, J. C., Paumier, K., Xiong, C., Allegri, R., Berman, S. B., Klunk, W., Noble, J., Ringman, J., Ghetti, B., & 12 othersFarlow, M., Sperling, R. A., Chhatwal, J., Salloway, S., Graff-Radford, N. R., Schofield, P. R., Masters, C., Rossor, M. N., Fox, N. C., Levin, J., Jucker, M. & Bateman, R. J., 2 Oct 2018, In: Neurology. 91, 14, p. E1295-E1306

    Research output: Contribution to journal › Article › peer-review

    157 Scopus citations

  • Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of CSF1R and NOTCH3

    ARUK Consortium, 1 Jun 2018, In: Neurobiology of Aging. 66, p. 179.e17-179.e29

    Research output: Contribution to journal › Article › peer-review

    Open Access
    28 Scopus citations

  • Nicotine dependence is associated with functional variation in FMO3, an enzyme that metabolizes nicotine in the brain

    Teitelbaum, A. M., Murphy, S. E., Akk, G., Baker, T. B., Germann, A., Von Weymarn, L. B., Bierut, L. J., Goate, A., Kharasch, E. D. & Bloom, A. J., 1 Jan 2018, In: Pharmacogenomics Journal. 18, 1, p. 136-143 8 p.

    Research output: Contribution to journal › Article › peer-review

    10 Scopus citations

  • Paired Immunoglobulin-like Type 2 Receptor Alpha G78R variant alters ligand binding and confers protection to Alzheimer's disease

    Rathore, N., Ramani, S. R., Pantua, H., Payandeh, J., Bhangale, T., Wuster, A., Kapoor, M., Sun, Y., Kapadia, S. B., Gonzalez, L., Zarrin, A. A., Goate, A., Hansen, D. V., Behrens, T. W. & Graham, R. R., Nov 2018, In: PLoS Genetics. 14, 11, e1007427.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    38 Scopus citations

  • Polygenic risk score of sporadic late-onset Alzheimer's disease reveals a shared architecture with the familial and early-onset forms

    the, Dominantly Inherited Alzheimer Network (DIAN), Disease Neuroimaging Initiative (ADNI) & NIA-LOAD family study, Feb 2018, In: Alzheimer's and Dementia. 14, 2, p. 205-214 10 p.

    Research output: Contribution to journal › Article › peer-review

    72 Scopus citations

  • Presymptomatic atrophy in autosomal dominant Alzheimer's disease: A serial magnetic resonance imaging study

    for the & Dominantly Inherited Alzheimer Network (DIAN), Jan 2018, In: Alzheimer's and Dementia. 14, 1, p. 43-53 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    33 Scopus citations

  • Rare genetic variation implicated in non-Hispanic white families with Alzheimer disease

    Beecham, G. W., Vardarajan, B., Blue, E., Bush, W., Jaworski, J., Barral, S., Stefano, A. D., Hamilton-Nelson, K., Kunkle, B., Martin, E. R., Naj, A., Pericak-Vance, M. A., Reitz, C., Thornton, T., Duijn, C. V., Goate, A., Seshadri, S., Farrer, L. A., Boerwinkle, E., Schellenberg, G., & 4 othersHaines, J. L., Wijsman, E., Mayeux, R. & Pericak-Vance, M. A., 1 Dec 2018, In: Neurology: Genetics. 4, 6, e286.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    15 Scopus citations

  • Sex-specific association of apolipoprotein e with cerebrospinal fluid levels of tau

    Alzheimer's Disease Genetics Consortium and the Alzheimer's Disease Neuroimaging Initiative, 1 Aug 2018, In: JAMA Neurology. 75, 8, p. 989-998 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    165 Scopus citations

  • Sex-specific genetic predictors of Alzheimer’s disease biomarkers

    Alzheimer’s Disease Neuroimaging Initiative (ADNI) & The Alzheimer Disease Genetics Consortium (ADGC), 1 Dec 2018, In: Acta Neuropathologica. 136, 6, p. 857-872 16 p.

    Research output: Contribution to journal › Article › peer-review

    55 Scopus citations

  • Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

    23andMe Research Team, 1 Dec 2018, In: Nature Neuroscience. 21, 12, p. 1656-1669 14 p.

    Research output: Contribution to journal › Article › peer-review

    284 Scopus citations

  • Untangling Genetic Risk for Alzheimer's Disease

    Pimenova, A. A., Raj, T. & Goate, A. M., 15 Feb 2018, In: Biological Psychiatry. 83, 4, p. 300-310 11 p.

    Research output: Contribution to journal › Review article › peer-review

    124 Scopus citations

  • Utility of perfusion PET measures to assess neuronal injury in Alzheimer's disease

    Dominantly Inherited Alzheimer Network, 1 Jan 2018, In: Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 10, p. 669-677 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    16 Scopus citations

  • Ventral striatal regulation of CREM mediates impulsive action and drug addiction vulnerability

    Miller, M. L., Ren, Y., Szutorisz, H., Warren, N. A., Tessereau, C., Egervari, G., Mlodnicka, A., Kapoor, M., Chaarani, B., Morris, C. V., Schumann, G., Garavan, H., Goate, A. M., Bannon, M. J., Halperin, J. M. & Hurd, Y. L., 1 May 2018, In: Molecular Psychiatry. 23, 5, p. 1328-1335 8 p.

    Research output: Contribution to journal › Article › peer-review

    17 Scopus citations

  • White matter diffusion alterations precede symptom onset in autosomal dominant Alzheimer's disease

    Caballero, M. Á. A., Suárez-Calvet, M., Duering, M., Franzmeier, N., Benzinger, T., Fagan, A. M., Bateman, R. J., Jack, C. R., Levin, J., Dichgans, M., Jucker, M., Karch, C., Masters, C. L., Morris, J. C., Weiner, M., Rossor, M., Fox, N. C., Lee, J. H., Salloway, S., Danek, A., & 6 othersGoate, A., Yakushev, I., Hassenstab, J., Schofield, P. R., Haass, C. & Ewers, M., 1 Oct 2018, In: Brain. 141, 10, p. 3065-3080 16 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    89 Scopus citations

  • Whole genome sequencing of Caribbean Hispanic families with late-onset Alzheimer's disease

    The Alzheimer's Disease Sequencing Project, 1 Apr 2018, In: Annals of Clinical and Translational Neurology. 5, 4, p. 406-417 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    27 Scopus citations
  • 2017

    A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease

    Huang, K. L., Marcora, E., Pimenova, A. A., Di Narzo, A. F., Kapoor, M., Jin, S. C., Harari, O., Bertelsen, S., Fairfax, B. P., Czajkowski, J., Chouraki, V., Grenier-Boley, B., Bellenguez, C., Deming, Y., McKenzie, A., Raj, T., Renton, A. E., Budde, J., Smith, A., Fitzpatrick, A., & 27 othersBis, J. C., DeStefano, A., Adams, H. H. H., Ikram, M. A., Van Der Lee, S., Del-Aguila, J. L., Fernandez, M. V., Ibañez, L., Sims, R., Escott-Price, V., Mayeux, R., Haines, J. L., Farrer, L. A., Pericak-Vance, M. A., Lambert, J. C., Van Duijn, C., Launer, L., Seshadri, S., Williams, J., Amouyel, P., Schellenberg, G. D., Zhang, B., Borecki, I., Kauwe, J. S. K., Cruchaga, C., Hao, K. & Goate, A. M., 1 Aug 2017, In: Nature Neuroscience. 20, 8, p. 1052-1061 10 p.

    Research output: Contribution to journal › Article › peer-review

    227 Scopus citations

  • A Common Variant of IL-6R is Associated with Elevated IL-6 Pathway Activity in Alzheimer's Disease Brains

    Haddick, P. C. G., Larson, J. L., Rathore, N., Bhangale, T. R., Phung, Q. T., Srinivasan, K., Hansen, D. V., Lill, J. R., Pericak-Vance, M. A., Haines, J., Farrer, L. A., Kauwe, J. S., Schellenberg, G. D., Cruchaga, C., Goate, A. M., Behrens, T. W., Watts, R. J., Graham, R. R., Kaminker, J. S. & Van Der Brug, M., 2017, In: Journal of Alzheimer's Disease. 56, 3, p. 1037-1054 18 p.

    Research output: Contribution to journal › Article › peer-review

    32 Scopus citations

  • A genome wide association study of fast beta EEG in families of European ancestry

    Meyers, J. L., Zhang, J., Manz, N., Rangaswamy, M., Kamarajan, C., Wetherill, L., Chorlian, D. B., Kang, S. J., Bauer, L., Hesselbrock, V., Kramer, J., Kuperman, S., Nurnberger, J. I., Tischfield, J., Wang, J. C., Edenberg, H. J., Goate, A., Foroud, T. & Porjesz, B., 1 May 2017, In: International Journal of Psychophysiology. 115, p. 74-85 12 p.

    Research output: Contribution to journal › Article › peer-review

    6 Scopus citations

  • Analysis of neurodegenerative Mendelian genes in clinically diagnosed Alzheimer Disease

    NIA-LOAD family study group & NCRAD, Nov 2017, In: PLoS Genetics. 13, 11, e1007045.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    22 Scopus citations

  • An Efficient Platform for Astrocyte Differentiation from Human Induced Pluripotent Stem Cells

    TCW, J., Wang, M., Pimenova, A. A., Bowles, K. R., Hartley, B. J., Lacin, E., Machlovi, S. I., Abdelaal, R., Karch, C. M., Phatnani, H., Slesinger, P. A., Zhang, B., Goate, A. M. & Brennand, K. J., 8 Aug 2017, In: Stem Cell Reports. 9, 2, p. 600-614 15 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    193 Scopus citations

  • An endophenotype approach to the genetics of alcohol dependence: A genome wide association study of fast beta EEG in families of African ancestry

    Meyers, J. L., Zhang, J., Wang, J. C., Su, J., Kuo, S. I., Kapoor, M., Wetherill, L., Bertelsen, S., Lai, D., Salvatore, J. E., Kamarajan, C., Chorlian, D., Agrawal, A., Almasy, L., Bauer, L., Bucholz, K. K., Chan, G., Hesselbrock, V., Koganti, L., Kramer, J., & 11 othersKuperman, S., Manz, N., Pandey, A., Seay, M., Scott, D., Taylor, R. E., Dick, D. M., Edenberg, H. J., Goate, A., Foroud, T. & Porjesz, B., 1 Dec 2017, In: Molecular Psychiatry. 22, 12, p. 1767-1775 9 p.

    Research output: Contribution to journal › Article › peer-review

    23 Scopus citations

  • A Tale of Two Genes: Microglial Apoe and Trem2

    Pimenova, A. A., Marcora, E. & Goate, A. M., 19 Sep 2017, In: Immunity. 47, 3, p. 398-400 3 p.

    Research output: Contribution to journal › Short survey › peer-review

    Open Access
    38 Scopus citations

  • Clinical/Scientific Notes: The Alzheimer's disease sequencing project: Study design and sample selection

    Beecham, G. W., Bis, J. C., Martin, E. R., Choi, S. H., DeStefano, A. L., Van Duijn, C. M., Fornage, M., Gabriel, S. B., Koboldt, D. C., Larson, D. E., Naj, A. C., Psaty, B. M., Salerno, W., Bush, W. S., Foroud, T. M., Wijsman, E., Farrer, L. A., Goate, A., Haines, J. L., Pericak-Vance, M. A., & 4 othersBoerwinkle, E., Mayeux, R., Seshadri, S. & Schellenberg, G., 1 Oct 2017, In: Neurology: Genetics. 3, 5, e194.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    74 Scopus citations

  • Differentiating cognitive impairment due to corticobasal degeneration and Alzheimer disease

    Day, G. S., Lim, T. S., Hassenstab, J., Goate, A. M., Grant, E. A., Roe, C. M., Cairns, N. J. & Morris, J. C., 28 Mar 2017, In: Neurology. 88, 13, p. 1273-1281 9 p.

    Research output: Contribution to journal › Article › peer-review

    29 Scopus citations

  • Discovery and functional prioritization of Parkinson's disease candidate genes from large-scale whole exome sequencing

    International Parkinson's Disease Genetics Consortium (IPGDC), 30 Jan 2017, In: Genome Biology. 18, 1, 22.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    75 Scopus citations

  • Erratum: The Rare-Variant Generalized Disequilibrium Test for Association Analysis of Nuclear and Extended Pedigrees with Application to Alzheimer Disease WGS Data (American Journal of Human Genetics (2017) 100(2) (193–204)(S0002929716305250)(10.1016/j.ajhg.2016.12.001)

    He, Z., Zhang, D., Renton, A. E., Li, B., Zhao, L., Wang, G. T., Goate, A. M., Mayeux, R. & Leal, S. M., 2 Feb 2017, In: American Journal of Human Genetics. 100, 2, p. 371 1 p.

    Research output: Contribution to journal › Comment/debate

    Open Access
    1 Scopus citations

  • Excessive burden of lysosomal storage disorder gene variants in Parkinson's disease

    Robak, L. A., Jansen, I. E., Rooij, J. V., Uitterlinden, A. G., Kraaij, R., Jankovic, J., Heutink, P., Shulman, J. M., Nalls, M. A., Plagnol, V., Hernandez, D. G., Sharma, M., Sheerin, U. M., Saad, M., Simón-Sánchez, J., Schulte, C., Lesage, S., Sveinbjörnsdóttir, S., Arepalli, S., Barker, R., & 119 othersBen, Y., Berendse, H. W., Berg, D., Bhatia, K., de Bie, R. M. A., Biffi, A., Bloem, B., Bochdanovits, Z., Bonin, M., Bras, J. M., Brockmann, K., Brooks, J., Burn, D. J., Majounie, E., Charlesworth, G., Lungu, C., Chen, H., Chinnery, P. F., Chong, S., Clarke, C. E., Cookson, M. R., Cooper, J. M., Corvol, J. C., Counsell, C., Damier, P., Dartigues, J. F., Deloukas, P., Deuschl, G., Dexter, D. T., van Dijk, K. D., Dillman, A., Durif, F., Dürr, A., Edkins, S., Evans, J. R., Foltynie, T., Dong, J., Gardner, M., Gibbs, J. R., Goate, A., Gray, E., Guerreiro, R., Harris, C., van Hilten, J. J., Hofman, A., Hollenbeck, A., Holton, J., Hu, M., Huang, X., Wurster, I., Mätzler, W., Hudson, G., Hunt, S. E., Huttenlocher, J., Illig, T., Jónsson, P. V., Lambert, J. C., Langford, C., Lees, A., Lichtner, P., Limousin, P., Lopez, G., Lorenz, D., Lungu, C., McNeill, A., Moorby, C., Moore, M., Morris, H. R., Morrison, K. E., Escott-Price, V., Mudanohwo, E., O’sullivan, S. S., Pearson, J., Perlmutter, J. S., Pétursson, H., Pollak, P., Post, B., Potter, S., Ravina, B., Revesz, T., Riess, O., Rivadeneira, F., Rizzu, P., Ryten, M., Sawcer, S., Schapira, A., Scheffer, H., Shaw, K., Shoulson, I., Shulman, J., Sidransky, E., Smith, C., Spencer, C. C. A., Stefánsson, H., Bettella, F., Stockton, J. D., Strange, A., Talbot, K., Tanner, C. M., Tashakkori-Ghanbaria, A., Tison, F., Trabzuni, D., Traynor, B. J., Velseboer, D., Vidailhet, M., Walker, R., Warrenburg, B. V. D., Wickremaratchi, M., Williams, N., Williams-Gray, C. H., Winder-Rhodes, S., Stefánsson, K., Martinez, M., Wood, N. W., Hardy, J., Heutink, P., Brice, A., Gasser, T. & Singleton, A. B., 1 Dec 2017, In: Brain. 140, 12, p. 3191-3203 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    247 Scopus citations

  • Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score

    Desikan, R. S., Fan, C. C., Wang, Y., Schork, A. J., Cabral, H. J., Cupples, L. A., Thompson, W. K., Besser, L., Kukull, W. A., Holland, D., Chen, C. H., Brewer, J. B., Karow, D. S., Kauppi, K., Witoelar, A., Karch, C. M., Bonham, L. W., Yokoyama, J. S., Rosen, H. J., Miller, B. L., & 14 othersDillon, W. P., Wilson, D. M., Hess, C. P., Pericak-Vance, M., Haines, J. L., Farrer, L. A., Mayeux, R., Hardy, J., Goate, A. M., Hyman, B. T., Schellenberg, G. D., McEvoy, L. K., Andreassen, O. A. & Dale, A. M., Mar 2017, In: PLoS Medicine. 14, 3, e1002258.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    229 Scopus citations

  • Genetic Comparison of Symptomatic and Asymptomatic Persons With Alzheimer Disease Neuropathology

    Monsell, S. E., Mock, C., Fardo, D. W., Bertelsen, S., Cairns, N. J., Roe, C. M., Ellingson, S. R., Morris, J. C., Goate, A. M. & Kukull, W. A., 2017, In: Alzheimer Disease and Associated Disorders. 31, 3, p. 232-238 7 p.

    Research output: Contribution to journal › Article › peer-review

    12 Scopus citations

  • Genetics of β-amyloid precursor protein in alzheimer’s disease

    Julia, T. C. W. & Goate, A. M., Jun 2017, In: Cold Spring Harbor Perspectives in Medicine. 7, 6, a024539.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    44 Scopus citations

  • Genome-wide, high-content siRNA screening identifies the Alzheimer’s genetic risk factor FERMT2 as a major modulator of APP metabolism

    ADGC, Alzheimer’s Disease Neuroimaging Initiative, 1 Jun 2017, In: Acta Neuropathologica. 133, 6, p. 955-966 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    38 Scopus citations

  • Genome-wide association study identifies four novel loci associated with Alzheimer’s endophenotypes and disease modifiers

    Alzheimer’s Disease Neuroimaging Initiative (ADNI) & The Alzheimer Disease Genetic Consortium (ADGC), 1 May 2017, In: Acta Neuropathologica. 133, 5, p. 839-856 18 p.

    Research output: Contribution to journal › Article › peer-review

    123 Scopus citations

  • Genomewide Association Study of Alcohol Dependence Identifies Risk Loci Altering Ethanol-Response Behaviors in Model Organisms

    Collaborative Study of the Genetics of Alcoholism Consortium & the German Study of the Genetics of Addiction Consortium, May 2017, In: Alcoholism: Clinical and Experimental Research. 41, 5, p. 911-928 18 p.

    Research output: Contribution to journal › Article › peer-review

    34 Scopus citations

  • Genome-wide pleiotropy between Parkinson disease and autoimmune diseases

    for the International Parkinson's Disease Genomics Consortium (IPDGC), United Kingdom Brain Expression Consortium (UKBEC) Investigators, North American Brain Expression Consortium (NABEC), Jul 2017, In: JAMA Neurology. 74, 7, p. 780-792 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    171 Scopus citations

  • Late onset Alzheimer's disease genetics implicates microglial pathways in disease risk

    Efthymiou, A. G. & Goate, A. M., 26 May 2017, In: Molecular Neurodegeneration. 12, 1, 43.

    Research output: Contribution to journal › Review article › peer-review

    Open Access
    293 Scopus citations

  • Linkage, whole genome sequence, and biological data implicate variants in RAB10 in Alzheimer's disease resilience

    for the Alzheimer's Disease Neuroimaging Initative, 29 Nov 2017, In: Genome Medicine. 9, 1, 100.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    47 Scopus citations

  • No genetic association between attention-deficit/hyperactivity disorder (ADHD) and Parkinson’s disease in nine ADHD candidate SNPs

    International Parkinson Disease Genomics Consortium members, 1 Jun 2017, In: ADHD Attention Deficit and Hyperactivity Disorders. 9, 2, p. 121-127 7 p.

    Research output: Contribution to journal › Article › peer-review

    10 Scopus citations

  • Polygenic risk scores in familial Alzheimer disease

    Tosto, G., Bird, T. D., Tsuang, D., Bennett, D. A., Boeve, B. F., Cruchaga, C., Faber, K., Foroud, T. M., Farlow, M., Goate, A. M., Bertlesen, S., Graff-Radford, N. R., Medrano, M., Lantigua, R., Manly, J., Ottman, R., Rosenberg, R., Schaid, D. J., Schupf, N., Stern, Y., & 2 othersSweet, R. A. & Mayeux, R., 21 Mar 2017, In: Neurology. 88, 12, p. 1180-1186 7 p.

    Research output: Contribution to journal › Article › peer-review

    40 Scopus citations

  • Polygenic Scores for Major Depressive Disorder and Risk of Alcohol Dependence

    Andersen, A. M., Pietrzak, R. H., Kranzler, H. R., Ma, L., Zhou, H., Liu, X., Kramer, J., Kuperman, S., Edenberg, H. J., Nurnberger, J. I., Rice, J. P., Tischfield, J. A., Goate, A., Foroud, T. M., Meyers, J. L., Porjesz, B., Dick, D. M., Hesselbrock, V., Boerwinkle, E., Southwick, S. M., & 6 othersKrystal, J. H., Weissman, M. M., Levinson, D. F., Potash, J. B., Gelernter, J. & Han, S., 1 Nov 2017, In: JAMA Psychiatry. 74, 11, p. 1153-1160 8 p.

    Research output: Contribution to journal › Article › peer-review

    61 Scopus citations

  • Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

    Sims, R., Van Der Lee, S. J., Naj, A. C., Bellenguez, C., Badarinarayan, N., Jakobsdottir, J., Kunkle, B. W., Boland, A., Raybould, R., Bis, J. C., Martin, E. R., Grenier-Boley, B., Heilmann-Heimbach, S., Chouraki, V., Kuzma, A. B., Sleegers, K., Vronskaya, M., Ruiz, A., Graham, R. R., Olaso, R., & 426 othersHoffmann, P., Grove, M. L., Vardarajan, B. N., Hiltunen, M., Nöthen, M. M., White, C. C., Hamilton-Nelson, K. L., Epelbaum, J., Maier, W., Choi, S. H., Beecham, G. W., Dulary, C., Herms, S., Smith, A. V., Funk, C. C., Derbois, C., Forstner, A. J., Ahmad, S., Li, H., Bacq, D., Harold, D., Satizabal, C. L., Valladares, O., Squassina, A., Thomas, R., Brody, J. A., Qu, L., Sánchez-Juan, P., Morgan, T., Wolters, F. J., Zhao, Y., Garcia, F. S., Denning, N., Fornage, M., Malamon, J., Naranjo, M. C. D., Majounie, E., Mosley, T. H., Dombroski, B., Wallon, D., Lupton, M. K., Dupuis, J., Whitehead, P., Fratiglioni, L., Medway, C., Jian, X., Mukherjee, S., Keller, L., Brown, K., Lin, H., Cantwell, L. B., Panza, F., McGuinness, B., Moreno-Grau, S., Burgess, J. D., Solfrizzi, V., Proitsi, P., Adams, H. H., Allen, M., Seripa, D., Pastor, P., Cupples, L. A., Price, N. D., Hannequin, D., Frank-García, A., Levy, D., Chakrabarty, P., Caffarra, P., Giegling, I., Beiser, A. S., Giedraitis, V., Hampel, H., Garcia, M. E., Wang, X., Lannfelt, L., Mecocci, P., Eiriksdottir, G., Crane, P. K., Pasquier, F., Boccardi, V., Henández, I., Barber, R. C., Scherer, M., Tarraga, L., Adams, P. M., Leber, M., Chen, Y., Albert, M. S., Riedel-Heller, S., Emilsson, V., Beekly, D., Braae, A., Schmidt, R., Blacker, D., Masullo, C., Schmidt, H., Doody, R. S., Spalletta, G., Longstreth, W. T., Fairchild, T. J., Bossù, P., Lopez, O. L., Frosch, M. P., Sacchinelli, E., Ghetti, B., Yang, Q., Huebinger, R. M., Jessen, F., Li, S., Kamboh, M. I., Morris, J. C., Sotolongo-Grau, O., Katz, M. J., Corcoran, C., Dunstan, M., Braddel, A., Thomas, C., Meggy, A., Marshall, R., Gerrish, A., Chapman, J., Aguilar, M., Taylor, S., Hill, M., Fairén, M. D., Hodges, A., Vellas, B., Soininen, H., Kloszewska, I., Daniilidou, M., Uphill, J., Patel, Y., Hughes, J. T., Lord, J., Turton, J., Hartmann, A. M., Cecchetti, R., Fenoglio, C., Serpente, M., Arcaro, M., Caltagirone, C., Orfei, M. D., Ciaramella, A., Pichler, S., Mayhaus, M., Gu, W., Lleó, A., Fortea, J., Blesa, R., Barber, I. S., Brookes, K., Cupidi, C., Maletta, R. G., Carrell, D., Sorbi, S., Moebus, S., Urbano, M., Pilotto, A., Kornhuber, J., Bosco, P., Todd, S., Craig, D., Johnston, J., Gill, M., Lawlor, B., Lynch, A., Fox, N. C., Hardy, J., Albin, R. L., Apostolova, L. G., Arnold, S. E., Asthana, S., Atwood, C. S., Baldwin, C. T., Barnes, L. L., Barral, S., Beach, T. G., Becker, J. T., Bigio, E. H., Bird, T. D., Boeve, B. F., Bowen, J. D., Boxer, A., Burke, J. R., Burns, J. M., Buxbaum, J. D., Cairns, N. J., Cao, C., Carlson, C. S., Carlsson, C. M., Carney, R. M., Carrasquillo, M. M., Carroll, S. L., Diaz, C. C., Chui, H. C., Clark, D. G., Cribbs, D. H., Crocco, E. A., Decarli, C., Dick, M., Duara, R., Evans, D. A., Faber, K. M., Fallon, K. B., Fardo, D. W., Farlow, M. R., Ferris, S., Foroud, T. M., Galasko, D. R., Gearing, M., Geschwind, D. H., Gilbert, J. R., Graff-Radford, N. R., Green, R. C., Growdon, J. H., Hamilton, R. L., Harrell, L. E., Honig, L. S., Huentelman, M. J., Hulette, C. M., Hyman, B. T., Jarvik, G. P., Abner, E., Jin, L. W., Jun, G., Karydas, A., Kaye, J. A., Kim, R., Kowall, N. W., Kramer, J. H., Laferla, F. M., Lah, J. J., Leverenz, J. B., Levey, A. I., Li, G., Lieberman, A. P., Lunetta, K. L., Lyketsos, C. G., Marson, D. C., Martiniuk, F., Mash, D. C., Masliah, E., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Murrell, J. R., Myers, A. J., O'Bryant, S., Olichney, J. M., Pankratz, V. S., Parisi, J. E., Paulson, H. L., Perry, W., Peskind, E., Pierce, A., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Raskind, M., Reisberg, B., Reitz, C., Ringman, J. M., Roberson, E. D., Rogaeva, E., Rosen, H. J., Rosenberg, R. N., Sager, M. A., Saykin, A. J., Schneider, J. A., Schneider, L. S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., Stern, R. A., Swerdlow, R. H., Tanzi, R. E., Thornton-Wells, T. A., Trojanowski, J. Q., Troncoso, J. C., Van Deerlin, V. M., Van Eldik, L. J., Vinters, H. V., Vonsattel, J. P., Weintraub, S., Welsh-Bohmer, K. A., Wilhelmsen, K. C., Williamson, J., Wingo, T. S., Woltjer, R. L., Wright, C. B., Yu, C. E., Yu, L., Garzia, F., Golamaully, F., Septier, G., Engelborghs, S., Vandenberghe, R., De Deyn, P. P., Fernadez, C. M., Benito, Y. A., Thonberg, H., Forsell, C., Lilius, L., Kinhult-Stählbom, A., Kilander, L., Brundin, R., Concari, L., Helisalmi, S., Koivisto, A. M., Haapasalo, A., Dermecourt, V., Fievet, N., Hanon, O., Dufouil, C., Brice, A., Ritchie, K., Dubois, B., Himali, J. J., Keene, C. D., Tschanz, J., Fitzpatrick, A. L., Kukull, W. A., Norton, M., Aspelund, T., Larson, E. B., Munger, R., Rotter, J. I., Lipton, R. B., Bullido, M. J., Hofman, A., Montine, T. J., Coto, E., Boerwinkle, E., Petersen, R. C., Alvarez, V., Rivadeneira, F., Reiman, E. M., Gallo, M., O'Donnell, C. J., Reisch, J. S., Bruni, A. C., Royall, D. R., Dichgans, M., Sano, M., Galimberti, D., St George-Hyslop, P., Scarpini, E., Tsuang, D. W., Mancuso, M., Bonuccelli, U., Winslow, A. R., Daniele, A., Wu, C. K., Peters, O., Nacmias, B., Riemenschneider, M., Heun, R., Brayne, C., Rubinsztein, D. C., Bras, J., Guerreiro, R., Al-Chalabi, A., Shaw, C. E., Collinge, J., Mann, D., Clarimón, J., Sussams, R., Lovestone, S., O'Donovan, M. C., Owen, M. J., Behrens, T. W., Mead, S., Uitterlinden, A. G., Holmes, C., Cruchaga, C., Ingelsson, M., Bennett, D. A., Powell, J., Golde, T. E., Graff, C., De Jager, P. L., Morgan, K., Ertekin-Taner, N., Combarros, O., Psaty, B. M., Passmore, P., Younkin, S. G., Berr, C., Gudnason, V., Rujescu, D., Dickson, D. W., Dartigues, J. F., Destefano, A. L., Ortega-Cubero, S., Hakonarson, H., Campion, D., Boada, M., Kauwe, J. K., Farrer, L. A., Van Broeckhoven, C., Ikram, M. A., Jones, L., Haines, J. L., Tzourio, C., Launer, L. J., Escott-Price, V., Mayeux, R., Deleuze, J. F., Amin, N., Goate, A. M., Pericak-Vance, M. A., Holmans, P. A., Van Duijn, C. M., Ramirez, A., Wang, L. S., Lambert, J. C., Seshadri, S., Williams, J. & Schellenberg, G. D., 1 Sep 2017, In: Nature Genetics. 49, 9, p. 1373-1384 12 p.

    Research output: Contribution to journal › Article › peer-review

    550 Scopus citations

  • The Impact of Peer Substance Use and Polygenic Risk on Trajectories of Heavy Episodic Drinking Across Adolescence and Emerging Adulthood

    COGA Investigators, 1 Jan 2017, In: Alcoholism: Clinical and Experimental Research. 41, 1, p. 65-75 11 p.

    Research output: Contribution to journal › Article › peer-review

    21 Scopus citations

  • The Rare-Variant Generalized Disequilibrium Test for Association Analysis of Nuclear and Extended Pedigrees with Application to Alzheimer Disease WGS Data

    He, Z., Zhang, D., Renton, A. E., Li, B., Zhao, L., Wang, G. T., Goate, A. M., Mayeux, R. & Leal, S. M., 2 Feb 2017, In: American Journal of Human Genetics. 100, 2, p. 193-204 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    15 Scopus citations

  • Transethnic genome-wide scan identifies novel Alzheimer's disease loci

    Alzheimer's Disease Genetics Consortium, 1 Jul 2017, In: Alzheimer's and Dementia. 13, 7, p. 727-738 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    102 Scopus citations

  • Two novel loci, COBL and SLC10A2, for Alzheimer's disease in African Americans

    Alzheimer's Disease Genetics Consortium, 1 Feb 2017, In: Alzheimer's and Dementia. 13, 2, p. 119-129 11 p.

    Research output: Contribution to journal › Article › peer-review

    55 Scopus citations

  • Variation in SWI/SNF Chromatin Remodeling Complex Proteins is Associated with Alcohol Dependence and Antisocial Behavior in Human Populations

    COGA Investigators, Dec 2017, In: Alcoholism: Clinical and Experimental Research. 41, 12, p. 2033-2040 8 p.

    Research output: Contribution to journal › Article › peer-review

    10 Scopus citations
  • 2016

    ABCA7 p.G215S as potential protective factor for Alzheimer's disease

    Sassi, C., Nalls, M. A., Ridge, P. G., Gibbs, J. R., Ding, J., Lupton, M. K., Troakes, C., Lunnon, K., Al-Sarraj, S., Brown, K. S., Medway, C., Clement, N., Lord, J., Turton, J., Bras, J., Almeida, M. R., Passmore, P., Craig, D., Johnston, J., McGuinness, B., & 29 othersTodd, S., Heun, R., Kölsch, H., Kehoe, P. G., Vardy, E. R. L. C., Hooper, N. M., Mann, D. M., Pickering-Brown, S., Brown, K., Lowe, J., Morgan, K., Smith, A. D., Wilcock, G., Warden, D., Holmes, C., Holstege, H., Louwersheimer, E., van der Flier, W. M., Scheltens, P., Van Swieten, J. C., Santana, I., Oliveira, C., Powell, J. F., Kauwe, J. S., Cruchaga, C., Goate, A. M., Singleton, A. B., Guerreiro, R. & Hardy, J., 1 Oct 2016, In: Neurobiology of Aging. 46, p. 235.e1-235.e9

    Research output: Contribution to journal › Article › peer-review

    Open Access
    36 Scopus citations

  • Alzheimer's disease risk polymorphisms regulate gene expression in the ZCWPW1 and the CELF1 loci

    Alzheimer's Disease Genetics Consortium (ADGC), Feb 2016, In: PLoS ONE. 11, 2, e0148717.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    68 Scopus citations

  • A novel Alzheimer disease locus located near the gene encoding tau protein

    Jun, G., Ibrahim-Verbaas, C. A., Vronskaya, M., Lambert, J. C., Chung, J., Naj, A. C., Kunkle, B. W., Wang, L. S., Bis, J. C., Bellenguez, C., Harold, D., Lunetta, K. L., Destefano, A. L., Grenier-Boley, B., Sims, R., Beecham, G. W., Smith, A. V., Chouraki, V., Hamilton-Nelson, K. L., Ikram, M. A., & 332 othersFievet, N., Denning, N., Martin, E. R., Schmidt, H., Kamatani, Y., Dunstan, M. L., Valladares, O., Laza, A. R., Zelenika, D., Ramirez, A., Foroud, T. M., Choi, S. H., Boland, A., Becker, T., Kukull, W. A., Van Der Lee, S. J., Pasquier, F., Cruchaga, C., Beekly, D., Fitzpatrick, A. L., Hanon, O., Gill, M., Barber, R., Gudnason, V., Campion, D., Love, S., Bennett, D. A., Amin, N., Berr, C., Tsolaki, M., Buxbaum, J. D., Lopez, O. L., Deramecourt, V., Fox, N. C., Cantwell, L. B., Tárraga, L., Dufouil, C., Hardy, J., Crane, P. K., Eiriksdottir, G., Hannequin, D., Clarke, R., Evans, D., Mosley, T. H., Letenneur, L., Brayne, C., Maier, W., De Jager, P., Emilsson, V., Dartigues, J. F., Hampel, H., Kamboh, M. I., De Bruijn, R. F. A. G., Tzourio, C., Pastor, P., Larson, E. B., Rotter, J. I., O'Donovan, M. C., Montine, T. J., Nalls, M. A., Mead, S., Reiman, E. M., Jonsson, P. V., Holmes, C., St George-Hyslop, P. H., Boada, M., Passmore, P., Wendland, J. R., Schmidt, R., Morgan, K., Winslow, A. R., Powell, J. F., Carasquillo, M., Younkin, S. G., Jakobsdóttir, J., Kauwe, J. S. K., Wilhelmsen, K. C., Rujescu, D., Nöthen, M. M., Hofman, A., Jones, L., Haines, J. L., Psaty, B. M., Van Broeckhoven, C., Holmans, P., Launer, L. J., Mayeux, R., Lathrop, M., Goate, A. M., Escott-Price, V., Seshadri, S., Pericak-Vance, M. A., Amouyel, P., Williams, J., Van Duijn, C. M., Schellenberg, G. D., Farrer, L. A., Adams, P. M., Albert, M. S., Albin, R. L., Apostolova, L. G., Arnold, S. E., Asthana, S., Atwood, C. S., Baldwin, C. T., Barmada, M. M., Barnes, L. L., Beach, T. G., Bigio, E. H., Bird, T. D., Blacker, D., Boeve, B. F., Bowen, J. D., Boxer, A., Burke, J. R., Cairns, N. J., Cao, C., Carlson, C. S., Carlsson, C. M., Carney, R. M., Carrasquillo, M. M., Carroll, S. L., Chui, H. C., Clark, D. G., Corneveaux, J., Cribbs, D. H., Crocco, E. A., DeCarli, C., DeKosky, S. T., Yesim Demirci, F., Dick, M., Dickson, D. W., Doody, R. S., Duara, R., Ertekin-Taner, N., Faber, K. M., Fairchild, T. J., Fallon, K. B., Farlow, M. R., Ferris, S., Frosch, M. P., Galasko, D. R., Gearing, M., Geschwind, D. H., Ghetti, B., Gilbert, J. R., Glass, J. D., Graff-Radford, N. R., Green, R. C., Growdon, J. H., Hakonarson, H., Hamilton, R. L., Harrell, L. E., Head, E., Honig, L. S., Huebinger, R. M., Huentelman, M. J., Hulette, C. M., Hyman, B. T., Jarvik, G. P., Jicha, G. A., Jin, L. W., Karydas, A., Kaye, J. A., Kim, R., Koo, E. H., Kowall, N. W., Kramer, J. H., LaFerla, F. M., Lah, J. J., Leverenz, J. B., Levey, A. I., Li, G., Lieberman, A. P., Lin, C. F., Lyketsos, C. G., Mack, W. J., Marson, D. C., Martiniuk, F., Mash, D. C., Masliah, E., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Morris, J. C., Mukherjee, S., Murrell, J. R., Myers, A. J., O'Bryant, S., Olichney, J. M., Pankratz, V. S., Parisi, J. E., Partch, A., Paulson, H. L., Perry, W., Peskind, E., Petersen, R. C., Pierce, A., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Raskind, M., Reisberg, B., Reisch, J. S., Reitz, C., Ringman, J. M., Roberson, E. D., Rogaeva, E., Rosen, H. J., Rosenberg, R. N., Royall, D. R., Sager, M. A., Sano, M., Saykin, A. J., Schneider, J. A., Schneider, L. S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., Stern, R. A., Tanzi, R. E., Thornton-Wells, T. A., Trojanowski, J. Q., Troncoso, J. C., Tsuang, D. W., Van Deerlin, V. M., Van Eldik, L. J., Vardarajan, B. N., Vinters, H. V., Vonsattel, J. P., Weintraub, S., Welsh-Bohmer, K. A., Williamson, J., Wishnek, S., Woltjer, R. L., Wright, C. B., Wu, C. K., Yu, C. E., Yu, L., Thomas, C., Gerrish, A., Chapman, J., Stretton, A., Morgan, A., Oldham, H., Owen, M. J., Kehoe, P. G., Medway, C., Brown, K., Lord, J., Turton, J., Hooper, N. M., Vardy, E., Warren, J. D., Schott, J. M., Uphill, J., Hollingworth, P., Ryan, N., Rossor, M., Collinge, J., Ben-Shlomo, Y., Makrina, D., Gkatzima, O., Lupton, M., Koutroumani, M., Avramidou, D., Germanou, A., Jessen, F., Riedel-Heller, S., Dichgans, M., Heun, R., Kölsch, H., Schürmann, B., Herold, C., Lacour, A., Drichel, D., Hoffmann, P., Kornhuber, J., Gu, W., Feulner, T., Mayhaus, M., Pichler, S., Riemenschneider, M., van den Bussche, H., Lawlor, B., Lynch, A., Mann, D., Smith, A. D., Warden, D., Wilcock, G., Heuser, I., Wiltfang, J., Frölich, L., Hüll, M., Mayo, K., Livingston, G., Bass, N. J., Gurling, H., McQuillin, A., Gwilliam, R., Deloukas, P., Al-Chalabi, A., Shaw, C. E., Singleton, A. B., Guerreiro, R., Russo, G., Jöckel, K. H., Moebus, S., Klopp, N., Wichmann, H. E., Ma, L., Bisceglio, G., Fisher, E., Warner, N., Pickering-Brown, S., Craig, D., Johnston, J. A., McGuinness, B., Todd, S., Rubinsztein, D. C., Lovestone, S., Bayer, A., Gallacher, J., Proitsi, P. & Ortega-Cubero, S., 1 Jan 2016, In: Molecular Psychiatry. 21, 1, p. 108-117 10 p.

    Research output: Contribution to journal › Article › peer-review

    164 Scopus citations

  • A polygenic burden of rare variants across extracellular matrix genes among individuals with adolescent idiopathic scoliosis

    Haller, G., Alvarado, D., Mccall, K., Yang, P., Cruchaga, C., Harms, M., Goate, A., Willing, M., Morcuende, J. A., Baschal, E., Miller, N. H., Wise, C., Dobbs, M. B. & Gurnett, C. A., 1 Jan 2016, In: Human Molecular Genetics. 25, 1, p. 202-209 8 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    51 Scopus citations

  • A potential endophenotype for Alzheimer's disease: cerebrospinal fluid clusterin

    Deming, Y., Xia, J., Cai, Y., Lord, J., Holmans, P., Bertelsen, S., Holtzman, D., Morris, J. C., Bales, K., Pickering, E. H., Kauwe, J., Goate, A. & Cruchaga, C., 1 Jan 2016, In: Neurobiology of Aging. 37, p. 208.e1-208.e9

    Research output: Contribution to journal › Article › peer-review

    Open Access
    37 Scopus citations