Mount Sinai Global Health and Emerging Pathogens Institute

Research output

Research output per year 1992 2010 2013 2020 2021 2022 2023

• 76930 Citations
• 136 h-index
• 739 Article
• 58 Review article
• 42 Comment/debate
• 20 Letter
• 28 More
  • 11 Chapter
  • 11 Short survey
  • 6 Editorial

Research output per year

Research output per year

Search results

• 2023

  Virology under the Microscope-a Call for Rational Discourse

  Goodrum, F., Lowen, A. C., Lakdawala, S., Alwine, J., Casadevall, A., Imperiale, M. J., Atwood, W., Avgousti, D., Baines, J., Banfield, B., Banks, L., Bhaduri-McIntosh, S., Bhattacharya, D., Blanco-Melo, D., Bloom, D., Boon, A., Boulant, S., Brandt, C., Broadbent, A., Brooke, C., & 136 othersCameron, C., Campos, S., Caposio, P., Chan, G., Cliffe, A., Coffin, J., Collins, K., Damania, B., Daugherty, M., Debbink, K., DeCaprio, J., Dermody, T., Dikeakos, J., DiMaio, D., Dinglasan, R., Duprex, W. P., Dutch, R., Elde, N., Emerman, M., Enquist, L., Fane, B., Fernandez-Sesma, A., Flenniken, M., Frappier, L., Frieman, M., Frueh, K., Gack, M., Gaglia, M., Gallagher, T., Galloway, D., García-Sastre, A., Geballe, A., Glaunsinger, B., Goff, S., Greninger, A., Hancock, M., Harris, E., Heaton, N., Heise, M., Heldwein, E., Hogue, B., Horner, S., Hutchinson, E., Hyser, J., Jackson, W., Kalejta, R., Kamil, J., Karst, S., Kirchhoff, F., Knipe, D., Kowalik, T., Lagunoff, M., Laimins, L., Langlois, R., Lauring, A., Lee, B., Leib, D., Liu, S. L., Longnecker, R., Lopez, C., Luftig, M., Lund, J., Manicassamy, B., McFadden, G., McIntosh, M., Mehle, A., Miller, W. A., Mohr, I., Moody, C., Moorman, N., Moscona, A., Mounce, B., Munger, J., Münger, K., Murphy, E., Naghavi, M., Nelson, J., Neufeldt, C., Nikolich, J., O'Connor, C., Ono, A., Orenstein, W., Ornelles, D., Ou, J. H., Parker, J., Parrish, C., Pekosz, A., Pellett, P., Pfeiffer, J., Plemper, R., Polyak, S., Purdy, J., Pyeon, D., Quinones-Mateu, M., Renne, R., Rice, C., Schoggins, J., Roller, R., Russell, C., Sandri-Goldin, R., Sapp, M., Schang, L., Schmid, S., Schultz-Cherry, S., Semler, B., Shenk, T., Silvestri, G., Simon, V., Smith, G., Smith, J., Spindler, K., Stanifer, M., Subbarao, K., Sundquist, W., Suthar, M., Sutton, T., Tai, A., Tarakanova, V., tenOever, B., Tibbetts, S., Tompkins, S., Toth, Z., van Doorslaer, K., Vignuzzi, M., Wallace, N., Walsh, D., Weekes, M., Weinberg, J., Weitzman, M., Weller, S., Whelan, S., White, E., Williams, B., Wobus, C., Wong, S. & Yurochko, A., Jan 2023, In: mBio. 14, 1

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Virology 100%
  • SARS Virus 45%
  • Viruses 20%
  • Pandemics 16%
  • Administrative Personnel 15%

• Virology under the Microscope—a Call for Rational Discourse

  Goodrum, F., Lowen, A. C., Lakdawala, S., Alwine, J., Casadevall, A., Imperiale, M. J., Atwood, W., Avgousti, D., Baines, J., Banfield, B., Banks, L., Bhaduri-McIntosh, S., Bhattacharya, D., Blanco-Melo, D., Bloom, D., Boon, A., Boulant, S., Brandt, C., Broadbent, A., Brooke, C., & 136 othersCameron, C., Campos, S., Caposio, P., Chan, G., Cliffe, A., Coffin, J., Collins, K., Damania, B., Daugherty, M., Debbink, K., DeCaprio, J., Dermody, T., Dikeakos, J., DiMaio, D., Dinglasan, R., Duprex, W. P., Dutch, R., Elde, N., Emerman, M., Enquist, L., Fane, B., Fernandez-Sesma, A., Flenniken, M., Frappier, L., Frieman, M., Frueh, K., Gack, M., Gaglia, M., Gallagher, T., Galloway, D., García-Sastre, A., Geballe, A., Glaunsinger, B., Goff, S., Greninger, A., Hancock, M., Harris, E., Heaton, N., Heise, M., Heldwein, E., Hogue, B., Horner, S., Hutchinson, E., Hyser, J., Jackson, W., Kalejta, R., Kamil, J., Karst, S., Kirchhoff, F., Knipe, D., Kowalik, T., Lagunoff, M., Laimins, L., Langlois, R., Lauring, A., Lee, B., Leib, D., Liu, S. L., Longnecker, R., Lopez, C., Luftig, M., Lund, J., Manicassamy, B., McFadden, G., McIntosh, M., Mehle, A., Miller, W. A., Mohr, I., Moody, C., Moorman, N., Moscona, A., Mounce, B., Munger, J., Münger, K., Murphy, E., Naghavi, M., Nelson, J., Neufeldt, C., Nikolich, J., O'Connor, C., Ono, A., Orenstein, W., Ornelles, D., Ou, J. H., Parker, J., Parrish, C., Pekosz, A., Pellett, P., Pfeiffer, J., Plemper, R., Polyak, S., Purdy, J., Pyeon, D., Quinones-Mateu, M., Renne, R., Rice, C., Schoggins, J., Roller, R., Russell, C., Sandri-Goldin, R., Sapp, M., Schang, L., Schmid, S., Schultz-Cherry, S., Semler, B., Shenk, T., Silvestri, G., Simon, V., Smith, G., Smith, J., Spindler, K., Stanifer, M., Subbarao, K., Sundquist, W., Suthar, M., Sutton, T., Tai, A., Tarakanova, V., tenOever, B., Tibbetts, S., Tompkins, S., Toth, Z., van Doorslaer, K., Vignuzzi, M., Wallace, N., Walsh, D., Weekes, M., Weinberg, J., Weitzman, M., Weller, S., Whelan, S., White, E., Williams, B., Wobus, C., Wong, S. & Yurochko, A., Feb 2023, In: Journal of Virology. 97, 2

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • virology 100%
  • Virology 97%
  • SARS Virus 44%
  • burden of disease 22%
  • Viruses 20%
• 2022

  Advances and gaps in SARS-CoV-2 infection models

  Muñoz-Fontela, C., Widerspick, L., Albrecht, R. A., Beer, M., Carroll, M. W., de Wit, E., Diamond, M. S., Dowling, W. E., Funnell, S. G. P., García-Sastre, A., Gerhards, N. M., de Jong, R., Munster, V. J., Neyts, J., Perlman, S., Reed, D. S., Richt, J. A., Riveros-Balta, X., Roy, C. J., Salguero, F. J., & 7 othersSchotsaert, M., Schwartz, L. M., Seder, R. A., Segalés, J., Vasan, S. S., Henao-Restrepo, A. M. & Barouch, D. H., Jan 2022, In: PLoS Pathogens. 18, 1, e1010161.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • SARS Virus 100%
  • World Health Organization 83%
  • Animal Models 48%
  • animal models 39%
  • vaccines 38%
  19 Scopus citations

• Defining the risk of SARS-CoV-2 variants on immune protection

  DeGrace, M. M., Ghedin, E., Frieman, M. B., Krammer, F., Grifoni, A., Alisoltani, A., Alter, G., Amara, R. R., Baric, R. S., Barouch, D. H., Bloom, J. D., Bloyet, L. M., Bonenfant, G., Boon, A. C. M., Boritz, E. A., Bratt, D. L., Bricker, T. L., Brown, L., Buchser, W. J., Carreño, J. M., & 110 othersCohen-Lavi, L., Darling, T. L., Davis-Gardner, M. E., Dearlove, B. L., Di, H., Dittmann, M., Doria-Rose, N. A., Douek, D. C., Drosten, C., Edara, V. V., Ellebedy, A., Fabrizio, T. P., Ferrari, G., Fischer, W. M., Florence, W. C., Fouchier, R. A. M., Franks, J., García-Sastre, A., Godzik, A., Gonzalez-Reiche, A. S., Gordon, A., Haagmans, B. L., Halfmann, P. J., Ho, D. D., Holbrook, M. R., Huang, Y., James, S. L., Jaroszewski, L., Jeevan, T., Johnson, R. M., Jones, T. C., Joshi, A., Kawaoka, Y., Kercher, L., Koopmans, M. P. G., Korber, B., Koren, E., Koup, R. A., LeGresley, E. B., Lemieux, J. E., Liebeskind, M. J., Liu, Z., Livingston, B., Logue, J. P., Luo, Y., McDermott, A. B., McElrath, M. J., Meliopoulos, V. A., Menachery, V. D., Montefiori, D. C., Mühlemann, B., Munster, V. J., Munt, J. E., Nair, M. S., Netzl, A., Niewiadomska, A. M., O’Dell, S., Pekosz, A., Perlman, S., Pontelli, M. C., Rockx, B., Rolland, M., Rothlauf, P. W., Sacharen, S., Scheuermann, R. H., Schmidt, S. D., Schotsaert, M., Schultz-Cherry, S., Seder, R. A., Sedova, M., Sette, A., Shabman, R. S., Shen, X., Shi, P. Y., Shukla, M., Simon, V., Stumpf, S., Sullivan, N. J., Thackray, L. B., Theiler, J., Thomas, P. G., Trifkovic, S., Türeli, S., Turner, S. A., Vakaki, M. A., van Bakel, H., VanBlargan, L. A., Vincent, L. R., Wallace, Z. S., Wang, L., Wang, M., Wang, P., Wang, W., Weaver, S. C., Webby, R. J., Weiss, C. D., Wentworth, D. E., Weston, S. M., Whelan, S. P. J., Whitener, B. M., Wilks, S. H., Xie, X., Ying, B., Yoon, H., Zhou, B., Hertz, T., Smith, D. J., Diamond, M. S., Post, D. J. & Suthar, M. S., 26 May 2022, In: Nature. 605, 7911, p. 640-652 13 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Severe Acute Respiratory Syndrome 100%
  • Coronavirus 97%
  • Immunity 31%
  • Vaccines 29%
  • National Institute of Allergy and Infectious Diseases (U.S.) 19%
  25 Scopus citations

• Lung Cancer and Severe Acute Respiratory Syndrome Coronavirus 2 Infection: Identifying Important Knowledge Gaps for Investigation

  Rolfo, C., Meshulami, N., Russo, A., Krammer, F., García-Sastre, A., Mack, P. C., Gomez, J. E., Bhardwaj, N., Benyounes, A., Sirera, R., Moore, A., Rohs, N., Henschke, C. I., Yankelevitz, D., King, J., Shyr, Y., Bunn, P. A., Minna, J. D. & Hirsch, F. R., Feb 2022, In: Journal of Thoracic Oncology. 17, 2, p. 214-227 14 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Coronavirus Infections 100%
  • Severe Acute Respiratory Syndrome 90%
  • Lung Neoplasms 55%
  • Coronavirus 54%
  • Antibody Formation 14%
  12 Scopus citations

• Mucosal delivery of RNA vaccines by Newcastle disease virus vectors

  García-Sastre, A., Jan 2022, In: Current Research in Immunology. 3, p. 234-238 5 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Disease Vectors 100%
  • Newcastle disease virus 93%
  • SARS Virus 63%
  • Vaccines 51%
  • RNA 47%

• Type I and Type II Interferon Antagonism Strategies Used by Paramyxoviridae: Previous and New Discoveries, in Comparison

  Pisanelli, G., Pagnini, U., Iovane, G. & García-Sastre, A., May 2022, In: Viruses. 14, 5, 1107.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Paramyxoviridae 100%
  • interferon type III 67%
  • Interferons 57%
  • Interferon-gamma 55%
  • Interferon Type I 49%
  2 Scopus citations
• 2021

  After the pandemic: perspectives on the future trajectory of COVID-19

  Telenti, A., Arvin, A., Corey, L., Corti, D., Diamond, M. S., García-Sastre, A., Garry, R. F., Holmes, E. C., Pang, P. S. & Virgin, H. W., 26 Aug 2021, In: Nature. 596, 7873, p. 495-504 10 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Coronavirus 100%
  • Pandemics 84%
  • Severe Acute Respiratory Syndrome 81%
  • Epidemics 41%
  • Viruses 31%
  144 Scopus citations

• Control of Innate Immune Activation by Severe Acute Respiratory Syndrome Coronavirus 2 and Other Coronaviruses

  Kehrer, T., Garciá-Sastre, A. & Miorin, L., Jun 2021, In: Journal of Interferon and Cytokine Research. 41, 6, p. 205-219 15 p.

  Research output: Contribution to journal › Review article › peer-review

  • Severe Acute Respiratory Syndrome 100%
  • Coronavirus 97%
  • Interferons 35%
  • Middle East Respiratory Syndrome Coronavirus 29%
  • SARS Virus 28%
  2 Scopus citations

• Unconventional viral gene expression mechanisms as therapeutic targets

  Ho, J. S. Y., Zhu, Z. & Marazzi, I., 20 May 2021, In: Nature. 593, 7859, p. 362-371 10 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Viral Genes 100%
  • Viruses 57%
  • Gene Expression 51%
  • Genome Size 30%
  • Human Genome 22%
  15 Scopus citations
• 2020

  Animal models for COVID-19

  Muñoz-Fontela, C., Dowling, W. E., Funnell, S. G. P., Gsell, P. S., Riveros-Balta, A. X., Albrecht, R. A., Andersen, H., Baric, R. S., Carroll, M. W., Cavaleri, M., Qin, C., Crozier, I., Dallmeier, K., de Waal, L., de Wit, E., Delang, L., Dohm, E., Duprex, W. P., Falzarano, D., Finch, C. L., & 44 othersFrieman, M. B., Graham, B. S., Gralinski, L. E., Guilfoyle, K., Haagmans, B. L., Hamilton, G. A., Hartman, A. L., Herfst, S., Kaptein, S. J. F., Klimstra, W. B., Knezevic, I., Krause, P. R., Kuhn, J. H., Le Grand, R., Lewis, M. G., Liu, W. C., Maisonnasse, P., McElroy, A. K., Munster, V., Oreshkova, N., Rasmussen, A. L., Rocha-Pereira, J., Rockx, B., Rodríguez, E., Rogers, T. F., Salguero, F. J., Schotsaert, M., Stittelaar, K. J., Thibaut, H. J., Tseng, C. T., Vergara-Alert, J., Beer, M., Brasel, T., Chan, J. F. W., García-Sastre, A., Neyts, J., Perlman, S., Reed, D. S., Richt, J. A., Roy, C. J., Segalés, J., Vasan, S. S., Henao-Restrepo, A. M. & Barouch, D. H., 22 Oct 2020, In: Nature. 586, 7830, p. 509-515 7 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Coronavirus 100%
  • Severe Acute Respiratory Syndrome 61%
  • Animal Models 57%
  • Vaccines 35%
  • Pandemics 16%
  409 Scopus citations

• Current Status of COVID-19 (Pre)Clinical Vaccine Development

  Ye, T., Zhong, Z., García-Sastre, A., Schotsaert, M. & De Geest, B. G., 19 Oct 2020, In: Angewandte Chemie - International Edition. 59, 43, p. 18885-18897 13 p.

  Research output: Contribution to journal › Review article › peer-review

  • Vaccines 100%
  51 Scopus citations

• Host immune response–inspired development of the influenza vaccine

  Choi, A., García-Sastre, A. & Schotsaert, M., Jul 2020, In: Annals of Allergy, Asthma and Immunology. 125, 1, p. 28-35 8 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Influenza Vaccines 100%
  • Orthomyxoviridae 33%
  • Human Influenza 20%
  • Vaccination 17%
  • Vaccines 16%
  8 Scopus citations

• Human Virus Transcriptional Regulators

  Liu, X., Hong, T., Parameswaran, S., Ernst, K., Marazzi, I., Weirauch, M. T. & Fuxman Bass, J. I., 9 Jul 2020, In: Cell. 182, 1, p. 24-37 14 p.

  Research output: Contribution to journal › Review article › peer-review

  • Viruses 100%
  • Catalogs 93%
  • Protein 61%
  • Virology 48%
  • Viral Genes 43%
  17 Scopus citations
• 2019

  Moving from empirical to rational vaccine design in the ‘Omics’ era

  Sharma, M., Krammer, F., García-Sastre, A. & Tripathi, S., Sep 2019, In: Vaccines. 7, 3, 89.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Adjuvant 100%
  • Antigen 67%
  • Vaccines 60%
  • Adaptive Immunity 54%
  • Innate Immunity 49%
  15 Scopus citations
• 2018

  Chromatin dependencies in cancer and inflammation

  Marazzi, I., Greenbaum, B. D., Low, DI. H. P. & Guccione, E., 1 Apr 2018, In: Nature Reviews Molecular Cell Biology. 19, 4, p. 245-261 17 p.

  Research output: Contribution to journal › Review article › peer-review

  • Chromatin 100%
  • Inflammation 66%
  • Neoplasms 36%
  • Oncogenes 17%
  • Cell- and Tissue-Based Therapy 17%
  43 Scopus citations

• Influenza

  Krammer, F., Smith, G. J. D., Fouchier, R. A. M., Peiris, M., Kedzierska, K., Doherty, P. C., Palese, P., Shaw, M. L., Treanor, J., Webster, R. G. & García-Sastre, A., 1 Dec 2018, In: Nature Reviews Disease Primers. 4, 1, p. 1-21 21 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Human Influenza 100%
  • Influenza Vaccines 82%
  • Pandemics 77%
  • Epidemics 31%
  • Antiviral Agents 31%
  529 Scopus citations

• RNase III Nucleases and the Evolution of Antiviral Systems

  Aguado, L. C. & tenOever, B. R., Feb 2018, In: BioEssays. 40, 2, 1700173.

  Research output: Contribution to journal › Review article › peer-review

  • Ribonuclease III 100%
  • Antiviral Agents 56%
  • RNA 46%
  • Chordata 24%
  • Genetic Phenomena 22%
  8 Scopus citations
• 2017

  Inactivated influenza virus vaccines: the future of TIV and QIV

  Schotsaert, M. & García-Sastre, A., 1 Apr 2017, In: Current Opinion in Virology. 23, p. 102-106 5 p.

  Research output: Contribution to journal › Review article › peer-review

  • Inactivated Vaccines 100%
  • Influenza Vaccines 91%
  • Attenuated Vaccines 42%
  • Human Influenza 21%
  • Vaccines 17%
  19 Scopus citations

• Reducing the global burden of HTLV-1 infection: An agenda for research and action

  Willems, L., Hasegawa, H., Accolla, R., Bangham, C., Bazarbachi, A., Bertazzoni, U., Carneiro-Proietti, A. B. D. F., Cheng, H., Chieco-Bianchi, L., Ciminale, V., Coelho-dos-Reis, J., Esparza, J., Gallo, R. C., Gessain, A., Gotuzzo, E., Hall, W., Harford, J., Hermine, O., Jacobson, S., Macchi, B., & 10 othersMacpherson, C., Mahieux, R., Matsuoka, M., Murphy, E., Peloponese, J. M., Simon, V., Tagaya, Y., Taylor, G. P., Watanabe, T. & Yamano, Y., 1 Jan 2017, In: Antiviral Research. 137, p. 41-48 8 p.

  Research output: Contribution to journal › Review article › peer-review

  • HTLV-I Infections 100%
  • Human T-lymphotropic virus 1 80%
  • Tropical Spastic Paraparesis 23%
  • Adult T Cell Leukemia Lymphoma 21%
  • Spinal Cord Diseases 18%
  87 Scopus citations

• Ten Strategies of Interferon Evasion by Viruses

  García-Sastre, A., 9 Aug 2017, In: Cell Host and Microbe. 22, 2, p. 176-184 9 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • interferons 100%
  • Interferons 81%
  • Viruses 58%
  • viruses 57%
  • Antiviral Agents 43%
  228 Scopus citations

• TRIM25 in the regulation of the antiviral innate immunity

  Martín-Vicente, M., Medrano, L. M., Resino, S., García-Sastre, A. & Martínez, I., 22 Sep 2017, In: Frontiers in Immunology. 8, SEP, 1187.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Innate Immunity 100%
  • Antiviral Agents 92%
  • IFIH1 Interferon-Induced Helicase 65%
  • TNF Receptor-Associated Factor 6 52%
  • Pattern Recognition Receptors 45%
  74 Scopus citations
• 2016

  Screening transplant donors for HTLV-1 and -2

  Global Virus Network's Task Force on HTLV-1, 29 Dec 2016, In: Blood. 128, 26, p. 3029-3031 3 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access
  29 Scopus citations

• The Evolution of Antiviral Defense Systems

  tenOever, B. R., 2016, In: Cell Host and Microbe. 19, 2, p. 142-149 8 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Antiviral Agents 100%
  • Nucleic Acids 57%
  • Genes 46%
  • coevolution 42%
  • Viruses 38%
  92 Scopus citations
• 2015

  Against the clock towards new Ebola virus therapies

  Martínez-Romero, C. & García-Sastre, A., 2 Nov 2015, In: Virus Research. 209, p. 4-10 7 p.

  Research output: Contribution to journal › Review article › peer-review

  • Ebolavirus 100%
  • Disease Outbreaks 65%
  • Ebola Vaccines 31%
  • Ebola Hemorrhagic Fever 25%
  • Western Africa 23%
  10 Scopus citations

• Expected and Unexpected Features of the Newly Discovered Bat Influenza A-like Viruses

  Ma, W., García-Sastre, A. & Schwemmle, M., 1 Jun 2015, In: PLoS Pathogens. 11, 6, e1004819.

  Research output: Contribution to journal › Review article › peer-review

  Open Access
  29 Scopus citations

• Interference of viral effector proteins with chromatin, transcription, and the epigenome

  Marazzi, I. & Garcia-Sastre, A., 2015, In: Current Opinion in Microbiology. 26, p. 123-129 7 p.

  Research output: Contribution to journal › Review article › peer-review

  • Epigenome 100%
  • Viral Proteins 85%
  • Chromatin 70%
  • Virulence Factors 41%
  • Proteins 29%
  12 Scopus citations

• Intrinsic host restrictions to HIV-1 and mechanisms of viral escape

  Simon, V., Bloch, N. & Landau, N. R., 19 May 2015, In: Nature Immunology. 16, 6, p. 546-553 8 p.

  Research output: Contribution to journal › Review article › peer-review

  • Primate Lentiviruses 100%
  • HIV-1 53%
  • Viral Regulatory and Accessory Proteins 51%
  • Bone Marrow Stromal Antigen 2 50%
  • Antiviral Agents 26%
  200 Scopus citations

• Small hydrophobic protein of respiratory syncytial virus as a novel vaccine antigen

  Schepens, B., Schotsaert, M. & Saelens, X., 1 Mar 2015, In: Immunotherapy. 7, 3, p. 203-206 4 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access
  9 Scopus citations

• The therapeutic effect of death: Newcastle disease virus and its antitumor potential

  Cuadrado-Castano, S., Sanchez-Aparicio, M. T., García-Sastre, A. & Villar, E., 2 Nov 2015, In: Virus Research. 209, p. 56-66 11 p.

  Research output: Contribution to journal › Review article › peer-review

  • Newcastle disease virus 100%
  • Therapeutic Uses 60%
  • Apoptosis 44%
  • Parthanatos 22%
  • Autophagic Cell Death 17%
  25 Scopus citations
• 2014

  Activation and regulation of pathogen sensor RIG-I

  Patel, J. R. & García-Sastre, A., 1 Oct 2014, In: Cytokine and Growth Factor Reviews. 25, 5, p. 513-523 11 p.

  Research output: Contribution to journal › Review article › peer-review

  • Innate Immunity 100%
  • Antimicrobial Agent 75%
  • Pattern Recognition Receptors 68%
  • Double-Stranded RNA 65%
  • triphosphoric acid 63%
  38 Scopus citations

• Influenza vaccines: A moving interdisciplinary field

  Schotsaert, M. & García-Sastre, A., 9 Oct 2014, In: Viruses. 6, 10, p. 3809-3826 18 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Influenza Vaccines 100%
  • Vaccines 65%
  • Orthomyxoviridae 19%
  • Human Influenza 17%
  • Antigenic Variation 13%
  18 Scopus citations

• TRIMmunity: The roles of the TRIM E3-ubiquitin ligase family in innate antiviral immunity

  Rajsbaum, R., García-Sastre, A. & Versteeg, G. A., 20 Mar 2014, In: Journal of Molecular Biology. 426, 6, p. 1265-1284 20 p.

  Research output: Contribution to journal › Review article › peer-review

  • Ubiquitin-Protein Ligases 100%
  • Innate Immunity 80%
  • Antiviral Agents 75%
  • Tripartite Motif Proteins 35%
  • Viral Proteins 23%
  223 Scopus citations
• 2013

  Is RNA interference a physiologically relevant innate antiviral immune response in mammals?

  Cullen, B. R., Cherry, S. & Tenoever, B. R., 16 Oct 2013, In: Cell Host and Microbe. 14, 4, p. 374-378 5 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • plant parasitic nematodes 100%
  • RNA interference 89%
  • RNA Interference 83%
  • Innate Immunity 80%
  • arthropods 80%
  96 Scopus citations

• Novel vaccine strategies against emerging viruses

  García-Sastre, A. & Mena, I., Apr 2013, In: Current Opinion in Virology. 3, 2, p. 210-216 7 p.

  Research output: Contribution to journal › Review article › peer-review

  • Vaccines 100%
  • Viruses 88%
  • Cross Protection 47%
  • Inactivated Vaccines 41%
  • Attenuated Vaccines 41%
  27 Scopus citations

• RNA viruses and the host microRNA machinery

  Tenoever, B. R., Mar 2013, In: Nature Reviews Microbiology. 11, 3, p. 169-180 12 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • RNA Viruses 100%
  • MicroRNAs 74%
  • RNA 61%
  • Chordata 48%
  • Viruses 14%
  108 Scopus citations

• Viral evasion mechanisms of early antiviral responses involving regulation of ubiquitin pathways

  Rajsbaum, R. & García-Sastre, A., Aug 2013, In: Trends in Microbiology. 21, 8, p. 421-429 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • Ubiquitin 100%
  • Antiviral Agents 85%
  • Viruses 53%
  • Innate Immunity 18%
  • Proteins 14%
  51 Scopus citations
• 2012

  Influenza A viruses and PI3K: are there time, place and manner restrictions?

  Ayllon, J., García-Sastre, A. & Hale, B. G., 1 Jul 2012, In: Virulence. 3, 4, p. 411-414 4 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access
  16 Scopus citations
• 2011

  Implications of RNA virus-produced miRNAs

  Varble, A. & TenOever, B. R., 2011, In: RNA Biology. 8, 2

  Research output: Contribution to journal › Review article › peer-review

  • RNA Viruses 100%
  • MicroRNAs 74%
  • Sindbis Virus 15%
  • Nuclear RNA 14%
  • DNA Viruses 13%
  15 Scopus citations

• Induction and evasion of type I interferon responses by influenza viruses

  García-Sastre, A., Dec 2011, In: Virus Research. 162, 1-2, p. 12-18 7 p.

  Research output: Contribution to journal › Review article › peer-review

  • Interferon Type I 100%
  • Orthomyxoviridae 84%
  • Influenza A virus 46%
  • Antiviral Agents 36%
  • Influenza B virus 28%
  167 Scopus citations

• Influenza A viruses: New research developments

  Medina, R. A. & García-Sastre, A., Aug 2011, In: Nature Reviews Microbiology. 9, 8, p. 590-603 14 p.

  Research output: Contribution to journal › Review article › peer-review

  • Influenza A virus 100%
  • Pandemics 64%
  • Viruses 60%
  • Viral Tropism 45%
  • Birds 32%
  438 Scopus citations
• 2010

  Evasion of innate and adaptive immune responses by influenza A virus

  Schmolke, M. & García-Sastre, A., Jul 2010, In: Cellular Microbiology. 12, 7, p. 873-880 8 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Influenza A virus 100%
  • Adaptive Immunity 92%
  • Innate Immunity 83%
  • Immune Evasion 38%
  • Mammals 26%
  71 Scopus citations

• Immune mechanisms of HIV control

  Chakrabarti, L. A. & Simon, V., Aug 2010, In: Current Opinion in Immunology. 22, 4, p. 488-496 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • HIV-1 100%
  • HIV 79%
  • Active Immunity 58%
  • AIDS Vaccines 49%
  • Protective Factors 41%
  33 Scopus citations

• Induction of type i interferon by RNA viruses: Cellular receptors and their substrates

  Baum, A. & García-Sastre, A., May 2010, In: Amino Acids. 38, 5, p. 1283-1299 17 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Virus Receptors 100%
  • Retinoic Acid 96%
  • Inducer 85%
  • RNA Viruses 83%
  • Interferons 67%
  103 Scopus citations

• Innate immune evasion strategies of influenza viruses

  Hale, B. G., Albrecht, R. A. & García-Sastre, A., Jan 2010, In: Future Microbiology. 5, 1, p. 23-41 19 p.

  Research output: Contribution to journal › Review article › peer-review

  • Immune Evasion 100%
  • Orthomyxoviridae 80%
  • Viruses 35%
  • Pandemics 28%
  • Virulence 23%
  123 Scopus citations

• The IKK kinases: Operators of ativiral signaling

  Pham, A. M. & tenOever, B. R., Jan 2010, In: Viruses. 2, 1, p. 55-72 18 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Phosphotransferases 100%
  • Interferon-beta 89%
  • Antiviral Agents 88%
  • Aptitude 35%
  • Psychology Reinforcement 27%
  16 Scopus citations

• Viral tricks to grid-lock the type I interferon system

  Versteeg, G. A. & García-Sastre, A., Aug 2010, In: Current Opinion in Microbiology. 13, 4, p. 508-516 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • Interferon Type I 100%
  • Interferons 77%
  • Viruses 31%
  • Innate Immunity 8%
  • Antiviral Agents 8%
  205 Scopus citations
• 2007

  Recombinant influenza virus vectors

  Martínez-Sobrido, L. & García-Sastre, A., Jul 2007, In: Future Virology. 2, 4, p. 401-416 16 p.

  Research output: Contribution to journal › Review article › peer-review

  • Orthomyxoviridae 100%
  • Human Influenza 91%
  • Viral Proteins 70%
  • Glycoproteins 56%
  • Vaccines 49%
  5 Scopus citations
• 2006

  Antiviral response in pandemic influenza viruses

  García-Sastre, A., Jan 2006, In: Emerging Infectious Diseases. 12, 1, p. 44-47 4 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Pandemics 100%
  • Orthomyxoviridae 94%
  • Antiviral Agents 80%
  • Viruses 62%
  • Viral Regulatory and Accessory Proteins 52%
  63 Scopus citations

• Lessons learned from reconstructing the 1918 influenza pandemic

  García-Sastre, A. & Whitley, R. J., 1 Nov 2006, In: Journal of Infectious Diseases. 194, SUPPL. 2, p. S127-S132

  Research output: Contribution to journal › Review article › peer-review

  • Pandemics 100%
  • Orthomyxoviridae 94%
  • Human Influenza 86%
  • Virulence 81%
  • Influenza in Birds 57%
  33 Scopus citations