Nanomedicine

1 Active
10 Finished

PET nanoreporter image-guided breast cancer therapy
Fayad, Z., Mulder, W., Perez-Medina, C., Grimm, J. J., Mulder, W., Perez-Medina, C. & Reiner, T.
National Cancer Institute
15/06/18 → 31/05/23
Project: Research
Inhibition of trained immunity in atherosclerosis and ischemic heart disease.
van Leent, M.
American Heart Association
1/01/19 → 31/12/20
Project: Research
TRAF6 Nanoimmunotherapy to resolve plaque inflammation
Fayad, Z. & Mulder, W.
National Heart, Lung, and Blood Institute
15/08/18 → 30/06/20
Project: Research
Integration of classical and contemporary views on atherosclerosis using highly innovative PET/MR plaque phenotyping.
Senders, M.
American Heart Association
1/07/17 → 30/06/19
Project: Research
Stress and Atherosclerotic Plaque Macrophages - A Systems Biology Approach
Fayad, Z., Mani, V., Mulder, W. & Swirski, F.
National Heart, Lung, and Blood Institute
17/03/17 → 28/02/22
Project: Research
Translational imaging and nanomedicine in inflammatory atherosclerosis
Mulder, W.
National Heart, Lung, and Blood Institute
1/09/16 → 28/02/22
Project: Research
'Atherosclerosis phenotyping and targeted treatment by nanoreporter PET imaging'
Perez-Medina, C.
American Heart Association
1/07/16 → 30/06/19
Project: Research
Atherosclerosis phenotyping and targeted treatment by nanoreporter PET imaging
Perez-Medina, C.
American Heart Association
1/07/16 → 30/06/19
Project: Research
PET/MRI to study nanotherapy in atherosclerosis
Mulder, W.
National Heart, Lung, and Blood Institute
14/11/14 → 30/11/18
Project: Research
Anti-inflammatory nanoparticle formulations to treat atherosclerosis
Mulder, W. & Nahrendorf, M.
National Heart, Lung, and Blood Institute
1/09/14 → 30/06/18
Project: Research
A Surface Activable Nanoemulsion platform for Breast Cancer Diagnosis and Therapy
Mulder, W.
National Cancer Institute
1/09/11 → 31/07/16
Project: Research

11981 Citations
64 h-index
121 Article
38 Review article
7 Editorial
6 Comment/debate
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In vivo imaging of cerebral glucose metabolism informs on subacute to chronic post-stroke tissue status – A pilot study combining PET and deuterium metabolic imaging
Meerwaldt, A. E., Straathof, M., Oosterveld, W., van Heijningen, C. L., van Leent, M. M. T., Toner, Y. C., Munitz, J., Teunissen, A. J. P., Daemen, C. C., van der Toorn, A., van Vliet, G., van Tilborg, G. A. F., De Feyter, H. M., de Graaf, R. A., Hol, E. M., Mulder, W. J. M. & Dijkhuizen, R. M., 2023, (Accepted/In press) In: Journal of Cerebral Blood Flow and Metabolism.
Research output: Contribution to journal › Article › peer-review

Open Access
Self-gated, dynamic contrast-enhanced magnetic resonance imaging with compressed-sensing reconstruction for evaluating endothelial permeability in the aortic root of atherosclerotic mice
Calcagno, C., David, J. A., Motaal, A. G., Coolen, B. F., Beldman, T., Corbin, A., Kak, A., Ramachandran, S., Pruzan, A., Sridhar, A., Soler, R., Faries, C. M., Fayad, Z. A., Mulder, W. J. M. & Strijkers, G. J., Jan 2023, In: NMR in Biomedicine. 36, 1, e4823.
Research output: Contribution to journal › Article › peer-review

Open Access
Trained immunity — basic concepts and contributions to immunopathology
Ochando, J., Mulder, W. J. M., Madsen, J. C., Netea, M. G. & Duivenvoorden, R., Jan 2023, In: Nature Reviews Nephrology. 19, 1, p. 23-37 15 p.
Research output: Contribution to journal › Review article › peer-review

Open Access
FSH-blocking therapeutic for osteoporosis
Gera, S., Kuo, T. C., Gumerova, A. A., Korkmaz, F., Sant, D., Demambro, V., Sudha, K., Padilla, A., Prevot, G., Munitz, J., Teunissen, A., van Leent, M. M. T., Post, T. G. J. M., Fernandes, J. C., Netto, J., Sultana, F., Shelly, E., Rojekar, S., Kumar, P., Cullen, L., & 26 othersChatterjee, J., Pallapati, A., Miyashita, S., Kannangara, H., Bhongade, M., Sengupta, P., Ievleva, K., Muradova, V., Batista, R., Robinson, C., Macdonald, A., Hutchison, S., Saxena, M., Meseck, M., Caminis, J., Iqbal, J., New, M. I., Ryu, V., Kim, S. M., Cao, J. J., Zaidi, N., Fayad, Z. A., Lizneva, D., Rosen, C. J., Yuen, T. & Zaidi, M., Sep 2022, In: eLife. 11, e78022.
Research output: Contribution to journal › Article › peer-review

Open Access
PET/MR imaging of inflammation in atherosclerosis
Senders, M. L., Calcagno, C., Tawakol, A., Nahrendorf, M., Mulder, W. J. M. & Fayad, Z. A., 2022, (Accepted/In press) In: Nature Biomedical Engineering.
Research output: Contribution to journal › Article › peer-review
Regulating trained immunity with nanomedicine
van Leent, M. M. T., Priem, B., Schrijver, D. P., de Dreu, A., Hofstraat, S. R. J., Zwolsman, R., Beldman, T. J., Netea, M. G. & Mulder, W. J. M., Jun 2022, In: Nature Reviews Materials. 7, 6, p. 465-481 17 p.
Research output: Contribution to journal › Review article › peer-review

Open Access
12 Scopus citations
Reprogramming of myeloid cells and their progenitors in patients with non-medullary thyroid carcinoma
Rabold, K., Zoodsma, M., Grondman, I., Kuijpers, Y., Bremmers, M., Jaeger, M., Zhang, B., Hobo, W., Bonenkamp, H. J., de Wilt, J. H. W., Janssen, M. J. R., Cornelissen, L. A. M., van Engen-van Grunsven, I. C. H., Mulder, W. J. M., Smit, J. W. A., Adema, G. J., Netea, M. G., Li, Y., Xu, C. J. & Netea-Maier, R. T., Dec 2022, In: Nature Communications. 13, 1, 6149.
Research output: Contribution to journal › Article › peer-review

Open Access
1 Scopus citations
Systematically evaluating DOTATATE and FDG as PET immuno-imaging tracers of cardiovascular inflammation
Toner, Y. C., Ghotbi, A. A., Naidu, S., Sakurai, K., van Leent, M. M. T., Jordan, S., Ordikhani, F., Amadori, L., Sofias, A. M., Fisher, E. L., Maier, A., Sullivan, N., Munitz, J., Senders, M. L., Mason, C., Reiner, T., Soultanidis, G., Tarkin, J. M., Rudd, J. H. F., Giannarelli, C., & 6 othersOchando, J., Pérez-Medina, C., Kjaer, A., Mulder, W. J. M., Fayad, Z. A. & Calcagno, C., Dec 2022, In: Scientific Reports. 12, 1, 6185.
Research output: Contribution to journal › Article › peer-review

Open Access
2 Scopus citations
A modular approach toward producing nanotherapeutics targeting the innate immune system
van Leent, M. M. T., Meerwaldt, A. E., Berchouchi, A., Toner, Y. C., Burnett, M. E., Klein, E. D., Verschuur, A. V. D., Nauta, S. A., Munitz, J., Prévot, G., van Leeuwen, E. M., Ordikhani, F., Mourits, V. P., Calcagno, C., Robson, P. M., Soultanidis, G., Reiner, T., Joosten, R. R. M., Friedrich, H., Madsen, J. C., & 9 othersKluza, E., van der Meel, R., Joosten, L. A. B., Netea, M. G., Ochando, J., Fayad, Z. A., Pérez-Medina, C., Mulder, W. J. M. & Teunissen, A. J. P., 3 Mar 2021, In: Science advances. 7, 10, eabe7853.
Research output: Contribution to journal › Article › peer-review

Open Access
9 Scopus citations
Author Correction: Trained immunity, tolerance, priming and differentiation: distinct immunological processes (Nature Immunology, (2021), 22, 1, (2-6), 10.1038/s41590-020-00845-6)
Divangahi, M., Aaby, P., Khader, S. A., Barreiro, L. B., Bekkering, S., Chavakis, T., van Crevel, R., Curtis, N., DiNardo, A. R., Dominguez-Andres, J., Duivenvoorden, R., Fanucchi, S., Fayad, Z., Fuchs, E., Hamon, M., Jeffrey, K. L., Khan, N., Joosten, L. A. B., Kaufmann, E., Latz, E., & 24 othersMatarese, G., van der Meer, J. W. M., Mhlanga, M., Moorlag, S. J. C. F. M., Mulder, W. J. M., Naik, S., Novakovic, B., O’Neill, L., Ochando, J., Ozato, K., Riksen, N. P., Sauerwein, R., Sherwood, E. R., Schlitzer, A., Schultze, J. L., Sieweke, M. H., Benn, C. S., Stunnenberg, H., Sun, J., van de Veerdonk, F. L., Weis, S., Williams, D. L., Xavier, R. & Netea, M. G., Jul 2021, In: Nature Immunology. 22, 7, p. 928 1 p.
Research output: Contribution to journal › Comment/debate

Open Access
4 Scopus citations
Cyclic Arginine–Glycine–Aspartate-Decorated Lipid Nanoparticle Targeting toward Inflammatory Lesions Involves Hitchhiking with Phagocytes
Sofias, A. M., Bjørkøy, G., Ochando, J., Sønstevold, L., Hegvik, M., Davies, C. D. L., Haraldseth, O., Lammers, T., Mulder, W. J. M. & Hak, S., 7 Jul 2021, In: Advanced Science. 8, 13, 2100370.
Research output: Contribution to journal › Article › peer-review

Open Access
6 Scopus citations
Diverse ultrastructural landscape of atherosclerotic endothelium
Kluza, E., Beldman, T. J., Shami, A., Scholl, E. R., Malinova, T. S., Grootemaat, A. E., van der Wel, N. N., Gonçalves, I., Huveneers, S., Mulder, W. J. M. & Lutgens, E., Dec 2021, In: Atherosclerosis. 339, p. 35-45 11 p.
Research output: Contribution to journal › Article › peer-review

Open Access
4 Scopus citations

Interview Roy van der Meel develops RNA nanotechnology. ‘I’m a kind of postie who delivers medicines’
Willem Mulder
27/12/22
1 item of Media coverage
Press/Media
Recent Findings in Life Science Described by Researchers from Icahn School of Medicine at Mount Sinai (Trained Immunity - Basic Concepts and Contributions To Immunopathology)
Willem Mulder & Jordi Ochando
10/11/22
1 item of Media coverage
Press/Media
Willem Mulder appointed professor of Precision Medicine
Willem Mulder
4/10/22
2 items of Media coverage
Press/Media
Australia Patent: ICahn School of Medicine at Mount Sinai Files Application for 'TARGETING THE INNATE IMMUNE SYSTEM TO INDUCE LONG-TERM TOLERANCE AND TO RESOLVE MACROPHAGE ACCUMULATION IN ATHEROSCLEROSIS'
Willem Mulder, Jordi Ochando & Zahi Fayad
16/09/22
1 item of Media coverage
Press/Media
Australian Patent Office Grants Patent for 'Targeting the innate immune system to induce long-term tolerance and to resolve macrophage accumulation in atherosclerosis'
Willem Mulder, Jordi Ochando & Zahi Fayad
29/07/22
1 item of Media coverage
Press/Media
Australia Patent: ICahn School of Medicine at Mount Sinai Files Application for 'TARGETING THE INNATE IMMUNE SYSTEM TO INDUCE LONG-TERM TOLERANCE AND TO RESOLVE MACROPHAGE ACCUMULATION IN ATHEROSCLEROSIS'
Willem Mulder, Jordi Ochando & Zahi Fayad
15/07/22
1 item of Media coverage
Press/Media
Australia: Icahn School of Medicine at Mount Sinai Receives Patent for 'Targeting the innate immune system to induce long-term tolerance and to resolve macrophage accumulation in atherosclerosis'
Willem Mulder, Jordi Ochando & Zahi Fayad
1/04/22
1 item of Media coverage
Press/Media
Immune Cells That Remember Inflammation Could Offer Treatment Targets for Atherosclerosis
Willem Mulder
1/12/21
1 item of Media coverage
Press/Media
Banning journal impact factors is bad for Dutch science
Willem Mulder
3/08/21
1 item of Media coverage
Press/Media
TU/e and Radboudumc join forces with creation of biomedical platform Biotrip
Willem Mulder
30/06/21 → 7/07/21
2 items of Media coverage
Press/Media
Eindhoven University of Technology and Radboudumc Join Forces With Creation of Biomedical Platform Biotrip
Willem Mulder
30/06/21 → 1/07/21
2 items of Media coverage
Press/Media
TTXD appoints Nobel Laureate Dr. James Allison, Dr. Padmanee Sharma, and Dr. Mihai Netea to Scientific Advisory Board
Willem Mulder
19/04/21
4 items of Media coverage
Press/Media

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