Projects per year
Fingerprint
Dive into the research topics where Pharmacological Sciences is active. These topic labels come from the works of this organization's members. Together they form a unique fingerprint.
Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Profiles
-
-
-
Dissecting and targeting canonical and non-canonical oncogenic functions of EZH2 in cancer
Wang, G. G. G. G. & Jin, J.
1/01/22 → 31/12/23
Project: Research
-
Elucidating the Molecular Mechanisms that Mediate DKD Progression in Patients Living with HIV
He, J. J. C. & Ma’ayan, A.
National Institute of Diabetes and Digestive and Kidney Diseases
1/12/21 → 30/11/23
Project: Research
-
Biomechanical drivers of cystogenesis
Gusella, L., Azeloglu, E., Azeloglu, E. E. U. & Gusella, L.
National Institute of Diabetes and Digestive and Kidney Diseases
24/09/21 → 31/07/23
Project: Research
-
A novel treatment option for disorders of propionate metabolism
Houten, S., DeVita, R., Houten, S. M. & Devita, R. R. J.
National Institute of Child Health and Human Development
22/09/21 → 31/08/23
Project: Research
-
Skin Biology and Diseases Resource-based Center at Mount Sinai
Ezhkova, E., Bowcock, A. A. M., Bowcock, A. M., Ezhkova, E., Guccione, E. E., Guccione, E., Rendl, M. & Rendl, M.
National Institute of Arthritis and Musculoskeletal and Skin Diseases
1/09/21 → 31/08/23
Project: Research
-
AN INTEGRATED PLATFORM FOR NOVEL PERSONALIZED LIVER CANCER THERAPEUTICS
Dar, A., Lujambio, A., Dar, A., Guccione, E. E., Guccione, E. & Lujambio, A.
1/07/21 → 30/06/23
Project: Research
-
Resource Core D - Bioinformatics and Statistical Analysis Core
Guccione, E. & Guccione, E. E.
National Institute of Arthritis and Musculoskeletal and Skin Diseases
1/07/21 → 31/08/23
Project: Research
-
Substrate reduction as a novel therapeutic strategy for Glutaric Aciduria Type 1
Houten, S., DeVita, R., Houten, S. M. & Devita, R. R. J.
National Institute of Child Health and Human Development
1/05/21 → 30/04/23
Project: Research
Research output
-
An autocrine signaling circuit in hepatic stellate cells underlies advanced fibrosis in nonalcoholic steatohepatitis
Wang, S., Li, K., Pickholz, E., Dobie, R., Matchett, K. P., Henderson, N. C., Carrico, C., Driver, I., Borch Jensen, M., Chen, L., Petitjean, M., Bhattacharya, D., Fiel, M. I., Liu, X., Kisseleva, T., Alon, U., Adler, M., Medzhitov, R. & Friedman, S. L., 4 Jan 2023, In: Science Translational Medicine. 15, 677, p. eadd3949Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
An MDM2 degrader for treatment of acute leukemias
Marcellino, B. K., Yang, X., Ümit Kaniskan, H., Brady, C., Chen, H., Chen, K., Qiu, X., Clementelli, C., Herschbein, L., Li, Z., Elghaity-Beckley, S., Arandela, J., Kelly, B., Hoffman, R., Liu, J., Xiong, Y., Jin, J. & Shih, A. H., Feb 2023, In: Leukemia. 37, 2, p. 370-378 9 p.Research output: Contribution to journal › Article › peer-review
-
A Regional and Projection-Specific Role of RGSz1 in the Ventrolateral Periaqueductal Grey in the Modulation of Morphine Reward
Sakloth, F., Sanchez-Reyes, O. B., Ruiz, A., Nicolais, A., Serafini, R. A., Pryce, K. D., Bertherat, F., Torres-Berrío, A., Gomes, I., Devi, L. A., Wacker, D. & Zachariou, V., 1 Jan 2023, In: Molecular Pharmacology. 103, 1, p. 1-8 8 p.Research output: Contribution to journal › Article › peer-review
Open Access -
BRD4-PRC2 represses transcription of T-helper 2-specific negative regulators during T-cell differentiation
Zhao, L., Wang, Y., Jaganathan, A., Sun, Y., Ma, N., Li, N., Han, X., Sun, X., Yi, H., Fu, S., Han, F., Li, X., Xiao, K., Walsh, M. J., Zeng, L., Zhou, M. M. & Cheung, K. L., 2023, (Accepted/In press) In: EMBO Journal.Research output: Contribution to journal › Article › peer-review
Open Access -
Discovery and characterization of antidepressant mediated activation of 5-HT1E and 5-HT1F receptors
Zilberg, G., Warren, A. L., Parpounas, A. & Wacker, D., 10 Feb 2023, In: Biophysical Journal. 122, 3S1, p. 195aResearch output: Contribution to journal › Article › peer-review
-
Discovery of the First Lactate Dehydrogenase Proteolysis Targeting Chimera Degrader for the Treatment of Pancreatic Cancer
Sun, N., Kabir, M., Lee, Y., Xie, L., Hu, X., Velez, J., Chen, X., Kaniskan, H. Ü. & Jin, J., 12 Jan 2023, In: Journal of Medicinal Chemistry. 66, 1, p. 596-610 15 p.Research output: Contribution to journal › Article › peer-review
-
Dissecting and targeting noncanonical functions of EZH2 in multiple myeloma via an EZH2 degrader
Yu, X., Wang, J., Gong, W., Ma, A., Shen, Y., Zhang, C., Liu, X., Cai, L., Liu, J., Wang, G. G. & Jin, J., 2023, (Accepted/In press) In: Oncogene.Research output: Contribution to journal › Article › peer-review
-
G9a/GLP inhibition during ex vivo lymphocyte expansion increases in vivo cytotoxicity of engineered T cells against hepatocellular carcinoma
Lam, M. S. Y., Reales-Calderon, J. A., Ow, J. R., Aw, J. J. Y., Tan, D., Vijayakumar, R., Ceccarello, E., Tabaglio, T., Lim, Y. T., Chien, W. L., Lai, F., Tanoto, A. T., Chen, Q., Sobota, R. M., Adriani, G., Bertoletti, A., Guccione, E. & Pavesi, A., Dec 2023, In: Nature Communications. 14, 1, 563.Research output: Contribution to journal › Article › peer-review
Open Access -
Histone H3 dopaminylation in nucleus accumbens, but not medial prefrontal cortex, contributes to cocaine-seeking following prolonged abstinence
Stewart, A. F., Lepack, A. L., Fulton, S. L., Safovich, P. & Maze, I., Jun 2023, In: Molecular and Cellular Neurosciences. 125, 103824.Research output: Contribution to journal › Article › peer-review
Open Access -
Modeling the spatiotemporal properties of crosstalk between RYR and IP3R-mediated Ca2+release in failing cardiomyocytes
Jones, D. A. C. & Sobie, E. A., 10 Feb 2023, In: Biophysical Journal. 122, 3S1, p. 165aResearch output: Contribution to journal › Article › peer-review
-
Molecular states during acute COVID-19 reveal distinct etiologies of long-term sequelae
The Mount Sinai COVID-19 Biobank Team, Jan 2023, In: Nature Medicine. 29, 1, p. 236-246 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Noradrenergic modulation of stress resilience
Zhai, X., Zhou, D., Han, Y., Han, M. H. & Zhang, H., Jan 2023, In: Pharmacological Research. 187, 106598.Research output: Contribution to journal › Review article › peer-review
Open Access
Press/Media
-
Icahn School of Medicine at Mount Sinai Researchers Update Current Study Findings on Pain (Spinal Cord Sensitization and Spinal Inflammation from an In Vivo Rat Endplate Injury Associated with Painful Intervertebral Disc Degeneration)
Alon Lai, James Iatridis & Venetia Zachariou
13/03/23
1 item of Media coverage
Press/Media
-
FABA holding virtual workshop on drug discovery from March 13
11/03/23
1 item of Media coverage
Press/Media
-
Australia Patent: Icahn School of Medicine at Mount Sinai Files Application for 'Compositions and methods for treating EZH2-mediated cancer'
ANQI MA , Jian Jin & Ramon Parsons
25/03/22 → 10/03/23
2 items of Media coverage
Press/Media
-
Australia Patent: Application for 'Serine threonine kinase (AKT) degradation / disruption compounds and methods of use' Lapses
Xufen Yu, Jing Liu, Ramon Parsons & Jian Jin
10/03/23
1 item of Media coverage
Press/Media
-
-
How AI can help create and optimize drugs to treat opioid addiction
22/02/23
1 item of Media coverage
Press/Media
-
AI Helps Create Drug to Combat Opioid Addiction, Researcher Develops
20/02/23
1 item of Media coverage
Press/Media
-
How AI Can Help Create and Optimize Drugs To Treat Opioid Addiction
20/02/23
3 items of Media coverage
Press/Media
-
Study reveals how artificial intelligence can help treat opioid addiction
18/02/23 → 19/02/23
16 items of Media coverage
Press/Media
-
University of North Carolina Chapel Hill Researchers Highlight Research in Ewing Sarcoma (MS0621, a novel small-molecule modulator of Ewing sarcoma chromatin accessibility, interacts with an RNA-associated macromolecular complex and influences ...)
Yan Xiong & Jian Jin
14/02/23
1 item of Media coverage
Press/Media