The Institute for Genomic Health

Icahn School of Medicine at Mount Sinai

Emailigh@mssm.edu
Websitehttps://icahn.mssm.edu/research/institute-genomic-health

Postal addressShow on map
1 Gustave Levy Place, Box 1041
10029 New York, NY
United States

25331 Citations
54 h-index
201 Article
22 Comment/debate
17 Review article
9 Chapter
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Aberrant activation of TCL1A promotes stem cell expansion in clonal haematopoiesis
NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, 1 Apr 2023, In: Nature. 616, 7958, p. 755-763 9 p.
Research output: Contribution to journal › Article › peer-review
4 Scopus citations
ACMG SF v3.2 list for reporting of secondary findings in clinical exome and genome sequencing: A policy statement of the American College of Medical Genetics and Genomics (ACMG)
ACMG Secondary Findings Working Group, Aug 2023, In: Genetics in Medicine. 25, 8, 100866.
Research output: Contribution to journal › Article › peer-review

3 Scopus citations
A draft human pangenome reference
Liao, W. W., Asri, M., Ebler, J., Doerr, D., Haukness, M., Hickey, G., Lu, S., Lucas, J. K., Monlong, J., Abel, H. J., Buonaiuto, S., Chang, X. H., Cheng, H., Chu, J., Colonna, V., Eizenga, J. M., Feng, X., Fischer, C., Fulton, R. S., Garg, S., & 99 othersGroza, C., Guarracino, A., Harvey, W. T., Heumos, S., Howe, K., Jain, M., Lu, T. Y., Markello, C., Martin, F. J., Mitchell, M. W., Munson, K. M., Mwaniki, M. N., Novak, A. M., Olsen, H. E., Pesout, T., Porubsky, D., Prins, P., Sibbesen, J. A., Sirén, J., Tomlinson, C., Villani, F., Vollger, M. R., Antonacci-Fulton, L. L., Baid, G., Baker, C. A., Belyaeva, A., Billis, K., Carroll, A., Chang, P. C., Cody, S., Cook, D. E., Cook-Deegan, R. M., Cornejo, O. E., Diekhans, M., Ebert, P., Fairley, S., Fedrigo, O., Felsenfeld, A. L., Formenti, G., Frankish, A., Gao, Y., Garrison, N. A., Giron, C. G., Green, R. E., Haggerty, L., Hoekzema, K., Hourlier, T., Ji, H. P., Kenny, E. E., Koenig, B. A., Kolesnikov, A., Korbel, J. O., Kordosky, J., Koren, S., Lee, H. J., Lewis, A. P., Magalhães, H., Marco-Sola, S., Marijon, P., McCartney, A., McDaniel, J., Mountcastle, J., Nattestad, M., Nurk, S., Olson, N. D., Popejoy, A. B., Puiu, D., Rautiainen, M., Regier, A. A., Rhie, A., Sacco, S., Sanders, A. D., Schneider, V. A., Schultz, B. I., Shafin, K., Smith, M. W., Sofia, H. J., Abou Tayoun, A. N., Thibaud-Nissen, F., Tricomi, F. F., Wagner, J., Walenz, B., Wood, J. M. D., Zimin, A. V., Bourque, G., Chaisson, M. J. P., Flicek, P., Phillippy, A. M., Zook, J. M., Eichler, E. E., Haussler, D., Wang, T., Jarvis, E. D., Miga, K. H., Garrison, E., Marschall, T., Hall, I. M., Li, H. & Paten, B., 11 May 2023, In: Nature. 617, 7960, p. 312-324 13 p.
Research output: Contribution to journal › Article › peer-review

Open Access
32 Scopus citations
Approaches to Genetic Screening in Cardiomyopathies: Practical Guidance for Clinicians
Kontorovich, A. R., Feb 2023, In: JACC: Heart Failure. 11, 2, p. 133-142 10 p.
Research output: Contribution to journal › Review article › peer-review
2 Scopus citations
Association of HSD17B13 and PNPLA3 With Liver Enzymes and Fibrosis in Hispanic/Latino Individuals of Diverse Genetic Ancestries
Rutledge, S. M., Soper, E. R., Ma, N., Pejaver, V., Friedman, S. L., Branch, A. D., Kenny, E. E., Belbin, G. M. & Abul-Husn, N. S., 2023, (Accepted/In press) In: Clinical Gastroenterology and Hepatology.
Research output: Contribution to journal › Article › peer-review
Author Correction: Clonal haematopoiesis and risk of chronic liver disease (Nature, (2023), 616, 7958, (747-754), 10.1038/s41586-023-05857-4)
NHLBI TOPMed Hematology Working Group, 20 Jul 2023, In: Nature. 619, 7970, p. E47
Research output: Contribution to journal › Comment/debate

Open Access
Causal effects on complex traits are similar for common variants across segments of different continental ancestries within admixed individuals
Hou, K., Ding, Y., Xu, Z., Wu, Y., Bhattacharya, A., Mester, R., Belbin, G. M., Buyske, S., Conti, D. V., Darst, B. F., Fornage, M., Gignoux, C., Guo, X., Haiman, C., Kenny, E. E., Kim, M., Kooperberg, C., Lange, L., Manichaikul, A., North, K. E., & 9 othersPeters, U., Rasmussen-Torvik, L. J., Rich, S. S., Rotter, J. I., Wheeler, H. E., Wojcik, G. L., Zhou, Y., Sankararaman, S. & Pasaniuc, B., Apr 2023, In: Nature Genetics. 55, 4, p. 549-558 10 p.
Research output: Contribution to journal › Article › peer-review
6 Scopus citations
Clinical genetic counseling and translation considerations for polygenic scores in personalized risk assessments: A Practice Resource from the National Society of Genetic Counselors
Wand, H., Kalia, S. S., Helm, B. M., Suckiel, S. A., Brockman, D., Vriesen, N., Goudar, R. K., Austin, J. & Yanes, T., Jun 2023, In: Journal of Genetic Counseling. 32, 3, p. 558-575 18 p.
Research output: Contribution to journal › Article › peer-review
Clonal haematopoiesis and risk of chronic liver disease
NHLBI TOPMed Hematology Working Group, 27 Apr 2023, In: Nature. 616, 7958, p. 747-754 8 p.
Research output: Contribution to journal › Article › peer-review
6 Scopus citations
Cytokinopathy with aberrant cytotoxic lymphocytes and profibrotic myeloid response in SARS-CoV-2 mRNA vaccine–associated myocarditis
Barmada, A., Klein, J., Ramaswamy, A., Brodsky, N. N., Jaycox, J. R., Sheikha, H., Jones, K. M., Habet, V., Campbell, M., Sumida, T. S., Kontorovich, A., Bogunovic, D., Oliveira, C. R., Steele, J., Hall, E. K., Pena-Hernandez, M., Monteiro, V., Lucas, C., Ring, A. M., Omer, S. B., & 3 othersIwasaki, A., Yildirim, I. & Lucas, C. L., May 2023, In: Science immunology. 8, 83, eadh3455.
Research output: Contribution to journal › Article › peer-review

Open Access
5 Scopus citations
Detection of mosaic variants using genome sequencing in a large pediatric cohort
Odgis, J. A., Gallagher, K. M., Rehman, A. U., Marathe, P. N., Bonini, K. E., Sebastin, M., Di Biase, M., Brown, K., Kelly, N. R., Ramos, M. A., Thomas-Wilson, A., Guha, S., Okur, V., Ganapathi, M., Elkhoury, L., Edelmann, L., Zinberg, R. E., Abul-Husn, N. S., Diaz, G. A., Greally, J. M., & 6 othersSuckiel, S. A., Jobanputra, V., Horowitz, C. R., Kenny, E. E., Wasserstein, M. P. & Gelb, B. D., Mar 2023, In: American Journal of Medical Genetics, Part A. 191, 3, p. 699-710 12 p.
Research output: Contribution to journal › Article › peer-review
3 Scopus citations
Disease risk and healthcare utilization among ancestrally diverse groups in the Los Angeles region
Caggiano, C., Boudaie, A., Shemirani, R., Mefford, J., Petter, E., Chiu, A., Ercelen, D., He, R., Tward, D., Paul, K. C., Chang, T. S., Pasaniuc, B., Kenny, E. E., Shortt, J. A., Gignoux, C. R., Balliu, B., Arboleda, V. A., Belbin, G. & Zaitlen, N., Jul 2023, In: Nature Medicine. 29, 7, p. 1845-1856 12 p.
Research output: Contribution to journal › Article › peer-review
1 Scopus citations

Researcher at Icahn School of Medicine at Mount Sinai Releases New Data on Computer Science (Trumpet plots: visualizing the relationship between allele frequency and effect size in genetic association studies)
Paul O'Reilly
14/09/23
1 item of Media coverage
Press/Media
New Nephropathy Study Findings Recently Were Reported by Researchers at Columbia University (Genome-wide Association Analyses Define Pathogenic Signaling Pathways and Prioritize Drug Targets for Iga Nephropathy)
Ali Gharavi, & Eimear Kenny
21/08/23
1 item of Media coverage
Press/Media
Recent Research from Columbia University Highlight Findings in Chronic Kidney Disease (Genomic Disorders In Ckd Across the Lifespan)
Ali Gharavi, & Eimear Kenny
15/08/23
1 item of Media coverage
Press/Media
Researchers from Icahn School of Medicine at Mount Sinai Discuss Findings in Peripheral Artery Disease (Admixture mapping of peripheral artery disease in a Dominican population reveals a putative risk locus on 2q35)
Sinead Cullina, Samira Asgari, Eimear Kenny & Noura Abul-Husn
14/08/23
1 item of Media coverage
Press/Media
Outside the Kidney – New Study Uncovers Unexpected Source of Common Kidney Disease
Ali Gharavi, & Eimear Kenny
9/08/23
1 item of Media coverage
Press/Media
Data on Life Science Reported by Researchers at Stanford University (Aberrant Activation of Tcl1a Promotes Stem Cell Expansion In Clonal Haematopoiesis)
Eimear Kenny
7/08/23
1 item of Media coverage
Press/Media
Is it genetic? What experts say about risk of diabetes, Alzheimer’s and more
Eimear Kenny
25/07/23
1 item of Media coverage
Press/Media
Is it genetic? What experts say about risk of diabetes, Alzheimer's and more
Eimear Kenny
25/07/23
2 items of Media coverage
Press/Media
23andMe Releases New FDA-Cleared Genetic Report on Simvastatin, a Commonly Prescribed Statin
Noura Abul-Husn
20/07/23
3 items of Media coverage
Press/Media
Gene variant may be why some test positive for Covid-19 with no symptoms
Samira Asgari
20/07/23
7 items of Media coverage
Press/Media
Medical finding: why some people do not develop Covid-19 symptoms
Samira Asgari
19/07/23
1 item of Media coverage
Press/Media
Gene variant may be why some test positive for virus with no covid symptoms
Samira Asgari
19/07/23
1 item of Media coverage
Press/Media

The Institute for Genomic Health

Fingerprint

Collaborations and top research areas from the last five years

Dive into details

Noura Abul-Husn

Samira Asgari

Eimear Kenny

Amy Kontorovich

Vikas Pejaver

Aberrant activation of TCL1A promotes stem cell expansion in clonal haematopoiesis

ACMG SF v3.2 list for reporting of secondary findings in clinical exome and genome sequencing: A policy statement of the American College of Medical Genetics and Genomics (ACMG)

A draft human pangenome reference

Approaches to Genetic Screening in Cardiomyopathies: Practical Guidance for Clinicians

Association of HSD17B13 and PNPLA3 With Liver Enzymes and Fibrosis in Hispanic/Latino Individuals of Diverse Genetic Ancestries

Author Correction: Clonal haematopoiesis and risk of chronic liver disease (Nature, (2023), 616, 7958, (747-754), 10.1038/s41586-023-05857-4)

Causal effects on complex traits are similar for common variants across segments of different continental ancestries within admixed individuals

Clinical genetic counseling and translation considerations for polygenic scores in personalized risk assessments: A Practice Resource from the National Society of Genetic Counselors

Clonal haematopoiesis and risk of chronic liver disease

Cytokinopathy with aberrant cytotoxic lymphocytes and profibrotic myeloid response in SARS-CoV-2 mRNA vaccine–associated myocarditis

Detection of mosaic variants using genome sequencing in a large pediatric cohort

Disease risk and healthcare utilization among ancestrally diverse groups in the Los Angeles region

Researcher at Icahn School of Medicine at Mount Sinai Releases New Data on Computer Science (Trumpet plots: visualizing the relationship between allele frequency and effect size in genetic association studies)

New Nephropathy Study Findings Recently Were Reported by Researchers at Columbia University (Genome-wide Association Analyses Define Pathogenic Signaling Pathways and Prioritize Drug Targets for Iga Nephropathy)

Recent Research from Columbia University Highlight Findings in Chronic Kidney Disease (Genomic Disorders In Ckd Across the Lifespan)

Researchers from Icahn School of Medicine at Mount Sinai Discuss Findings in Peripheral Artery Disease (Admixture mapping of peripheral artery disease in a Dominican population reveals a putative risk locus on 2q35)

Outside the Kidney – New Study Uncovers Unexpected Source of Common Kidney Disease

Data on Life Science Reported by Researchers at Stanford University (Aberrant Activation of Tcl1a Promotes Stem Cell Expansion In Clonal Haematopoiesis)

Is it genetic? What experts say about risk of diabetes, Alzheimer’s and more

Is it genetic? What experts say about risk of diabetes, Alzheimer's and more

23andMe Releases New FDA-Cleared Genetic Report on Simvastatin, a Commonly Prescribed Statin

Gene variant may be why some test positive for Covid-19 with no symptoms

Medical finding: why some people do not develop Covid-19 symptoms

Gene variant may be why some test positive for virus with no covid symptoms

The Institute for Genomic Health

Fingerprint

Collaborations and top research areas from the last five years

Profiles

Research output

Press/Media