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Dive into the research topics where Mount Sinai Institute for Systems Biomedicine is active. These topic labels come from the works of this organization's members. Together they form a unique fingerprint.
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Profiles
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Paul Kenny
- Center for Neurotechnology and Behavior
- Addiction Institute of Mount Sinai
- Brain-Body Center
- Center for Affective Neuroscience
- Friedman Brain Institute
- Graduate School of Biomedical Sciences
- Icahn School of Medicine at Mount Sinai
- Mount Sinai Drug Discovery Institute
- Mount Sinai Institute for Systems Biomedicine
- Nash Family Department of Neuroscience
- Psychiatry
- Ronald M. Loeb Center for Alzheimer’s Disease
Person
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James Murrough
- BioMedical Engineering and Imaging Institute
- Brain-Body Center
- Center for Affective Neuroscience
- Depression and Anxiety Center
- Friedman Brain Institute
- Graduate School of Biomedical Sciences
- Icahn School of Medicine at Mount Sinai
- Mount Sinai Academy of Physician-Scientists
- Mount Sinai Institute for Systems Biomedicine
- Nash Family Center for Advanced Circuit Therapeutics
- Psychiatry
Person
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Scott Russo
- Center for Neurotechnology and Behavior
- Addiction Institute of Mount Sinai
- Brain-Body Center
- Cardiovascular Research Institute
- Center for Affective Neuroscience
- Friedman Brain Institute
- Graduate School of Biomedical Sciences
- Icahn School of Medicine at Mount Sinai
- Mount Sinai Institute for Systems Biomedicine
- Nash Family Department of Neuroscience
- Psychiatry
Person
Research output
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A critical residue mediates proper assembly and gating of GIRK2 channels
Nguyen, H., Mount, J., Hutchinson, K., Zhao, Y., Zhao, Y., Glaaser, I. W., Yuan, P., Schlessinger, A. & Slesinger, P. A., 5 Jan 2026, In: Journal of General Physiology. 158, 1Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Adipokine Metabolic Drivers, Gut Dysbiosis, and the Prostate Microbiome: Novel Pathway Enrichment Analysis of the Adiposity-Based Chronic Disease—Prostate Cancer Network
Dovey, Z., Tomas Bort, E. & Mechanick, J. I., Jan 2026, In: Cancers. 18, 2, 206.Research output: Contribution to journal › Review article › peer-review
Open Access -
BOLD-GPCRs: A Transformer-Powered App for Predicting Ligand Bioactivity and Mutational Effects across Class A GPCRs
Provasi, D., Konovalov, K., Riina, N., Cullen, O. & Filizola, M., 26 Jan 2026, In: Journal of Chemical Information and Modeling. 66, 2, p. 855-866 12 p.Research output: Contribution to journal › Article › peer-review
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Computer-aided structural modeling and drug discovery for G-protein-coupled receptors in the age of artificial intelligence
Novack, S. & Filizola, M., Jun 2026, In: Current Opinion in Structural Biology. 98, 103248.Research output: Contribution to journal › Article › peer-review
Open Access -
Cross-Organ Neuroimmunology of Behavior
Guo, X. & Russo, S. J., 2026, In: Annual Review of Immunology. 44, 1, p. 437-465 29 p.Research output: Contribution to journal › Review article › peer-review
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Gut-brain cholinergic signaling mediates the antiseizure effects of Bacteroides fragilis
Jia, Y., Chen, H., Zou, Q., Chen, S., Li, J., Chen, Y., Lu, L., Hong, F., Jia, S., Jing, X., Ren, J., Muhammad, F., Mi, J. Y., Duan, J., Liao, J., Liu, Q., Xu, F., Kenny, P. J., Han, M. H. & Wang, L. & 3 others, , 18 Mar 2026, In: Neuron. 114, 6, p. 1021-1044.e9Research output: Contribution to journal › Article › peer-review
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Identification of small molecule ligands for GPR83 that modulate morphine antinociception and reward
Gomes, I., Mack, S. M., Sanchez, R., Yadav, A., Duarte, M. L., Devi, L. A. & Fakira, A. K., Jan 2026, In: Molecular Pharmacology. 108, 1, 100092.Research output: Contribution to journal › Article › peer-review
Open Access -
Immunity in Rodent Models of Stress
Hachenberg, S., Russo, S. J. & Cathomas, F., 2026, (Accepted/In press) In: Biological Psychiatry.Research output: Contribution to journal › Review article › peer-review
Open Access -
KET-MCI: A Pilot Safety and Tolerability Study of Single Infusion Intravenous Ketamine for Older Adults with Depression and Mild Cognitive Impairment
Fremont, R., Karim, A., Estevez, T. P., McDonough, C., LaBarbiera, A., Feder, A., Naasan, G., Delgado, A., Charney, D. S. & Murrough, J. W., 2026, (Accepted/In press) In: American Journal of Geriatric Psychiatry.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Leveraging single-cell spatial transcriptomics and connectomics to resolve brain circuit function in psychiatry
Claypool, S. M. & Kenny, P. J., Jan 2026, In: Neuropsychopharmacology. 51, 1, p. 364-365 2 p.Research output: Contribution to journal › Comment/debate
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Major depressive disorder shares systemic immune signatures and potential therapeutic targets with inflammatory skin diseases
He, H., Cathomas, F., Parise, L. F., David, E., Rizk, M., Hawkins, K., Karpman, E., Russo, S. J., Guttman, E. & Murrough, J. W., May 2026, In: Molecular Psychiatry. 31, 5, p. 2498-2508 11 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Microenvironmental cell interactions are essential for sustaining functionality of myelofibrosis malignant stem cells
Lu, M., Mia, M. B., Xia, L., Mosoyan, G., Hayat, M., Schaniel, C. & Hoffman, R., 12 Mar 2026, In: Blood. 147, 11, p. 1215-1228 14 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations
Press/Media
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Reemphasizing Nutrition and Diet in Managing Chronic Endocrine Disease, With Jeffrey Mechanick, MD
23/04/26
1 item of Media coverage
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Reemphasizing Nutrition and Diet in Managing Chronic Endocrine Diseases: Insights from Jeffrey Mechanick, MD
23/04/26
1 item of Media coverage
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Kv7 Channel Modulator Shows Promise for Anhedonia in MDD, With James Murrough, MD
16/04/26
1 item of Media coverage
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Researchers from Icahn School of Medicine at Mount Sinai Describe Findings in Major Depressive Disorder (Machine learning framework for depression subtype grouping: integrating high-resolution imaging and clinical symptom analysis via ...)
Verma, G., Jacob, Y., Murrough, J., Morris, L., Balchandani, P. & Delman, B.
16/04/26
1 item of Media coverage
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Reports Outline Drug Research Study Results from Rachel Fremont et al (KET-MCI: A Pilot Safety and Tolerability Study of Single Infusion Intravenous Ketamine for Older Adults with Depression and Mild Cognitive Impairment)
Delgado, A., Murrough, J., Naasan, G., Charney, D. & Feder, A.
13/04/26
1 item of Media coverage
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Kv7 Channel Modulator Azetukalner May Improve Anhedonia, With James Murrough, MD, PhD
9/04/26
1 item of Media coverage
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Is a new weight-loss drug making people fall out of love?
6/04/26
4 items of Media coverage
Press/Media