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Collaborations and top research areas from the last five years
Profiles
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Michael S Breen
- Graduate School of Biomedical Sciences
- Friedman Brain Institute
- Genetics and Genomic Sciences
- Icahn Genomics Institute
- Icahn School of Medicine at Mount Sinai
- Mindich Child Health and Development Institute
- Pamela Sklar Division of Psychiatric Genomics
- Psychiatry
- Seaver Autism Center for Research and Treatment
Person
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Alexander Charney
- Mount Sinai Academy of Physician-Scientists
- Artificial Intelligence and Human Health
- Friedman Brain Institute
- Genetics and Genomic Sciences
- Graduate School of Biomedical Sciences
- Hasso Plattner Institute for Digital Health at Mount Sinai
- Icahn Genomics Institute
- Icahn School of Medicine at Mount Sinai
- Jeff and Lisa Blau Adolescent Consultation Center for Resilience and Treatment
- Mount Sinai Clinical Intelligence Institute
- Nash Family Center for Advanced Circuit Therapeutics
- Pamela Sklar Division of Psychiatric Genomics
- Psychiatry
Person
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Panos Roussos
- Artificial Intelligence and Human Health
- Friedman Brain Institute
- Genetics and Genomic Sciences
- Graduate School of Biomedical Sciences
- Icahn Genomics Institute
- Icahn School of Medicine at Mount Sinai
- Pamela Sklar Division of Psychiatric Genomics
- Psychiatry
- Ronald M. Loeb Center for Alzheimer’s Disease
Person
Research output
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3D genetic architecture of schizophrenia risk across three neuronal subtypes
Powell, S. K., Liao, W., Ghorbani, S., Rigat, R., O’Shea, C., Kammourh, S., Elahi, R., Infante, D., Deans, P. M., Le, D. J., Agarwal, P., Qiang Seow, W., Balafkan, N., Wang, K. C., Akbarian, S. & Brennand, K. J., Apr 2026, In: Molecular Psychiatry. 31, 4, p. 2216-2231 16 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Are There Causal Associations Between Obsessive-Compulsive Disorder and Cardiometabolic Phenotypes? A Genetic Correlation and Bi-Directional Mendelian Randomization Study
Obsessive-Compulsive Disorder Working Group of the Psychiatric Genomics Consortium, Jul 2026, In: American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 201, 5, p. 321-330 10 p.Research output: Contribution to journal › Article › peer-review
Open Access -
A study of gene expression in the living human brain
Liharska, L. E., Park, Y. J., Ziafat, K., Wilkins, L., Silk, H., Linares, L. M., Thompson, R. C., Vornholt, E., Sullivan, B., Cohen, V., Kota, P., Feng, C., Cheng, E., Johnson, J. S., Rieder, M. K., Huang, J., Scarpa, J., Polanco, J., Moya, E. & Hashemi, A. & 8 others, , Jan 2026, In: Molecular Psychiatry. 31, 1, p. 137-157 21 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
A transcriptional program associated with neurotransmission in the living human brain
Charney, A. W., Liharska, L. E., Vornholt, E., Valentine, A., Lund, A., Hashemi, A., Thompson, R. C., Lohrenz, T., Johnson, J. S., Bussola, N., Cheng, E., Park, Y. J., Qasim, S., Aristel, A., Wilkins, L., Ziafat, K., Silk, H., Linares, L. M., Sullivan, B. & Feng, C. & 18 others, , May 2026, In: Molecular Psychiatry. 31, 5, p. 2727-2738 12 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Biological insights into schizophrenia from ancestrally diverse populations
VA Million Veteran Program (MVP), Project Among African-Americans to Explore Risks for Schizophrenia (PAARTNERS), Consortium on the Genomics of Schizophrenia (COGS), Genomic Psychiatry Cohort (GPC) Investigators, PsychAD Consortium & VA Cooperative Studies Program (CSP) #572, 12 Mar 2026, In: Nature. 651, 8105, p. 404-413 10 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
ChatGPT Health performance in a structured test of triage recommendations
Ramaswamy, A., Tyagi, A., Hugo, H., Jiang, J., Jayaraman, P., Jangda, M., Te, A. E., Kaplan, S. A., Lampert, J., Freeman, R., Gavin, N., Tewari, A. K., Sakhuja, A., Naved, B., Charney, A. W., Omar, M., Gorin, M. A., Klang, E. & Nadkarni, G. N., May 2026, In: Nature Medicine. 32, 5, p. 1671-1675 5 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Clinical agents fail silently on patient identity
Klang, E., Glicksberg, B. S., Gorenshtein, A., Gavin, N., Freeman, R., Stump, L., Charney, A. W., Wei Ting, D. S., Omar, M. & Nadkarni, G. N., 15 Sep 2026, In: International Journal of Medical Informatics. 218, 106514.Research output: Contribution to journal › Article › peer-review
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Dynamic Alterations in the Blood Transcriptome Characterize Drug Use Behavior and Co-Morbidities in Cocaine Use Disorder: A Preliminary Study
Nwaneshiudu, C., Girdhar, K., Kleopoulos, S., Shao, Z., Fullard, J., Butelman, E., Parvaz, M., Goldstein, R., Alia-Klein, N. & Roussos, P., Feb 2026, In: European Journal of Neuroscience. 63, 3, e70409.Research output: Contribution to journal › Article › peer-review
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Establishing the relationship between brain cellular senescence and brain structure
Lund, A. N., Kopell, B. H., Golestani, N., Vornholt, E., Thompson, R. C., Liharska, L. E., Luo, Y., Cheng, E., Park, Y. J., Fennessy, B., Wilkins, L., Kaji, D. A., Silk, H., Ziafat, K., Hashemi, A., Moya, E., Feng, C., Linares, L. M., Grice, A. B. & Xie, S. & 19 others, , 22 Jan 2026, In: Cell. 189, 2, p. 511-527.e17Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Functional implications of polygenic risk for schizophrenia in human neurons
Michael Deans, P. J., Retallick-Townsley, K. G., Li, A., Seah, C., Johnson, J., Garcia Gonzalez, J., Cao, E., Schrode, N., Yu, A., Cartwright, S., Voloudakis, G., Zhang, W., Wang, M., Fullard, J. F., Girdhar, K., Stahl, E., Akbarian, S., Zhang, B., Roussos, P. & O’Reilly, P. & 2 others, , Dec 2026, In: Nature Communications. 17, 1, 1355.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Integrating multiomic layers to decode psychiatric disease mechanisms
Sheu, L., Girdhar, K. & Roussos, P., Jun 2026, In: Current Opinion in Genetics and Development. 98, 102451.Research output: Contribution to journal › Review article › peer-review
Open Access -
Large language models are poor clinical administrators: An evaluation of structured queries in real-world electronic health records
Klang, E., Sorin, V., Korfiatis, P., Sawant, A. S., Freeman, R., Charney, A. W., Nadkarni, G. N. & Glicksberg, B. S., May 2026, In: PLOS Digital Health. 5, 5 May, e0001326.Research output: Contribution to journal › Article › peer-review
Open Access
Press/Media
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HMN 2026: How Extreme trait values may trace to rare genes with outsized effects,
O'Reilly, P. & O'Reilly, P.
11/06/26
1 item of Media coverage
Press/Media
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Riding the New Wave of AI in Health Care
Nadkarni, G., Glicksberg, B., Charney, A., Ensari, I. & Freeman, R.
4/06/26
1 item of Media coverage
Press/Media
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Live-Imaging Techniques Reveal How Stem Cells Collectively Suppress Tumors
Brennand, K.
2/06/26
2 items of Media coverage
Press/Media
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At the Extremes, Human Traits May Have Different Genetic Basis
O'Reilly, P. & O'Reilly, P.
27/05/26 → 28/05/26
6 items of Media coverage
Press/Media
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Genetic Foundations of Human Traits May Vary at the Extremes
O'Reilly, P. & O'Reilly, P.
27/05/26
2 items of Media coverage
Press/Media
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Yale University: Many Genes Have Been Linked to Autism - But Study Suggests It May Be Their Path to the Brain That Matters
Brennand, K.
1/05/26 → 6/05/26
4 items of Media coverage
Press/Media
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New Findings from Icahn School of Medicine at Mount Sinai in the Area of Schizophrenia Reported (Downregulated transcription in chromosomal domains of midbrain dopamine neurons linked to schizophrenia)
Akbarian, S., Wang, M., Roussos, P., Girdhar, K. & Hoffman, G.
20/04/26
1 item of Media coverage
Press/Media
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Sheba, Mount Sinai, and NVIDIA partner to decode the poorly understood 98% of the human genome
12/04/26
1 item of Media coverage
Press/Media
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HMN 2026: How early RNA editing shifts may reshape fetal brain circuits
11/04/26
1 item of Media coverage
Press/Media
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Yale University: Zebrafish Reveal Insights Into the Biology of Autism
Brennand, K.
2/04/26 → 8/04/26
5 items of Media coverage
Press/Media