Alice O. Kamphorst

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ASSISTANT PROFESSOR | Oncological Sciences

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43 Article
6 Review article
1 Editorial
1 Short survey

An immunocompetent murine model of virus-elicited liver fibrosis and hepatocellular carcinoma
Batista, M. N., Bordignon, J., Ana, A. L., Bobrowski, T., Chen, H. A., Tobin-Xet, G., Barrall, E. A., Prokhnevska, N., Vaidya, A. B., Lewy, T., Dinnon, K. H., Seifert, L. L., Zeck, B., Quirk, C., Ho, Y. J., Filliol, A., Wolfisberg, R., Jiang, C., Cogliati, B. & Chiriboga, L. & 9 others, Theise, N., MacDonald, M. R., Kamphorst, A. O., Troels, T. K., Sheahan, T. P., Billerbeck, E., Lowe, S. W., Rosenberg, B. R. & Rice, C. M., Jun 2026, In: Journal of Hepatology. 84, 6, p. 1062-1076 15 p.
Research output: Contribution to journal › Article › peer-review

Open Access
1 Scopus citations
Guidelines for T cell nomenclature
Masopust, D., Awasthi, A., Bosselut, R., Brooks, D. G., Buggert, M., Chamoto, K., Cui, W., Dong, C., Farber, D. L., Gebhardt, T., Gerlach, C., Goldrath, A., Greenberg, P. D., Hale, J. S., Hayday, A., Homann, D., Iannacone, M., Jameson, S. C., Jenkins, M. K. & Joshi, N. S. & 40 others, Kaech, S. M., Kallies, A., Kamphorst, A. O., Kaplan, M. H., Klenerman, P., Künzli, M., Lanzavecchia, A., Lauer, G. M., Lugli, E., Luster, A. D., Mackay, L. K., McElrath, M. J., Mueller, S. N., Ndhlovu, Z., Ndung’u, T., Ohashi, P. S., Oxenius, A., Pantaleo, G., Pepper, M., Picker, L. J., Quarnstrom, C. F., Reyes-Terán, G., Roederer, M., Rosato, P. C., de Oca, G. S. M., Sallusto, F., Schumacher, T. N., Schwartz, D. M., Shin, E. C., Soerens, A. G., Thommen, D. S., Vezys, V., Viola, J. P. B., Walker, B. D., Watts, T. H., Weaver, C. T., Wherry, E. J., Xue, H. H., Youngblood, B. & Ahmed, R., Apr 2026, In: Nature Reviews Immunology. 26, 4, p. 298-313 16 p.
Research output: Contribution to journal › Article › peer-review

Open Access
34 Scopus citations
Humoral IgG1 responses to tumor antigens underpin clinical outcomes in immune checkpoint blockade
Gonzalez-Kozlova, E., Sweeney, R., Figueiredo, I., Tuballes, K., Ozbey, S., Hamon, P., Park, M. D., Ioannou, G., Nose, Y., Guo, R., Restrepo, P., Buckup, M., Roudko, V., Hennequin, C., Le Berichel, J., Venturini, N., Halasz, L., Troncoso, L., Tabachnikova, A. & Chang, C. & 42 others, Reid, A., Brown, H., Chin, T., Cabal, R., Mattiuz, R., Eikawa, S., Del Valle, D. M., Gonsalves, T. R., LaMarche, N. M., Jamal, H., Lansky, A., Yi, N., Nelson, D., Morgenroth-Rebin, J., Merand, R., Villagomez, B., D’Souza, D., Radkevich, E., Nie, K., Chen, Z., Tada, Y., Nishikawa, H., Ward, S. C., Fiel, M. I., Brody, R., Tabrizian, P., Gunasekaran, G., Kamphorst, A. O., Cohen, N., Curotto de Lafaille, M., Hapanowicz, O., Lucas, N., Wu, K., James, N., Lin, J. C., Thurston, G., Schwartz, M., Fiaschi, N., Kim-Schulze, S., Merad, M., Marron, T. U. & Gnjatic, S., Mar 2026, In: Nature Medicine. 32, 3, p. 978-991 14 p.
Research output: Contribution to journal › Article › peer-review

Open Access
1 Scopus citations
NOTCH1 Drives Sexually Dimorphic Immune Responses in Hepatocellular Carcinoma
Lindblad, K. E., Donne, R., Liebling, I., Barcena-Varela, M., Lozano, A., Ruiz de Galarreta, M., Dhainaut, M., Param, N. J., Giotti, B., Cappuyns, S., Kodama, T., Wang, Y., Kamphorst, A. O., Tsankov, A. M. & Lujambio, A., 3 Mar 2025, In: Cancer Discovery. 15, 3, p. 495-510 16 p.
Research output: Contribution to journal › Article › peer-review

Open Access
11 Scopus citations
Prolonged but finite antigen presentation promotes reversible defects of “helpless” memory CD8⁺ T cells
van der Heide, V., Laghlali, G., Davenport, B., Cubitt, B., Roudko, V., Choo, D., Jhun, K., Humblin, E., Vaidya, A., Angeliadis, K., Dawson, T., Furtado, G., Kamphorst, A. O., Schotsaert, M., Ahmed, R., de la Torre, J. C. & Homann, D., 8 Jul 2025, In: Immunity. 58, 7, p. 1742-1761.e14
Research output: Contribution to journal › Article › peer-review

Open Access
3 Scopus citations

Findings on Immunotherapy Detailed by Investigators at Icahn School of Medicine at Mount Sinai (Humoral Igg1 Responses To Tumor Antigens Underpin Clinical Outcomes In Immune Checkpoint Blockade)
Sweeney, R., Merad, M., Nie, K., Kim-Schulze, S., D'Souza, D., Hamon, P., Tabrizian, P., Cohen, N., Gunasekaran, G., Schwartz, M., Marron, T., Fiel, M., Gnjatic, S., Ward, S., Curotto de Lafaille, M., Kamphorst, A. O., Chen, Z. & Brody, R.
23/02/26
1 item of Media coverage
Press/Media
New Proteomics Findings from Icahn School of Medicine at Mount Sinai Described (Prolonged but finite antigen presentation promotes reversible defects of "helpless" memory CD8+ T cells)
Dawson, T., Furtado, G., Schotsaert, M. & Kamphorst, A. O.
25/09/25
1 item of Media coverage
Press/Media
Studies from Rockefeller University Yield New Data on Lymphocytic Choriomeningitis Virus (Universal Recording of Immune Cell Interactions In Vivo)
Kamphorst, A. O.
23/04/24
1 item of Media coverage
Press/Media
Reports on Melanoma from Icahn School of Medicine at Mount Sinai Provide New Insights (Macroh2a Restricts Inflammatory Gene Expression In Melanoma Cancer-associated Fibroblasts By Coordinating Chromatin Looping)
Filipescu, D., Vyas, N., Sebra, R., Bernstein, E. & Kamphorst, A. O.
19/09/23
1 item of Media coverage
Press/Media
Investigators at Icahn School of Medicine at Mount Sinai Discuss Findings in Liver Cancer [Intratumoral Dendritic Cell-cd4(+) T Helper Cell Niches Enable Cd8(+) T Cell Differentiation Following Pd-1 Blockade In Hepatocellular Carcinoma]
Hegde, S., Lavin, Y., Kim-Schulze, S., D'Souza, D., Hamon, P., Dawson, T., Tsankov, A., Rahman, A., Gnjatic, S., Ward, S., Kamphorst, A. O., Giotti, B., Malissen, N., Marron, T. & Fiel, M.
29/08/23
1 item of Media coverage
Press/Media

Alice O. Kamphorst

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Headline

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Collaborations and top research areas from the last five years

Dive into details

An immunocompetent murine model of virus-elicited liver fibrosis and hepatocellular carcinoma

Guidelines for T cell nomenclature

Humoral IgG1 responses to tumor antigens underpin clinical outcomes in immune checkpoint blockade

NOTCH1 Drives Sexually Dimorphic Immune Responses in Hepatocellular Carcinoma

Prolonged but finite antigen presentation promotes reversible defects of “helpless” memory CD8⁺ T cells

Findings on Immunotherapy Detailed by Investigators at Icahn School of Medicine at Mount Sinai (Humoral Igg1 Responses To Tumor Antigens Underpin Clinical Outcomes In Immune Checkpoint Blockade)

New Proteomics Findings from Icahn School of Medicine at Mount Sinai Described (Prolonged but finite antigen presentation promotes reversible defects of "helpless" memory CD8+ T cells)

Studies from Rockefeller University Yield New Data on Lymphocytic Choriomeningitis Virus (Universal Recording of Immune Cell Interactions In Vivo)

Reports on Melanoma from Icahn School of Medicine at Mount Sinai Provide New Insights (Macroh2a Restricts Inflammatory Gene Expression In Melanoma Cancer-associated Fibroblasts By Coordinating Chromatin Looping)

Investigators at Icahn School of Medicine at Mount Sinai Discuss Findings in Liver Cancer [Intratumoral Dendritic Cell-cd4(+) T Helper Cell Niches Enable Cd8(+) T Cell Differentiation Following Pd-1 Blockade In Hepatocellular Carcinoma]

Alice O. Kamphorst

Personal profile

Headline

Fingerprint

Collaborations and top research areas from the last five years

Research output

Press/Media