Ronald M. Loeb Center for Alzheimer’s Disease

329599 Citations
259 h-index
2795 Article
308 Review article
196 Comment/debate
85 Chapter
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A comprehensive suite for extracting neuron signals across multiple sessions in one-photon calcium imaging
Vergara, P., Wang, Y., Srinivasan, S., Dong, Z., Feng, Y., Koyanagi, I., Kumar, D., Chérasse, Y., Naoi, T., Sugaya, Y., Sakurai, T., Kano, M., Shuman, T., Cai, D., Yanagisawa, M. & Sakaguchi, M., Dec 2025, In: Nature Communications. 16, 1, 3443.
Research output: Contribution to journal › Article › peer-review

Open Access
1 Scopus citations
Alzheimer's Association clinical practice guideline for the Diagnostic Evaluation, Testing, Counseling, and Disclosure of Suspected Alzheimer's Disease and Related Disorders (DETeCD-ADRD): Executive summary of recommendations for primary care
Atri, A., Dickerson, B. C., Clevenger, C., Karlawish, J., Knopman, D., Lin, P. J., Norman, M., Onyike, C., Sano, M., Scanland, S. & Carrillo, M., Jun 2025, In: Alzheimer's and Dementia. 21, 6, e14333.
Research output: Contribution to journal › Article › peer-review

Open Access
17 Scopus citations
Alzheimer's disease-associated CD83(+) microglia are linked with increased immunoglobulin G4 and human cytomegalovirus in the gut, vagal nerve, and brain
Readhead, B. P., Mastroeni, D. F., Wang, Q., Sierra, M. A., de Ávila, C., Jimoh, T. O., Haure-Mirande, J. V., Atanasoff, K. E., Nolz, J., Suazo, C., Barton, N. J., Orszulak, A. R., Chigas, S. M., Tran, K., Mirza, A., Ryon, K., Proszynski, J., Najjar, D., Dudley, J. T. & Liu, S. T. H. & 21 others, Gandy, S., Ehrlich, M. E., Alsop, E., Antone, J., Reiman, R., Funk, C., Best, R. L., Jhatro, M., Kamath, K., Shon, J., Kowalik, T. F., Bennett, D. A., Liang, W. S., Serrano, G. E., Beach, T. G., Van Keuren-Jensen, K., Mason, C. E., Chan, Y., Lim, E. T., Tortorella, D. & Reiman, E. M., Jan 2025, In: Alzheimer's and Dementia. 21, 1, e14401.
Research output: Contribution to journal › Article › peer-review

Open Access
5 Scopus citations
Alzheimer's disease risk ABCA7 p.A696S variant disturbs the microglial response to amyloid pathology in mice
Ma, X., Prokopenko, D., Wang, N., Aikawa, T., Choi, Y., Zhang, C., Lei, D., Ren, Y., Kawatani, K., Starling, S. C., Perkerson, R. B., Roy, B., Quintero, A. C., Parsons, T. M., Pan, Y., Li, Z., Wang, M., Bao, H., Han, X. & Bu, G. & 2 others, Tanzi, R. E. & Kanekiyo, T., Mar 2025, In: Neurobiology of Disease. 206, 106813.
Research output: Contribution to journal › Article › peer-review
1 Scopus citations
A macrophage gene-regulatory network linked to clinical severity of coronary artery disease: The STARNET and NGS-PREDICT primary blood macrophage studies
Ma, L., Tamis‑Holland, J. E., Mocci, G., Wolhuter, K., Bryce, N. S., Sajja, S., Amadori, L., Pradhan, P., Chong, P. S., Sukhavasi, K., Cheng, H., Li, L., Pang, S., Schadt, E. E., Schunkert, H., von Scheidt, M., Ruusalepp, A., Moreno, P. R., Hao, K. & Giannarelli, C. & 3 others, Miller, C. L., Kovacic, J. C. & Björkegren, J. L. M., 2025, (Accepted/In press) In: Basic Research in Cardiology.
Research output: Contribution to journal › Article › peer-review
APOE genotype and brain amyloid are associated with changes in the plasma proteome in elderly subjects without dementia
Philippi, S. M., Kailash, B. P., Raj, T. & Castellano, J. M., Feb 2025, In: Annals of Clinical and Translational Neurology. 12, 2, p. 366-382 17 p.
Research output: Contribution to journal › Article › peer-review

Open Access
1 Scopus citations
A Population-Wide Exploration of the THAP11 CAG Repeat Size and Structure in the 100,000 Genomes Project and UK Biobank
Clarkson, C., Chen, Z., Rocca, C., Jadhav, B., Ibañez, K., Ryten, M., Sharp, A. J., Houlden, H. & Tucci, A., Mar 2025, In: Movement Disorders. 40, 3, p. 561-566 6 p.
Research output: Contribution to journal › Article › peer-review

Open Access
1 Scopus citations
Application of new biologic disease criteria for synucleinopathies to the systemic synuclein sampling study cohort
On behalf of the Systemic Synuclein Sampling Study, Dec 2025, In: npj Parkinson's Disease. 11, 1, 69.
Research output: Contribution to journal › Comment/debate
1 Scopus citations
A rapid and robust protocol for generating loss-of-function alleles in pluripotent stem cells
Baljinnyam, E., Grisanti, L., Tattari, S., Pedicone, C., Shewale, B., Dubois, N., Goate, A. M., Kerr, W. G. & Marro, S. G., 19 Sep 2025, In: STAR Protocols. 6, 3, 103916.
Research output: Contribution to journal › Article › peer-review
Arousal threshold modifies the effect of CPAP on executive function among individuals with obstructive sleep apnoea
Zinchuk, A. V., Kushida, C. A., Walker, A., Wellman, A., Azarbarzin, A., Alex, R. M., Varga, A. W., Sands, S. A. & Yaggi, H. K., 2025, In: European Respiratory Journal. 65, 2, 2401183.
Research output: Contribution to journal › Article › peer-review
7 Scopus citations
A structural haplotype in the 17q21.31 MAPT region is associated with increased risk for chronic traumatic encephalopathy endophenotypes
the DIAGNOSE CTE Research Project Investigators, 20 May 2025, In: Cell Reports Medicine. 6, 5, 102084.
Research output: Contribution to journal › Article › peer-review
Author Correction: Modeling gene × environment interactions in PTSD using human neurons reveals diagnosis-specific glucocorticoid-induced gene expression(Nature Neuroscience, 10.1038/s41593-022-01161-y)
NYSCF Global Stem Cell Array® Team, Jan 2025, In: Nature Neuroscience. 28, 1, p. 214 1 p.
Research output: Contribution to journal › Comment/debate

Open Access

Alnylam Pharmaceuticals continues to outperform Incyte by 11.5% in the past month
Sharp, A.
27/05/25
4 items of Media coverage
Press/Media
For opioid addiction, treatment underdosing can lead to fentanyl overdosing – a physician explains
Sharp, A.
27/05/25
13 items of Media coverage
Press/Media
Investigators from Icahn School of Medicine at Mount Sinai Target Traumatic Stress Disorders (Implications of Gene X Environment Interactions In Post-traumatic Stress Disorder Risk and Treatment)
Brennand, K.
26/05/25
1 item of Media coverage
Press/Media
How Alnylam Pharmaceuticals Has Fared Since Its Recent Analyst Ratings Changes
Sharp, A.
23/05/25
1 item of Media coverage
Press/Media
Voices From the Class of 2025 at the Icahn School of Medicine at Mount Sinai’s Commencement
Sazeides, C., Venkatesh, S., Nestler, E. J., Voloudakis, G., Muller, D., Roussos, P., Heller, D., Keefer, L., Parkas, V., Appel, J. & Charney, D.
22/05/25
1 item of Media coverage
Press/Media
Trump condemns anti-Semitism, but some Jews say he uses it to his advantage
Sharp, A.
22/05/25
1 item of Media coverage
Press/Media
How Alnylam Pharmaceuticals's Tax Rate compares to Its Peers
Sharp, A.
22/05/25
1 item of Media coverage
Press/Media
Scientists predict underwater volcano eruption 300 miles off Oregon
Sharp, A.
21/05/25
4 items of Media coverage
Press/Media
Ukraine beats the UK at school lunch reform - and no one saw it coming
Sharp, A.
21/05/25
1 item of Media coverage
Press/Media
Alnylam Pharmaceuticals Continues to Outperform its Peers
Sharp, A.
21/05/25
1 item of Media coverage
Press/Media
Movies playing in Southeast Michigan, new releases May 23
Murray, M. & Sharp, A.
21/05/25
7 items of Media coverage
Press/Media
Ukraine beats the UK at school lunch reform - and no one saw it coming
Sharp, A.
21/05/25
1 item of Media coverage
Press/Media